(Press-News.org) Rockville, Md. — Vision researchers have developed new software that will analyze visual fields in an open-source platform to improve and encourage collaborative research among independent labs. An analysis of the free tool is presented in a Journal of Vision (JOV) paper, The visualFields package: A tool for analysis and visualization of visual fields.
In the paper, authors introduce and demonstrate the visualFields package, which can work separately or in conjunction with the Open Perimetry Interface — an open-source software developed by Andrew Turpin, PhD, and described in a previous JOV article (The Open Perimetry Interface: An enabling tool for clinical visual psychophysics). The interface allows researchers to operate commercially available instruments called perimeters that are designed to examine the visual field of patients.
"With open-source resources like these, research can be conducted in a completely transparent manner," said author Iván Marín-Franch, PhD, of the University of Valencia (Departamento de Óptica at Universitat de València) and formerly of Indiana University School of Optometry. "And unlike with most proprietary software, results can be verified and methods more closely scrutinized by independent researchers."
The visualFields package contains analytical and visualization tools, including methods for detection and follow-up of glaucoma. To demonstrate the visualFields package, the research team used the right eye of a patient with glaucoma who participated in the Bloomington longitudinal study. Results included four examples of visual field analysis along with the corresponding code used for their generation.
"The necessity for moving from proprietary software into a fully open-source framework has been in the psyche of the glaucoma research community for many years," said Marín-Franch. In looking at the future, he and his colleagues suggest that Open Perimetry Initiative (OPI) would allow groups or individual researchers to test their models with large datasets of real data that they would not have access to otherwise. They also propose centers with good infrastructure would be able conduct clinical trials using state-of-the-art methods for analyzing their data right away and without incurring any cost.
"But, the success of OPI relies strongly on active collaboration from every end of the research community: Some by donating their datasets, some by donating the implementations of their research methods," cautions Marín-Franch.
The researchers make clear that the visualFields package is not intended to replace well-tested, commercially available stand-alone software; rather, it is meant to be an environment for experimentation and research that is free and open for scientists to use and offer ways to improve upon it.
###
ARVO's Journal of Vision (http://www.journalofvision.org) is an online-only, peer-reviewed, open-access publication devoted to visual function in humans and animals. It explores topics such as spatial vision, perception, low vision, color vision and more, spanning the fields of neuroscience, psychology and psychophysics. JOV is known for hands-on datasets and models that users can manipulate online.
The Association for Research in Vision and Ophthalmology (ARVO) is the largest eye and vision research organization in the world. Members include some 12,000 eye and vision researchers from over 70 countries. ARVO encourages and assists research, training, publication and knowledge-sharing in vision and ophthalmology.
Visit us at:
Website: http://www.arvo.org
Twitter: http://www.twitter.com/#!/ARVOinfo
Facebook: http://www.facebook.com/ARVOinfo
Flickr: http://www.flickr.com/photos/ARVOinfo
YouTube: http://www.youtube.com/user/ARVOinfo
END
ARLINGTON HEIGHTS, ILL. -- The allergist's office might not be a child's favorite place to visit, but it is a place where they should be able to say how their asthma makes them feel. While children might rely on parents to tell their doctor about how they are feeling, according to a study released today, children should do most of the talking.
The study, published in the July issue of Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), found that children with asthma report having a better quality ...
This news release is available in German. The economic crisis has put measurable pressure on birthrates in Europe over the last decade. On average, the more the unemployment rose, the greater the decrease in fertility compared to the number of children per women expected without the crisis. This is the result of a new study performed by the Max Planck Institute for Demographic Research (MPIDR) in Rostock, Germany. MPIDR demographers Michaela Kreyenfeld, Joshua Goldstein and Aiva Jasilioniene have just published their analysis together with Deniz Karaman Örsal of the ...
LA JOLLA, CA - Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments or whole chromosomes that were not incorporated into daughter cells after cell division, are associated with specific forms of cancer and are predictive of poorer prognosis.
In a new study, published on July 3 in Cell, a team of scientists at the Salk Institute for Biological Studies finds that disrupted micronuclei, which can trigger massive DNA damage on chromosomes, might play an even more active role in carcinogenesis ...
Relationship problems can keep us awake at night. But new research from UC Berkeley suggests that sleepless nights also can worsen lovers' fights.
UC Berkeley psychologists Amie Gordon and Serena Chen have found that people are much more likely to lash out at their romantic partners over relationship tensions after a bad night's sleep.
"Couples who fight more are less happy and less healthy," said Gordon, a doctoral student in psychology and lead author of the study published online in the journal, Social Psychological and Personality Science.
"Our research helps ...
Global atmospheric change, stagnation of yield increases, uncertain societal acceptance, and government policies are some of the greatest barriers to meeting the growing demand for food, feed and fuel from our major crops, said guest lecturer Stephen Long at the 2013 American Association for the Advancement of Science (AAAS) and World Food Prize Foundation (WFPF) Charles Valentine Riley Memorial Lecture on June 25 in Washington, D.C.
Biotechnology and new sustainable bioenergy crops will be imperative to overcome these challenges, said Long, a Gutgesell Endowed Professor ...
(SACRAMENTO, Calif.) -- The U.S. News & World Report graduate school rankings inspire discussion and marketing, but do they actually reflect quality differences between schools when it comes to medical education in primary care?
Researchers at the UC Davis School of Medicine are believed to be the first to take on that question by analyzing the primary care rankings from 2009 through 2012, reconstructing scores and proposing alternative measurements. Their findings are published online now, ahead of the August 13 print issue of the journal Academic Medicine.
Printed ...
University of Adelaide researchers have developed a new nanomaterial that could help reduce carbon dioxide emissions from coal-fired power stations.
The new nanomaterial, described in the Journal of the American Chemical Society, efficiently separates the greenhouse gas carbon dioxide from nitrogen, the other significant component of the waste gas released by coal-fired power stations. This would allow the carbon dioxide to be separated before being stored, rather than released to the atmosphere.
"A considerable amount of Australia's – and the world's – carbon dioxide ...
UC Davis MIND Institute researchers have identified the specific antibodies that target fetal brain proteins in the blood of a subset of women whose children are diagnosed with autism. The finding is the first to pinpoint a specific risk factor for a significant subset of autism cases, as well as a biomarker for drug development and early diagnosis. The researchers have named autism related to these antibodies "Maternal Autoantibody-Related," or MAR autism.
The study found that the mothers of children with autism were more than 21 times as likely to have the specific ...
Researchers with the UC Davis MIND Institute have found that prenatal exposure to specific combinations of antibodies found only in mothers of children with autism leads to changes in the brain that adversely affect behavior and development.
The researchers said that the highly specific immunoglobulin-G (IgG) autoantibodies cross the placenta during pregnancy to impact fetal brain development, resulting in a form of autism that the researchers now are calling maternal antibody-related (MAR) autism. The researchers said that MAR autism cases could represent as much as ...
Each year in the United States, cats deposit about 1.2 million metric tons of feces into the environment, and that poop is carrying with it what may be a vast and underappreciated public health problem, say scientists July 9 in the journal Trends in Parasitology, a Cell Press publication.
Some of that poop is laden with an infectious parasite known as Toxoplasma gondii, a protozoan that has recently caused toxoplasmosis epidemics in otherwise healthy people, not just in pregnant women or people with immune deficiencies. Additional concerns have been raised by studies ...