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Nano-machines for 'bionic proteins'

Nano-machines for bionic proteins
2013-02-15
This press release is available in German. Physicists of the University of Vienna together with researchers from the University of Natural Resources and Life Sciences Vienna developed nano-machines which recreate principal activities of proteins. They present the first versatile and modular example of a fully artificial protein-mimetic model system, thanks to the Vienna Scientific Cluster (VSC), a high performance computing infrastructure. These "bionic proteins" could play an important role in innovating pharmaceutical research. The results have now been published in ...

Study finds possible link between diabetes and increased risk of heart attack death

2013-02-15
Having diabetes doubles a person's risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart enzyme, which leads to death of pacemaker cells in the heart, abnormal heart rhythm, and increased risk of sudden death in diabetic mice following a heart attack. "Many studies have shown that patients with diabetes are at especially high risk for dying from a myocardial infarction (heart attack). Our study provides new evidence that this excess ...

Wild plants are infected with many viruses and still thrive

2013-02-15
UNIVERSITY PARK, PA. -- Researchers have studied viruses as agents of disease in humans, domestic animals and plants, but a study of plant viruses in the wild may point to a more cooperative, benevolent role of the microbe, according to a Penn State virologist. "Most of these wild plants have viruses," said Marilyn Roossinck, professor of plant pathology and environmental microbiology and biology, who has examined more than 7,000 individual plants for viruses. "But they don't have any of the symptoms that we usually see in crop plants with viruses." Most of the viruses ...

Technique that removes additional toxins prolongs dialysis patients' lives

2013-02-15
Highlights A technique that removes additional toxins during dialysis decreased kidney failure patients' risk of dying from any cause by 30% over three years. The technique also reduced patients' risk of dying from heart-related causes or infections. 15% to 25% of dialysis patients die annually. Washington, DC (February 14, 2013) — A technique that removes additional toxins during dialysis may prolong kidney failure patients' lives, according to a clinical trial appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). In light of ...

Accelerated protons confirm origin of cosmic rays

2013-02-15
We are constantly being bombarded by speedy, energetic, and yet unassuming, particles called cosmic rays. These charged particles (mostly protons), continuously assail the Earth from outer space. There is general consensus among scientists that supernova remnants (the leftovers of a supernova explosion) are the sources of cosmic rays, but the final proof has been elusive since cosmic rays are deflected on their way from the source to Earth. A new study offers conclusive evidence that cosmic ray protons within our galaxy are accelerated in the shock waves produced by ...

Fish become bolder and more gluttonous from drug residue

Fish become bolder and more gluttonous from drug residue
2013-02-15
Anxiety-moderating drugs that reach waterways via wastewater create fearless and asocial fish that eat more quickly than normal. These behavioral changes can have serious ecological consequences. This is shown by Umeå University researchers in the prestigious journal Science. Many drugs leave our bodies unaffected, and residues from them are therefore found in wastewater. Low concentrations of drugs are often found downstream from sewage treatment plants. Today we test how dangerous drugs are to humans, but our knowledge of the environmental impacts of drugs is limited. ...

Mood-modifying drugs for humans also alter fish behavior

Mood-modifying drugs for humans also alter fish behavior
2013-02-15
Pharmaceutical drugs that end up in the world's waterways after being excreted, flushed and treated at wastewater treatment plants may lead to unexpected ecological impacts, according to a new study of wild European perch. Tomas Brodin and colleagues from Umeå University in Sweden discovered that the fish ate faster, became bolder and acted less social after being subjected to an anxiety-moderating drug, known as Oxazepam. The psychiatric drug is used to treat anxiety in humans. But, Oxazepam residues often wind up in natural aquatic systems, downstream from sewage treatment ...

Proof: Cosmic rays come from exploding stars

Proof: Cosmic rays come from exploding stars
2013-02-15
Menlo Park, Calif. — A new study confirms what scientists have long suspected: Cosmic rays – energetic particles that pelt Earth from all directions – are born in the violent aftermath of supernovas, exploding stars throughout the galaxy. A research team led by scientists at the Kavli Institute for Particle Astrophysics and Cosmology at the Department of Energy's (DOE) SLAC National Accelerator Laboratory sifted through four years of data from NASA's Fermi Gamma-ray Space Telescope to find the first unambiguous evidence of how cosmic rays are born. Reporting in the ...

