PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Kidney disease in Canada: 12.5 percent of adults afflicted, yet many unaware

2013-05-06
(Press-News.org) An estimated 12.5% of Canadians in Canada have evidence of chronic kidney disease, including people without risk factors such as high blood pressure and diabetes, according to a study published in CMAJ.

Chronic kidney disease is a risk factor for death, and it places a significant burden on the health care system; dialysis for 1 person alone over 1 year costs about $60 000.

Estimates of kidney disease in Canada are based on extrapolations of the prevalence of end-stage renal disease. In this study, researchers looked at blood and urine samples from 3689 participants in the Canadian Health Measures Survey aged 18–79 years from across Canada to generate a national estimate of chronic kidney disease. Kidney disease (all stages) was present in 12.5% or 2.9 million Canadian adults during the study period from 2007 to 2009. High blood pressure and diabetes were more common in people with chronic kidney disease than without (25% v.15% for high blood pressure and 11% v. 5.4% for diabetes). However, 72% of adults with chronic kidney disease had neither condition.

Prevalence rates are similar to US rates, although higher than in Europe and Australia.

Awareness of kidney dysfunction was low, with only 5.3% of adults with any stage of chronic kidney disease having been diagnosed and only 12% of people with later stage kidney disease knowing they were ill.

Screening for kidney disease in people with hypertension, diabetes and other chronic diseases is recommended by some associations, but it is not cost effective for the general population, seniors and people with hypertension.

"Because most of these people did not have diabetes or hypertension, conditions most likely to prompt screening for kidney dysfunction, they may be easily missed based on current practices. A comprehensive, evidence-based Canadian guideline for screening adults for chronic kidney disease would be useful to optimize early intervention and secondary prevention of chronic kidney disease and its associated outcomes," the authors conclude. ### END


ELSE PRESS RELEASES FROM THIS DATE:

Single, high-dose erythropoietin given 2 days pre-op reduces need for transfused blood

2013-05-06
Minneapolis, MN, May 6, 2013 – Anemia increases operative mortality and morbidity in non-cardiac and cardiac surgical procedures. Anemic surgical patients may require more blood transfusions, raising the risk of transfusion-related complications and increasing costs. For those reasons, optimizing patient readiness by correcting anemia prior to surgery is an important clinical goal. A simple new protocol has been proposed that helps correcting anemia using a single, high dose of recombinant human erythropoietin (HRE) administered only two days prior to surgery. The results ...

Managing fibromyalgia: A guide for physicians

2013-05-06
Fibromyalgia, now recognized as a true health syndrome with origins in the central nervous system, has seen many recent evolutions regarding its diagnosis and management which should instil new approaches, states a review article published in CMAJ. "The cause of fibromyalgia is unknown, but there is some evidence for a genetic predisposition, abnormalities in the stress response system or hypothalamic–pituitary axis, and possible triggering events," writes Dr. Mary-Ann Fitzcharles, Research Institute of the McGill University Health Centre (RI-MUHC) and McGill University, ...

Minimal dose CT superior to chest X-ray for detection of recurrent lung cancer

2013-05-06
Minneapolis, MN, May 6, 2013 – Lung cancer is associated with very high mortality, in part because it is hard to detect at early stages, but also because it can recur frequently after surgical removal. The question arises as to what is the best way to follow lung cancer patients after surgery in order to spot problems early enough, before symptoms become obvious, so that patients may still be eligible for new interventions. In this study presented at the 93rd AATS Annual Meeting, investigators from the University of Toronto departments of Thoracic Surgery and Diagnostic ...

Low-dose anticoagulation therapy used with new design mechanical heart valve lowers bleeding risk

2013-05-06
Minneapolis, MN, May 6, 2013 – For more than 40 years, patients under 65 years of age requiring heart valve replacement have had to choose between a mechanical valve that offers life-long durability but requires aggressive warfarin anticoagulation or a biological (cow or pig) valve that will wear out in 10-20 years but does not require anticoagulation. Aggressive warfarin anticoagulation is accompanied by significant annual risk of bleeding, while inadequate anticoagulation of a mechanical artificial valve has been associated with high risk of clotting problems that can ...

Activity of cancer inducing genes can be controlled by the cell's skeleton

2013-05-06
Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis. A category of genes, called oncogenes, is critical during cancer progression, as they codify proteins whose activity favours the development of cancer. One of these molecules, Src, is implicated in a large number of human cancers. However, it is still not clear how healthy cells constrain its activity not to become tumorous. In the latest issue of the journal Oncogene*, ...

