INFORMATION:
Packard P.A., Rodríguez-Fornells A., Stein L.M., Nicolás B., Fuentemilla L.. Tracking explicit and implicit long-lasting traces of fearful memories in humans. Neurobiol Learn Mem. 2014 Sep 26;116C:96-104.
Our brain dissociates emotional response from explicit memory in fearful situations
The study may explain why in some anxiety disorders or post-traumatic stress disorder the patient is unable to get to the root of the problem
2014-11-05
(Press-News.org) Researchers at the Cognition and Brain Plasticity group of the Bellvitge Biomedical Research Institute (IDIBELL) and the University of Barcelona have been tracking the traces of implicit and explicit memories of fear in human. The study has been published in the journal Neurobiology of Learning and Memory and describes how in a context of fear, our brain differently encodes contextual memory of a negative event (the place, what we saw...) and emotional response associated.
The study measures electrodermal activity of 86 individuals in a fearful generated in the laboratory and in a neutral context in which they have to learn a list of words. One week and two weeks after the experiment they are tested to see which words they remembered.
"In both contexts" explains Pau Packard, author of the study, "forgetting curve was normal. Over time they forgot all the words, the explicit trace. Moreover in the fearful context the electrodermal activity, the emotional implicit response, was exactly the same, much higher than in the neutral context. "
"In the traumatic events seems that over time there is a portion of memory that is erased or we do not have access, we forget the details but still maintaining the emotional reaction. The imprint is divided into two separate paths. The brain dissociates the explicit memory of a negative event from the emotional response"
This may help to understand why in pathological situations of post-traumatic stress disorders, the uncontrolled emotional response linked to the negative event is generated without knowing what causes it.
As explained by Lluís Fuentemilla, project coordinator, the study "helps explain how the processing of fearful memories can lead to post-traumatic stress disorder and also opens the door to the investigation of new therapeutic strategies for these disorders because the implicit memory trace in a fearful context does not loose over time and can be detected through electrodermal measures. "
ELSE PRESS RELEASES FROM THIS DATE:
IBS is managed effectively with the right drugs, for the right symptoms
2014-11-05
Bethesda, MD (Nov. 5, 2014) — Up to 15 percent of the general adult population is affected by irritable bowel syndrome (IBS), and most patients struggle to find effective drug therapy. A new guideline from the American Gastroenterological Association (AGA) provides these patients and their physician's guidance. The new guideline and accompanying technical review have been published in Gastroenterology, the official journal of the AGA Institute.
"Because no IBS therapy is uniformly effective, many patients describe a history of a variety of treatments alone or in ...
Understanding of global freshwater fish and fishing too shallow, scientists say
2014-11-05
What sounds counter-intuitive to an activity commonly perceived as quiet is the broad recommendation of scientists at Michigan State University (MSU) recommending that small-scale fishing in the world's freshwater bodies must have a higher profile to best protect global food security.
In this month's journal Global Food Security, scientists note that competition for freshwater is ratcheting up all over the world for municipal use, hydropower, industry, commercial development, and irrigation. Rivers are being dammed and rerouted, lakes and wetlands are being drained, fish ...
CNIO researchers create a mouse model that reproduces noonan syndrome
2014-11-05
Noonan syndrome is a rare disease that is characterised by a set of pathologies, including heart, facial and skeletal alterations, pulmonary stenosis, short stature, and a greater incidence of haematological problems (mainly juvenile myeloid leukaemia, or childhood leukaemia). There is an estimated incidence of 1 case for every 1,000–2,500 births, and calculations show some 20,000–40,000 people suffer from the disease in Spain. From a genetic point of view, this syndrome is associated to mutations in 11 different genes —the K-Ras gene among them— ...
Trial results reveal first targeted treatment to boost survival for esophageal cancer
2014-11-05
PATIENTS with a specific type of oesophageal cancer survived longer when they were given the latest lung cancer drug, according to trial results being presented at the National Cancer Research Institute (NCRI) Cancer Conference today (Wednesday).
Up to one in six patients with oesophageal cancer were found to have EGFR duplication in their tumour cells and taking the drug gefitinib, which targets this fault, boosted their survival by up to six months, and sometimes beyond.
This is the first treatment for advanced oesophageal cancer shown to improve survival in patients ...
Researchers engineer a 'smart bomb' to attack childhood leukemia
2014-11-05
Fatih Uckun, Jianjun Cheng and their colleagues have taken the first steps towards developing a so-called "smart bomb" to attack the most common and deadly form of childhood cancer — called B-lineage acute lymphoblastic leukemia (ALL).
In a November study in the new peer-reviewed, open-access journal EBioMedicine, they describe how this approach could eventually prove lifesaving for children who have relapsed after initial chemotherapy and face a less than 20 percent chance of long-term survival.
"We knew that we could kill chemotherapy-resistant leukemia cells ...
How important is long-distance travel in the spread of epidemics?
