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23andMe compares family history and genetic tests for predicting complex disease risk

23andMe compares family history and genetic tests for predicting complex disease risk
2012-10-16
MOUNTAIN VIEW, CA – October 15, 2012 – In a new theoretical study, 23andMe, the leading personal genetics company, developed a mathematical model which shows that family history and genetic tests offer different strengths. The study results suggest that both family history and genetics are best used in combination to improve disease risk prediction. The full results of the study have now been published online in the journal PLOS Genetics. Family history is most useful in assessing risks for highly common, heritable conditions such as coronary artery disease. However, ...

One foot from the grave!

One foot from the grave!
2012-10-16
Archaeologists from the University of Leicester who uncovered a grave thought to contain the skeleton of King Richard III have revealed that the remains came within inches of being destroyed by Victorian builders. The University of Leicester led the search for the Anointed King who died at the battle of Bosworth in association with Leicester City Council and the Richard III Society. The University team dug three trenches under a Leicester car park before their discovery was made. Now site director Mathew Morris has disclosed that the remains were found just inches below ...

'Biggest Loser' study finds modest diet and exercise can sustain weight loss

2012-10-16
Exercise and healthy eating reduce body fat and preserve muscle in adults better than diet alone, according to a study funded and conducted by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. The study was recently published online in Obesity and will be in a future print edition. NIDDK senior investigator Kevin Hall, Ph.D., analyzed the individual effects of daily strenuous exercise and a restricted diet by examining data from 11 participants from the reality television program "The Biggest Loser." ...

Prebiotic may help patients with intestinal failure grow new and better gut

2012-10-16
URBANA – Adding the right prebiotic to the diets of pediatric patients with intestinal failure could replace intravenous feeding, says a new University of Illinois study. "When we fed the carbohydrate fructooligosacharide (FOS) as a prebiotic, the gut grew and increased in function," said Kelly A. Tappenden, a U of I professor of nutrition and gastrointestinal physiology. "The study showed that using the correct pre- and probiotic in combination could enhance these results even more." When FOS enters the intestines, bacteria convert it into butyrate, a short-chain fatty ...

Wake Forest Baptist researcher pieces together AML prognosis puzzle

2012-10-16
WINSTON-SALEM, N.C. – Oct. 15, 2012 – When patients suffering from Acute Myeloid Leukemia (AML) express high levels of the gene, MN1, an already aggressive leukemia is accelerated and shortens survival time. While that's a known fact, the mechanisms involved aren't well understood which is why a Wake Forest Baptist Medical Center researcher decided to take a closer look. Timothy S. Pardee, M.D., Ph.D., an assistant professor of hematology and oncology at Wake Forest Baptist, said that previous studies of AML have shown that when patients express high levels of the MN1 ...

Gold nanoparticle prostate cancer treatment found safe in dogs, MU study shows

2012-10-16
VIDEO: Scientists at the University of Missouri have proven that a new form of prostate cancer treatment that uses radioactive gold nanoparticles, and was developed at MU, is safe to use... Click here for more information. COLUMBIA, Mo. — Currently, large doses of chemotherapy are required when treating certain forms of cancer, resulting in toxic side effects. The chemicals enter the body and work to destroy or shrink the tumor, but also harm vital organs and drastically affect ...

Substandard, non-approved drugs put patients at risk

2012-10-16
The recent outbreak of meningitis in the US—and the subsequent deaths of 15 individuals—has renewed scrutiny on the contemporary practice of pharmacy compounding. The risks to patients, and associated liability risk to prescribing physicians, largely outweigh the benefits when the practice goes beyond the traditional, extemporaneous role, according to Sarah Sellers from q-Vigilance LLC and Wulf Utian from Case Western Reserve University in the US. Sellers and Utian's opinion piece appears online in the journal Drugs, published by Adis. There is a place for traditional ...

Study suggests how expanding waistlines may contribute to cancer

Study suggests how expanding waistlines may contribute to cancer
2012-10-16
Fat progenitor cells may contribute to cancer growth by fortifying the vessels that provide needed blood to tumors, according to preclinical research findings by investigators at The University of Texas Health Science Center at Houston (UTHealth). The results were reported in Cancer Research, a journal of the American Association for Cancer Research. Studies of groups of people have demonstrated a link between obesity and certain cancers; however, the physiological causes have not been identified. The World Health Organization reports that in 2008 there were more than ...

New guide helps providers make effective connection with senior patients

2012-10-16
"Communicating With Older Adults: An Evidence-Based Review of What Really Works," the latest report from The Gerontological Society of America (GSA), provides 40 pages of recommended guidelines for health care providers interacting with the fastest growing age segment of America's population. This publication is intended for physicians, nurses, pharmacists, biologists, psychologists, social workers, caregivers, economists, and health policy experts — anyone who seeks to have the best possible interactions with older patients. It was developed by GSA and supported by McNeil ...

