New Rochelle, NY, April 10, 2013—New classes of drugs that can silence specific genes, such as small interfering RNAs (siRNAs), offer great therapeutic potential. But the specific delivery of siRNAs to target cells to exert their effects remains a significant challenge. A novel nanoparticle-based approach that enables more efficient delivery of siRNA drugs is presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers (http://www.liebertpub.com). The article is available on the Nucleic Acid Therapeutics website (http://www.liebertpub.com/nat). Compared ...

It may seem counter-intuitive to take health advice from a marketing professor, but when it comes to analyzing consumer data and its relationship to managing health issues such as diabetes, one University of Alberta researcher may have the right prescription. In a paper recently published in the Journal of Marketing, Alberta School of Business professor Yu Ma uncovered information that has implications for health-care professionals, marketers and consumers alike. He says the data on consumer spending contain streams of information showing that decisions consumers make ...

Topological insulators (TIs) are an exciting new type of material that on their surface carry electric current, but within their bulk, act as insulators. Since the discovery of TIs about a decade ago, their unique characteristics (which point to potential applications in quantum computing) have been explored theoretically, and in the last five years, experimentally. But where in theory, the bulk of TIs carry no current, in the laboratory, impurities and disorder in real materials means the bulk is, in fact, conductive. This has proven an obstacle to experimentation with ...

CAMBRIDGE, MA -- Many factors — including climate change, overfishing or loss of food supply — can push a wild animal population to the brink of collapse. Ecologists have long sought ways to measure the risk of such a collapse, which could help wildlife and fishery managers take steps to protect endangered populations. Last year, MIT physicists demonstrated that they could measure a population's risk of collapse by monitoring how fast it recovers from small disturbances, such as a food shortage or overcrowding. However, this strategy would likely require many years of ...

Functional loss of limb control in individuals with spinal cord injury or stroke can be caused by interruption of the neural pathways between brain and spinal cord, although the neural circuits located above and below the lesion remain functional. An artificial neural connection that bridges the lost pathway and connects brain to spinal circuits has potential to ameliorate the functional loss. Yukio Nishimura, Associate Professor of the National Institute for Physiological Sciences, Japan, and Eberhard Fetz, Professor and Steve Perlmuter, Research Associate Professor at ...

A novel study shows women who undergo surgical treatment for endometriosis have a lower risk of developing ovarian cancer. According to results published in Acta Obstetricia et Gynecologica Scandinavica, a journal of the Nordic Federation of Societies of Obstetrics and Gynecology, hormonal treatments for endometriosis did not lower ovarian cancer risk. Endometriosis is a common, and often painful, gynecological disease where tissue normally found inside the uterus, grows elsewhere in the body. According to the World Health Organization this estrogen-dependent disease ...

A comprehensive marine biodiversity observation network could be established with modest funding within 5 years, according to an expert assessment published in the May 2013 issue of BioScience. Such a network would fill major gaps in scientists' understanding of the global distribution of marine organisms, which are under unprecedented threat from climate change, pollution, habitat destruction, and overfishing. The network would help resolve conflicts over ocean management and identify threats such as invasions by exotic species before they became obvious, according to ...

GAINESVILLE, Fla. --- With ocean life facing unprecedented threat from climate change, overfishing, pollution, invasive species and habitat destruction, a University of Florida researcher is helping coordinate national efforts to monitor marine biodiversity. Humans depend on the ocean for food, medicine, transportation and recreation, yet little is known about how these vast ecosystems spanning 70 percent of the Earth's surface are functioning and changing. Following a workshop sponsored by U.S. federal agencies in 2010, researchers at eight institutions have proposed ...

Being the first to file for divorce has several advantages Article provided by Zollie C. Steakley, PLLC Visit us at http://www.zolliesteakley.com Divorce can be a difficult and emotional process. Dealing with all of the aspects of a divorce can be even more difficult when a spouse's decision to divorce is unexpected. However, many times both spouses know they are heading toward divorce. If this is the case, there are numerous legal and financial benefits to being the first to file a divorcepetition. Filing first provides an opportunity to get organized and ...