2014-11-05
The current Ebola outbreak shows how quickly diseases can spread with global jet travel.
Yet, knowing how to predict the spread of these epidemics is still uncertain, because the complicated models used are not fully understood, says a University of California, Berkeley biophysicist.
Using a very simple model of disease spread, Oskar Hallatschek, assistant professor of physics, proved that one common assumption is actually wrong. Most models have taken for granted that if disease vectors, such as humans, have any chance of "jumping" outside the initial outbreak area ...
Study shows benefits of being fat (but not too fat) for deep-diving elephant seals
2014-11-05
Researchers using a new type of tracking device on female elephant seals have discovered that adding body fat helps the seals dive more efficiently by changing their buoyancy.
The study, published November 5 in the Proceedings of the Royal Society B, looked at the swimming efficiency of elephant seals during their feeding dives and how that changed in the course of months-long migrations at sea as the seals put on more fat. The results showed that when elephant seals are neutrally buoyant--meaning they don't float up or sink down in the water--they spend less energy ...
Oregon research team scores with 'The Concussion Playbook'
2014-11-05
A University of Oregon researcher wants those "R" words to resonate among young athletes. They are key terms used in an online educational tool designed to teach coaches, educators, teens and parents about concussions.
Brain 101: The Concussion Playbook successfully increased knowledge and attitudes related to brain injuries among students and parents in a study that compared its use in 12 high schools with the usual care practices of 13 other high schools during the fall 2011 sports season. The findings are online ahead of print in the Journal of Adolescent Health.
Participants, ...
Blocking mitochondrial fission: An effective treatment for Parkinson's disease?
2014-11-05
A study led by a researcher from Plymouth University in the UK, has discovered that the inhibition of a particular mitochondrial fission protein could hold the key to potential treatment for Parkinson's Disease (PD).
The findings of the research are published today, 5th November 2014, in Nature Communications.
PD is a progressive neurological condition that affects movement. At present there is no cure and little understanding of why some people get the condition. In the UK one on 500 people, around 127,000, have PD.
The debilitating movement symptoms of the disease ...
Cost and effect: Cheaper remedies should rule for diabetes nerve pain, U-M experts say
2014-11-05
ANN ARBOR, Mich. — Millions of people with diabetes take medicine to ease the shooting, burning nerve pain that their disease can cause. And new research suggests that no matter which medicine their doctor prescribes, they'll get relief.
But some of those medicines cost nearly 10 times as much as others, apparently with no major differences in how well they ease pain, say a pair of University of Michigan Medical School experts in a new commentary in the Annals of Internal Medicine.
That makes cost -- not effect -- a crucial factor in deciding which medicine ...
LAST 30 PRESS RELEASES:
Lamprey-inspired amphibious suction disc with hybrid adhesion mechanism
A domain generalization method for EEG based on domain-invariant feature and data augmentation
Bionic wearable ECG with multimodal large language models: coherent temporal modeling for early ischemia warning and reperfusion risk stratification
JMIR Publications partners with the University of Turku for unlimited OA publishing
Strange cosmic burst from colliding galaxies shines light on heavy elements
Press program now available for the world's largest physics meeting
New release: Wiley’s Mass Spectra of Designer Drugs 2026 expands coverage of emerging novel psychoactive substances
Exposure to life-limiting heat has soared around the planet
New AI agent could transform how scientists study weather and climate
New study sheds light on protein landscape crucial for plant life
New study finds deep ocean microbes already prepared to tackle climate change
ARLIS partners with industry leaders to improve safety of quantum computers
Modernization can increase differences between cultures
Cannabis intoxication disrupts many types of memory
Heat does not reduce prosociality
Advancing brain–computer interfaces for rehabilitation and assistive technologies
Detecting Alzheimer's with DNA aptamers—new tool for an easy blood test
Chinese Neurosurgical Journal study develops radiomics model to predict secondary decompressive craniectomy
New molecular switch that boosts tooth regeneration discovered
Jeonbuk National University researchers track mineral growth on bioorganic coatings in real time at nanoscale
Convergence in the Canopy: Why the Gracixalus weii treefrog sounds like a songbird
Subway systems are uncomfortably hot — and worsening
Granular activated carbon-sorbed PFAS can be used to extract lithium from brine
How AI is integrated into clinical workflow lowers medical liability perception
New biotech company to accelerate treatments for heart disease
One gene makes the difference: research team achieves breakthrough in breeding winter-hardy faba beans
Predicting brain health with a smartwatch
How boron helps to produce key proteins for new cancer therapies
Writing the catalog of plasma membrane repair proteins
A comprehensive review charts how psychiatry could finally diagnose what it actually treats
[Press-News.org] Our brain dissociates emotional response from explicit memory in fearful situationsThe study may explain why in some anxiety disorders or post-traumatic stress disorder the patient is unable to get to the root of the problem






