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Unexpected findings at multi-detector CT scans: Less reason to worry

2012-08-27
PROVIDENCE, R.I. – A new study from Rhode Island Hospital reports that nearly seven percent of urologic multi-detector computed tomography (MDCT) scans for hematuria result in incidental findings that may be clinically important for the patient. The study is published in the American Journal of Roentgenology. It is known that urologic CT scans can sometimes show incidental findings. To date, however, there has been limited information about the prevalence and characteristics of those findings. Julie Song, M.D., a radiologist with Rhode Island Hospital's department of ...

Water research thrives as new report highlights spiralling growth year on year

2012-08-27
Stockholm, August 27, 2012 - Research into water is growing faster than the average 4% annual growth rate for all research disciplines, claims a new report presented by Elsevier and Stockholm International Water Institute (SIWI) during the 2012 World Water Week in Stockholm. The report, "The Water and Food Nexus: Trends and Development of the Research Landscape" analysed the major trends in water and food-related article output at international, national and institutional levels. Elsevier and SIWI worked closely together on creating the report, which is based on the analysis ...

Vitamin B12 deficiency: Tracing the causes

2012-08-27
This release is available in German. Vitamin B12 is vital for cell division, the synthesis of red blood cells and the functioning of the nervous system. Unable to produce the vitamin itself, the human body has to obtain it via animal proteins. So far it has been known that on its way into the cell vitamin B12 is absorbed by little organelles, so-called lysosomes. From there, the vitamin enters the cell interior with the aid of the transport protein CblF, which was discovered by the same research team three years ago. The researchers now show that a second transport ...

To cap or not to cap: Scientists find new RNA phenomenon that challenges dogma

2012-08-27
COLUMBUS, Ohio - Some RNA molecules spend time in a restful state akin to hibernation rather than automatically carrying out their established job of delivering protein-building instructions in cells, new research suggests. And instead of being a fluke or a mistake, the research suggests that this restful period appears to be a programmed step for RNA produced by certain types of genes, including some that control cell division and decide where proteins will work in a cell to sustain the cell's life. This could mean that protein production in cells is not as clear-cut ...

Tests show that adhesive could improve safety of LASIK eye surgery

2012-08-27
MANHATTAN, Kan. -- Kansas State University researchers have developed a glue mixture that may reduce risks after laser vision correction surgery. Stacy Littlechild, a recent bachelor's degree graduate in biology originally from Wakeeney, is the lead author of two studies that describe a new protocol involving fibrinogen, riboflavin and ultraviolet light that could improve the safety of the corrective surgery. One study that demonstrates the ability of a glue to bind corneal surfaces has been published in the June edition of the journal Investigative Ophthalmology ...

Merging tissue and electronics

2012-08-27
CAMBRIDGE, MA -- To control the three-dimensional shape of engineered tissue, researchers grow cells on tiny, sponge-like scaffolds. These devices can be implanted into patients or used in the lab to study tissue responses to potential drugs. A team of researchers from MIT, Harvard University and Boston Children's Hospital has now added a new element to tissue scaffolds — electronic sensors. These sensors, made of silicon nanowires, could be used to monitor electrical activity in the tissue surrounding the scaffold, control drug release or screen drug candidates for their ...

The IABP-SHOCK II study

2012-08-27
Munich, Germany – A balloon pump inserted in the aorta is currently the most widely used support device in the treatment of cardiogenic shock and, since its introduction in 1968, has been used in several million people. However, there is still only limited evidence that the intraaortic balloon pump (IABP), one of the oldest medical devices in cardiology, is actually beneficial for the patient. Only a few registry studies and clinical trials have shown that the IABP can improve blood pressure and the perfusion of the coronary arteries. Based on these studies, international ...

MBL scientists discover nerves control iridescence in squid’s remarkable 'electric skin'

MBL scientists discover nerves control iridescence in squid’s remarkable electric skin
2012-08-27
MBL, WOODS HOLE, MA-- Squid's colorful, changeable skin enables the animal--and their close relatives, cuttlefish and octopus--to display extraordinary camouflage, the speed and diversity of which is unmatched in the animal kingdom. But how squid control their skin's iridescence, or light-reflecting property, which is responsible for the animal's sparkly rainbow of color, has been unknown. In a new study, MBL (Marine Biological Laboratory) researchers Paloma Gonzalez Bellido and Trevor Wardill and their colleagues report that nerves in squid skin control the animal's ...

