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Protein and microRNA block cellular transition vital to metastasis

Protein and microRNA block cellular transition vital to metastasis
2011-02-28
HOUSTON - Like a bounty hunter returning escapees to custody, a cancer-fighting gene converts organ cells that change into highly mobile stem cells back to their original, stationary state, researchers report online at Nature Cell Biology. This newly discovered activity of the p53 gene offers a potential avenue of attack on breast cancer stem cells thought to play a central role in progression and spread of the disease, according to scientists at The University of Texas MD Anderson Cancer Center. Long known for monitoring DNA damage and forcing defective cells to kill ...

Overfertilizing corn undermines ethanol

2011-02-28
Rice University scientists and their colleagues have found that when growing corn crops for ethanol, more means less. A new paper in today's online edition of the American Chemical Society's journal Environmental Science and Technology shows how farmers can save money on fertilizer while they improve their production of feedstock for ethanol and alleviate damage to the environment. The research has implications for an industry that has grown dramatically in recent years to satisfy America's need for energy while trying to cut the nation's reliance on fossil fuels. The ...

Successful tech transfer leads to more Hawaiian exports

2011-02-28
Hawaii growers can now export more fruits and vegetables to the U.S. mainland, thanks to technology advanced by U.S. Department of Agriculture (USDA) scientists and cooperators. Delicious tropical fruits and vegetables such as papaya, rambutan, longan, dragon fruit and purple-fleshed sweet potato are gaining popularity in the continental United States. But just five years ago, it would have been difficult to find these tropical delicacies in grocery stores. That's because strict quarantine restrictions and phytosanitary measures are in place to ensure agricultural pests ...

Tweeting teenage songbirds reveal impact of social cues on learning

2011-02-28
In a finding that once again displays the power of the female, UCSF neuroscientists have discovered that teenage male songbirds, still working to perfect their song, improve their performance in the presence of a female bird. The finding sheds light on how social cues can impact the process of learning, the researchers said, and, specifically, could offer insights into the way humans learn speech and other motor skills. It also could inform strategies for rehabilitating people with motor disorders or brain injuries. The study was reported in a recent early online edition ...

Radio-guided surgery a safe and simple way to remove potentially cancerous nodules in the lung

2011-02-28
Using tiny spheres of radioactive liquid to guide surgeons as they remove potentially cancerous material in the lungs is safe and more effective than other techniques, Italian researchers report at the European Multidisciplinary Conference in Thoracic Oncology (EMCTO), 24-26 February 2011, Lugano, Switzerland. Dr Luca Bertolaccini, Dr Alberto Terzi and colleagues from Santa Croce e Carle Hospital in Cuneo, Italy, studied a technique known as radio-guided surgery in 19 patients. Each of the patients had been found to have 'single pulmonary nodules' in their lungs. Single ...

Erlotinib effective and with fewer side-effects after first-line treatment

2011-02-28
The targeted cancer drug erlotinib has comparable efficacy to chemotherapy, and is better tolerated, in hard-to-treat cases where a patient's cancer has progressed quickly after treatment with first-line therapy, the results of a new phase III trial show. Dr Tudor Ciuleanu from the Institute of Oncology Ion Chiricuta, Cluj-Napoca, Romania, reported this finding from the international TITAN study at the European Multidisciplinary Conference in Thoracic Oncology (EMCTO), 24-26 February 2011, Lugano, Switzerland. "The TITAN study is the first trial to evaluate whether ...

Canada's role grows amid looming world water shortages in some places, more flooding in others

Canadas role grows amid looming world water shortages in some places, more flooding in others
2011-02-28
Famed especially for the excellence of its peacekeepers and ice hockey players, Canada's water experts are now increasingly needed to help countries elsewhere brace for drought, flood and unsafe water problems looming on a 15 to 20 year horizon. Within a single generation, recent studies show, water demand in many countries will exceed supply by an estimated 40%, with one-third of humanity having half the water required for life's basics. In flood-prone places, meanwhile, catastrophic flood events normally expected once a century - similar to those recently witnessed ...

Advanced degrees add up to lower blood pressure

2011-02-28
PROVIDENCE, R.I. [Brown University] — Freshmen on the eve of finals and graduate students staring down a thesis committee may not feel this way, but the privilege of obtaining an advanced education correlates with decades of lower blood pressure, according to a study led by a public health researcher at Brown University. The benefit appears to be greater for women than for men. Eric Loucks, assistant professor of community health, says the analysis of nearly 4,000 patient records from the 30-year Framingham Offspring Study may help explain a widely documented association ...

