Targeting cholesterol metabolism in the eye might help prevent a severe form of age-related macular degeneration (AMD), one of the most common causes of blindness in older Americans, according to indications in a study in mice, which was supported by the National Institutes of Health. Cholesterol build-up in arteries and veins, or atherosclerosis, occurs as a natural consequence of aging. Likewise, in AMD, cholesterol is known to accumulate in the eye, within deposits called drusen. The study, published in Cell Metabolism, shows that large cells called macrophages ...

Although bladder cancer is the sixth most common form of cancer in the U.S. and the most expensive to treat, the basic method that doctors use to treat it hasn't changed much in more than 70 years. An interdisciplinary collaboration of engineers and doctors at Vanderbilt and Columbia Universities intends to change that situation dramatically. Headed by Nabil Simaan, associate professor of mechanical engineering at Vanderbilt, the team has developed a prototype telerobotic platform designed to be inserted through natural orifices – in this case the urethra – that can provide ...

PHILADELPHIA — Poly (ADP-ribose) polymerase inhibitors may be a novel treatment strategy for patients with cancer that has become resistant to the commonly used chemotherapy drug cisplatin, according to data from a preclinical study published in Cancer Research, a journal of the American Association for Cancer Research. "Cisplatin is one of the most widely used conventional, anticancer chemotherapy drugs," said Guido Kroemer, M.D., Ph.D., professor at University Paris Descartes in Paris, France. "Unfortunately, most patients respond only transiently to cisplatin therapy ...

Distracted driving is a primary offense in Pennsylvania Article provided by Aaroe Law Offices Visit us at http://www.settledontsue.com Being distracted from the task of driving is extremely dangerous for motorists and their passengers. Despite reported accidents that result from this practice, many drivers continue to take substantial risks. These careless, inattentive motorists are not only teens, but also skilled adult drivers. Because motorists of all ages continue to multitask behind the wheel, lawmakers have no choice but to implement laws. In modern times, ...

Study further explains dangers of drinking and driving Article provided by Harting Simkins & Ryan LLP Visit us at http://www.hsrlegal.com A recent study has revealed just how dangerous it is to get behind the wheel while under the influence of alcohol. The study, which was published in the journal Alcohol, revealed the affect of alcohol on connections in the brain that control muscle and visual movements. The researchers conducted tests on 14 individuals, measuring their visual and muscle control when sober and when under the influence of alcohol. Each participant ...

Study shows young Americans have higher credit card debt than older generations Article provided by Law Offices of Hagen & Hagen Visit us at http://www.hagenhagenlaw.com Many Americans continue to struggle financially, despite reports that the economy is in an upswing. In many cases, to help prevent imminent financial hardship, people have amassed credit card debts to help them get through this difficult time. According to a study conducted by The Ohio State University, certain groups of people are more likely to take on large amounts of credit card debt ...

No signs that the "gray divorce" trend will be slowing Article provided by Anthony C. Williams & Associates, PC Visit us at http://www.anthonywilliamslaw.com The overall divorce rate in America has lessened in recent years. More couples than ever before are working through their differences and staying together. That doesn't apply to one segment of the population, though. The "baby boomer" generation - couples over the age of 50 - are divorcing at record high rates. The rate of divorce for couples in their 50s and 60s has more than doubled ...

W.Va. scholars suggest disabling cellphones in vehicles Article provided by Brewer & Giggenbach, PLLC Visit us at http://www.bglawhelp.com Distracted driving has become a serious problem on our roads in West Virginia and across the country. According to the National Highway Traffic Safety Administration, 3,331 people died in distracted driving collisions in 2011 -- an increase of almost 65 fatalities from the year prior. In addition, approximately 387,000 people sustained personal injuries in distracted driving accidents in 2011. Consequently, researchers have ...

New drug shows promise in helping people with spinal cord injuries Article provided by Piro, Zinna, Cifelli, Paris & Genitempo, P.C. Visit us at http://www.pirozinnalaw.com According to the Centers for Disease Control and Prevention (CDC), spinal cord injures are a significant problem in the United States. Since the spinal cord is the conduit through which signals between the brain and the body are transmitted, any damage to this vital skeletal formation can cause neurologic impairments that can permanently affect the respiratory, urinary, gastrointestinal or ...

