Arnhem, 11 March 2013- Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients. The study, which won the third prize for best abstract in oncology at the 28th European Association of Urology Congress held in Milan, Italy from 15 to 19 March, showed the promising benefit of this combination therapy in patients who are chemotherapy-naive or those not yet exposed to specific antigens. "Results of our randomized prospective study suggest that ...

BUFFALO, N.Y. – The first controlled clinical trial to test the safety and efficacy of interventional endovascular therapy on the symptoms and progression of multiple sclerosis has found that the intervention, sometimes called the "liberation treatment," which has attracted intense interest in the global MS community, does not improve patient outcomes. In a few cases, the treatment made symptoms worse. University at Buffalo researchers will present their results in an "Emerging Science" poster session March 20 at the annual American Academy of Neurology meeting in San ...

Scientists at Johannes Gutenberg University Mainz (JGU) and the Max Planck Institute for Polymer Research (MPI-P) in Germany have created a new synthetic hybrid material with a mineral content of almost 90 percent, yet extremely flexible. They imitated the structural elements found in most sea sponges and recreated the sponge spicules using the natural mineral calcium carbonate and a protein of the sponge. Natural minerals are usually very hard and prickly, as fragile as porcelain. Amazingly, the synthetic spicules are superior to their natural counterparts in terms of ...

SAN DIEGO - A series of studies demonstrate improved detection of the second most common form of dementia, providing diagnostic specificity that clears the way for refined clinical trials testing targeted treatments. The new research is being presented by experts from the Perelman School of Medicine at the University of Pennsylvania at the American Academy of Neurology's 65th Annual Meeting in San Diego March 16-23, 2013. Frontotemporal degeneration, the most common dementia in people under 60, can be hereditary or sporadic in nature and caused by one of two different ...

SAN DIEGO - Telestroke programs substantially improve access to life-saving stroke care, extending coverage to less populated areas in an effort to reduce disparities in stroke care access. A new study by researchers from the Perelman School of Medicine at the University of Pennsylvania, being presented at the American Academy of Neurology's 65th Annual Meeting in San Diego March 16-23, 2013, found that telemedicine programs in Oregon pushed stroke coverage into previously uncovered, less populated areas and expanded coverage by approximately 40 percent. "Telestroke ...

EAST LANSING, Mich. --- Scientists have discovered a molecular process in the brain triggered by cocaine use that could provide a target for treatments to prevent or reverse addiction to the drug. Reporting in the Journal of Neuroscience, Michigan State University neuroscientist A.J. Robison and colleagues say cocaine alters the nucleus accumbens, the brain's pleasure center that responds to stimuli such as food, sex and drugs. "Understanding what happens molecularly to this brain region during long-term exposure to drugs might give us insight into how addiction occurs," ...

TALLAHASSEE, Fla. — Oil from the 2010 Deepwater Horizon spill acted as a catalyst for plankton and other surface materials to clump together and fall to the sea floor in a massive sedimentation event that researchers are calling a "dirty blizzard." Jeff Chanton, the John Widmer Winchester Professor of Oceanography in the Department of Earth, Ocean and Atmospheric Science at Florida State University, is one of the members of the Deep-C Consortium who presented the dirty blizzard hypothesis at a recent conference in New Orleans that focused on the effects of the oil spill ...

SAN DIEGO – Injecting synthetic tau fibrils into animal models induces Alzheimer's-like tau tangles and imitates the spread of tau pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania being presented at the American Academy of Neurology's 65th Annual Meeting in San Diego March 16-23, 2013. This Alzheimer's research, along with additional Parkinson's research from Penn and beyond, further demonstrates the cell-to-cell transmission of neurodegenerative proteins. John Q. Trojanowski, MD, PhD, co-director of the Center for ...

