CHAPEL HILL, N.C. - Head and neck squamous cell carcinoma (HNSCC) is the seventh most common form of cancer in the United States, but other than an association with the human papillomavirus, no validated molecular profile of the disease has been established. By analyzing data from DNA microarrays, a UNC-led team has completed a study that confirms the presence of four molecular classes of the disease and extends previous results by suggesting that there may be an underlying connection between the molecular classes and observed genomic events, some of which affect known ...

PHILADELPHIA – For years researchers have been searching for a way to treat diabetics by reactivating their insulin-producing beta cells, with limited success. The "reprogramming" of related alpha cells into beta cells may one day offer a novel and complementary approach for treating type 2 diabetes. Treating human and mouse cells with compounds that modify cell nuclear material called chromatin induced the expression of beta cell genes in alpha cells, according to a new study that appears online in the Journal of Clinical Investigation. "This would be a win-win situation ...

Boulder, Colo., USA – Geology articles posted online ahead of print on 20 Feb. 2013 include several modeling and simulation studies as well as studies on the Exmouth Sub-basin, Australia; the West Kunlun Range, northern Tibetan Plateau; Krakenes Lake, Norway; the Azores islands; and the hot springs of Colorado. The 12 new papers cover a variety of topics: Taking the easiest pathway to Earth's surface A challenge to climate change and biotic factors to explain post-glacial lake acidification Upper-crustal shortening in the Tibetan Plateau Analysis of diamonds with ...

Alexandria, VA – Geoscience Currents #70 presents the final data collected from the GeoConnection Recruitment Packets distributed from 2009 to 2011. The packets, which included informational brochures from several of AGI's member societies, fliers with internship information, and a copy of EARTH Magazine's "Workforce" edition, also offered students the opportunity to register with up to five of AGI's professional member societies for free. This endeavor was meant to increase student participation in the greater geoscience community. Geoscience Currents #70 details ...

Washington University engineering researchers have created a new type of air-cleaning technology that could better protect human lungs from allergens, airborne viruses and ultrafine particles in the air. The device, known as the SXC ESP, was created by a team led by Pratim Biswas, PhD, the Lucy & Stanley Lopata Professor and chair of the Department of Energy, Environmental & Chemical Engineering in the School of Engineering & Applied Science. A recent study of the device, published in Applied and Environmental Microbiology, found that it could help to prevent respiratory ...

NASA's Aqua satellite passed over Cyclone Haruna after it made landfall in southwestern Madagascar. Haruna's center made landfall near Manombo, Madagascar around 0600 UTC (1 a.m. EST/U.S.) The METEO-7 satellite captured a visible image of Haruna at the time of landfall and showed that its eye had already become cloud-filled. The Moderate Resolution Imaging Spectroradiometer (MODIS) instrument aboard NASA's Aqua satellite captured a visible image of Tropical Storm Haruna on Feb. 22 at 1105 UTC (6:05 a.m. EST) after it moved inland and its eye was completed cloud-filled. ...

A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells, Johns Hopkins researchers report. Their discovery has wide-ranging implications, they say, given the importance of this copying — known as DNA replication — and new cell growth to many of the body's functions and in such diseases as cancer. "We've long known that this protein, HIF-1α, can switch hundreds of genes on or off in response to low oxygen conditions," says Gregg Semenza, M.D., Ph.D., ...

PA's adoption laws make it possible for families to grow Article provided by The Law Offices of Marguerite Nealon Visit us at http://www.pafamilylaw.com Pennsylvania, as a whole, is quite liberal in its policies regarding adoption. For instance, the state does not have any age restrictions, thereby allowing persons above the age of eighteen to be adopted. Furthermore, Pennsylvania allows adoption by both single adults and married couples. Most recently, the state made it legal for same-sex couples to adopt a child. Pennsylvania's liberal adoption regulations make ...