Progerin's 'discrimination' may contribute to fatal disease HGPS

2013-05-06
A mutant protein responsible for Hutchinson-Gilford Progeria syndrome (HGPS) bars large proteins from entering the nucleus, according to a study in The Journal of Cell Biology. The culprit in HGPS, a fatal disease that resembles premature aging, is a protein variant called Progerin. This defective protein impairs cells in many ways, including reducing nuclear levels of the RanGTPase. Ran is crucial for nuclear import and export, as it stimulates unloading of cargo that has just entered the nucleus and loading of cargo that's ready to exit. Progerin also impedes the import ...

Wip1 could be new target for cancer treatment

2013-05-06
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new target for the treatment of certain cancers. Like a battlefield surgeon who has to decide which casualties can be saved, p53 performs triage on cells with injured DNA. If the damage is serious, p53 spurs the cells to die or stop proliferating. But after milder hits, p53 activates a DNA damage response (DDR) mechanism, which instigates repairs, and temporarily prevent ...

New Canadian guidelines for treating fibromyalgia

2013-05-06
Physicians from the McGill University Health Centre (MUHC) and the University of Calgary have published a review article in the CMAJ (Canadian Medical Association Journal) to help family doctors diagnose and treat fibromyalgia. The article represents the first time researchers have published Canadian guidelines to help manage the condition. Fibromyalgia is a chronic condition that affects the central nervous system causing pain throughout the body. It is often accompanied by fatigue, depression and sleep problems. It affects mostly women and their multiple symptoms ...

Ubiquitous engineered nanomaterials cause lung inflammation, study finds

2013-05-06
(SACRAMENTO, Calif.) -- A consortium of scientists from across the country has found that breathing ultrafine particles from a large family of materials that increasingly are found in a host of household and commercial products, from sunscreens to the ink in copy machines to super-strong but lightweight sporting equipment, can cause lung inflammation and damage. The research on two of the most common types of engineered nanomaterials is published online today in Environmental Health Perspectives, the journal of the National Institute of Environmental Health Sciences (NIEHS). ...

LCSB discovers endogenous antibiotic in the brain

2013-05-06
Luxembourg, 6 May 2013 – Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have discovered that immune cells in the brain can produce a substance that prevents bacterial growth: namely itaconic acid. Until now, biologists had assumed that only certain fungi produced itaconic acid. A team working with Dr. Karsten Hiller, head of the Metabolomics Group at LCSB, and Dr. Alessandro Michelucci has now shown that even so-called microglial cells in mammals are also capable of producing this acid. "This is a ground breaking result," ...

LAST 30 PRESS RELEASES:

Scientists identify smooth regional trends in fruit fly survival strategies

Antipathy toward snakes? Your parents likely talked you into that at an early age

Sylvester Cancer Tip Sheet for Feb. 2026

Online exposure to medical misinformation concentrated among older adults

Telehealth improves access to genetic services for adult survivors of childhood cancers

Outdated mortality benchmarks risk missing early signs of famine and delay recognizing mass starvation

Newly discovered bacterium converts carbon dioxide into chemicals using electricity

Flipping and reversing mini-proteins could improve disease treatment

Scientists reveal major hidden source of atmospheric nitrogen pollution in fragile lake basin

Biochar emerges as a powerful tool for soil carbon neutrality and climate mitigation

Tiny cell messengers show big promise for safer protein and gene delivery

AMS releases statement regarding the decision to rescind EPA’s 2009 Endangerment Finding

Parents’ alcohol and drug use influences their children’s consumption, research shows

Modular assembly of chiral nitrogen-bridged rings achieved by palladium-catalyzed diastereoselective and enantioselective cascade cyclization reactions

Promoting civic engagement

AMS Science Preview: Hurricane slowdown, school snow days

Deforestation in the Amazon raises the surface temperature by 3 °C during the dry season

Model more accurately maps the impact of frost on corn crops

How did humans develop sharp vision? Lab-grown retinas show likely answer

Sour grapes? Taste, experience of sour foods depends on individual consumer

At AAAS, professor Krystal Tsosie argues the future of science must be Indigenous-led

From the lab to the living room: Decoding Parkinson’s patients movements in the real world

Research advances in porous materials, as highlighted in the 2025 Nobel Prize in Chemistry

Sally C. Morton, executive vice president of ASU Knowledge Enterprise, presents a bold and practical framework for moving research from discovery to real-world impact

Biochemical parameters in patients with diabetic nephropathy versus individuals with diabetes alone, non-diabetic nephropathy, and healthy controls

Muscular strength and mortality in women ages 63 to 99

Adolescent and young adult requests for medication abortion through online telemedicine

Researchers want a better whiff of plant-based proteins

Pioneering a new generation of lithium battery cathode materials

A Pitt-Johnstown professor found syntax in the warbling duets of wild parrots

[Press-News.org] Kidney disease in Canada: 12.5 percent of adults afflicted, yet many unaware