West Orange, NJ. March 15, 2013. Kessler Foundation scientists and their colleagues will discuss their progress in rehabilitation research at the upcoming 65th Annual American Academy of Neurology Conference at the San Diego Convention Center in San Diego, CA, March 16 – 23. A.M. Barrett, MD, director of Stroke Rehabilitation at Kessler Foundation will present on Pharmacologic Enhancement of Stroke Rehabilitation on Friday March 22, 2013 as part of a Specialty in Focus session on Neurorehabilitation Enhancement Techniques. This session addresses the contribution of brain ...

Humans aren't the only species with a sweet tooth. Research from North Carolina State University shows that the invasive spotted-wing vinegar fly (Drosophila suzukii) also prefers sweet, soft fruit – giving us new insight into a species that has spread across the United States over the past four years and threatens to cause hundreds of millions of dollars in damage to U.S. fruit crops. "Because we know that D. suzukii prefers softer, sweeter fruit, we can focus our research efforts into which wild fruits may serve as reservoirs for this species and help identify new crops ...

COLUMBUS, Ohio—A new National Academy of Sciences report identifies tools that would help miners devise their own means of escape when trapped underground. In part, the report suggests that The National Institute of Occupational Safety and Health (NIOSH) and the Mine Safety and Health Administration (MSHA) work closely with technology companies to develop new communications and tracking devices—ones that keep working underground after a mining accident. It also suggests that NIOSH and MSHA work with mining companies to enable frequent escape drills and extensive training ...

Mindfulness is a form of meditation therapy focused on exercising 'attentiveness'. Depression is often rooted in a downward spiral of negative feelings and worries. Once a person learns to more quickly recognise these feelings and thoughts, he or she can intervene before depression sinks in. While mindfulness has already been widely tested and applied in patients with depression, this is the first time the method has been studied in a large group of adolescents in a school-based setting, using a randomised controlled design. The study was carried out at five middle schools ...

VIDEO: Animation of spin waves excited by a transient magnetic field pulse in a nanomagnet, as simulated with NIST micromagnetics software (Object Oriented MicroMagnetic Framework, or OOMMF). Click here for more information. Researchers at the National Institute of Standards and Technology (NIST) have developed a new microscope able to view and measure an important but elusive property of the nanoscale magnets used in an advanced, experimental form of digital memory. The new instrument ...

Today archaeologists unearthed a 'Black Death' grave in London, containing more than a dozen skeletons of people suspected to have died from the plague. The victims are thought to have died during the 14th century and archaeologists anticipate finding many more as they excavate the site. The Plague is by definition a re-emerging infectious disease which affects the lungs and is highly contagious, leading to mass outbreaks across populations. History shows us that population levels suffered globally due to the plague, with around 75 million people globally perishing during ...

The genome of an extinct Australian frog has been revived and reactivated by a team of scientists using sophisticated cloning technology to implant a "dead" cell nucleus into a fresh egg from another frog species. The bizarre gastric-brooding frog, Rheobatrachus silus – which uniquely swallowed its eggs, brooded its young in its stomach and gave birth through its mouth - became extinct in 1983. But the Lazarus Project team has been able to recover cell nuclei from tissues collected in the 1970s and kept for 40 years in a conventional deep freezer. The "de-extinction" ...

Athens, Ga. – Students who date in middle school have significantly worse study skills, are four times more likely to drop out of school and report twice as much alcohol, tobacco and marijuana use than their single classmates, according to new research from the University of Georgia. "Romantic relationships are a hallmark of adolescence, but very few studies have examined how adolescents differ in the development of these relationships," said Pamela Orpinas, study author and professor in the College of Public Health and head of the Department of Health Promotion and ...

This press release is available in German. In their experiment the researchers used a carbon nanotube that was mounted between two metal electrodes, spanned a distance of about 1 µm, and could vibrate mechanically. Then, they applied an organic molecule with a magnetic spin due to an incorporated metal atom. This spin was oriented in an external magnetic field. "In this setup, we demonstrated that the vibrations of the tube are influenced directly when the spin flips parallel or antiparallel to the magnetic field," explains Mario Ruben, head of the working group ...

