JUPITER, FL, July 5, 2012 – Scientists from the Florida campus of The Scripps Research Institute have identified a series of intricate biochemical steps that lead to the successful production of proteins, the basic working units of any cell. The study, which appears in the July 6, 2012 edition of the journal Cell, sheds light on the assembly of a structure called the ribosome, a large and complex protein-producing machine inside all living cells. Ribosomes are the targets of many commercially used antibiotics and represent a promising area of research because of the ...

Feeling full involves more than just the uncomfortable sensation that your waistband is getting tight. Investigators reporting online on July 5th in the Cell Press journal Cell have now mapped out the signals that travel between your gut and your brain to generate the feeling of satiety after eating a protein-rich meal. Understanding this back and forth loop between the brain and gut may pave the way for future approaches in the treatment and/or prevention of obesity. Food intake can be modulated through mu-opioid receptors (MORs, which also bind morphine) on nerves found ...

Most people call it the "art" of persuasion, but public health researchers at the University of Southern California (USC) are trying to pinpoint the "science" behind social influence. They hope a better understanding of human interactions — both face-to-face and online — can help prevent disease and promote general health. Whether the goal is to curb smoking at a local school or to reduce the spread of sexually transmitted diseases within a community, it is important to understand the social structure of the group and the dynamics of influence at play, says Thomas W. ...

MELBOURNE, FLA.—Climate change drove coral reefs to a total ecosystem collapse lasting thousands of years, according to a paper published this week in Science. The paper shows how natural climatic shifts stopped reef growth in the eastern Pacific for 2,500 years. The reef shutdown, which began 4,000 years ago, corresponds to a period of dramatic swings in the El Niño–Southern Oscillation (ENSO). "As humans continue to pump greenhouse gases into the atmosphere, the climate is once again on the threshold of a new regime, with dire consequences for reef ecosystems unless we ...

VIDEO: A blood clot within a mouse artery disappears following the injection of a clot-busting, shear-activated nanotherapeutic. The bright areas are fluorescent-labeled platelets. Click here for more information. Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have developed a novel biomimetic strategy that delivers life-saving nanotherapeutics directly to obstructed blood vessels, dissolving blood clots before they cause ...

DURHAM, N.C. -- Although many areas of the human brain are devoted to social tasks like detecting another person nearby, a new study has found that one small region carries information only for decisions during social interactions. Specifically, the area is active when we encounter a worthy opponent and decide whether to deceive them. A brain imaging study conducted by researchers at the Duke Center for Interdisciplinary Decision Science (D-CIDES) put human subjects through a functional MRI brain scan while playing a simplified game of poker against a computer and human ...

The discovery is an important step toward therapies that aim to repair the brain not by introducing new stem cells but rather by spurring those that are already present into action, says the study's lead author Freda Miller of the University of Toronto-affiliated Hospital for Sick Children. The fact that it's a drug that is so widely used and so safe makes the news all that much better. Earlier work by Miller's team highlighted a pathway known as aPKC-CBP for its essential role in telling neural stem cells where and when to differentiate into mature neurons. As it happened, ...

SAN FRANCISCO, CA--July 5, 2012--Scientists at the Gladstone Institutes have discovered that environmental factors critically influence the growth of a type of stem cell--called an iPS cell--that is derived from adult skin cells. This discovery offers newfound understanding of how these cells form, while also advancing science closer to stem cell-based therapies to combat disease. Researchers in the laboratory of Gladstone Senior Investigator Shinya Yamanaka, MD, PhD, have for the first time shown that protein factors released by other cells affect the "reprogramming" ...

On a recent expedition to the inhospitable North Atlantic Ocean, scientists at the University of Washington and collaborators studying the annual growth of tiny plants were stumped to discover that the plankton had started growing before the sun had a chance to offer the light they need for their growth spurt. For decades, scientists have known that springtime brings the longer days and calmer seas that force phytoplankton near the surface, where they get the sunlight they need to flourish. But in research results published this week in the journal Science, scientists ...

Aneurysm screening for men aged over 65 is cost effective and rescreening those at highest risk, at least once, should be considered, suggests a study published on bmj.com today. Abdominal aortic aneurysms (caused by ballooning of the artery wall) usually occur in men aged between 65 and 75 years old and are more common among smokers. If the artery wall ruptures, the risk of death is high, but aneurysms at risk of rupture can be detected by screening and surgically repaired. One-off screening for men aged over 65 is known to be cost effective and national screening ...

A group of US researchers has produced a robotic set of legs which they believe is the first to fully model walking in a biologically accurate manner. The neural architecture, musculoskeletal architecture and sensory feedback pathways in humans have been simplified and built into the robot, giving it a remarkably human-like walking gait that can be viewed in this video - http://www.youtube.com/watch?v=MnD7LqisBhM&feature=youtu.be. The biological accuracy of this robot, which has been presented today, Friday 6 July, in IOP Publishing's Journal of Neural Engineering, ...

Ottawa (July 5th, 2012) – An international expert panel has assessed that decisions regarding science funding and performance can't be determined by metrics alone. A combination of performance indicators and expert judgment are the best formula for determining how to allocate science funding. The Natural Sciences and Engineering Research Council of Canada (NSERC) spends approximately one billion dollars a year on scientific research. Over one-third of that goes directly to support discovery research through its flagship Discovery Grants Program (DGP). However, concerns ...

In secrecy, the "apps" forward private data to a third party. Computer scientists from Saarbrücken have developed a new approach to prevent this data abuse. They can put a stop to the data theft through the app "SRT AppGuard". The chief attraction: For the protection to work, it is not necessary to identify the suspicious programs in advance, nor must the operating system be changed. Instead, the freely available app attacks the program code of the digital spies. "My smartphone knows everything about me, starting with my name, my phone number, my e-mail address, my interests, ...