Can vaccines be delivered via the lungs instead of by injection?

Can vaccines be delivered via the lungs instead of by injection?
2012-10-16
New Rochelle, NY, October 15, 2012—In addition to the obvious benefit of eliminating the need for an injection, new vaccine delivery methods via the lungs offer particular advantages for protecting against infectious agents that enter the body through the respiratory track. A comprehensive review article that presents the current status, challenges, and opportunities of pulmonary vaccine delivery is published in Journal of Aerosol Medicine and Pulmonary Drug Delivery, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free online on ...

Wide discrepancy in surveillance and control of infections in ICUs

2012-10-16
New York, NY (October 15, 2012) — Screening practices for multidrug-resistant organisms (MDROs) in intensive care units (ICUs) vary widely from hospital to hospital, according to a new study by researchers at Columbia University School of Nursing and published in the October 2012 issue of the American Journal of Infection Control. Researchers found that of the hospitals surveyed, a little more than half (59 percent) routinely screened for methicillin-resistant Staphylococcus aurea, or MRSA. Other potentially deadly MDROs were screened for far less frequently: vancomycin-resistant ...

Calling Miss Congeniality -- do attractive people have attractive traits and values?

2012-10-16
We've all been warned not to "judge a book by its cover," but inevitably we do it anyway. It's difficult to resist the temptation of assuming that a person's outward appearance reflects something meaningful about his or her inner personality. Indeed, research shows that people tend to perceive attractive adults as more social, successful, and well-adjusted than less attractive adults, a phenomenon that's been termed the "what is beautiful is good" stereotype. But could that really be true? Are physically attractive people really just as attractive on the inside as they ...

Language is shaped by brain's desire for clarity and ease

2012-10-16
VIDEO: Translation: "Referee statue pick up. " Above is one of the 80 animated video clips used to teach an artificial language to study participants. Cognitive scientists are just beginning to use... Click here for more information. Cognitive scientists have good news for linguistic purists terrified about the corruption of their mother tongue. Using an artificial language in a carefully controlled laboratory experiment, a team from the University of Rochester and ...

Montreal researchers shed new light on cancer risks associated with night work

2012-10-16
Night work can increase cancer risk in men, according to a new study published in the American Journal of Epidemiology by a research team from Centre INRS–Institut Armand-Frappier and Centre de recherche du Centre hospitalier de l'Université de Montréal. The study is one of the first in the world to provide evidence among men of a possible association between night work and the risk of prostate, colon, lung, bladder, rectal, and pancreatic cancer and non-Hodgkin's lymphoma. "Exposure to light at night can lead to a reduced production of the sleep hormone melatonin, inducing ...

Developing brain is source of stability and instability in adolescence

2012-10-16
The brain's "reward system," those brain circuits and structures that mediate the experience and pursuit of pleasure, figured prominently in several studies. The studies shed light on adolescents' ability to control impulsivity and think through problems; reveal physical changes in the "social brain;" document connections between early home life and brain function in adolescence; and examine the impact of diet on depressive-like behavior in rodents. Today's new findings show that: Adolescents can throw impulsivity out the window when big rewards are at stake. The ...

New tools for Alzheimer's may aid early diagnosis and treatment

2012-10-16
NEW ORLEANS — Curtailing the imminent rise in Alzheimer's disease (AD) will require early, accurate diagnostic tests and treatments, and researchers are closer to achieving these two goals. New findings in medical imaging, molecular analysis of neurological diseases, and development of treatments using mouse models were presented at Neuroscience 2012, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health. AD is the most common cause of dementia and currently affects 5 million people in the ...

New findings could help speed recovery, alleviate pain associated with spinal cord injury

2012-10-16
NEW ORLEANS — Research released today demonstrates how new scientific knowledge is driving innovative treatments for spinal cord injuries. Spinal cord damage is debilitating and life-altering, limiting or preventing movement and feeling for millions worldwide, and leading to chronic health conditions and pain. The new studies suggest potential therapies for managing the aftermath of pain and pressure sores, repairing nervous system damage, and speeding recovery. The findings were presented at Neuroscience 2012, the annual meeting of the Society for Neuroscience and the ...

Realizing the potential of stem cell therapy

2012-10-16
NEW ORLEANS — New animal studies provide additional support for investigating stem cell treatments for Parkinson's disease, head trauma, and dangerous heart problems that accompany spinal cord injury, according to research findings released today. The work, presented at Neuroscience 2012, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health, shows scientists making progress toward using stem cell therapies to repair neurological damage. The studies focused on using stem cells to produce neurons ...

Personalized genomic medicine: How much can it really empower patients?

