PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

New dementia diagnosis targets will lead to overdiagnosis

In a personal view published today, a general practitioner says that the new targets for diagnosing dementia will lead to more harm than good

2014-04-02
(Press-News.org) The government is putting pressure on commissioners, and in turn general practitioners, to make more diagnoses of dementia, but no analysis has been done to assess the harm that these targets could cause.

Dr Martin Brunet, a GP from Surrey, says that "medicine depends on a fundamental, unspoken agreement between patients and doctors […] the only factor influencing the decision to diagnose should be the best interests of patients". He adds that the idea of doctors being motivated by self interest is "abhorrent and undermines the basis of the relationship".

He says that diagnosis can bring "great harm if incorrect" but the setting of target rates for diagnoses has gone "largely unchallenged despite its potential to lead to substantial harm", adding that clinical commissioning groups will be "desperate" to remove themselves from the list of worst performing CCGs for dementia diagnosis.

Dr Brunet is concerned that there has, so far, been no analysis of the potential harms in setting targets for diagnoses and fears that the "needs of patients are made secondary to the requirement to fulfil quotas".

In a concluding statement, Dr Brunet says that dementia is a "big business" and there are many vested interests that "stand to benefit from a rise in the number of diagnoses". He says that if the validity of these strategies is not questioned, there is the danger of this spreading into other areas of medicines.

He concludes that "diagnosis must always belong only to the patient" and that an "urgent debate is needed before this gets out of hand".

INFORMATION: END


ELSE PRESS RELEASES FROM THIS DATE:

The Sun's campaign may actually harm women

2014-04-02
The "check 'em Tuesday" campaign is a weekly call for women to examine their breasts. Readers are asked to send in photos to prove compliance and can even sign up for a text message reminder. But Dr McCartney argues that teaching women to examine their breasts regularly "has been shown not to reduce deaths from breast cancer and actually increases the chances of a benign biopsy result." She says it is "unfair to tell women that regular self examination will save their lives when it may simply incur anxiety and have the potential to harm." She points out that this is ...

Screening for liver cancer in patients with cirrhosis

2014-04-02
In a systematic review and meta-analysis of 47 studies with 15,158 patients, Amit Singal (University of Texas Southwestern Medical Center) and colleagues found that patients with cirrhosis who underwent surveillance (via liver ultrasound with or without measurement of serum alpha fetoprotein) for hepatocellular carcinoma (HCC) had cancers detected at an earlier stage, were more likely to receive curative instead of palliative treatment, and had longer survival. Across all the studies, the pooled 3-year survival rate was 50.8% among the 4735 patients who underwent HCC surveillance, ...

Heart attack gene, MRP-14, triggers blood clot formation

Heart attack gene, MRP-14, triggers blood clot formation
2014-04-02
Right now, options are limited for preventing heart attacks. However, the day may come when treatments target the heart attack gene, myeloid related protein-14 (MRP-14, also known as S100A9) and defang its ability to produce heart attack-inducing blood clots, a process referred to as thrombosis. Scientists at Case Western Reserve School of Medicine and University Hospitals Case Medical Center have reached a groundbreaking milestone toward this goal. They have studied humans and mice and discovered how MRP-14 generates dangerous clots that could trigger heart attack or ...

Will roe deer persist? Climate change spells disaster for species unable to keep up

2014-04-02
As the climate continues to change, it's unclear to what extent different species will be able to keep pace with altered temperatures and shifted seasons. Living organisms are the survivors of previous environmental changes and might therefore be expected to adapt, but are there limits? According to research to be published in the Open Access journal PLOS Biology on April 1, some species may be much less able to cope with the effects of climate change than previously thought. The study, by Floriane Plard, Jean-Michel Gaillard, Christophe Bonenfant and colleagues, looked ...

Age-related decline in sleep quality might be reversible

2014-04-02
Sleep is essential for human health. But with increasing age, many people experience a decline in sleep quality, which in turn reduces their quality of life. In a new study publishing April 1 in the Open Access journal PLOS Biology, Scientists at the Max Planck Institute (MPI) for Biology of Ageing in Cologne have investigated the mechanisms by which ageing impairs sleep in the fruit fly. Their findings suggest that age-related sleep decline can be prevented and might even be reversible. To uncover basic age-related sleep mechanisms, the Max Planck scientists studied the ...