Those accused of domestic violence face serious penalties Article provided by Law Office of Edward E. DeWerff Visit us at http://www.dewerfflaw.com Without a doubt, domestic violence is a serious issue for everyone involved; however, it can be a life-changing event for an individual who gets falsely accused of such acts. The term "domestic violence" can cover physical harm that is inflicted on any member of a household by another member of that same household. It is sometimes called spousal abuse as well, and even though murder and rape can be considered ...

Missouri criminal law: driving in a drugged condition Article provided by Rosenblum Schwartz Rogers & Glass, P.C. Visit us at http://www.rsrglaw.com/ In January 2013, St. Louis County, Mo., Police stopped a 29-year-old Dittmer man one evening while he was driving near Grant's Farm, south of St. Louis, according to the Sunset Hills-Crestwood Patch. In March, the defendant was charged with driving under the influence of illegal drugs, specifically opiates, amphetamine and methamphetamine, reportedly as evidenced by blood test results. In Missouri, anyone who ...

Washington Supreme Court dismisses custodial interference charges Article provided by Law Offices of Susan Millican O'Brian & Associates, P.S. Visit us at http://www.smobrian.com The Washington Supreme Court recently dismissed a case against a father charged with first degree custodial interference. The <a target="_blank" href="http://www.courts.wa.gov/index.cfm?fa=controller.managefiles&filePath=Opinions&fileName=858608.pdf]case[/url] involves a father who took his four-year-old daughter from Washington to Mexico in violation of the ...

Teen driver fatality rate climbing in 2013 Article provided by Gainsburgh, Benjamin, David, Meunier & Warshauer, L.L.C. Visit us at http://www.gainsburghbenjamin.com Though 2013 is but a few months old, there have already been a spate of high-profile, fatal accidents involving teen drivers and their passengers. A recent crash outside Chicago killed four teens when the young driver hit a patch of ice, slid through a guardrail and ended up in a nearby creek. A similar incident in Ohio resulted in another six deaths. The Governors' Highway Safety Association ...

Starting a business in Indiana? Choose your formation carefully Article provided by Lewis & Kappes Visit us at http://www.lewis-kappes.com Starting a new business is a huge endeavor. If you're about to head down this path, you've probably spent a lot of time worrying about things like creating a business plan, lining up investors, finding customers and hiring staff. However, in the midst of all of these big issues, it is important not to overlook a basic -- but crucial -- business planning decision: what structure should your business take? Assuming you are ...

Proposed change to Tennessee DUI laws Article provided by T. Bailey Law Office Visit us at http://www.tbaileylawoffice.com/ The sponsors of a new bill being proposed in Tennessee hope the measure saves lives and makes the roads safer. Proposed changes to the penalties for being convicted of driving while under the influence reflect how seriously the lawmakers take the safety and well-being of the state's residents. Change in Tennessee law The legal drinking limit in Tennessee is currently set at 0.08 percent. Currently, the law dictates that those who have ...

What factors are common to wrongful criminal convictions? Article provided by Feeley & Sayegh LLC Attorneys At Law Visit us at http://www.jjslawoffice.com It sounds like a bad dream: a guilty sentence given to an innocent person. However, it does happen. If components of a criminal case are overlooked, this may leave room for error. With this in mind, it is extremely important to decipher what factors, specifically lead to mistakes in a criminal investigation and trial. According to research from the Washington Institute for Public and International Affairs ...

"Barefoot Bandit" faces new charges after two-year crime spree Article provided by Jeff Staples, Attorney at Law Visit us at http://www.jeffstapleslaw.com/ Before his arrest in 2010, Colton Harris-Moore, better known as the "Barefoot Bandit," held a gun to his head and threatening to take his own life rather than be brought in to face the charges against him. Currently serving a seven-year prison sentence six-and-a-half year prison sentence on a variety of federal charges, Harris-Moore, like most people facing criminal charges, feared going to ...

