PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Developing & delivering interventions for pregnancy to reduce mother & child deaths

2013-09-04
(Press-News.org) A global group of experts has established research priorities addressing care for women prior to pregnancy, in a consensus statement published in PLOS Medicine this week. Sohni Dean and Zulfiqar Bhutta from the Aga Khan University, Karachi, collaborated with colleagues to identify the most important research areas for preconception care that need to be addressed in order to reduce deaths and disability in women and children.

Prevention of maternal and child mortality has featured prominently in the Millennium Development Goals and the subsequent follow-up targets, but to date there has been little focus on how better preparation for pregnancy could impact on these deaths. The aim of preconception care is to improve outcomes for women, mothers and babies by ensuring that a woman enters pregnancy in the best state possible, but little work has been undertaken on interventions that achieve this purpose.

International experts in maternal and child health used a meticulous process to highlight the topics for prioritization in low and middle-income countries, which have the greatest burden of maternal and child deaths. They examined what was already known and then worked through several stages to reach a consensus. The top-scoring research areas were the cost-effective integration of preconception care into wider health-related programs, increasing health promotion and healthcare provision through community health workers, strategies for reducing women's exposure to tobacco smoke, prevention of pregnancies in adolescents, and promoting birth spacing.

An accompanying Perspective from Joel Ray and colleagues at St Michael's Hospital, Toronto, (not involved in the study), welcomes this initiative and acknowledges the enormous amount of work that has gone into identifying the research priorities for this neglected area. They consider which personnel are best placed to deliver the interventions and indicate that improving female education and literacy are important components of the package to reduce maternal and child mortality.

### Guidance & Guidelines:

Funding: The Bill & Melinda Gates Foundation funded the two-day meeting of MNCH experts that lead to the second iteration of this exercise. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: This work was funded by a grant from the Bill & Melinda Gates Foundation, at which FD works as a Senior Program Officer and KCT worked as a Program Officer in the Family Health Division. ZAB is a member of the Editorial Board of PLOS Medicine. All other authors have declared that no competing interests exist.

Citation: Dean S, Rudan I, Althabe F, Webb Girard A, Howson C, et al. (2013) Setting Research Priorities for Preconception Care in Low- and Middle-Income Countries: Aiming to Reduce Maternal and Child Mortality and Morbidity. PLoS Med 10(9): e1001508. doi:10.1371/journal.pmed.1001508

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER:

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001508

Contact:

Sohni Dean
Albert Einstein Medical Center USA
sohni.dean@gmail.com

AND

Zulfiqar Bhutta
Aga Khan University
Pakistan
zulfiqar.bhutta@aku.edu

Perspective Article

Funding: The authors' research programme is funded by the Canadian Institutes of Health Research, which did not play any role in the preparation of this Perspective.

Competing Interests: The authors have declared that no competing interests exist.

Citation: Young CT, Urquia ML, Ray JG (2013) Preconception Care in Low- and Middle-Income Countries: New Opportunities and a New Metric. PLoS Med 10(9): e1001507. doi:10.1371/journal.pmed.1001507

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER:

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001507

Contact:

Joel Ray
University of Toronto
CANADA
RayJ@smh.ca


ELSE PRESS RELEASES FROM THIS DATE:

Efforts to ensure earlier diagnosis of HIV infection across Europe are still needed

2013-09-04
Late diagnosis of HIV infection and entry into care remains a substantial problem across Europe according to a study published in this week's PLOS Medicine. The study, which was an international collaboration led by Amanda Mocroft from University College London, UK, analysed data from the COHERE in EuroCOORD study, an international collaboration including over 84,000 individuals with HIV infections from 35 European countries from January 2000 to January 2011. The researchers analysed data from over 20 observational studies from across Europe that contribute data to the ...

Roll-out of community voluntary male circumcision is linked to reduced HIV infection levels

2013-09-04
Roll-out of voluntary male circumcision services into the community of Orange Farm, South Africa is linked to substantial reductions in HIV infection levels, according to a study published in this week's PLOS Medicine. The study, (ANRS-12126), conducted by Bertran Auvert and colleagues from the University of Versailles (France), also reported that substantial uptake of voluntary male circumcision in one community was not linked to changes in sexual behavior that might affect HIV infection rates. In this study, Bertran Auvert and colleagues estimated HIV infection levels ...

Electromagnets guide heart device implantation, reduce radiation exposure

2013-09-04
Heart failure patients and others who need implanted cardiac devices to help their heart beat regularly may benefit from a new technology to guide their implantation procedure. It uses electromagnets, which work like a GPS tracking system, instead of radiation-based imaging, researchers reported in the American Heart Association journal Circulation: Arrhythmia and Electrophysiology. Electromagnetic tracking technology was used successfully to implant Cardiac Resynchronization Therapy (CRT) devices in heart failure patients, and substantially cut patients' and doctors' ...

Uncontrolled hypertension is common, but untreated, worldwide

2013-09-04
Hamilton, ON (September 3, 2013) - A global study has found that many patients don't know they have hypertension and, even if they do, too few are receiving adequate drug therapy for their hypertension. This is true in high income countries, like Canada, as well as middle and low income countries, say an international team of researchers led by the Population Health Research Institute (PHRI) of McMaster University and Hamilton Health Sciences. The report, which was published today by JAMA, the journal of the American Medical Association, is part of the PURE (Prospective ...

