Brain cancer is the primary cause of cancer mortality in children. Even in cases when the cancer is cured, young patients suffer from the stress of a treatment that can be harmful to the developing brain. In a search for new target structures that would create more gentle treatments, cancer researchers are systematically analyzing all alterations in the genetic material of these tumors. This is the mission of the PedBrain consortium, which was launched in 2010. Led by Professor Stefan Pfister from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), ...

Before the Big Bang, space-time as we know it did not exist. So how was it born? The process of creating normal space-time from an earlier state dominated by quantum gravity has been studied for years by theorists at the Faculty of Physics, University of Warsaw. Recent analyses suggest a surprising conclusion: not all elementary particles are subject to the same space-time. Several billion years ago, in the era soon after the Big Bang, the Universe was so dense and so hot that elementary particles felt the existence of gravity strongly. For decades, physicists around ...

"Pain begone!" In order to send out this signal, the human body produces tiny messenger molecules that dock to certain receptors. Using traditional biochemical methods, this interaction between the messengers, so-called enkephalins, and opioid receptors is very difficult to study. An interdisciplinary team of biochemists and inorganic chemists at the Ruhr-Universität Bochum (RUB) has now succeeded in identifying the structure of an enkephalin in solution and to track its interaction with the opioid receptor in detail. The analysis provides a new, precise starting point ...

Researchers from North Carolina State University have developed three-dimensional (3-D) printing technology and techniques to create free-standing structures made of liquid metal at room temperature. "It's difficult to create structures out of liquids, because liquids want to bead up. But we've found that a liquid metal alloy of gallium and indium reacts to the oxygen in the air at room temperature to form a 'skin' that allows the liquid metal structures to retain their shapes," says Dr. Michael Dickey, an assistant professor of chemical and biomolecular engineering at ...

This news release is available in German. An unusual posthumous honour for physicist Max Planck: Biologists in Tübingen working with Ralf J. Sommer have named a newly discovered nematode after the German Nobel laureate. Pristionchus maxplancki is thus the first species to carry the name of the scientist, who died in 1947. The discovery from the Far East is assisting the researchers of the Max Planck Institute for Developmental Biology to attain new insights and knowledge about the many interdependencies between evolution, genetics, and ecology. When Japanese biologist ...

CHICAGO (July 9, 2013) – After a 2011 outbreak of P. aeruginosa, investigators at Beaumont Health System near Detroit, Michigan determined contaminated ultrasound gel was the source of bacteria causing the healthcare-associated infection. The findings emphasize the need for increased scrutiny of contaminated medical products. This study is published in the August issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. "Ultrasound is a critical healthcare tool used every day in both diagnostic and interventional ...

LA JOLLA, Calif., July 8 2013 – Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which are used to inhibit gene expression. The drugs, in essence, mimic a natural process called RNA interference. In a new paper appearing today online in the journal, ACS Medicinal Chemistry Letters, researchers at Sanford-Burnham Medical Research Institute have developed nanoparticles that appear to solve a big challenge ...

Infrared imagery from the AIRS instrument aboard NASA's Aqua satellite revealed that Erick, now a tropical depression has reduced in strength and size and continues to weaken. The Atmospheric Infrared Sounder or AIRS instrument on NASA's Aqua satellite flew over Tropical Depression Erick late on July 8 and captured an infrared image that revealed Erick was quickly weakening. The AIRS image taken on July 8 at 4:17 p.m. EDT showed a small area of clouds and circulation near the southern tip of Mexico's Baja California peninsula. The strongest thunderstorms with cloud top ...

Scientists discovered a tiny new species of catfish in the waters of Rio Rio Paraíba do Sul basin, Brazil. The new species Pareiorhina hyptiorhachis belongs to a genus of armored catfishes native to South America where and found only in Brazil. These peculiar fish get their name from their strange elongated mouth barbels that remind of cat's whiskers. The new species is distinguished from others species of the genus by the presence of a conspicuous ridge on the trunk posterior to the dorsal fin (postdorsal ridge). The description of the diminutive new species was published ...

For decades, women between the ages of 21 and 69 were advised to get annual screening exams for cervical cancer. In 2009, however, accumulating scientific evidence led major guideline groups to agree on a new recommendation that women be screened less frequently: every three years rather than annually. Despite the revised guidelines, about half of the obstetrician-gynecologists surveyed in a recent study said they continue to provide annual exams – an outdated practice that may be more harmful than helpful, said Drs. Russell Harris and Stacey Sheridan of the Cecil G. ...

New Orleans, LA – A study conducted by Dr. James Diaz, Professor of Public Health and Preventive Medicine and Program Director of the Environmental/Occupational Health Sciences Program at the LSU Health Sciences Center New Orleans School of Public Health, analyzed cases of a parasitic lung infection and found new modes of transmission and associated behaviors, identifying new groups of people at risk. Dr. Diaz hopes to raise the index of suspicion among medical professionals so non-traditional patients and those not exhibiting all symptoms but who are at risk can be diagnosed ...

An intensive lifestyle intervention, proven to help people lose weight to prevent diabetes, also works in primary care when delivered over the telephone to obese patients with metabolic syndrome. Group telephone sessions appear to be particularly effective for greater weight loss, according to a new study by Drs. Paula Trief and Ruth Weinstock from SUNY Upstate Medical University in Syracuse, New York, and colleagues. Their work¹ appears online in the Journal of General Internal Medicine², published by Springer. Metabolic syndrome affects a third of US adults and is associated ...

CHICAGO -- Antibiotic-resistant superbugs like carbapenem-resistant Enterobacteriaceae (CRE) present a challenge to healthcare professionals as patients move from different care settings and facilities, unknowingly spreading healthcare-associated infections. In a new study, researchers screened all patients for CRE at admission to a long-term acute care hospital (LTACH). They found patients colonized with CRE coming into the LTACH from hospitals, but they also found transmission occurring among patients in the LTACH. LTACHs provide similar care as hospitals but focus on ...

