The authors say that, while helmets reduce head injuries and their use should be encouraged, in the context of existing safety campaigns, the impact of legislation seems to be minimal. Cyclists are vulnerable road users and head injuries among cyclists account for 75% of cycling related deaths. But debate exists about whether or not helmet legislation is an effective strategy to reduce serious head injuries among cyclists of all ages. So a team of researchers based in Canada examined changes in the rate of cycling related head injuries associated with helmet legislation ...

The journal says it is committed to "stepping up its commitment to patient partnership" and wants to "develop a strategy for patient partnership that will be reflected across the entire journal." In an editorial, BMJ editors along with Professor Victor Montori and Dave Paul at the Mayo Clinic in the US, argue that the preservation of institutional bureaucracies, as well as professional and commercial vested interests, "have consistently trumped the interests of patients." They say clinicians and patients need to work in partnership "if we are to improve healthcare and ...

Having a hysterectomy with or without ovary removal in mid-life does not increase a woman's risk of cardiovascular disease compared to women who reach natural menopause, contrary to many previously reported studies, according to research published online today in the Journal of the American College of Cardiology. "Middle-aged women who are considering hysterectomy should be encouraged because our results suggest that increased levels of cardiovascular risk factors are not any more likely after hysterectomy relative to after natural menopause," said Karen A. Matthews, ...

A combination of two FDA-approved osteoporosis drugs with different mechanisms of action was found to increase bone density better than treatment with either drug alone in a small clinical trial. As reported in paper receiving Online First publication in The Lancet, Massachusetts General Hospital (MGH) investigators found that treatment combining denosumab (Prolia) and teriparatide (Forteo) was superior to single-agent treatment in a 12-month trial in women with postmenopausal osteoporosis. The authors note that additional study is required before their findings should ...

Community groups in rural Vietnam comprised of local health workers, politicians and laywomen (Maternal and Newborn Health Groups) set up to tackle challenges to maternal and neonatal health may reduce the neonatal death rate after three years and increase antenatal care attendance, according to a study by researchers from Sweden and Vietnam published in this week's PLOS Medicine. These findings are important as they show that is it feasible to implement community-based activity into the public sector system at low cost. The researchers (also the authors of this paper) ...

An international team of scientists have revealed a new species of ichthyosaur (a dolphin-like marine reptile from the age of dinosaurs) from Iraq, which revolutionises our understanding of the evolution and extinction of these ancient marine reptiles. The results, produced by a collaboration of researchers from universities and museums in Belgium and the UK and published today (May 15) in Biology Letters, contradict previous theories that suggest the ichthyosaurs of the Cretaceous period (the span of time between 145 and 66 million years ago) were the last survivors ...

AURORA, Colo. (May 14, 2013) – A device commonly used to treat dangerous heart rhythms may cause more issues for patients than a simpler version of the same device. The implantable cardioverter-defibrillator (ICD) prevents sudden cardiac death by detecting irregularities and delivering an electrical jolt to restart the heart. An analysis led by researchers at University of Colorado School of Medicine and published in the May 15 issue of The Journal of the American Medical Association focused on people getting ICDs who do not have a clear reason for pacemaker support. ...

ANN ARBOR, Mich. – African-Americans know the signs of stroke, but concerns about medical cost, ambulance response time and unfamiliarity with the need for prompt hospital care impacted whether they called 9-1-1 immediately. A study that included 77 African-Americans in Flint, Mich., revealed barriers among adults and youth in getting help for stroke which is significantly higher among African-Americans and leads to more deaths and disability. Adults mentioned the cost of paying for an ambulance, while young people worried about staying calm if they witnessed someone ...

A novel drug may help increase the effectiveness of radiation therapy for the most deadly form of brain cancer, report scientists at Virginia Commonwealth University Massey Cancer Center. In mouse models of human glioblastoma multiforme (GBM), the new drug helped significantly extend survival when used in combination with radiation therapy. Recently published in the journal Clinical Cancer Research, the study provides the first preclinical evidence demonstrating that an ATM kinase inhibitor radiosensitizes gliomas. Gliomas are brain tumors that originate from glial cells, ...

Boston, MA – In new research published online May 13, 2013 in Advanced Materials, researchers from Brigham and Women's Hospital (BWH) are the first to report that synthetic silicate nanoplatelets (also known as layered clay) can induce stem cells to become bone cells without the need of additional bone-inducing factors. Synthetic silicates are made up of simple or complex salts of silicic acids, and have been used extensively for various commercial and industrial applications, such as food additives, glass and ceramic filler materials, and anti-caking agents. Silicate ...

PHILADELPHIA — Labs around the world, and a core group at Penn, have been studying recently described populations of immune cells called innate lymphoid cells (ILCs). Some researchers liken them to foot soldiers that protect boundary tissues such as the skin, the lining of the lung, and the lining of the gut from microbial onslaught. They also have shown they play a role in inflammatory disease, when the body's immune system is too active. In animal studies, group-2 innate lymphoid cells (ILC2s) confer immunity during a parasitic infection in mice and are also involved ...

The song, "Get Happy," famously performed by Judy Garland, has encouraged people to improve their mood for decades. Recent research at the University of Missouri discovered that an individual can indeed successfully try to be happier, especially when cheery music aids the process. This research points to ways that people can actively improve their moods and corroborates earlier MU research. "Our work provides support for what many people already do – listen to music to improve their moods," said lead author Yuna Ferguson, who performed the study while she was an MU doctoral ...

