PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Scientists identify part of brain linked to gambling addiction

2014-04-07
(Press-News.org) New research reveals that brain damage affecting the insula – an area with a key role in emotions – disrupts errors of thinking linked to gambling addiction. The research, led by Dr Luke Clark from the University of Cambridge, was published today, 07 April, in the journal PNAS.

During gambling games, people often misperceive their chances of winning due to a number of errors of thinking called cognitive distortions. For example, 'near-misses' seem to encourage further play, even though they are no different from any other loss. In a random sequence like tossing a coin, a run of one event (heads) makes people think the other outcome (tails) is due next; this is known as the 'gambler's fallacy'.

There is increasing evidence that problem gamblers are particularly prone to these erroneous beliefs. In this study, the researchers examined the neurological basis of these beliefs in patients with injuries to different parts of the brain.

"While neuroimaging studies can tell us a great deal about the brain's response to complex events, it's only by studying patients with brain injury that we can see if a brain region is actually needed to perform a given task," said Dr Clark.

For the study, the researchers gave patients with injuries to specific parts of the brain (the ventromedial prefrontal cortex, the amygdala, or the insula) two different gambling tasks: a slot machine game that delivered wins and 'near-misses' (like a cherry one position from the jackpot line), and a roulette game involving red or black predictions, to elicit the gambler's fallacy. For the control groups, they also had patients with injuries to other parts of the brain as well as healthy participants undergo the gambling tasks.

All of the groups with the exception of the patients with insula damage reported a heightened motivation to play following near-misses in the slot machine game, and also fell prey to the gambler's fallacy in the roulette game.

Clark added: "Based on these results, we believe that the insula could be hyperactive in problem gamblers, making them more susceptible to these errors of thinking. Future treatments for gambling addiction could seek to reduce this hyperactivity, either by drugs or by psychological techniques like mindfulness therapies."

Gambling is a widespread activity: 73% of people in the UK report some gambling involvement in the past year* and around 50% play games other than the National Lottery. For a small proportion of players (around 1-5%), their gambling becomes excessive, resulting in features seen in addiction. Problem gambling is associated with both debt and family difficulties as well as other mental health problems like depression.

INFORMATION: END


ELSE PRESS RELEASES FROM THIS DATE:

New light shed on key bacterial immune system

2014-04-07
New insights into a surprisingly flexible immune system present in bacteria for combating viruses and other foreign DNA invaders have been revealed by researchers from New Zealand's University of Otago and the Netherlands. A team led by Dr Peter Fineran of the Department of Microbiology and Immunology are studying the genetic basis of adaptive immunity in bacteria that cause potato 'soft rot' and in E. coli bacteria. Through their recent collaboration they have found that these bacterial immune systems are much more robust and responsive than previously thought. Their ...

Genes increase the stress of social disadvantage for some children

2014-04-07
Genes amplify the stress of harsh environments for some children, and magnify the advantage of supportive environments for other children, according to a study that's one of the first to document how genes interacting with social environments affect biomarkers of stress. "Our findings suggest that an individual's genetic architecture moderates the magnitude of the response to external stimuli—but it is the environment that determines the direction" says Colter Mitchell, lead author of the paper and a researcher at the University of Michigan Institute for Social Research ...

Targeting sperm protection in mosquitoes could help combat malaria

2014-04-07
Researchers have discovered a way of reducing the fertility of malaria-carrying mosquitoes, potentially providing a new tactic to combat the disease. Anopheles gambiae mosquitoes are the main transmitters of malaria, which affects around 200 million people every year. The females mate only once during their lives. They store the sperm from this single mating in an organ called the spermatheca, from which they repeatedly take sperm over the course of their lifetime to fertilise the eggs that they lay.. The female needs the sperm to stay healthy whilst they are in storage ...

Solution to platelet 'puzzle' uncovers blood disorder link

Solution to platelet puzzle uncovers blood disorder link
2014-04-07
Melbourne researchers have solved a puzzle as to how an essential blood-making hormone stimulates production of the blood clotting cells known as platelets. Platelets are essential for stopping bleeding and are produced by small fragments breaking off their 'parent' cells, called megakaryocytes. The discovery, made by scientists at the Walter and Eliza Hall Institute, identified how bone marrow cells could become overstimulated and produce too many platelets. In blood diseases such as essential thrombocythemia, too many platelets can lead to clogging of the blood vessels, ...

Seeing double: New study explains evolution of duplicate genes

Seeing double: New study explains evolution of duplicate genes
2014-04-07
From time to time, living cells will accidently make an extra copy of a gene during the normal replication process. Throughout the history of life, evolution has molded some of these seemingly superfluous genes into a source of genetic novelty, adaptation and diversity. A new study shows one way that some duplicate genes could have long-ago escaped elimination from the genome, leading to the genetic innovation seen in modern life. Researchers have shown that a process called DNA methylation can shield duplicate genes from being removed from the genome during natural selection. ...

