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Mayo Clinic suicide prevention expert outlines new steps to tackle military suicide

2012-09-10
ROCHESTER, Minn. -- The suicide rate in the U.S. Army now exceeds the rate in the general population, and psychiatric admission is now the most common reason for hospitalization in the Army. These concerning trends are described by Timothy Lineberry, M.D., a Mayo Clinic psychiatrist and suicide expert for the Army, in the September edition of Mayo Clinic Proceedings. In the article, he also outlines steps to assess and address military suicide -- an issue he calls a major public health concern. Dr. Lineberry proposes greater use of gun locks, improving primary care for ...

Increase in metal concentrations in Rocky Mountain watershed tied to warming temperatures

2012-09-10
Warmer air temperatures since the 1980s may explain significant increases in zinc and other metal concentrations of ecological concern in a Rocky Mountain watershed, reports a new study led by the U.S. Geological Survey and the University of Colorado Boulder. Rising concentrations of zinc and other metals in the upper Snake River just west of the Continental Divide near Keystone, Colo., may be the result of falling water tables, melting permafrost and accelerating mineral weathering rates, all driven by warmer air temperatures in the watershed. Researchers observed a ...

Tight blood sugar control for pediatric cardiac surgery patients does not improve outcomes

2012-09-10
Ann Arbor, Mich. — Tight blood sugar control in the intensive care unit for pediatric cardiac surgery patients does not improve patients' infection rate, mortality, length of stay or organ failure when compared to standard care, new research shows. The research, conducted at the University of Michigan's C.S. Mott Children's Hospital and Boston Children's Hospital, will be published Online First in the New England Journal of Medicine Sept. 7. "Post-operative complications for infants and young children who have cardiac surgery remains common, so we want to identify risk ...

No proof that patients lose weight after joint replacement surgery

2012-09-10
Hip and knee replacements are now a common surgical procedure with more than 700,000 total joint arthroplasties (TJAs) performed in the US every year. Due to the reduction in pain and increases in mobility experienced after having a TJA, it could be expected that weight loss may occur as a by-product of the surgery. But is this the case? This is the question posed by Maria Inacio, a doctoral candidate from the San Diego State University/University of California, San Diego, who is employed at Kaiser Permanente, and her colleagues at those institutions. They conducted ...

Metabolic engineer synthesizes key breast milk ingredient, makes research possible

2012-09-10
URBANA - A University of Illinois microbial engineer has synthesized a sugar in human milk that is thought to protect babies from pathogens. That's important because 2FL, the shorthand scientists use to describe this human milk oligosaccharide (HMO), has not been added to infant formula because HMOs are incredibly expensive. "We know these oligosaccharides play a vital role in developing a breast-fed baby's gut microbiota and in strengthening their immunity. 2FL (2-fucosyllactose) is the most abundant HMO in breast milk," said Michael Miller, a U of I professor of food ...

Case Western Reserve researchers create short-term memories in-vitro

2012-09-10
Ben W. Strowbridge, PhD, Professor of Neurosciences and Physiology/Biophysics, and Robert A. Hyde, a fourth year MD/PhD student in the neurosciences graduate program at Case Western Reserve University School of Medicine, have discovered how to store diverse forms of artificial short-term memories in isolated brain tissue. "This is the first time anyone has found a way to store information over seconds about both temporal sequences and stimulus patterns directly in brain tissue," says Dr. Strowbridge. "This paves the way for future research to identify the specific brain ...

Scientists put a pox on dog cancer

Scientists put a pox on dog cancer
2012-09-10
CHAMPAIGN, Ill. — Researchers report that myxoma – a pox virus that afflicts rabbits but not humans, dogs or any other vertebrates so far studied – infects several different types of canine cancer cells in cell culture while sparing healthy cells. The study adds to the evidence that viruses or modified viruses will emerge as relatively benign cancer treatments to complement or replace standard cancer therapies. The new study, reported in the American Journal of Veterinary Research, is unique in that it focused on spontaneously occurring cancers in dogs. This allowed the ...

Predicting wave power could double marine-based energy

2012-09-10
In the search for alternative energy, scientists have focused on the sun and the wind. There is also tremendous potential in harnessing the power of the ocean's waves, but marine energy presents specific challenges that have made it a less promising resource. It's a challenge to tune Wave Energy Converters (WECs) so that they are able to harvest the maximum energy from waves, which differ in terms of their size and force. This unpredictability leads to intermittent energy collection. WECs also need to withstand the harsh winds and storms to which they are subjected in ...

