DURHAM, N.C. -- Advanced high-speed gene-sequencing has been used in the clinical setting to find diagnoses for seven children out of a dozen who were experiencing developmental delays and congenital abnormalities for mysterious reasons. "I thought if we could obtain even a couple of relatively secure diagnoses out of the 12 patients, that would prove the value of deploying sequencing approaches systematically in patients with unknown but apparently genetic conditions," said David Goldstein, Ph.D., director of the Duke Center for Human Genome Variation and professor ...

San Diego, CA, May 8, 2012 – As populations move even further away from urban centers, more people spend longer hours behind the wheel on their way to and from work. While sedentary behavior is known to have adverse effects on cardiovascular and metabolic health, the impact of long commutes by automobile are less understood. A new study has found that greater commuting distances are associated with decreased cardiorespiratory fitness (CRF), increased weight, and other indicators of metabolic risk. The results are published in the June issue of American Journal of Preventive ...

Fort Lauderdale, FL, USA and Lausanne, Switzerland, May 8, 2012 – Gene Signal, a company focused on developing innovative drugs to manage angiogenesis based conditions, today announced that positive data from a study of aganirsen (GS-101, eye drops) in a nonhuman primate model of choroidal neovascularization has been presented at the 2012 ARVO Annual Meeting in Fort Lauderdale, Florida. Topical administration of aganirsen was found to inhibit neovascular growth and leakage in this model and strongly suggests a role for the drug candidate in human retinal neovascular diseases ...

Researchers at Auburn University have reported the discovery a new trapdoor spider species from a well-developed housing subdivision in the heart of the city of Auburn, Alabama. Myrmekiaphila tigris, affectionately referred to as the Auburn Tiger Trapdoor spider, is named in honor of Auburn University's costumed Tiger mascot, Aubie. The research team, directed by Biological Sciences professor Jason Bond, lead investigator and director of the Auburn University Museum of Natural History, and Charles Ray, a research fellow in the Department of Entomology & Plant Pathology, ...

BedBug Chasers, a World Class provider of heat remediation services and manufacturer of US made bed bug heat remediation equipment is franchising its service business. The business features a low entry cost, is a 100% chemical free and Green enterprise, and will be offered through the BedBug Chaser Franchise Corporation. The cornerstones of this booming franchise program features exclusive access to the patented BedBug Chaser heaters, the BedBug Chasers nationwide rental fleet and training on the BedBug Chasers propriety process. The BedBug Chaser heaters have proven ...

University of British Columbia researchers have found a potential way to develop universal flu vaccines and eliminate the need for seasonal flu vaccinations. Each year, seasonal influenza causes serious illnesses in three to five million people and 200,000 to 500,000 deaths. The 2009 H1N1 pandemic killed more than 14,000 people worldwide. Meanwhile, public health and bioterrorism concerns are heightened by new mutations of the H5N1 "bird flu" virus, published last week by the journal Nature, that could facilitate infection among mammals and humans. Led by Prof. John ...

Creatage, a full service marketing agency has started developing specialized marketing plans and tactics for vineyards and the wine making community. According to Creatage's spokesperson, the agency has been helping these industries in capturing and retaining audiences in new and interesting ways through wine marketing tactics that have recently seen great success in this area. To take advantage of this new service you simply need to fill out a contact from on their company's website and a representative will discuss the next steps to see how Creatage can develop a customize ...

Stubb's Legendary Kitchen, makers of all-natural, premium Stubb's Bar-B-Q sauces, rubs and marinades, is expanding its product line throughout 2012 to include a new sweet and spicy sauce flavor, new injectable marinades and a reformulated premium spice rub line. The items reflect some of 2012's top food trends: --Sweet and spicy: Combining two favorite tastes in one delicious sauce, Stubb's Sweet Heat is a combination of molasses and brown sugar with a touch of chipotle. Sweet Heat is the newest addition to the Stubb's all-natural sauce lineup that includes Original, ...