Can sniffs from drug-sniffing dogs establish probable cause? Article provided by Mark K. Tyndall, P.C. Visit us at http://www.virginiadefenselaw.com In October, the United States Supreme Court heard two cases regarding the relationship between evidence from a drug-sniffing dog and probable cause. In both cases, the justices will determine if the sniff of a trained drug-sniffing dog can establish probable cause for an officer to obtain a warrant. Probable cause is the threshold law enforcement must meet to perform a search, request a warrant or make an arrest. ...

NHTSA proposes noise standards for hybrids Article provided by Law Offices of Robert Hamparyan Visit us at http://www.yourcaliforniaaccidentattorney.com Due to rising gas prices, hybrid vehicles have become more popular in recent years. Although hybrids offer the latest technology and the highest fuel efficiency, they can be dangerous to bicyclists and pedestrians. The reason: they operate so silently at low speeds that it is very difficult to hear them as they approach. To address the problem, the National Highway Traffic Safety Administration (NHTSA) has recently ...

Recent accidents reveal dangers of pedestrian accidents Article provided by Schiller Law Firm Visit us at http://www.theschillerlawfirm.com Walking and biking are enjoyable hobbies for numerous South Carolina residents. However, recent news stories demonstrate how common pedestrian accidents are. Pedestrian accidents in South Carolina In one case, an 87-year old man was pinned underneath a pickup truck. According to the Herald Online, the man was walking with a relative outside a VA Medical Center when the pickup truck jumped a curb and struck the man. The ...

Insufficient savings the biggest hurdle to financial wellness Article provided by BRENNER BRENNER & SPILLER Visit us at http://www.brennerlawoffice.com Whether it's a broken-down car, an unexpected illness or injury, or a suddenly-leaky roof, everyone experiences unplanned emergency expenses at some point during their lives. But why are some people able to adapt to these expenses, while for others they signal the first step on the road to financial crisis? The secret is in savings. People who put money away each month to build up a cash reserve are much more ...

Divorce and property division in Texas Article provided by Law Offices of Lee Hernandez, P.C. Visit us at http://www.leehernandez.com When couples decide to get a divorce, most will face a long road as they decide how to split their property and assets. The state in which they live can also dictate some of the terms of property division. Texas law governs the division of marital property upon divorce and in general, even though Texas is a community property state, the law does not require a 50-50 division of the property. The court will divide the property in ...

How divorce affects your insurance Article provided by Law Offices of James V. Sansone Visit us at http://www.jamessansonelaw.com When a couple divorces, they have a lot to worry about -- from dividing their assets to making decisions about the custody and care of their children -- so how their divorce will affect insurance matters might be one of the last things on their minds. The following are some insurance concerns that anyone going through a divorce should consider. Health insurance When there are children involved in a divorce, generally the parent ...

West Virginians: Don't text while behind the wheel Article provided by Law Offices of Kelly R. Reed, PLLC Visit us at http://www.reedkimble.com If you drive regularly, the chances are high that you have been stuck behind a vehicle driving erratically only to discover the cause was a driver talking on a cellphone. In West Virginia and across the United States, the dangers of distracted driving have become more apparent in the past few years, as cellphones have become an indispensible part of most people's lives. A marked increase in the number of car accidents caused ...

Arrest and police interrogation: know your rights! Article provided by The Law Office of Matthew J. Davenport, P.A. Visit us at http://www.mattdavenportlaw.com The U.S. Constitution provides significant protections to people against abuses by law enforcement. Specifically, it sets parameters for arrests and police questioning. Violations of these parameters will undermine a criminal case brought by the government. Because the Constitution's protections are so important, it is critical that people understand their rights so they can assert them when necessary. Fourth ...

Car accidents lead to recovery for those injured by other drivers Article provided by Murphy & Johnson, S.C. Visit us at http://www.murphypaulson.com Whenever we see a car accident, we often wonder what happened to cause the crash. We want to know what types of behaviors to avoid so that we do not find ourselves in a similar situation. Even though we might be practicing safe driving habits, we also must rely on other drivers to do the same, which may not be the case as often as we would hope. Despite the widespread efforts of both state and federal government ...