DUI breath tests no good when South Carolina cops give bad instructions Article provided by Christopher A Wellborn PA Visit us at http://www.wellbornlawfirm.com In many drunk driving cases, breath tests results are one of the foundational pieces of evidence relied upon by the prosecution. Yet, just like any other test, the results can be skewed when a breath test is not properly administered. "Blow hard" not correct instruction, thus breath test evidence was thrown out In an order issued in mid March, a judge in Columbia, South Carolina threw out ...

Study shows texting while driving similar to driving drunk Article provided by Harper, Evans, Wade & Netemeyer Visit us at http://www.lawmissouri.com While most Americans understand the risks associated with drinking and driving, the dangers of distracted driving are still being revealed. According to a recent study published in Traffic Injury Prevention, the two types of hazardous behavior may be surprisingly similar. The study revealed that drivers who are distracted by cellphones -- particularly those who text while driving -- are just as dangerous on ...

New hours of service rules for truckers challenged in court Article provided by Rensch & Rensch Law Visit us at http://www.renschandrensch.com The duties of a truck driver require long hours on the road, away from home. In order to ensure the safety of both truck drivers and other motorists on the road, certain regulations are in place that specify -- among other things -- how frequently they must stop and rest. These regulations, referred to as hours of service rules, are meant to ensure truck drivers are alert while behind the wheel. In a few months, new ...

New York strictly enforcing new multiple offender DWI regulations Article provided by Greenspan & Greenspan Visit us at http://www.greenspans-law.com Ever since New York adopted harsher penalties for individuals convicted of multiple driving while intoxicated offenses, the number of people who have lost their licenses has been on the rise. According to data from New York's Department of Motor Vehicles, almost 2,000 applications for driver's licenses have been denied since the rules took effect. The rules provide for different outcomes, depending on the driver's ...

Court limits use of drug-detecting dogs Article provided by Dziedziak & Marcus, P.C. Visit us at http://www.dzmlaw.com Police departments across the country have a large number of officers focused on the investigation of drug crimes that are occurring in their cities. These investigations often lead to many agencies working together to try to catch the individuals responsible for introducing the drugs into the community. If police learn any evidence about the source of the drugs, they will be aggressive in trying to make an arrest. Once an arrest has been ...

Divorce mediation offers numerous benefits Article provided by Antonioni & Antonioni Law Office Visit us at http://www.antonionilaw.com There's no secret about it -- divorce is difficult. It also can be costly. Many people think of the divorce process as being full of conflict and hostility. However, it doesn't have to be that way. Increasingly, divorcing couples are choosing mediation as a way to avoid some of the conflict and expense of adversarial divorce litigation. The divorce mediation process Mediation involves a neutral, third party moderator who ...

NPR series on Social Security Disability reignites disability benefits debate Article provided by The Law Office of Jim McKown Visit us at http://www.indianassdlawyers.com A recent series/expose by National Public Radio (NPR) reporter Chana Joffe-Walt has reignited the ongoing, contentious discussion about what role Social Security Disability (SSD) and other social welfare or disability benefit programs like Supplemental Security Income (SSI) have in American society today. Specifically, the piece focuses on the debate between two polarizing segments: -Those who ...

Survey says many Americans lack sufficient savings for emergencies Article provided by John Christopher Robinson Visit us at http://www.debtfreeky.com According to a recent survey by Bankrate.com, many Americans do not have sufficient savings to cover a financial emergency such as a job loss or unexpected medical expenses. Although experts recommend that people save enough money to cover their regular expenses for at least three months, it appears this advice has fallen on deaf ears for many. During the survey, Bankrate.com asked people whether they have more ...

