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Alzheimer's disease may be easily misdiagnosed

2011-02-24
ST. PAUL, Minn. – New research shows that Alzheimer's disease and other dementing illnesses may be easily misdiagnosed in the elderly, according to early results of a study of people in Hawaii who had their brains autopsied after death. The research is being released today and will be presented as part of a plenary session at the American Academy of Neurology's 63rd Annual Meeting in Honolulu April 9 to April 16, 2011. "Diagnosing specific dementias in people who are very old is complex, but with the large increase in dementia cases expected within the next 10 years ...

All about addiction

2011-02-24
Addiction is a brain disease that destroys lives, devastates families and tears at the very fabric of society. Effective prevention and treatment of addiction requires a clear understanding of the complex brain mechanisms that underlie addictive behaviors, and research has provided a fascinating view of how substance abuse hijacks neuronal circuits involved in reward and motivation and causes profound and persistent changes in behavior. Now, a special issue of the journal Neuron, published on February 24th by Cell Press, provides new insight into to the most recent advances ...

Entire T-cell receptor repertoire sequenced revealing extensive and unshared diversity

2011-02-24
February 24, 2011 – T-cell receptor diversity in blood samples from healthy individuals has been extensively cataloged for the first time in a study published online today in Genome Research (www.genome.org), setting the stage for a better understanding of infectious disease, cancer, and immune system disorders. Adaptive immunity is mediated by T-cells, a white blood cell that identifies and attacks cells that may be infected with viruses or contain cancer-causing mutations. To recognize a wide array of potentially infectious agents or cancer-causing mutations, gene ...

Spinal fluid proteins distinguish lyme disease from chronic fatigue syndrome

2011-02-24
Patients who suffer from Neurologic Post Treatment Lyme disease (nPTLS) and those with the Chronic Fatigue Syndrome report similar symptoms. However unique proteins discovered in spinal fluid can distinguish those two groups from one another and also from people in normal health, according to new research conducted by a team led by Steven E. Schutzer, MD, of the University of Medicine and Dentistry of New Jersey – New Jersey Medical School, and Richard D. Smith, Ph.D., of Pacific Northwest National Laboratory. This finding, published in the journal PLoS ONE (February ...

Gaze following abilities in wolves

2011-02-24
Following others' gaze direction is an important source of information that helps to detect prey or predators, to notice important social events within one's social group and to predict the next actions of others. As such, it is considered a key step towards an understanding of mental states, such as attention and intention. Many animals will follow the gaze of others into distant space. Following a gaze around a barrier, which is considered to be a more cognitively advanced task, is much less common. Friederike Range and Zsofi Viranyi at the University of Vienna ...

Scientists create illusion of having 3 arms

2011-02-24
How we experience our own bodies is a classical question in psychology and neuroscience. It has long been believed that our body image is limited by our innate body plan – in other words that we cannot experience having more than one head, two arms and two legs. However, brain scientists at the Swedish medical university Karolinska Institutet have now shown that it is possible to make healthy volunteers experience having three arms at the same time. In a novel paper published in the online scientific journal PLoS ONE they describe how it is possible to create an illusion ...

Lasers ID deadly skin cancer better than doctors

2011-02-24
DURHAM, N.C. – High-resolution images from a laser-based tool developed at Duke University could help doctors better diagnose melanoma, the deadliest form of skin cancer, while potentially saving thousands of lives and millions of dollars in unnecessary healthcare costs each year. The tool probes skin cells using two lasers to pump small amounts of energy, less than that of a laser pointer, into a suspicious mole. Scientists analyze the way the energy redistributes in the skin cells to pinpoint the microscopic locations of different skin pigments. For the first time, ...

Hyperactive nerve cells may contribute to depression

2011-02-24
UPTON, NY - Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, Cold Spring Harbor Laboratory, and the University of California, San Diego School of Medicine, have identified hyperactive cells in a tiny brain structure that may play an important role in depression. The study, conducted in rats and appearing in the February 24, 2011, issue of Nature, is helping to reveal a cellular mechanism for depressive disorders that could lead to new, effective treatments. The research provides evidence that inhibition of this particular brain region ...

Aging, interrupted

Aging, interrupted
2011-02-24
VIDEO: Salk scientist Dr. Belmonte discusses the research. Click here for more information. LA JOLLA, CA—The current pace of population aging is without parallel in human history but surprisingly little is known about the human aging process, because lifespans of eight decades or more make it difficult to study. Now, researchers at the Salk Institute for Biological Studies have replicated premature aging in the lab, allowing them to study aging-related disease in a dish. In ...