Before scientists and engineers can realize the dream of using stem cells to create replacements for worn out organs and battle damaged body parts, they'll have to develop ways to grow complex three-dimensional structures in large volumes and at costs that won't bankrupt health care systems. Researchers are now reporting advances in these areas by using gelatin-based microparticles to deliver growth factors to specific areas of embryoid bodies, aggregates of differentiating stem cells. The localized delivery technique provides spatial control of cell differentiation within ...

As modern Egypt searches for a new leader, Israeli archaeologists have found evidence of an ancient Egyptian leader in northern Israel. At a site in Tel Hazor National Park, north of the Sea of Galilee, archeologists from the Hebrew University of Jerusalem have unearthed part of a unique Sphinx belonging to one of the ancient pyramid-building pharaohs. The Hazor Excavations are headed by Prof. Amnon Ben-Tor, the Yigael Yadin Professor in the Archaeology of Eretz Israel at the Hebrew University's Institute of Archaeology, and Dr. Sharon Zuckerman, a lecturer at the ...

Many parents have a difficult time persuading their preschool-aged children to try vegetables, let alone eat them regularly. Food and nutrition researchers have found that by offering a dip flavored with spices, children were more likely to try vegetables -- including those they had previously rejected. "Less than 10 percent of four-to-eight-year-olds consume the USDA (U.S. Department of Agriculture) recommended daily servings of vegetables," said Jennifer S. Savage, associate director of the Center for Childhood Obesity Research at Penn State. "Even more striking is ...

WHAT: The emergence of a novel H7N9 avian influenza virus in humans in China has raised questions about its pandemic potential as well as that of related influenza viruses. In a commentary published online today, scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, address these questions by evaluating past outbreaks of H7 subtype influenza viruses among mammals and birds and comparing H7 viruses with other avian influenza viruses and strains. In recent decades, the scientists write, avian H7 viruses ...

Sophia Antipolis -- A resurgence in cardiovascular R&D is urgently needed to curb a new epidemic of cardiovascular diseases, according to leading cardiologists and industry representatives in the Cardiovascular Round Table (CRT). The CRT is an independent forum established by the European Society of Cardiology (ESC) and comprised of cardiologists and representatives of the pharmaceutical and medical device industries. The group's views are outlined in "Championing Cardiovascular Health Innovation in Europe", published in European Heart Journal.(1) Professor Michel Komajda ...

Spontaneous survivors of acetaminophen overdose have significantly lower overall health compared to survivors or transplant recipients following acute liver failure caused by non-drug induced liver injury according to a new study published online in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Findings show that acetaminophen overdose survivors report more days of impaired mental and physical health, and activity limitations due to poor health, pain, anxiety and depression. ...

Toronto – If achieving a work/life balance wasn't hard enough, researchers say many of us are juggling a third factor: school. That creates conflicts, say Bonnie Cheng, a PhD candidate at the University of Toronto's Rotman School of Management, and Julie McCarthy, an associate professor at the Rotman School and the University of Toronto Scarborough, often resulting in dissatisfaction in the area that caused that conflict. For example, skipping a family function to stay late at work can lead to less satisfaction with work. But avoidance techniques can help, their most ...

HOUSTON – (July 9, 2013) – A Rice University laboratory pioneering memory devices that use cheap, plentiful silicon oxide to store data has pushed them a step further with chips that show the technology's practicality. The team led by Rice chemist James Tour has built a 1-kilobit rewritable silicon oxide device with diodes that eliminate data-corrupting crosstalk. A paper on the new work appears this week in the journal Advanced Materials. With gigabytes of flash memory becoming steadily cheaper, a 1k nonvolatile memory unit has little practical use. But as a proof ...

Amyotrophic Lateral Sclerosis (ALS) is a devastating motor neuron disease that rapidly atrophies the muscles, leading to complete paralysis. Despite its high profile — established when it afflicted the New York Yankees' Lou Gehrig — ALS remains a disease that scientists are unable to predict, prevent, or cure. Although several genetic ALS mutations have been identified, they only apply to a small number of cases. The ongoing challenge is to identify the mechanisms behind the non-genetic form of the disease and draw useful comparisons with the genetic forms. Now, using ...

Fast-accumulating data seem to indicate that our close cousins, the Neandertals, were much more similar to us than imagined even a decade ago. But did they have anything like modern speech and language? And if so, what are the implications for understanding present-day linguistic diversity? The MPI for Psycholinguistics researchers Dan Dediu and Stephen C. Levinson argue in their paper in Frontiers in Language Sciences that modern language and speech can be traced back to the last common ancestor we shared with the Neandertals roughly half a million years ago. The Neandertals ...

Using nanostructured glass, scientists at the University of Southampton have, for the first time, experimentally demonstrated the recording and retrieval processes of five dimensional digital data by femtosecond laser writing. The storage allows unprecedented parameters including 360 TB/disc data capacity, thermal stability up to 1000°C and practically unlimited lifetime. Coined as the 'Superman' memory crystal, as the glass memory has been compared to the "memory crystals" used in the Superman films, the data is recorded via self-assembled nanostructures created in ...

New Rochelle, NY -- Next-generation hydrogels can form synthetic scaffolds to support the formation of replacement tissues and organs in the emerging area of regenerative medicine. Embedding peptides into the hydrogels stimulates the growth of essential microvascular networks to ensure a good blood supply. Novel, cutting-edge technology in which hydrogels functionalized with laminin-derived peptides were transplanted in a mouse cornea and were shown to support cell growth and blood vessel formation is described in an article in BioResearch Open Access, a peer-reviewed open ...