Six Talk of the Town Award winners were honored for a second time by Talk of the Town News for achieving high levels of customer satisfaction. These businesses have earned the prestigious award again by continually providing outstanding customer service to their patrons, demonstrating their commitment to reaching the highest levels of customer satisfaction. The Talk of the Town Awards, presented by Talk of the Town News and Celebration Media U.S., recognize companies and professionals that provide excellent customer service as reported by their customers through no-cost, ...

Blick Art Materials, a multi-channel retailer with 39 locations, has purchased the stock of Utrecht Art Supplies, a 45-store multi-channel retailer. Both businesses are leading participants in the art supply industry. Robert Buchsbaum, Chief Executive Officer of Blick Art Materials and leader of the newly-combined enterprise, spoke of the transaction "The acquisition of Utrecht gives us a tremendous, well-established brand and greater geographic reach for our brick and mortar channel. We are very excited to welcome Utrecht employees and customers to the Blick team." Madison ...

Kathrin Jansen, Senior Vice President at Pfizer will give a keynote presentation titled "A Novel Multi-antigen Vaccine to Prevent Staphylococcus Aureus Infection and Disease. Can We Beat the Bug at Its Own Game?" at GTC's 11th Vaccines Research & Development: All Things Considered Conference on July 8-10, 2013 in Boston, MA Staphylococcus aureus (SA) causes serious disease in both hospital and community settings and is becoming increasingly resistant to antibiotic treatment. Currently there are no prophylactic vaccines to prevent SA disease, yet the field ...

Lincs Records Inc. has set an April 1 release date for the imminent "Mad Scientist of Sounds" single, "The Rhythm." Mr. Zills (a member of Dungeon Muzik) is an artist adept at creating both timeless house music and new, ingenious sounds. While contributing to several compilation albums, edits, remixes, and four Dungeon Muzik albums, Mr. Zills first single is a summation of years in the life of music -- every trial, tribulation, and triumphs -- it's all here on "The Rhythm." Mr. Zills continues to make his mark, headlining his own shows ...

Interactive Design Solutions is proud to announce the launch of its first annual free website contest! Starting today, Interactive Design Solutions will be accepting submissions for this year's contest. Deadline to enter is August 1, 2013 at 11:59 pm EST. The contest is aimed at any individual, corporation, charity organization, or entity looking for a professional website. One lucky winner will receive a deluxe monthly website design package, a domain name of their choosing, and hosting for one year. The contest is open to residents of the 50 United States and the District ...

On Site Energy announces ADA-compliant cable ramps to protect temporary power cables from pedestrian and vehicular traffic. Designed to help organizations stay in compliance with Americans with Disabilities Act guidelines, the 5-channel ramps are ideal for use in public, commercial, industrial, construction and utility applications, as well as in amusement parks, sporting events and entertainment venues. Organizations that lay down temporary power cables can now easily protect them from damage while enabling safe crossing for vehicle and pedestrian traffic by using cable ...

Joellyn "Joey" Sargent, a strategic marketing expert specializing in business growth announced the launch of HowBizGrows.com for small business. The website contains valuable tips and resources for owners of budding businesses as well as more established firms looking for new paths to profitable growth. "In my work with business owners, I discovered a real demand for affordable tools tailored to the unique needs of small businesses," said Sargent, who is principal of the consulting firm BrandSprout Advisors. "HowBizGrows.com meets that need ...

May's My Pinnacle Network meetings are as follows: My Pinnacle Network - Mansfield, Wednesday, May 1, from 8:30 a.m. - 10 a.m. at 20 Cabot Boulevard, Suite 300, Mansfield, MA 02048. My Pinnacle Network - The Marshfield, Thursday, May 2, from 9 a.m. to 10:30 a.m., 165 Enterprise Drive, Marshfield, MA 02050. My Pinnacle Network - Braintree 1st Tuesday, Tuesday, May 7, from 8:30 a.m. - 10 a.m. at 25 Braintree Hill Office Park, Suite 200, Braintree, MA 02184. My Pinnacle Network - Westborough, Tuesday, May 7, from 8 a.m. - 9:30 a.m. at 1900 West Park Drive, Suite 230, Westborough, ...