New biological pathway identified for post-traumatic stress disorder

2011-02-24
High blood levels of a hormone produced in response to stress are linked to post-traumatic stress disorder in women but not men, a study from researchers at Emory University and the University of Vermont has found. The results are scheduled for publication in the Feb. 24 issue of Nature. The hormone, called PACAP (pituitary adenylate cyclase-activating polypeptide), is known to act throughout the body and the brain, modulating central nervous system activity, metabolism, blood pressure, pain sensitivity and immune function. The identification of PACAP as an indicator ...

New 'thunder-thighs' dinosaur discovered

2011-02-24
LONDON – A new dinosaur named Brontomerus mcintoshi, or "thunder-thighs" after its enormously powerful thigh muscles, has been discovered in Utah, USA. The new species is described in a paper recently published in the journal Acta Palaeontologica Polonica by an international team of scientists from the U.K. and the U.S. A member of the long-necked sauropod group of dinosaurs which includes Diplodocus and Brachiosaurus, Brontomerus may have used its powerful thighs as a weapon to kick predators, or to help travel over rough, hilly terrain. Brontomerus lived about 110 ...

Quantum hot potato: NIST researchers entice 2 atoms to swap smallest energy units

Quantum hot potato: NIST researchers entice 2 atoms to swap smallest energy units
2011-02-24
BOULDER, Colo.—Physicists at the National Institute of Standards and Technology (NIST) have for the first time coaxed two atoms in separate locations to take turns jiggling back and forth while swapping the smallest measurable units of energy. By directly linking the motions of two physically separated atoms, the technique has the potential to simplify information processing in future quantum computers and simulations. Described in a paper published Feb. 23 by Nature,* the NIST experiments enticed two beryllium ions (electrically charged atoms) to take turns ...

Virus-mimicking nanoparticles can stimulate long lasting immunity

2011-02-24
Vaccine scientists say their “Holy Grail” is to stimulate immunity that lasts for a lifetime. Live viral vaccines such as the smallpox or yellow fever vaccines provide immune protection that lasts several decades, but despite their success, scientists have remained in the dark as to how they induce such long lasting immunity. Scientists at the Emory Vaccine Center have designed tiny nanoparticles that resemble viruses in size and immunological composition and that induce lifelong immunity in mice. They designed the particles to mimic the immune‑stimulating effects ...

Quantum computer -- tune in now

Quantum computer -- tune in now
2011-02-24
The Austrian research group led by physicist Rainer Blatt suggests a fundamentally novel architecture for quantum computation. They have experimentally demonstrated quantum antennae, which enable the exchange of quantum information between two separate memory cells located on a computer chip. This offers new opportunities to build practical quantum computers. The researchers have published their work in the scientific journal Nature. Six years ago scientists at the University of Innsbruck realized the first quantum byte – a quantum computer with eight entangled quantum ...

Microbes help children to breathe easily

2011-02-24
The incidence of asthma among children in Europe continues to rise. But not all children are equally at risk. Several studies published over the past few years have shown that children living on farms are significantly less likely to develop asthma than others. An international team of researchers including Dr. Markus Ege and Professor Erika von Mutius of Children's Surgical Clinic in the Dr. von Hauner Children's Hospital (Medical Center of the University of Munich) has just published an epidemiological study that confirms this finding. It shows that the lower susceptibility ...

Quantum simulator becomes accessible to the world

Quantum simulator becomes accessible to the world
2011-02-24
Experimental physicists have put a lot of effort in isolating sensitive measurements from the disruptive influences of the environment. In an international first, Austrian quantum physicists have realized a toolbox of elementary building blocks for an open-system quantum simulator, where a controlled coupling to an environment is used in a beneficial way. This offers novel prospects for studying the behavior of highly complex quantum systems. The researchers have published their work in the scientific journal Nature. Many phenomena in our world are based on the nature ...

Before the explosion -- volcano's warning tremors explained

Before the explosion -- volcanos warning tremors explained
2011-02-24
New Haven, Ct. - No matter their size or shape, explosive volcanoes produce tremors at similar frequencies for minutes, days or weeks before they erupt. In the Feb. 24 issue of the journal Nature, researchers at Yale University and the University of British Columbia (UBC) describe a model that explains this strange phenomenon – and may help forecast deadly eruptions. When such volcanoes erupt they can shoot hot ash up to 40 kilometers into the atmosphere and cause devastating destruction when the ash column collapses and spreads as "pyroclastic flows." Prior to most ...