Los Gatos Research (LGR), the leader in precision trace gas analyzers, has received an order for five more of the company's unique N2O/CO (nitrous oxide/carbon monoxide) trace gas analyzers from the California Air Resources Board (CARB). These particular instruments (part of LGR's acclaimed Enhanced Performance series) deliver extremely stringent performance specifications, including better than fifty parts-per-trillion measurement precision, ultrahigh long-term stability, and over four decades of dynamic range for both gases. Furthermore, the instruments specifications ...

Aneesoft Co., Ltd. a leading developer of multimedia-processing software, launched a new version of its flagship products Aneesoft Total Media Converter 3.5.0.0. The newest version is running more stable on Windows 7 OS, after fixing the crash problem while editing videos and some minor bugs. The converter software also features support for outputting 1080P videos for the latest mobile devices, the new iPad, Apple TV, iPhone 4S, Kindle Fire etc. Aneesoft Total Media Converter is comprehensive video converter software designed to convert DVDs to video files; convert videos, ...

Summer of 2011 left Doug Sabbag and his wife a little more shaken up than planned. The plan was to leave Boston aboard their 50ft ketch (Triumph) and head for Europe. Unfortunately, just southeast of Nova Scotia, Doug and his wife had to be rescued. First-hand experience taught them about the mistakes they made along the way and more importantly when they should have called for assistance versus when the original call was made. Doug will share with us what went wrong on his trip, solutions he came up with, and what happened during his rescue. Since four years old, Doug ...

The Greater Raleigh-Durham Chapter 105 of the Institute of Real Estate Management (IREM) has again received high honors in IREM's Chapter Star Recognition Program. The Chapter was formally recognized for achieving Five Star Status at the IREM Awards Event and Dinner at this year's Leadership and Legislative Summit held on April 16th in Washington, DC. IREM Chapter 105, which serves the greater Raleigh and Durham area, was recognized for a variety of initiatives it undertook in 2011, while under the leadership of Chapter Immediate Past President, Jason Stowe, CPM. ...

The documentary Ancient Tomorrow will follow a team of researchers on an extreme expedition through the South American Andes to investigate the mysteries surrounding an ancient "non-polluting" wireless energy technology. After six years of research, chemical engineer JJ Yosh will head the sixty-day expedition from Bolivia to Peru on May 15. The team's intense outdoor adventure will include climbing the Cordillera Real and Blanca mountain ranges, diving beneath Lake Titicaca, trekking the Machu Picchu jungles, and rappelling into unexplored caverns while investigating ...

Local pest control company, Specialized Pest Patrol, has reported numerous phone calls from homeowners who don't feel safe with the do-it-yourself solution of yellow jacket nest removal. "For your personal safety, it is recommended to hire a professional. If one yellow jacket stings you, the sting gives off pheromones which can create a chain reaction causing the entire colony to come after you," warns Rob Smith, part of the father-son team of Specialized Pest Patrol. While flying insects overall are harmless, yellow jackets are by far the most troublesome ...

Zodiac Baby, a trendy bath line amongst parents, teams up with the fastest growing flash sales website, Fab.com for a three-day sale starting today. The astrologically inspired collection, designed for children and their parents alike, is available on Fab.com May 2, 7:00 p.m. EST through May 9, 6:59 p.m. EST. Members of Fab.com will receive 38 % off all Zodiac Baby products. Inspired by the belief that astrological signs carry particular traits we eventually develop, founder and creator Teny Kureghian, dreamed of creating a product specifically designed for a baby's ...

Shelley Hitz was recently invited by Nick Boork to give a live "Self Publishing Seminar" at Grace Christian Church in Sterling Heights, Michigan. With her intuitive thinking, she had all four sessions professionally videotaped, and has now made them available to the public with the hope of helping even more authors get published and market their books. After the seminar the professional speaker had this to say, "I've done a lot of online webinars, but this was my first live self publishing seminar and I loved it. I think it was my best seminar yet." The ...