2012-10-16
(Garrison, NY) Personalized genomic medicine is hailed as a revolution that will empower patients to take control of their own health care, but it could end up taking control away from patients and limiting their treatment choices, concludes an article in the Hastings Center Report. A commentary responding to the article, by the editorial director of Health and Family at Consumer Reports, also appears in the journal. Genomic science provides two categories of data, the authors write: pharmacogenomic information and genomic susceptibility information. Pharmacogenomic ...

NASA sees mostly moderate rainfall in Tropical Storm Maria

NASA sees mostly moderate rainfall in Tropical Storm Maria
2012-10-16
Tropical Storm Maria was born in the western North Pacific Ocean and has a large area of moderate rainfall, as NASA's TRMM satellite revealed today, Oct. 15. NASA's TRMM satellite noticed that most of Maria's rainfall was occurring northeast of the storm's center. Maria is the twenty-third tropical cyclone of the western North Pacific season. When NASA's Tropical Rainfall Measuring Mission (TRMM) satellite passed over Tropical Storm Maria on Oct. 15 at 1329 UTC (9:29 a.m. EDT) light to moderate rainfall was occurring northeast of the center and falling at a rate between ...

NASA watching Hurricane Paul, warnings up for Baja California

NASA watching Hurricane Paul, warnings up for Baja California
2012-10-16
Tropical cyclones seem to love forming over weekends, Rafael formed over the weekend in the Atlantic, Anais in the Southern Indian Ocean and Hurricane Paul in the eastern Pacific Ocean. NASA's Terra satellite kept on top of Paul, however, and provided forecasters with a visible look at the newborn storm. Paul formed on Oct. 13 at 5 p.m. EDT about 660 miles (1,065 km) south-southwest of the southern tip of Baja California, near 14.0 North and 113.6 West. The Moderate Resolution Imaging Spectroradiometer (MODIS) instrument aboard NASA's Terra satellite captured a visible ...

NASA eyes Tropical Storm Rafael battering the Leeward Islands

NASA eyes Tropical Storm Rafael battering the Leeward Islands
2012-10-16
While the Leeward Islands continue to get battered by Tropical Storm Rafael, a Tropical Storm Watch is posted for Bermuda as Rafael continues to move through the eastern Atlantic Ocean. NASA's Aqua satellite passed over Rafael on Oct. 14 and noticed the bulk of showers and thunderstorms were being pushed north and east of the storm's center. The Moderate Resolution Imaging Spectroradiometer (MODIS) instrument aboard NASA's Aqua satellite captured a visible image of Tropical Storm Rafael in the Atlantic Ocean on Oct. 14, 2012 at 1720 UTC (1:20 p.m. EDT). The image clearly ...

NASA sees Tropical Cyclone Anais headed near La Reunion Island

NASA sees Tropical Cyclone Anais headed near La Reunion Island
2012-10-16
Tropical Cyclone Anais, the first tropical cyclone of the Southern Indian Ocean's tropical cyclone season, has strengthened over the weekend of Oct. 13 and 14 and by Oct. 15, the storm was packing sustained winds near 100 knots (115 mph/185 kph). The Moderate Resolution Imaging Spectroradiometer (MODIS) instrument aboard NASA's Aqua satellite captured a visible image of Tropical Cyclone Anais off Madagascar on Oct. 15 at 0940 UTC (5:40 a.m. EDT) and revealed an eye. Multi-spectral satellite imagery showed that convection has continued to decrease around Anais' ragged ...

NASA satellite reveals some strong rainfall in meandering Typhoon Prapiroon

NASA satellite reveals some strong rainfall in meandering Typhoon Prapiroon
2012-10-16
Typhoon Prapiroon has been meandering in the western North Pacific Ocean over the weekend of Oct. 13 and 14, and NASA's TRMM satellite was able to identify where the strongest rainfall was occurring in the storm. The Tropical Rainfall Measuring Mission (TRMM) satellite passed directly above weakening Typhoon Prapiroon in the western Pacific Ocean on October 12, 2012 at 0741 UTC (3:41 a.m. EDT). At that time, Typhoon Prapiroon was a powerful category two typhoon on the Saffir-Simpson scale with winds slightly less than 95 knots (~109 mph). A 3-D image of the storm was ...

New rapid and point of care hepatitis C tests could be global game changers

New rapid and point of care hepatitis C tests could be global game changers
2012-10-16
Montreal October 15, 2012 – Timely screening and diagnosis is critical to the success of new treatments and ultimately to the survival of hepatitis C patients. A new study led by the Research Institute of the McGill University Health Centre (RI MUHC) is the first to show that hepatitis C rapid and point of care tests with a quick turnaround time are highly accurate and reliable as conventional first-line laboratory tests. This head-to-head analysis, published in the current issue of the Annals of Internal Medicine, will lead to changes in screening practices and ultimately ...
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