Researchers use genomics to investigate TB outbreak

2011-02-24
Vancouver, BC - Scientists supported by Genome BC have set a new standard for studying outbreaks of infectious disease by combining advanced genomics with a detailed map of the social relationships between cases to investigate a recent outbreak of tuberculosis in a BC community. The study tracked 41 individuals who developed tuberculosis: patient interviews revealed a tightly-knit community where most patients knew one another, while DNA fingerprinting of the bacterial samples from each individual showed them to be identical to each other. These two factors together ...

Stanford study shows how metaphors shape the debate about crime fighting

2011-02-24
Imagine your city isn't as safe as it used to be. Robberies are on the rise, home invasions are increasing and murder rates have nearly doubled in the past three years. What should city officials do about it? Hire more cops to round up the thugs and lock them away in a growing network of prisons? Or design programs that promise more peace by addressing issues like a faltering economy and underperforming schools? Your answer – and the reasoning behind it – can hinge on the metaphor being used to describe the problem, according to new research by Stanford psychologists. ...

Convenient blood test not as effective for diagnosing diabetes in children

2011-02-24
ANN ARBOR, Mich. – Doctors are increasingly using a convenient blood glucose test for diagnosing diabetes and pre-diabetes, but a study by the University of Michigan's C.S. Mott Children's Hospital shows it's not the best way to diagnose diabetes in children. The hemoglobin A1c test has become the preferred way to diagnose diabetes among the millions of Americans who have diabetes but show no symptoms. The simple test measures longer-term blood sugar levels -- without requiring patients to fast overnight. But U-M researchers say more study is needed before doctors ...

Americans and Canadians get different drug information online: UBC study

2011-02-24
Americans and Canadians are getting vastly different search results when they look up prescription drug information online, says a study by researchers at the University of British Columbia. Residents of the United States searching on Google for both brand and generic drug names get directed to the government-run National Library of Medicine. However, Canadians performing the same searches end up getting Wikipedia for generic drug searches, and drug company sites for brand searches, according to the study, published online yesterday by the Annals of Pharmacotherapy. "The ...

Simpler way of making proteins could lead to new nanomedicine agents

Simpler way of making proteins could lead to new nanomedicine agents
2011-02-24
CHAMPAIGN, Ill. — Researchers have developed a simple method of making short protein chains with spiral structures that can also dissolve in water, two desirable traits not often found together. Such structures could have applications as building blocks for self-assembling nanostructures and as agents for drug and gene delivery. Led by Jianjun Cheng, a professor of materials science and engineering at the University of Illinois, the research team will publish its findings in the Feb. 22 edition of the journal Nature Communications. Materials scientists have been interested ...

Semporna may have richest marine biodiversity in the world

2011-02-24
The preliminary results of the Semporna Marine Ecological Expedition (December 2010) indicate that Semporna may have the world's highest marine biodiversity. The expedition yielded a record number of 43 species of mushroom corals. Furthermore, some new species were discovered, among which at least two shrimps and possibly a number of gall crabs. The health of the reefs was judged to be relatively poor: 36% of the transects had fair, another 36% had poor live coral cover. Eighteen scientists from Malaysia, the Netherlands and the USA spent three weeks examining the reefs ...

Review highlights need for more education and guidance on CAM use in midwifery

2011-02-24
Complementary and alternative medicine (CAM) is increasingly popular in maternity care, but healthcare professionals need formal evidence-based education and guidance about its use, according to a review in the March issue of the Journal of Advanced Nursing. There is also need for greater respect and cooperation between conventional and alternative practitioners and improved communication with patients about the growing use of CAM. University-based members of the Network of Researchers in the Public Health of Complementary and Alternative Medicine (NORPHCAM) reviewed ...

New vaccine technology protects mice from hepatitis C virus

2011-02-24
Immunology: Three percent of the world's population is currently infected by hepatitis C. The virus hides in the liver and can cause cirrhosis and liver cancer, and it's the most frequent cause of liver transplants in Denmark. Since the virus mutates strongly, we have no traditional vaccine, but researchers at the University of Copenhagen are now the first to succeed in developing a vaccine, which provides future hope for medical protection from this type of hepatitis. "The hepatitis C virus (HCV) has the same infection pathways as HIV," says Jan Pravsgaard Christensen, ...
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