State agencies cite several nursing homes for deficiencies in care Article provided by Kenney & Conley, P.C. Visit us at http://www.kenneyconley.com Nursing home neglect and abuse is a serious problem in the United States. While Americans hope that their loved ones are in good hands, sometimes, this is not the case. Examples of nursing home neglect include falls, medication errors, bedsores, malnutrition and other matters of disregard. To combat the issue of abuse in care facilities and ensure that residents are sufficiently cared for, state agencies inspect ...

Senators aim to make private student loans dischargeable in bankruptcy Article provided by Charles R. Nettles, Attorney at Law Visit us at http://www.cnbankruptcylaw.com Although student loan debt is a growing burden for many in America, since 2005 it is almost always ineligible for discharge in personal bankruptcy. A group of U.S. senators has re-introduced legislation that would make private student loan debt dischargeable, though, aiming to help people emerge from bankruptcy with a fresh financial start and to make money available for other investments that would ...

Scientists develop a new way to detect mold in homes Article provided by Triangle Law Group Visit us at http://www.trianglelawgroup.net After moving into a newly constructed home, the last thing you want to deal with is mold contamination. Mold contamination in a home can cause serious health issues for the whole family. Sometimes, mold contamination is due to defects in construction. If this is the case, there may be a legal remedy available to the homeowner in the form of monetary damages for the harm caused. New way to detect mold contamination Mold contamination ...

West Virginia Supreme Court to rule on Massey mine fire liability Article provided by Fox Law Office, PLLC Visit us at http://www.foxlaw1.net In 2006, a West Virginia coal mine run by Massey Energy caught fire, killing two miners. Now, the widows of the two deceased miners are looking to hold the federal government accountable for what they say was a negligent failure to properly inspect the mine. The West Virginia Supreme Court heard arguments in the coal mining accident case in October 2012. There, the widows alleged that the federal Mine Safety and Health ...

New York City construction accidents on the rise Article provided by Chiariello & Chiariello Visit us at http://www.chiariello.com/ Lack of oversight may be to blame for the rise in construction accidents in New York City between 2011 and 2012. New statistics show that accident and construction injury rates have increased as the city cuts down on the number of inspections it performs in a year. Unfortunately, this means that many construction workers will by injured or lose their lives due to workplace hazards. Crane collapses in Queens A crane collapse ...

Supreme Court to Rule on Important DUI Case Article provided by Melowski & Associates, LLC. Visit us at http://www.melowskilaw.com Last month, the United States Supreme Court heard oral arguments in a case involving an arrest for driving under the influence (DUI) that may have serious implications for drivers' Fourth Amendment rights. Specifically, Missouri v. McNeely presents the question whether police may take a blood sample from someone suspected of DUI without a warrant and without the person's consent. Facts of McNeely At approximately 2:00am on ...

Innovations on the dashboard may increase the risk of distracted driving Article provided by Kedzie Law Offices, P.C. Visit us at http://www.kedzielaw.com KITT is making a comeback. The popular show from the eighties staring David Hasselhoff and his talking car, KITT, may soon become a reality. Vehicles with amazing innovations were on display this year at the Consumer Electronics Show (CES). Although the vehicles were not yet able to hold a conversation with their drivers, advances did include the ability to connect to the Internet through the dashboard allowing ...

Moving your Arizona household if you are the custodial parent Article provided by Thompson Law Firm Visit us at http://www.cmthompsonlaw.com/ Once everyone has settled into new lives after divorce, inevitably things will continue to evolve for each ex-spouse. A divorced parent with custody of a child of the previous marriage may need or want to relocate to a new home with the child. Impact of distance A custodial parent move will probably affect the relationship of the child with the other parent. There may be logistical and financial impact on continuing ...