Antibiotic resistance enzyme caught in the act

2014-04-07
Resistance to an entire class of antibiotics – aminoglycosides -- has the potential to spread to many types of bacteria, according to new biochemistry research. A mobile gene called NpmA was discovered in E. coli bacteria isolated from a Japanese patient several years ago. Global spread of NpmA and related antibiotic resistance enzymes could disable an entire class of tools doctors use to fight serious or life-threatening infections. Using X-ray crystallography, researchers at Emory University School of Medicine made an atomic-scale snapshot of how the enzyme encoded ...

A middle road for Medicaid expansion?

2014-04-07
ANN ARBOR, Mich. — With the political divide over health care reform still strong going into this year's elections, a new analysis of state-level decisions shows signs of an emerging middle way toward reducing the ranks of the uninsured. The approach centers on efforts by governors and legislatures to get federal permission to customize Medicaid expansion in ways that satisfy political conservatives – while still allowing them to collect federal funding to increase health insurance coverage in their state. In a new Viewpoint published online by the Journal of the American ...

Researchers: Permafrost thawing could accelerate global warming

2014-04-07
TALLAHASSEE, Fla. — A team of researchers lead by Florida State University have found new evidence that permafrost thawing is releasing large quantities of greenhouse gases into the atmosphere via plants, which could accelerate warming trends. The research is featured in the newest edition of the Proceedings of the National Academy of Sciences. "We've known for a while now that permafrost is thawing," said Suzanne Hodgkins, the lead author on the paper and a doctoral student in chemical oceanography at Florida State. "But what we've found is that the associated changes ...

New research suggests connection between white matter and cognitive health

2014-04-07
LEXINGTON, Ky. (April 7, 2014) -- A multidisciplinary group of scientists from the Sanders-Brown Center on Aging at the University of Kentucky have identified an interesting connection between the health of the brain tissue that supports cognitive functioning and the presence of dementia in adults with Down syndrome. Published in the Neurobiology of Aging, the study, which focused on detecting changes in the white matter connections of the brain, offers tantalizing potential for the identification of biomarkers connected to the development of dementia, including Alzheimer's ...

Well-known cancer gene NRAS produces 5 variants, study finds

2014-04-07
COLUMBUS, Ohio – A new study shows that a gene discovered 30 years ago and now known to play a fundamental role in cancer development produces five different gene variants (called isoforms), rather than just the one original form, as thought. The study of the NRAS gene by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) identified four previously unknown variants that the NRAS gene produces. The finding might help improve drugs for cancers in which aberrant ...

LAST 30 PRESS RELEASES:

Obesity-associated cancers tripled nationwide over past two decades

Consuming certain sweeteners may increase risk of early puberty

Experts suggest screening women with diabetes for intent to conceive at every doctor visit

Osteoporosis treatment benefits people older than 80

Consuming more protein may protect patients taking anti-obesity drug from muscle loss

Thyroid treatment may improve gut health in people with hypothyroidism

Combination of obesity medication tirzepatide and menopause hormone therapy fuels weight loss

High blood sugar may have a negative impact on men’s sexual health

Emotional health of parents tied to well-being of children with growth hormone deficiency

Oxytocin may reduce mood changes in women with disrupted sleep

Mouse study finds tirzepatide slowed obesity-associated breast cancer growth

CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury

Melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1

Single-cell RNA sequencing reveals Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131–TNF signaling pathway-mediated differentiation of immunosuppressive dendritic ce

Acta Pharmaceutica Sinica B Volume 15, Issue 7 Publishes

New research expands laser technology

Targeted radiation offers promise in patients with metastasized small cell lung cancer to the brain

A high clinically translatable strategy to anti-aging using hyaluronic acid and silk fibroin co-crosslinked hydrogels as dermal regenerative fillers

Mount Sinai researchers uncover differences in how males and females change their mind when reflecting on past mistakes

CTE and normal aging are difficult to distinguish, new study finds

Molecular arms race: How the genome defends itself against internal enemies

Tiny chip speeds up antibody mapping for faster vaccine design

KTU experts reveal why cultural heritage is important for community unity

More misfolded proteins than previously known may contribute to Alzheimer’s and dementia

“Too much going on”: Autistic adults overwhelmed by non-verbal social cues

What’s driving America’s deep freezes in a warming world?

A key role of brain protein in learning and memory is deciphered by scientists

Heart attacks don’t follow a Hollywood script

Erin M. Schuman wins 2026 Nakasone Award for discovery on neural synapse function and change during formation of memories

Global ocean analysis could replace costly in-situ sound speed profiles in seafloor positioning, study finds

[Press-News.org] Scientists identify part of brain linked to gambling addiction