Rapid changes in the Arctic ecosystem during ice minimum in summer 2012

2013-02-15
This press release is available in German. Bremerhaven, 14 February 2013. Huge quantities of algae are growing on the underside of sea ice in the Central Arctic: in 2012 the ice algae Melosira arctica was responsible for almost half the primary production in this area. When the ice melts, as was the case during the ice minimum in 2012, these algae sink rapidly to the bottom of the sea at a depth of several thousands of metres. Deep sea animals such as sea cucumbers and brittle stars feed on the algae, and bacteria metabolise what's left, consuming the oxygen in the ...

Study of insomnia finds a new predictor for suicidal thoughts

2013-02-15
DARIEN, IL – A new study confirms a link between insomnia and thoughts of suicide and suggests that this relationship is mediated by dysfunctional beliefs and attitudes about sleep as well as nightmares. The study suggests that the targeted assessment and treatment of specific sleep problems may reduce the risk of suicide in people with depressive symptoms. "Insomnia and nightmares, which are often confused and go hand-in-hand, are known risk factors for suicide but just how they contribute was unknown," said Dr. W. Vaughn McCall, the study's lead author and chair of ...

Trolls win: Rude blog comments dim the allure of science online

2013-02-15
BOSTON – The trolls are winning. Pick a story about some aspect of science, any story, scroll down to the blog comments and let the bashing begin: "Wonder how much taxpayer cash went into this 'deep' study?" "I think you can take all these studies by pointy headed scientists, 99 percent of whom are socialists and communists, and stick them where the sun don't shine." "Yawn. Climate change myth wackos at it again." "This article is 100 percent propaganda crapola." "Speaking of dolts, if you were around in the 70s, when they also had scientists, the big talk ...

The role of radical prostatectomy in patients with prostate cancer

2013-02-15
Even in the presence of screening, there is benefit to radical prostatectomy (RP) in prostate cancer patients, however, the benefit is limited to a subgroup of patients and can take years to become evident according to a study published February 14 in the Journal of the National Cancer Institute. The Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) trial identified that RP lowered prostate cancer deaths with a statistically significant absolute mortality difference (AMD) between RP and watchful waiting (WW) of 6.1%. The Prostate Cancer Intervention Versus Observation ...

The human pathogen Streptococcus pneumonia shields foreign DNA derived from other bacteria to promote genetic diversity and vaccine evasion

2013-02-15
FINANCIAL DISCLOSURE: CJ was funded by a grant from the Agence Nationale de la Recherche (projet n_ BLAN06-3_141806). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. COMPETING INTEREST: The authors have declared that no competing interests exist. PLEASE ADD THIS LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://dx.plos.org/10.1371/journal.ppat.1003178 (link will go live upon embargo lift) CITATION: Johnston C, Martin B, Granadel C, Polard P, Claverys J-P (2013) Programmed ...

Study shows alcohol consumption is a leading preventable cause of cancer death in the US

2013-02-15
(Boston) – Researchers from the Boston University School of Medicine (BUSM) and Boston University School of Public Health (BUSPH) have shown that alcohol is a major contributor to cancer deaths and years of potential life lost. These findings, published in the April 2013 issue of the American Journal of Public Health, also show that reducing alcohol consumption is an important cancer prevention strategy as alcohol is a known carcinogen even when consumed in small quantities. Previous studies consistently have shown that alcohol consumption is a significant risk factor ...

Johns Hopkins researchers create new air sacs in mouse model of emphysema using novel growth factor

2013-02-15
In a study of mice, researchers at Johns Hopkins have identified a new molecular pathway involved in the growth of tiny air sacs called alveoli that are crucial for breathing. The scientists say their experiments may lead to the first successful treatments to regrow the air sacs in people who suffer from diseases such as emphysema in which the air sacs have been destroyed by years of smoking. The work may also suggest new therapy for premature infants born before their lungs are fully developed. "One of the most daunting challenges we face as physicians is helping patients ...

U of M researchers find that doula care for low-income women could save taxpayers money

2013-02-15
MINNEAPOLIS / ST. PAUL (EMBARGOED UNTIL February 14, 2013) – New research from the University of Minnesota's School of Public Health has found lower cesarean birth rates among Medicaid beneficiaries with access to support from a birth doula than among Medicaid patients nationally. A doula is not a medical provider, but is a trained, experienced professional person who can provide information, physical assistance and support to a woman during childbirth. The research indicates that policy changes to provide Medicaid coverage for birth doulas may actually decrease costs ...

X-ray laser sees photosynthesis in action

X-ray laser sees photosynthesis in action
2013-02-15
Opening a new window on the way plants generate the oxygen we breathe, researchers used an X-ray laser at the Department of Energy's (DOE) SLAC National Accelerator Laboratory to simultaneously look at the structure and chemical behavior of a natural catalyst involved in photosynthesis for the first time. The work, made possible by the ultrafast, ultrabright X-ray pulses at SLAC's Linac Coherent Light Source (LCLS), is a breakthrough in studying atomic-scale transformations in photosynthesis and other biological and industrial processes that depend on catalysts, which ...