New bill proposes legalizing sobriety checkpoints in Wisconsin Article provided by Buting, Williams & Stilling, S.C. Visit us at http://www.buting.com Every American is guaranteed certain fundamental rights by the Constitution. Among them is the Fourth Amendment right to be free from unreasonable searches and seizures. In the context of a traffic stop, under normal circumstances, this means that a law enforcement officer needs reasonable suspicion to pull over a car. Would a reasonable person, based on specific and articulable facts, suspect that an offense ...

Older Americans filing for bankruptcy as financial pressures mount Article provided by Thrush & Rohr LLC Visit us at http://www.thrushandrohr.com The recent economic collapse affected older Americans disproportionately. Many saw the value of their estates dwindle as investments declined in value and little or no income came in from interest on savings. According to a recent report by the AARP's Public Policy Institute, more Americans over the age of 60 are struggling with debt. This has pushed many to consider bankruptcy. The institute's research found that ...

Covering flip books, apps, online newsstands and blog-style magazines, you will learn: magazine business fundamentals, how to create an editorial philosophy, how to build an editorial calendar, places where content and images can be found, the different ways a digital magazine can be monetized and the tools that will be necessary for producing a digital publication. Additional topics include: how to effectively use social media to connect with your audience, considerations for setting up a website or blog and search engine optimization techniques that can help to improve ...

Minka first entered the ceiling fan market as a decorative light manufacturer. As the company grew, so did Minka's concepts. Eventually Minka Aire ceiling fans were developed to offer elegant designs, energy efficiency, maximum comfort, and versatile decor options for any room in the house. Today Minka Aire has over thirty styles and is known as being on the vanguard of design that uniquely combines form and function. Minka Aire ceiling fans are innovative, fun, and flashy. From the ultra-modern to the traditional, Minka Aire is sure to have a style that fits both your ...

Gregory Bonfiglio from Proteus Venture Partners, will give a presentation on "Funding for Regenerative Medicine Technologies: Opportunities And Challenges" at the Stem Cell Summit 2013 (Apr 29-30, 2013 in Boston, MA) Greg Bonfiglio is a Managing Partner of Proteus Ventures and Chair of the Centre for Commercialization of Regenerative Medicine (CCRM). He will explore the significant opportunities and challenges in commercializing stem cell research and its applications to treat disease from a technical, financial, intellectual property and reimbursement perspective ...

Elastix, the largest open source software solution for unified communications in Latin America, announced today that Grandstream Networks, the leading manufacturer of IP voice/video telephony and video surveillance solutions, is an official sponsor of Elastix worldwide training centers and training courses. Grandstream's sponsorship covers two product categories: IP Multimedia Phones and FXO Gateways. Elastix Training Centers located worldwide will be equipped with the Skype-certified GXV3140 IP Multimedia Phone and GXW4104 FXO Gateways for use in educating and certifying ...

NY entrepreneur and gentleman about town Alan "Action" Schneider unashamedly embraces the term Sugar Daddy. "With the economy in the condition it is in, women are gravitating to the traditional relationship where the man is the provider," says Mr. Schneider. "Many women appreciate men who extend to them mentorship, chivalry, attention, and financial and emotional assistance. Throughout history and up to the current day, these relationships simply work. Despite the dim view that some may have of sugar daddy/sugar baby relationships, their numbers ...

has carved a niche in the small business sector and launched a dedicated Small Business Division to specifically cater to this fast growing client base. In addition, VoiceNation recently revamped their answering service for small businesses webpage to be more user-friendly for business owners. VoiceNation's Small Business Answering Service division serves a wide variety of small businesses ranging from real estate firms, legal firms, medical and dental practices to general contractors, plumbing/HVAC, restaurants, property management firms, religious organizations and ...