The PROTECT study

2012-08-27
Munich, Germany – Rates of stent thrombosis at three years were low and comparable between zotarolimus-eluting and sirolimus-eluting stents, according to findings from the PROTECT study described here today at ESC Congress 2012. Presenting the results, Professor William Wijns from the Cardiovascular Center in Aalst, Belgium, said that the decline in rates of stent thrombosis seen recently and in the PROTECT (Patient Related OuTcomes with Endeavor versus Cypher Stenting) study was probably explained by several factors, including "improvements in patient selection, procedural ...

The FAST-MI program study

2012-08-27
Munich, Germany – Data from four French nationwide registries of STEMI (ST-elevation myocardial infarction) patients initiated five years apart and covering more than 15 years show that mortality rate decreased by 68% over this period, from 13.7% to 4.4%. Around one quarter of this mortality reduction could be attributed to a change in patient characteristics. Even after adjusting for the use of primary percutaneous coronary intervention (PCI) and reperfusion therapy, there still remained a substantial decrease in early mortality rate (>60%), underlining the importance ...

The ASTRID study

2012-08-27
Munich, Germany – The German Aortic Valve Registry (GARY) was started in July 2010 and is the only registry so far to include both transcatheter aortic valve implantation (TAVI) and conventional aortic valve replacements and repair.(1) The intention is to deliver a complete picture of current and future practice of treating aortic valve disease and to deliver reliable data on the short and long-term outcome of different treatment strategies. This specifically includes data about quality of life before and after treatment besides numerous medical variables. Participation ...

The ACCESS-EU study

2012-08-27
Munich, Germany –The percutaneous catheter-based treatment of mitral regurgitation with the MitraClip system improves symptoms and cardiac function at one-year, according to results of a prospective observational study presented here today at ESC Congress 2012. ACCESS-EUROPE (ACCESS-EU) was a multicentre study of the MitraClip system in a commercial setting in 567 patients enrolled at 14 European sites, the largest group of patients evaluated to date. The results were presented by the study's co-principal investigator Professor Wolfgang Schillinger of the Universitätsmedizin ...

The ORIGIN-GRACE study

2012-08-27
Munich, Germany – A sub-study of the Outcome Reduction with an Initial Glargine Intervention (ORIGIN) trial, designed to investigate the effect of insulin glargine and omega-3 fatty acids on atherosclerosis progression, has found that, compared to standard care, only insulin glargine (a long-acting insulin) had a "modest" statistically non-significant reducing effect on the primary outcome of rate of change in maximum carotid intima media thickness (CIMT) at 12 carotid sites. However, while insulin glargine did significantly reduce the secondary outcomes of the study ...

pH-sensitive liposomal cisplatin improves peritoneal carcinomatosis treatment without side-effects

2012-08-27
Scientists at the Oswaldo Cruz Foundation and Federal University of Minas Gerais, led by Dr. Andréa Teixeira-Carvalho and Dr. Mônica Cristina de Oliveira, have developed and characterized a circulating and pH-sensitive liposome containing cisplatin (SpHL-CDDP) aiming to promote the release of cisplatin near the tumor as well as decreasing toxicity. The development of analog drugs and new formulations are current strategies for increasing the effectiveness and safety of cisplatin as an anti-peritoneal carcinomatosis drug. The results, which appear in the August 2012 issue ...

Lack of sleep found to be a new risk factor for aggressive breast cancers

2012-08-27
Lack of sleep is linked to more aggressive breast cancers, according to new findings published in the August issue of Breast Cancer Research and Treatment by physician-scientists from University Hospitals Case Medical Center's Seidman Cancer Center and Case Comprehensive Cancer Center at Case Western Reserve University. Led by Cheryl Thompson, PhD, the study is the first-of-its-kind to show an association between insufficient sleep and biologically more aggressive tumors as well as likelihood of cancer recurrence. The research team analyzed medical records and survey ...

People of normal weight with belly fat at highest death risk, Mayo Clinic study

2012-08-27
ROCHESTER, Minn. -- People who are of normal weight but have fat concentrated in their bellies have a higher death risk than those who are obese, according to Mayo Clinic research presented today at the European Society of Cardiology Congress in Munich. Those studied who had a normal body mass index but central obesity -- a high waist-to-hip ratio -- had the highest cardiovascular death risk and the highest death risk from all causes, the analysis found. "We knew from previous research that central obesity is bad, but what is new in this research is that the distribution ...