Immune molecule regulates brain connections

2011-02-28
The number of connections between nerve cells in the brain can be regulated by an immune system molecule, according to a new study from UC Davis. The research, published Feb. 27 in the journal Nature Neuroscience, reveals a potential link between immunity, infectious disease and conditions such as schizophrenia or autism. Schizophrenia, autism and other disorders are associated with changes in connectivity in the brain, said Kimberley McAllister, associate professor in the Center for Neuroscience and Departments of Neurology and Neurobiology, Physiology and Behavior ...

First aid for the under 5s

2011-02-28
One of the reasons often given by people for not attempting first aid in emergency situations is a lack of confidence and a fear of doing more harm than good. Yet a Norwegian study on four and five year olds published in BioMed Central's open access journal Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine shows that even young children are able to learn and perform basic first aid. Pre-school children at a kindergarten in Bergen, Norway, were taught first aid using the 'five-finger-rule' system: look at the person, talk to them, touch them to try ...

How education can save your life

2011-02-28
It is known that education decreases the incidence of cardiovascular disease. New research published in BioMed Central's open access journal BMC Public Health demonstrates that education is also correlated with lower blood pressure and a decrease in other factors which influence health such as alcohol, smoking and weight gain. Taking their data from The Framingham Offspring Study researchers followed 3890 people, for 30 years, monitoring their medical history, how long they stayed in education, and their levels of coronary heart disease. Educated men (greater than 17 ...

Canadian researchers first worldwide to generate pluripotent stem cells from horses

2011-02-28
In a world first, pluripotent stem cells have been generated from horses by a team of researchers led by Dr. Andras Nagy at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital and Dr. Lawrence Smith at the University of Montreal's Faculty of Veterinary Science. The findings will help enable new stem-cell based regenerative therapies in veterinary medicine, and because horses' muscle and tendon systems are similar to our own, aid the development of preclinical models leading to human applications. The study was published in the February 28 issue of the leading ...

Fish oil fights weight loss due to chemotherapy

2011-02-28
A new analysis has found that supplementing the diet with fish oil may prevent muscle and weight loss that commonly occurs in cancer patients who undergo chemotherapy. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study indicates that fish oil may help combat cancer-related malnutrition. Chemotherapy can cause cancer patients to lose muscle mass and become malnourished, leading to fatigue, a decreased quality of life, an inability to receive necessary treatments, and shorter survival. Researchers suspect that supplementing ...

Gene fuelled transporter causes breast cancer cells to self-destruct

2011-02-28
Scientists at Queen's University Belfast have shown that they can deliver a gene directly into breast cancer cells causing them to self-destruct, using an innovative, miniscule gene transport system, according to research published today (28 February) in the International Journal of Pharmaceutics. Using a transport system called a Designer Biomimetic Vector (DBV), Dr Helen McCarthy, from Queen's School of Pharmacy, funded by Breast Cancer Campaign, packaged a gene into a nanoparticle 400 times smaller than the width of a human hair, allowing it to be delivered straight ...

Hearing loss rate in older adults climbs to more than 60 percent in national survey

2011-02-28
Nearly two-thirds of Americans age 70 and older have hearing loss, but those who are of black race seem to have a protective effect against this loss, according to a new study led by Johns Hopkins and National Institute on Aging researchers. These findings, published online Feb. 28 in the Journal of Gerontology: Medical Sciences, provide what is believed to be the first nationally representative survey in older adults on this often ignored and underreported condition. Contrary to the view that hearing loss is of only minor importance in old age, study leader Frank Lin, ...

University of Miami scientists track great hammerhead shark migration

University of Miami scientists track great hammerhead shark migration
2011-02-28
MIAMI – Feb 28, 2011 – A study led by scientists at the University of Miami (UM) Rosenstiel School of Marine & Atmospheric Science details the first scientific research to successfully track a great hammerhead shark using satellite tag technology. Rosenstiel Schhol Research Assistant Professor Neil Hammershlag and colleagues tracked one of the nomadic sharks for 62 days to uncover its northeast journey from the coast of South Florida to the middle of the Atlantic off the coast of New Jersey. The straight line point-to-point distance of 1,200 kilometers (745 miles) represents ...

Forsyth team gains new insight on childhood dental disease

2011-02-28
Researchers at The Forsyth Institute have made a significant discovery about the nature of childhood dental disease. The scientific studies led by Anne Tanner, BDS, Ph.D., identified a new pathogen connected to severe early childhood caries (cavities). This bacterium, Scardovia wiggsiae, was present in the mouths of children with severe early childhood caries when other known pathogens such as Streptococcus mutans were not detected. This research may offer the potential to intervene and halt the progression of disease. Early childhood caries, ECC, is the most common chronic ...