Iranian telegraph operator, first to propose earthquake early warning system

2013-09-04
SAN FRANCISCO -- In 1909, an Iranian telegraph operator living in the remote desert town of Kerman noticed an unusual movement of the magnetic needle of his telegraph instrument. While other telegraph operators during the late 1800s and early 1900s noticed the phenomenon, the Iranian telegraph operator proposed an earthquake early warning system, as detailed in an article published today by the journal Seismological Research Letters (SRL). Nineteenth century telegraph operators in New Zealand, Switzerland, Chile, the Caribbean and elsewhere noted the usefulness of electric ...

Single combination pill provides benefit to patients with or at risk of CVD

2013-09-04
In a randomized trial that included about 2,000 patients with or at high risk of cardiovascular disease (CVD), use of a fixed-dose combination medication for blood pressure, cholesterol, and platelet control compared to usual care resulted in significantly improved medication adherence after 15 months and small improvements in systolic blood pressure and low-density lipoprotein cholesterol, according to a study in the September 4 issue of JAMA. "The long-term use of cardiovascular disease preventive therapy is low among people with established disease. This shortfall ...

Multinational study shows need for substantial improvement in hypertension diagnosis and treatment

2013-09-04
In a study that included more than 140,000 participants from17 countries of varying income levels, researchers found a large gap between both detection and control of hypertension across all countries studied, with just over half of participants with hypertension aware of their diagnosis, and about one-third of those being treated for hypertension successfully controlling their blood pressure, according to a study in the September 4 issue of JAMA. "High blood pressure is the leading cause of cardiovascular disease (CVD) and deaths globally. It is associated with at least ...

Study evaluates prevalence of diabetes among adults in China

2013-09-04
A study based on a nationally representative sample of adults in China in 2010 indicates that nearly 12 percent of Chinese adults had diabetes and the prevalence of prediabetes was about 50 percent, according to a study in the September 4 issue of JAMA. "Noncommunicable chronic diseases have become the leading causes of mortality and disease burden worldwide. It was estimated that 34.5 million deaths globally were due to noncommunicable diseases in 2010, which reflected a significant increase from 1990. Mortality from diabetes doubled during this period and increased ...

Comparison of antibody levels for 4 different immunization schedules for PCVs

2013-09-04
The use of 4 different 13-valent pneumococcal conjugate vaccine immunization schedules in healthy term infants resulted in no statistically significant differences in antibody levels between the infants after the booster dose at 12 months of age for almost all serotypes, according to a study in the September 4 issue of JAMA. "The World Health Organization (WHO) estimated that more than 800,000 children younger than 5 years died from pneumococcal disease in 2000, making it the leading vaccine-preventable cause of death. Since the licensure in 2000 of the first 7-valent ...

Effect of iron supplementation among children living in malaria-endemic area on incidence of malaria

2013-09-04
Children in a malaria-endemic community in Ghana who received a micronutrient powder with iron did not have an increased incidence of malaria, according to a study in the September 4 issue of JAMA. Previous research has suggested that iron supplementation for children with iron deficiency in malaria-endemic areas may increase the risk of malaria. "In sub-Saharan Africa, malaria is a leading cause of childhood morbidity and mortality, and iron deficiency is among the most prevalent preventable nutritional deficiencies. The provision of iron to children with iron deficiency ...

LAST 30 PRESS RELEASES:

Walking, moving more may lower risk of cardiovascular death for women with cancer history

Intracortical neural interfaces: Advancing technologies for freely moving animals

Post-LLM era: New horizons for AI with knowledge, collaboration, and co-evolution

“Sloshing” from celestial collisions solves mystery of how galactic clusters stay hot

Children poisoned by the synthetic opioid, fentanyl, has risen in the U.S. – eight years of national data shows

USC researchers observe mice may have a form of first aid

VUMC to develop AI technology for therapeutic antibody discovery

Unlocking the hidden proteome: The role of coding circular RNA in cancer

Advancing lung cancer treatment: Understanding the differences between LUAD and LUSC

Study reveals widening heart disease disparities in the US

The role of ubiquitination in cancer stem cell regulation

New insights into LSD1: a key regulator in disease pathogenesis

Vanderbilt lung transplant establishes new record

Revolutionizing cancer treatment: targeting EZH2 for a new era of precision medicine

Metasurface technology offers a compact way to generate multiphoton entanglement

Effort seeks to increase cancer-gene testing in primary care

Acoustofluidics-based method facilitates intracellular nanoparticle delivery

Sulfur bacteria team up to break down organic substances in the seabed

Stretching spider silk makes it stronger

Earth's orbital rhythms link timing of giant eruptions and climate change

Ammonia build-up kills liver cells but can be prevented using existing drug

New technical guidelines pave the way for widespread adoption of methane-reducing feed additives in dairy and livestock

Eradivir announces Phase 2 human challenge study of EV25 in healthy adults infected with influenza

New study finds that tooth size in Otaria byronia reflects historical shifts in population abundance

nTIDE March 2025 Jobs Report: Employment rate for people with disabilities holds steady at new plateau, despite February dip

Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure

Fluoride in drinking water is associated with impaired childhood cognition

New composite structure boosts polypropylene’s low-temperature toughness

While most Americans strongly support civics education in schools, partisan divide on DEI policies and free speech on college campuses remains

Revolutionizing surface science: Visualization of local dielectric properties of surfaces

[Press-News.org] Developing & delivering interventions for pregnancy to reduce mother & child deaths