Healthy lifestyle reduces the risk of hypertension by two thirds

2012-08-27
Munich, Germany – Healthy behaviours regarding alcohol, physical activity, vegetable intake and body weight reduce the risk of hypertension by two thirds, according to research presented at the ESC Congress today. The findings were presented by Professor Pekka Jousilahti from National Institute for Health and Welfare. According to the World Health Organization, hypertension is the leading cause of mortality in the world, contributing annually to over 7 million deaths (about 15% of all deaths). Therefore, prevention of hypertension is essential to improving health and ...

Team of researchers finds a link between cold European winters and solar activity

2012-08-27
Scientists have long suspected that the Sun's 11-year cycle influences climate of certain regions on Earth. Yet records of average, seasonal temperatures do not date back far enough to confirm any patterns. Now, armed with a unique proxy, an international team of researchers show that unusually cold winters in Central Europe are related to low solar activity - when sunspot numbers are minimal. The freezing of Germany's largest river, the Rhine, is the key. Although the Earth's surface overall continues to warm, the new analysis has revealed a correlation between periods ...

Energy drinks improve heart function

2012-08-27
Munich, Germany – Consuming energy drinks can exert acute positive benefits on myocardial performance, according to research presented today at the ESC Congress by Dr Matteo Cameli from University of Siena. "In recent years the energy drink market has exploded, with more people than ever before turning to these products as quick 'pick me ups', whether to stay awake during all night study vigils or gain the edge in sport," said Dr Cameli. "With energy drinks containing both caffeine and taurine concerns have been raised of adverse effects on the heart. While caffeine increases ...

Psoriasis patients at high risk of diabetes

2012-08-27
Munich, Germany – Patients with psoriasis are at high risk of new-onset diabetes mellitus, according to research presented at ESC Congress 2012. The findings were presented at the press conference by Dr Ole Ahlehoff from Copenhagen University Hospital, Gentofte, Denmark and at the scientific session by Usman KHALID. Psoriasis is a common chronic inflammatory disease that affects approximately 125 million people worldwide. A new study of the entire Danish population confirms previous reports of increased risk of diabetes mellitus in patients with psoriasis and shows that ...

Normal weight individuals with belly fat at highest CVD risk

2012-08-27
Munich, Germany – Normal weight individuals who carry weight concentrated in their belly have a higher death risk than obese individuals, according to research presented at ESC Congress 2012. The results were presented by Dr Karine Sahakyan from the Mayo Clinic. "We knew from previous research that central obesity is bad, but what is new in this research is that the distribution of the fat is very important even in people with a normal weight," said Dr Francisco Lopez-Jimenez, senior author on the study and a cardiologist at the Mayo Clinic in Rochester, Minnesota. "This ...

Limiting TV time -- Effective strategy for preventing weight gain in children

2012-08-27
Philadelphia, PA, August 27, 2012 – Reducing television viewing may be an effective strategy to prevent excess weight gain among adolescents, according to a new study released in the September/October 2012 issue of the Journal of Nutrition Education and Behavior. Findings were based on a one-year community-based randomized trial that enrolled 153 adults and 72 adolescents from the same households. During that year, researchers from the University of Minnesota, School of Public Health Obesity Prevention Center conducted six face-to-face group meetings, sent monthly newsletters, ...

American Meteorological Society releases revised climate change statement

2012-08-27
The American Meteorological Society (AMS) today released an updated Statement on Climate Change, replacing the 2007 version that was in effect. The informational statement is intended to provide a trustworthy, objective, and scientifically up-to-date explanation of scientific issues of concern to the public. The statement provides a brief overview of how and why global climate has changed in recent decades and will continue to change in the future. It is based on the peer-reviewed scientific literature and is consistent with the majority of current scientific understanding ...

Controlling superconductors with light

Controlling superconductors with light
2012-08-27
A superconductor, which can move electrical energy with no wasteful resistance, is the holy grail of cost-effective, efficient, and "green" power production. Unlike traditional conductors such as copper or silver, which waste power resources and lose energy when they heat up, an ideal superconductor would continuously carry electrical current without losing any power. But creating a true superconductor is tricky. Though the concept of high temperature superconductors is more than two decades old, finding and controlling the right materials has been a challenge. Now Prof. ...

Little evidence supports autism treatment options in adolescents

2012-08-27
Vanderbilt University researchers studying interventions for adolescents and young adults with autism are reporting today that there is insufficient evidence to support findings, good or bad, for the therapies currently used. Although the prevalence of autism is on the rise, much remains to be discovered when it comes to interventions for this population, the researchers concluded. "Overall, there is very little evidence in all areas of care for adolescents and young adults with autism, and it is urgent that more rigorous studies be developed and conducted," said Melissa ...
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