This microbe's for you: Brewery waste becomes scientific fodder for producing liquid biofuels

2011-02-28
ITHACA, N.Y. – Gaining new insight into how efficiently the microbes in large bioreactors produce methane from brewery waste, Cornell scientists hope to use their new knowledge to shape these microbial communities to produce liquid biofuels and other useful products. The scientists Largus T. Angenent, associate professor of biological and environmental engineering, and the first author and research associate Jeffrey J. Werner, published "Bacterial Community Structures Are Unique and Resilient in Full-Scale Bioenergy Systems" (Proceedings of the National Academy of Sciences, ...

Increasing processor efficiency by 'shutting off the lights'

Increasing processor efficiency by shutting off the lights
2011-02-28
Cambridge, Mass. - February 28, 2011 - There was a time when a laptop could weigh 10 pounds and still sell—a time when a cell phone was larger than a pocket—and a time when an iPod only played music. Today's consumers expect mobile devices that are increasingly small, yet ever-more powerful. All the bells and whistles, however, suck up energy, and a phone that lasts only 4 hours because it's also a GPS device is only so much use. To promote energy-efficient multitasking, Harvard graduate student Wonyoung Kim has developed and demonstrated a new device with the potential ...

Foster parents receive more support than kinship caregivers, UT Southwestern study finds

2011-02-28
DALLAS – Feb. 28, 2011 – Children who are placed with a relative because of mistreatment at home fare better in some areas than those placed in foster care, but they may have a higher risk of substance use and teenage pregnancy. The findings by researchers at UT Southwestern Medical Center, which appear in the February issue of the Archives of Pediatrics and Adolescent Medicine, also show that relatives – also known as kinship caregivers – receive fewer support services than foster parents. Dr. Glenn Flores, professor of pediatrics at UT Southwestern and senior author ...

A Re-cycled Concept Improved: Urban Bike Transport Revival On Perils for Pedestrians

2011-02-28
What do the cities of Bordeaux, France; Amsterdam, Holland; and Portland, Oregon, USA have in common? If you're a bicyclist, you probably know that in these locations, cycling is a popular way of getting around. If you're not a bicyclist, you might just become one after viewing the latest episode of "Perils for Pedestrians", airing Tuesday, March 1, at 7:30 p.m. EST on The Universityhouse Channel. Program host John Z. Wetmore brings viewers to a major transportation event in Brussels, Belgium to show how the bicycle is experiencing a resurgence as a clean, cost-effective, ...

SAFE International Expands Workplace Violence and Harassment Training Courses - Canada Self Defense

2011-02-28
Canada Self Defense, SAFE International Expands Workplace Violence And Harassment Training Courses. SAFE International is the leading provider of mobile self defense/personal protection training in Canada. SAFE International has taught more than 120,000 clients in the private, corporate and high school environments since 1994. SAFE International is expanding its Workplace Violence and Harassment Training Courses throughout Canada and all of North America. The company is owned and managed by Chris Roberts who is a professional teaching Director and self-defense consultant. SAFE ...

Learn Ways to Heat Up Your Romance from Top Relationship Expert

2011-02-28
Even if February 14th crept up on you, you still have time to make this month your best ever! Here are five more ways to make Valentine's Day, and EVERY day, the passionate and romantic! 1. If Wheaties is the breakfast cereal of champions, then champagne is the drink of lovers! Champagne, in moderation, is known to lower one's inhibitions and produces a feeling of warmth throughout the body. If this doesn't set the tone for you, I don't know what will! But if you are not into champagne or any alcohol for that matter, try some nice hot chocolate with marshmallows. There ...

Old Colony Elder Services Announces the "Dancing With the Angels" Event will be held April 2nd - A Benefit for the Special Needs Fund for Frail Elders

2011-02-28
recently announced that the second annual "Dancing with the Angels" benefit event will be held on Saturday, April 2, 2011 from 6:30 to 11 p.m., at the Tirrell Room, 254 Quarry Street in Quincy. The "Dancing with the Angels" event is generously hosted by Visiting Angels of the South Shore located in Marshfield. Attendees will enjoy hors d'oeuvres, lively dancing and the music of the 14 piece White Heat Swing Orchestra. There will also be a dancing competition featuring the Visiting Angels staff doing Latin dancing. This fundraising event supports the Special Needs ...

The Perfect Dog Bed.com Launches a New Site with a Lofty Idea

2011-02-28
ThePerfectDogBed.com opens its virtual doors for business on March 1, 2011. Upon first glance this may seem like a typical sales website with lots of products, brand names, and discounts. But with closer inspection, it is soon discovered that this site stands on something different. This reseller wants to be an informational hub. The site director, Kay S. explains, 'There are so many pet products out there being sold, and not enough information about how to classify and sort through everything. We looked at dog beds in particular and just noticed the dearth of knowledge. ...
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