Sporting events can bring a community together, such as when the Louisville Cardinals won the NCAA championship and University of Louisville campus was filled with camaraderie. They also can fuel bitter rivalries, such as the long-standing animosity between the St. Louis Cardinals and the Chicago Cubs. A University of Missouri study has found that testosterone levels during group competition are modulated depending on the relationships among the competitors and may be related to the formation of alliances in warfare. "One interesting thing about humans is that we are ...

New Rochelle, NY, May 14, 2013—Animals, insects, and plants use a variety of sensing mechanisms to detect invading pathogens such as viruses. One complex and effective antiviral defense system they share is based on recognition of double-stranded RNA (dsRNA), often produced when a virus invades a host cell. New information leading to a clearer understanding of the mechanisms underlying viral dsRNA sensing is presented in a comprehensive Review article published in Journal of Interferon & Cytokine Research, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers. ...

Forget apples – lifting weights and doing cardio can also keep the doctors away, according a new study by researchers at the University of British Columbia and Vancouver Coastal Health Research Institute. The study, published today in the online journal PLOS ONE, followed 86 women, aged 70- to 80-years-old, who were randomly assigned to participate in weight training classes, outdoor walking classes, or balance and toning classes (such as yoga and pilates) for six months. All participants have mild cognitive impairment, a well-recognized risk factor for Alzheimer's disease ...

WASHINGTON, DC—A study released today by George Washington University School of Public Health and Health Services (SPHHS) researchers offers an in-depth look at hospitals nationwide and admissions to intensive care units (ICU). The study, published in the journal Academic Emergency Medicine, finds a sharp increase—nearly 50 percent—in ICU admissions coming from U.S. emergency departments. "These findings suggest that emergency physicians are sending more patients on to the ICU," said SPHHS researcher and lead author Peter Mullins. "The increase might be the result of ...

The time may be fast approaching for researchers to take better advantage of the vast amount of valuable patient information available from U.S. electronic health records. Lian Duan, an NJIT computer scientist with an expertise in data mining, has done just that with the recent publication of "Adverse Drug Effect Detection," IEEE Journal of Biomedical and Health Informatics (March, 2013). The article spotlights a new and promising way of using a combination of commonly used existing algorithms to root out more information about adverse drug reactions within electronic ...

While global attention has for decades been focused on reducing maternal mortality, population-based data on other causes of death among women of reproductive age has been virtually non-existent. A study conducted by researchers at the Johns Hopkins Bloomberg School of Public Health found that non-communicable diseases accounted for 48 percent of 1,107 investigated female deaths in rural Bangladesh between 2002 and 2007. The findings lend urgency to review global health priorities to address neglected and potentially fatal non-communicable diseases affecting rural women ...

In 1700, a massive earthquake struck the west coast of North America. Though it was powerful enough to cause a tsunami as far as Japan, a lack of local documentation has made studying this historic event challenging. Now, researchers from the University of Pennsylvania have helped unlock this geological mystery using a fossil-based technique. Their work provides a finer-grained portrait of this earthquake and the changes in coastal land level it produced, enabling modelers to better prepare for future events. Penn's team includes Benjamin Horton, associate professor ...

A Brazilian investigative team, collaborating with a Simon Fraser University researcher, is citing an urgent need for targeted interventions among young crack users in cities throughout Brazil, identified as the world's biggest crack market, and further research to better address the problem. SFU health sciences professor Benedikt Fischer and his Brazilian collaborators carried out a study of 160 young adult crack users in Rio de Janeiro and Salvador. Its findings paint a somber picture of socially disenfranchised drug users with extensive health problems and involvement ...

CAMBRIDGE, MA -- When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ravaged their DNA. A new finding from MIT researchers may offer a way to overcome that resistance: The team has identified a key protein involved in an alternative death pathway known as programmed necrosis. Drugs that mimic the effects of this protein could push cancer cells that are resistant to apoptosis into necrosis instead. While apoptosis ...

LOUISVILLE, Ky. – It seems that even for the smallest of people, a gentle massage may be beneficial. Newborn intensive care units (NICUs) are stressful environments for preterm infants; mechanical ventilation, medical procedures, caregiving activities and maternal separation create these stressful conditions. Born under-developed, preemies have an immature autonomic nervous system (ANS), which controls stress response and recovery. For a preemie, even a diaper change is stressful and the immature ANS over reacts to these stressors. Since preterm infants can't process ...

RIVERSIDE, Calif. (http://www.ucr.edu)— The atom-sized world of carbon nanotubes holds great promise for a future demanding smaller and faster electronic components. Nanotubes are stronger than steel and smaller than any element of silicon-based electronics—the ubiquitous component of today's electrical devices—and have better conductivity, which means they can potentially process information faster while using less energy. The challenge has been figuring out how to incorporate all those great properties into useful electronic devices. A new discovery by four scientists ...

A novel avian-origin reassortant influenza A (H7N9) virus emerged in China in February 2013, and is associated with severe lower respiratory tract diseases. To date, more than 100 human cases of infection, including at least 20 deaths, have been reported in China. Three early cases of infection were described in Hangzhou, Zhejiang Province, China. The general clinical features of the three patients were similar to the previously reported cases in China. Two of the three patients had a history of direct contact with live poultry markets. Interestingly, poultry cage swabs ...

Imagine what Paula Spurlock must have been going through. Shortly after having a hip replaced in 2011, the trouble started. "I had horrible itching, really bad migraines and intense pain throughout my body," she said. "I couldn't take it. Every single thing in me itched." After many months and several trips to specialists, Spurlock was told it could be anything from food allergies to her medication. But no matter what she changed, the symptoms persisted and Spurlock resigned herself to a life of misery. "I just kind of thought that's what life was going to be like," ...