Lawrence Livermore researchers find wind power not enough to affect global climate

2012-09-10
LIVERMORE, Calif. --Though there is enough power in the earth's winds to be a primary source of near-zero emission electric power for the world, large-scale high altitude wind power generation is unlikely to substantially affect climate. That is the conclusion of a Lawrence Livermore National Laboratory climate scientist and collaborators who studied the geophysical limits to global wind power in a paper appearing in the Sept. 9 edition of the journal, Nature Climate Change. "The future of wind energy is likely to be determined by economic, political and technical constraints ...

Too soon? Too late? Psychological distance matters when it comes to humor

2012-09-10
Joking around can land us in hot water. Even the professionals often shoot themselves comedically in the foot. Last month, comedian Jeffrey Ross's routine at a roast of Rosanne Barr was censored when he joked about the shooting in Aurora, Colorado. "Too soon!" everyone said. And yet, it's not quite as simple as certain topics being "too soon" to joke about. Two weeks after 9/11, The Onion was able to successfully publish a satirical issue about the terrorist attacks. So the question is: When are tragedies okay to joke about -- and when are they not? According to ...

Researchers find first evidence for a genetic cause for Barrett's oesophagus

2012-09-10
Genetic variations that are linked with the onset of Barrett's oesophagus (BE), a pre-cancerous condition of the lower end of the gullet, have been identified for the first time. The discovery of variations in regions on two chromosomes makes it possible to develop screening tests for people at high risk of developing the disease. Although it's been thought for some time that there may be genetic causes for BE as well as environmental ones, such as drinking alcohol and eating fatty food, so far researchers have not found any genetic variations that are associated with ...

Genetic clues to the causes of primary biliary cirrhosis!

2012-09-10
Researchers have newly identified three genetic regions associated with primary biliary cirrhosis (PBC), the most common autoimmune liver disease, increasing the number of known regions associated with the disorder to 25. The team used a DNA microchip, called Immunochip, to survey more thoroughly regions of the genome known to underlie other autoimmune diseases to discover if they play a role also in PBC susceptibility. By combining the results from this survey with details of gene activity from a database called ENCODE, they were able to identify which cells types are ...

Giant 'balloon of magma' inflates under Santorini

2012-09-10
A new survey suggests that the chamber of molten rock beneath Santorini's volcano expanded 10-20 million cubic metres – up to 15 times the size of London's Olympic Stadium – between January 2011 and April 2012. The growth of this 'balloon' of magma has seen the surface of the island rise 8-14 centimetres during this period, a team led by Oxford University scientists has found. The results come from an expedition, funded by the UK's Natural Environment Research Council, which used satellite radar images and Global Positioning System receivers (GPS) that can detect movements ...

OHSU research helps explain why an AIDS vaccine has been so difficult to develop

2012-09-10
PORTLAND, Ore. — For decades, a successful HIV vaccine has been the Holy Grail for researchers around the globe. Yet despite years of research and millions of dollars of investment, that goal has still yet to be achieved. Recent research by Oregon Health & Science University scientists explains a decades-old mystery as to why slightly weakened versions of the monkey AIDS virus were able to prevent subsequent infection with the fully virulent strain, but were too risky for human use, and why severely compromised or completely inactivated versions of the virus were not effective ...

Large lung cancer study shows potential for more targeted therapies

2012-09-10
A nationwide consortium of scientists has reported the first comprehensive genetic analysis of squamous cell carcinoma of the lung, a common type of lung cancer responsible for about 400,000 deaths each year. "We found that almost 75 percent of the patients' cancers have mutations that can be targeted with existing drugs -- drugs that are available commercially or for clinical trials," says one of the lead investigators, Ramaswamy Govindan, MD, an oncologist at Washington University School of Medicine in St. Louis and co-chair of the lung cancer group of The Cancer Genome ...

Protecting genes, one molecule at a time

2012-09-10
An international team of scientists have shown at an unprecedented level of detail how cells prioritise the repair of genes containing potentially dangerous damage. The research, published in the journal Nature and involving academics from the University of Bristol, the Institut Jacques-Monod in France and Rockefeller University in the US, studied the action of individual molecules in order to understand how cellular repair pathways are triggered. The genetic information that forms the "instruction booklet" for cells is encoded in the molecular building blocks of DNA, ...