Combo of Avastin, second drug shows promise fighting brain cancer, Mayo Clinic finds

2013-02-15
JACKSONVILLE, Fla. — The drug bevacizumab, also known by the trade name Avastin, shrinks tumors briefly in patients with an aggressive brain cancer known as glioblastoma multiforme, but then they often grow again and spread throughout the brain for reasons no one previously has understood. Now, Mayo Clinic researchers have found out why this happens. They have also discovered that pairing Avastin with another cancer drug, dasatinib, can stop that lethal spread. Dasatinib is approved for use in several blood cancers. The findings, based on an animal study, are detailed ...

Scientists develop improved fire management tools for Africa's savannas

2013-02-15
DAKAR, SENEGAL (15 February 2013)—Scientists at the Nairobi-based World Agroforestry Centre (ICRAF) and partners have developed specialized graphs that map out fire behavior, known as nomographs, for landscape managers in Africa's savannas. The study, published in the February issue of the Journal of Arid Environments, pinpoints the optimal conditions for setting early-season prescribed fires—a process that when executed and timed properly, reduces the risk and impact of late dry season bushfires in increasingly fragile ecosystems, both of which are exacerbated by climate ...

Humans and chimps share genetic strategy in battle against pathogens

2013-02-15
A genome-wide analysis searching for evidence of long-lived balancing selection—where the evolutionary process acts not to select the single best adaptation but to maintain genetic variation in a population—has uncovered at least six regions of the genome where humans and chimpanzees share the same combination of genetic variants. The finding, to be published Feb. 14 in the journal Science, suggests that in these regions, human genetic variation dates back to a common ancestor with chimpanzees millions of years ago, before the species split. It also highlights the importance ...

Smoking bans linked with 'successive reductions' in preterm birth

2013-02-15
The study supports the notion that smoking bans have public health benefits from early life. It is well established that smoking during pregnancy impairs the growth of an unborn child and shortens gestation. Exposure to second-hand smoke has also been found to affect birth outcomes, yet little is known about the impact of recent smoke-free legislation on birth weight and preterm birth. So a team of researchers, lead by Dr Tim Nawrot from Hasselt University, investigated whether recent smoking bans in Belgium were followed by changes in preterm delivery. In Belgium, ...

Study finds strong link between income inequality and readmission risk, but not mortality

2013-02-15
The authors estimate nearly 40,000 extra admissions to hospital as a result of income inequality over the three year study period. Income inequality is associated with a variety of adverse health outcomes, including higher infant mortality, reduced life expectancy, and poorer self-reported health. But little is known about the possible link between income inequality and outcome after admission to acute care hospitals. So a team of US researchers examined the association between income inequality and risk of death and readmission within 30 days of discharge from hospital. ...

Tough, light and strong: Lessons from nature could lead to the creation of new materials

Tough, light and strong: Lessons from nature could lead to the creation of new materials
2013-02-15
In a sweeping review of the field of bio-inspired engineering and biomimicry in the Feb. 15 issue of the journal Science, two engineers at the University of California, San Diego, identify three characteristics of biological materials that they believe engineers would do well to emulate in man-made materials: light weight, toughness and strength. Joanna McKittrick and Marc Meyers, from the materials science program at the Jacobs School of Engineering at UC San Diego, examine the three characteristics in a wide range of materials, from spider silk, to lobster and abalone ...

Clues to the mysterious origin of cosmic rays

Clues to the mysterious origin of cosmic rays
2013-02-15
In the year 1006 a new star was seen in the southern skies and widely recorded around the world. It was many times brighter than the planet Venus and may even have rivaled the brightness of the Moon. It was so bright at maximum that it cast shadows and it was visible during the day. More recently astronomers have identified the site of this supernova and named it SN 1006. They have also found a glowing and expanding ring of material in the southern constellation of Lupus (The Wolf) that constitutes the remains of the vast explosion. It has long been suspected that such ...

Slithering towards extinction

2013-02-15
NINETEEN PERCENT of the world's reptiles are estimated to be threatened with extinction, states a paper published today by the Zoological Society of London (ZSL) in conjunction with experts from the IUCN Species Survival Commission (SSC). The study, printed in the journal of Biological Conservation, is the first of its kind summarising the global conservation status of reptiles. More than 200 world renowned experts assessed the extinction risk of 1,500 randomly selected reptiles from across the globe. Out of the estimated 19% of reptiles threatened with extinction, ...
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