Enhancers serve to restrict potentially dangerous hypermutation to antibody genes

2014-04-02
How B lymphocytes are able to direct mutations to their antibody genes to produce millions of different antibodies has fascinated biologists for decades. A new study publishing in the Open Access journal PLOS Biology on April 1 by Buerstedde and colleagues shows that this process of programed, spatially targeted genome mutation (aka. somatic hypermutation) is controlled by nearby transcription regulatory sequences called enhancers. Enhancers are usually known to control gene transcription, and these antibody enhancers are now shown to also act in marking the antibody genes ...

Going batty for jumping DNA as a cause of species diversity

2014-04-02
The vesper bats are the largest and best-known common family of bats, with more than 400 species spread across the globe, ranking second among mammals in species diversity. Authors Ray et al., wanted to get at the root cause of this diversity by taking advantage of two vesper bat species whose genomes have recently been sequenced. They speculated that one cause of this diversity might be jumping elements in the genome, called DNA transposons, which are more active and recent in the evolutionary history of this family than any other mammal. Why and how this DNA transposon ...

Likely culprit in spread of colon cancer identified

Likely culprit in spread of colon cancer identified
2014-04-02
New research at Washington University School of Medicine in St. Louis and Vanderbilt University Medical Center in Nashville has implicated a poorly understood protein called PLAC8 in the spread of colon cancer. While elevated PLAC8 levels were known to be associated with colon cancer, the researchers now have shown that the protein plays an active role in shifting normal cells lining the colon into a state that encourages metastasis. The work appears April 1 in the Journal of Clinical Investigation. "We knew levels of this protein are elevated in colon cancer," said ...

Gene therapy improves limb function following spinal cord injury

2014-04-02
Delivering a single injection of a scar-busting gene therapy to the spinal cord of rats following injury promotes the survival of nerve cells and improves hind limb function within weeks, according to a study published April 2 in The Journal of Neuroscience. The findings suggest that, with more confirming research in animals and humans, gene therapy may hold the potential to one day treat people with spinal cord injuries. The spinal cord is the main channel through which information passes between the brain and the rest of the body. Most spinal cord injuries are caused ...

Mode of action of new multiple sclerosis drug discovered

Mode of action of new multiple sclerosis drug discovered
2014-04-02
This news release is available in German. Just a few short weeks ago, dimethyl fumarate was approved in Europe as a basic therapy for multiple sclerosis. Although its efficacy has been established in clinical studies, its underlying mode of action was still unknown, but scientists from Bad Nauheim's Max Planck Institute for Heart and Lung Research and the University of Lübeck have now managed to decode it. They hope that this knowledge will help them develop more effective therapeutic agents. Multiple sclerosis (MS) is a chronic inflammatory disease of the central ...

LAST 30 PRESS RELEASES:

Study unravels another piece of the puzzle in how cancer cells may be targeted by the immune system

Long-sought structure of powerful anticancer natural product solved by integrated approach

World’s oldest lizard wins fossil fight

Simple secret to living a longer life

Same plant, different tactic: Habitat determines response to climate

Drinking plenty of water may actually be good for you

Men at high risk of cardiovascular disease face brain health decline 10 years earlier than women

Irregular sleep-wake cycle linked to heightened risk of major cardiovascular events

Depression can cause period pain, new study suggests

Wistar Institute scientists identify important factor in neural development

New imaging platform developed by Rice researchers revolutionizes 3D visualization of cellular structures

To catch financial rats, a better mousetrap

Mapping the world's climate danger zones

Emory heart team implants new blood-pumping device for first time in U.S.

Congenital heart defects caused by problems with placenta

Schlechter named Cancer Moonshot Scholar

Two-way water transfers can ensure reliability, save money for urban and agricultural users during drought in Western U.S., new study shows

New issue of advances in dental research explores the role of women in dental, clinical, and translational research

Team unlocks new insights on pulsar signals

Great apes visually track subject-object relationships like humans do

Recovery of testing for heart disease risk factors post-COVID remains patchy

Final data and undiscovered images from NASA’s NEOWISE

Nucleoporin93: A silent protector in vascular health

Can we avert the looming food crisis of climate change?

Alcohol use and antiobesity medication treatment

Study reveals cause of common cancer immunotherapy side effect

New era in amphibian biology

Harbor service, VAST Data provide boost for NCSA systems

New prognostic model enhances survival prediction in liver failure

China focuses on improving air quality via the coordinated control of fine particles and ozone

[Press-News.org] New dementia diagnosis targets will lead to overdiagnosis
In a personal view published today, a general practitioner says that the new targets for diagnosing dementia will lead to more harm than good