Nano-velcro clasps heavy metal molecules in its grips

2012-09-10
Mercury, when dumped in lakes and rivers, accumulates in fish, and often ends up on our plates. A Swiss-American team of researchers led by Francesco Stellacci at the Ecole Polytechnique Fédérale de Lausanne (EPFL) and Bartosz Grzybowski at Northwestern University has devised a simple, inexpensive system based on nanoparticles, a kind of nano-velcro, to detect and trap this toxic pollutant as well as others. The particles are covered with tiny hairs that can grab onto toxic heavy metals such as mercury and cadmium. This technology makes it possible to easily and inexpensively ...

UNC Lineberger scientists lead definition of key lung cancer genome

2012-09-10
In the September 9, 2012 early online edition of Nature, scientists with The Cancer Genome Atlas (TCGA) report that they have characterized the lung squamous cell carcinoma genome. Squamous cell carcinoma is the second most common form of lung cancer, a disease that kills more Americans than any other type of cancer. The national team of scientists examined tumor samples from 178 patients with untreated lung squamous cell carcinoma and completed genetic analysis of the tumors, work that paves the way for developing better, more targeted therapies to treat the cancer. ...

New potential targets discovered for treating squamous cell lung cancers

2012-09-10
Cambridge and Boston, MA. Sunday, September 9, 2012 – A new paper published online in Nature holds out hope that people with the second most common type of lung cancer may one day benefit from targeted therapies that have transformed treatments for other lung cancer patients. Squamous cell lung cancer kills more people each year than breast, colorectal, or prostate cancer, ranking second only to lung adenocarcinoma in the number of deaths it causes. But unlike the most common form of lung cancer, squamous cell carcinoma has no treatments aimed at the specific genetic ...

Research finds novel airborne germ-killing oral spray effective in fighting colds and flu

2012-09-10
University Hospitals Case Medical Center clinical researchers will present findings about a one-two punch to prevent colds and flu in San Francisco at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) on Sept. 9. The research team is presenting data in two poster presentations that a new oral antiseptic spray is effective in killing 99.9 percent of infectious airborne germs. Findings from these two presentations led to the development of Halo Oral Antiseptic, a first-of-its kind germ-fighting spray which is currently on store shelves. "Respiratory ...

Wolf mange part of nature's cycle

2012-09-10
Mange and viral diseases have a substantial, recurring impact on the health and size of reintroduced wolf packs living in Yellowstone National Park, according to ecologists. Following the restoration of gray wolves to Yellowstone in 1996, researchers collected blood from the animals to monitor parasite-induced disease and death. They also tracked the wolves in each pack to follow their survival and allow additional data-gathering. "Many invasive species flourish because they lack their native predators and pathogens, but in Yellowstone we restored a native predator ...

Forest mortality and climate change: The big picture

2012-09-10
Washington, D.C.— Over the past two decades, extensive forest death triggered by hot and dry climatic conditions has been documented on every continent except Antarctica. Forest mortality due to drought and heat stress is expected to increase due to climate change. Although research has focused on isolated incidents of forest mortality, little is known about the potential effects of widespread forest die-offs. A new analysis of the current literature on this topic by Carnegie's William and Leander Anderegg is published September 9 in Nature Climate Change. Along with ...

Enough wind to power global energy demand

2012-09-10
Washington, D.C.— There is enough energy available in winds to meet all of the world's demand. Atmospheric turbines that convert steadier and faster high-altitude winds into energy could generate even more power than ground- and ocean-based units. New research from Carnegie's Ken Caldeira examines the limits of the amount of power that could be harvested from winds, as well as the effects high-altitude wind power could have on the climate as a whole. Their work is published September 9 by Nature Climate Change. Led by Kate Marvel of Lawrence Livermore National Laboratory, ...

Marijuana use may increase risk of testicular cancer

2012-09-10
A new study from the University of Southern California (USC) has found a link between recreational marijuana use and an increased risk of developing subtypes of testicular cancer that tend to carry a somewhat worse prognosis. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings suggest that the potential cancer-causing effects of marijuana on testicular cells should be considered not only in personal decisions regarding recreational drug use, but also when marijuana and its derivatives are used for therapeutic purposes in ...

Continuing management needed for most threatened and endangered species

2012-09-10
The Endangered Species Act (ESA)—the key US law protecting species listed as threatened or endangered—focuses on boosting species' numbers until they reach recovery thresholds and so can be taken off the ESA list. Almost 1400 species are now listed. Yet as many as 84 percent of currently listed species with management plans will face threats to their biological recovery even after they are considered "recovered" under the act, according to an article by Dale D. Goble and his colleagues in the October issue of BioScience. These species will require continuing management ...
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