The earth is shaken daily by strong earthquakes recorded by a number of seismic stations worldwide. Tectonic tremor, however, is a new type of seismic signal that seismologist started studying only within the last few years. Tremor is less hazardous than earthquakes and occurs at greater depth. The link between tremor and earthquakes may provide clues about the more destructive earthquakes that occur at shallower depths. Geophysicists of Karlsruhe Institute of Technology (KIT) collected seismic data of tectonic tremor in California. These data are now being evaluated in ...

The immunosuppressive drug fingolimod (trade name: Gilenya®) is approved for the treatment of highly-active relapsing-remitting multiple sclerosis (RRMS) in adults. In an early benefit assessment pursuant to "Act on the Reform of the Market for Medicinal Products" (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) assessed whether fingolimod offers an added benefit compared with the present standard therapy. According to the findings of the assessment, patients with a rapidly progressive and severe course of disease who take fingolimod experience ...

Over the past year, some news reports have questioned the long-term viability and popularity of daily deal companies, but the industry shows no evidence of slowing down, according to a new study from Rice University. In the study, "How Businesses Fare With Daily Deals As They Gain Experience: A Multi-Time Period Study of Daily Deal Performance," Utpal Dholakia examines performance of daily deals using survey data from 641 small- and medium-sized businesses obtained at three time periods: April-May 2011, October 2011, and May 2012. Dholakia is a professor of management ...

Around seven percent of adults suffer from an intolerance to wine. This is the result of a survey presented by Peter Wigand and co-authors in the current edition of Deutsches Ärzteblatt International (Dtsch Arztelb Int 2012; 109 (25): 437-44). The authors evaluated 948 questionnaires that were returned from the 4000 sent out to randomly selected people between the ages of 20 and 69 years. They found that women (8.9%) were more often affected by an intolerance to wine than men (5.2%). The most commonly reported reactions included flushed and itchy skin and a runny nose. ...

EAST LANSING, Mich. — The stock market should be regulated only during times of extraordinary financial disruptions when speculators can destroy healthy businesses, according to a new study led by a Michigan State University scholar. The study, in the Journal of Financial Economics, is one of the first to suggest when the U.S. Securities and Exchange Commission should get involved in the market. The answer: rarely. The SEC should step in only when outside financial disruptions make it impossible for large shareholders to fend off "short sellers" – or speculators betting ...

Does being an intense mother make women unhappy? According to a new study by Kathryn Rizzo and colleagues, from the University of Mary Washington in the US, women who believe in intensive parenting - i.e., that women are better parents than men, that mothering should be child-centred, and that children should be considered sacred and are fulfilling to parents - are more likely to have negative mental health outcomes. The work is published online in Springer's Journal of Child and Family Studies. Parenting can be quite challenging and requires wide-ranging skills and expertise ...

Using piezoelectric materials, researchers have replicated the muscle motion of the human eye to control camera systems in a way designed to improve the operation of robots. This new muscle-like action could help make robotic tools safer and more effective for MRI-guided surgery and robotic rehabilitation. Key to the new control system is a piezoelectric cellular actuator that uses a novel biologically inspired technology that will allow a robot eye to move more like a real eye. This will be useful for research studies on human eye movement as well as making video feeds ...

When evaluating job applicants, employers want to be sure that they choose the right person for the job. Many employers, from consulting firms to federal agencies, will ask prospective employees to complete extensive tests and questionnaires to get a better sense of what those employees might be like in an office setting. But new research published in the July 2012 issue of Perspectives on Psychological Science, a journal of the Association for Psychological Science, suggests that a different factor – employee interests – may be a better way to predict who will perform ...

Obesity increases the risk of acute kidney injury (AKI) following cardiac surgery, according to a Vanderbilt study published in the Journal of the American Society of Nephrology. Considered common after cardiac surgery, AKI represents a fivefold increase in mortality risk within 30 days after the procedure and is associated with longer hospital stays and a range of complications. The study, led by anesthesiologist Frederic T. (Josh) Billings IV, M.D., M.Sc., followed a sample of 455 cardiac surgery patients at Vanderbilt University Hospital and Brigham and Women's Hospital ...

MANHATTAN, Kan. -- Many patients seem to ignore prescription drug warning labels with instructions that are critical for safe and effective use, according to a study by a Kansas State University researcher working with scientists at Michigan State University. Consumers, particularly older ones, often overlook prescription drug warning labels in part because the labels fail to attract attention, said Nora Bello, an assistant professor of statistics at Kansas State University. Bello helped investigate the effectiveness of prescription drug warning labels to convey drug ...

Groundbreaking new research in the field of "evolutionary analysis in law" not only provides additional evidence that chimpanzees share the controversial human psychological trait known as the endowment effect – which in humans has implications for law – but also shows the effect can be turned on or off for single objects, depending on their immediate situational usefulness. In humans, the endowment effect causes people to consider an item they have just come to possess as higher in value than the maximum price they would have paid to acquire it just a moment before. ...

On this July 4th week, U.S. beachgoers are thronging their way to seaside resorts and parks to celebrate with holiday fireworks. But across the horizon and miles out to sea toward the north, the Atlantic Ocean's own spring and summer ritual unfolds. It entails the blooming of countless microscopic plants, or phytoplankton. In what's known as the North Atlantic Bloom, an immense number of phytoplankton burst into existence, first "greening," then "whitening" the sea as one or more species take the place of others. What turns on this huge bloom, what starts these ocean ...