Does the amount of your Long Beach home insurance coverage reflect the value of your property? According to a February 2012 survey from the National Association of Insurance Commissioners (NAIC), 59 percent of American homeowners have not made a list of their possessions, 48 percent do not have receipts for their property, 27 percent do not have photos, and 28 percent do not have a back-up copy of the inventory safely stored outside the home. The survey also revealed that 59 percent of homeowners with inventories have not updated them in over a year. Why is this study ...

Tile flooring retailer BuyTile, located at http://www.BuyTile.com, is currently spotlighting its extensive inventory of dual interior and exterior tiles in time for the warm weather and homeowners' outdoor design projects. The merchant, which stocks thousands of top-quality ceramic, porcelain, and glass tiles, receives its products directly from the original manufacturers, allowing it to maintain its accessible and economical pricing system. Consisting of natural stone, pebble mosaic, and porcelain, its diverse outside-friendly flooring collection helps give consumers the ...

According to the National Center for Family & Marriage Research at Bowling Green State University, divorce in the U.S. is declining overall -- with one glaring exception: the divorce rate for those 50 years and older has doubled in the past 20 years. Experts have dubbed the trend "grey divorce," and see it in keeping with other ways that the Baby Boomer generation has redefined aging. Those considering divorce later in life should be aware of some of the ways that divorce will differ from younger couples. Children Many Baby Boomers' children are already ...

There are many available ways to lower the amount of income taxes an individual owes including filing status, deductions, dependents and credits. The filing status resulting in the lowest amount of taxes owed is "Married Filing Jointly." According to a recent CNN report, this filing status can save approximately $6,000 per year. The taxpayers must be married in order to take advantage of the "married filing jointly" filing status. However, this option is not available to same-sex couples. Because of federal and state laws preventing same-sex couples ...

The Internal Revenue Service requires that anyone receiving income from any source must file a tax return each year, with limited exceptions. If an individual does not file an income tax return, the IRS will file one for them and then send that individual the bill of the taxes owed. At first, this sounds somewhat advantageous to have the service itself prepare and file taxes, but this process has its drawbacks. The IRS prepared-filing is in no way a good substitute for a return a taxpayer prepares and sends personally. These "ghost returns" are based only on ...

After creating an estate plan, it can be easy to set it aside without a second thought. However, it is important to revisit your estate plan periodically to check for hidden errors or changes in circumstance that could undermine your intent. The following examples are just a few of the numerous estate planning mistakes that can occur every day. Naming the Wrong Beneficiary on Your Retirement Plan Many people make the mistake of forgetting or neglecting to update the beneficiary designations on their retirement plans as their circumstances change. For instance, young ...

People should know their rights, and that is especially true of individuals who have domestic violence charges alleged against them. Allegations of domestic violence can result in criminal charges and can also affect decisions in family court. An important part of understanding one's rights is knowing how crimes in New York are defined. Recently, state legislators proposed changes to New York's domestic violence laws that would make the laws tougher. New York state legislators recently proposed changes to the state's domestic violence laws that would make it a felony ...

Benjamin Franklin once wrote in a letter, "n this world nothing can be said to be certain, except death and taxes." Franklin's words capture the distain many people hold for paying taxes. Few people appreciate having to file income tax returns with the federal government, but people who fail to file returns run the risk of a variety of punishments. However, people can mitigate some of the damage by filing past due returns. Consequences of Failing to File Returns People who do not file income tax returns open themselves up to the possibility of several penalties, ...

The IRS may choose to file a lien on a person's property who has failed to pay on a tax obligation. A tax lien is an encumbrance on the debtor's property that secures the government's interest in the property for the amount of the debt. Those having tax troubles should be aware of the effects a tax lien, particularly how tax liens affect homes, and how to discharge a tax lien. Effects of a Tax Lien After the IRS determines that a person owes taxes and has not paid, the IRS notifies the person of his or her obligation. If the person still does not pay, the IRS will ...