Anyone who needs a reason not to overindulge on St. Patrick's Day — or on any other day of the year — can view a new American Chemical Society (ACS) video on alcohol's effects on the body at http://www.BytesizeScience.com. St. Patrick's Day is this Sunday, and there are many ways to celebrate, like Irish soda bread at breakfast or corned beef and cabbage for dinner. For those celebrating St. Patrick's Day with green beer, moderation is key. Alcohol has several negative effects on your body — many of which usually amount to a miserable morning-after. Produced by the ...

Distant, dust-filled galaxies were bursting with newborn stars much earlier in cosmic history than previously thought, according to newly published research. So-called "starburst galaxies" produce stars at the equivalent of a thousand new suns per year. Now, astronomers have found starbursts that were churning out stars when the universe was just a billion years old. "I find that pretty amazing," said Joaquin Vieira, a postdoctoral scholar at the California Institute of Technology and leader of the study. "These aren't normal galaxies. These galaxies [reveal star formation] ...

Swarming is the spontaneous organised motion of a large number of individuals. It is observed at all scales, from bacterial colonies, slime moulds and groups of insects to shoals of fish, flocks of birds and animal herds. Now physicists Maksym Romenskyy and Vladimir Lobaskin from University College Dublin, Ireland, have uncovered new collective properties of swarm dynamics in a study just published in EPJ B. Ultimately, this could be used to control swarms of animals, robots, or human crowds by applying signals capable of emulating the underlying interaction of individuals ...

CORVALLIS, Ore. – Imagine driving down a road a few times and obtaining in an hour more data about the surrounding landscape than a crew of surveyors could obtain in months. Such is the potential of mobile LIDAR, a powerful technology that's only a few years old and promises to change the way we see, study and record the world around us. It will be applied in transportation, hydrology, forestry, virtual tourism and construction – and almost no one knows anything about it. That may change with a new report on the uses and current technology of mobile LIDAR, which has ...

The dry, barren prairie around Alberta's Drumheller area was once a lush and subtropical forest on the shores of a large inland sea, with loads of wetlands inhabited by dinosaurs, turtles, crocodiles and small mammals. But that changed about 71-million-years ago, according to a new study by researchers Annie Quinney and Darla Zelenitsky in paleontology at the University of Calgary. The researchers' calculations show that drastic climate change occurred during a five-million-year period in Alberta's badlands. At this time, the wetlands dried up and the warm humid climate ...

The brain's prefrontal cortex is thought to be the seat of cognitive control, working as a kind of filter that keeps irrelevant thoughts, perceptions and memories from interfering with a task at hand. Now, researchers at the University of Pennsylvania have shown that inhibiting this filter can boost performance for tasks in which unfiltered, creative thoughts present an advantage. The research was conducted by Sharon Thompson-Schill, the Christopher H. Browne Distinguished Professor of Psychology and director of the Center for Cognitive Neuroscience, and Evangelia ...

Geoengineering, the use of human technologies to alter the Earth's climate system — such as injecting reflective particles into the upper atmosphere to scatter incoming sunlight back to space — has emerged as a potentially promising way to mitigate the impacts of climate change. But such efforts could present unforeseen new risks. That inherent tension, argue two professors from UCLA and Harvard, has thwarted both scientific advances and the development of an international framework for regulating and guiding geoengineering research. In an article to be published March ...

Mindfulness — paying attention to one's current experience in a non-judgmental way — might help us to learn more about our own personalities, according to a new article published in the March 2013 issue of Perspectives on Psychological Science, a journal of the Association for Psychological Science. Recent research has highlighted the fact that we have many blind spots when it comes to understanding our patterns of thinking, feeling, and behaving. Despite our intuition that we know ourselves the best, other people have a more accurate view of some traits (e.g., intellect) ...