PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

UW researchers develop tool to equitably distribute limited vaccines

2021-01-15
(Press-News.org) MADISON, Wis. -- The demand for COVID-19 vaccines continues to outpace supply, forcing public health officials to decide who should be first in line for a shot, even among those in the same pool of eligible vaccine recipients.

To assist these efforts, researchers at the University of Wisconsin School of Medicine and Public Health and UW Health have developed a tool that incorporates a person's age and socioeconomic status to prioritize vaccine distribution among people who otherwise share similar risks due to their jobs. The tool helps identify those who are at greater risk of severe complications or death from COVID-19.

UW Health has implemented the prioritization algorithm to equitably provide limited doses to frontline health care workers. Other organizations can also access the freely available tool to guide their own vaccine distribution plans.

While the UW-Madison tool was designed with the first phase of eligible recipients in mind, it could be used as vaccine distribution expands to larger populations. As the eligible population increases, the gap between initial supply and demand could grow, making such prioritization tools even more helpful.

"Knowing we're going to have limited vaccine for some time, we wanted to develop an algorithm to equitably distribute vaccinations within these risk groups," says Grace Flood, the director of clinical analytics and reporting in the Office of Population Health at UW Health, who helped lead development of the tool along with the Health Innovation Program within SMPH.

In addition to age, the algorithm uses the Social Vulnerability Index to measure a person's susceptibility to severe COVID-19 based on where they live. The Centers for Disease Control and Prevention developed the SVI metric to help emergency responders identify which neighborhoods and towns will require the most support following natural disasters or public health emergencies.

The SVI incorporates 15 measures in four categories: socioeconomic status, housing composition and disability, minority status and language, and housing and transportation. Race and ethnicity have been closely correlated with higher COVID-19-related hospitalizations and mortality.

Flood and her team incorporated the SVI in accordance with a report by the National Academies of Sciences, Engineering and Medicine that recommended using the index to fairly distribute vaccines. Because Wisconsin publishes data about COVID-19 deaths at the census-tract level, "we were able to determine the relationship for risk of mortality between age and SVI," says Flood. This relationship allowed the researchers to verify that age and SVI combined provide an accurate estimate of an individual's risk.

Since age and SVI are readily available pieces of information about an individual and each contributes to COVID-19 risk, an algorithm that incorporates both elements may serve as one of the best ways to distribute vaccines until supply catches up to demand, says Flood.

The researchers have published their algorithm in the Annals of Family Medicine COVID-19 collection and made it available for download on the project's website.

INFORMATION:

--Eric Hamilton,
(608) 263-1986,
eshamilton@wisc.edu



ELSE PRESS RELEASES FROM THIS DATE:

NIH scientists identify nutrient that helps prevent bacterial infection

NIH scientists identify nutrient that helps prevent bacterial infection
2021-01-15
WHAT: Scientists studying the body's natural defenses against bacterial infection have identified a nutrient--taurine--that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae (Kpn). The finding, published in the journal Cell by scientists from five institutes of the National Institutes of Health, could aid efforts seeking alternatives to antibiotics. Scientists know that microbiota--the trillions of beneficial microbes living harmoniously inside our gut--can protect people from bacterial infections, but little is known about how they provide protection. Scientists are studying the microbiota with an eye to finding or enhancing natural treatments to replace antibiotics, which ...

Study: X-Rays surrounding 'Magnificent 7' may be traces of sought-after particle

Study: X-Rays surrounding Magnificent 7 may be traces of sought-after particle
2021-01-15
A new study, led by a theoretical physicist at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab), suggests that never-before-observed particles called axions may be the source of unexplained, high-energy X-ray emissions surrounding a group of neutron stars. First theorized in the 1970s as part of a solution to a fundamental particle physics problem, axions are expected to be produced at the core of stars, and to convert into particles of light, called photons, in the presence of a magnetic field. Axions may also make up dark matter - the mysterious stuff that accounts for an estimated 85 percent of the total mass of the universe, yet we have so far only seen its gravitational effects on ordinary matter. Even if the X-ray excess turns out not to be ...

Simulating evolution to understand a hidden switch

Simulating evolution to understand a hidden switch
2021-01-15
Computer simulations of cells evolving over tens of thousands of generations reveal why some organisms retain a disused switch mechanism that turns on under severe stress, changing some of their characteristics. Maintaining this "hidden" switch is one means for organisms to maintain a high degree of gene expression stability under normal conditions. Tomato hornworm larvae are green in warmer regions, making camouflage easier, but black in cooler temperatures so that they can absorb more sunlight. This phenomenon, found in some organisms, is called phenotypic switching. Normally hidden, this switching is activated in response to dangerous genetic or environmental changes. Scientists have typically studied this ...

Scientists' discovery is paving the way for novel ultrafast quantum computers

Scientists discovery is paving the way for novel ultrafast quantum computers
2021-01-15
Scientists at the Institute of Physics of the University of Tartu have found a way to develop optical quantum computers of a new type. Central to the discovery are rare earth ions that have certain characteristics and can act as quantum bits. These would give quantum computers ultrafast computation speed and better reliability compared to earlier solutions. The University of Tartu researchers Vladimir Hizhnyakov, Vadim Boltrushko, Helle Kaasik and Yurii Orlovskii published the results of their research in the scientific journal Optics Communications. While in ordinary computers, the units of information are binary digits or bits, in quantum computers the units are quantum bits or qubits. In an ordinary computer, information is mostly ...

Stuck in a rut: Ocean acidification locks algal communities in a simplified state

Stuck in a rut: Ocean acidification locks algal communities in a simplified state
2021-01-15
Tsukuba, Japan - Out with the old, in with the new, as the New Year's saying goes, but not where the marine environment is concerned. Researchers from Japan have discovered that ocean acidification keeps algal communities locked in a simplified state of low biodiversity. In a study published on 11th January 2021 in Global Change Biology, researchers from the University of Tsukuba have revealed that as oceanic carbon dioxide levels rise, the biodiversity and ecological complexity of marine algal communities decline. Ocean acidification is the continuing increase in the acidity of the Earth's oceans, caused by the absorption of atmospheric carbon dioxide (CO2). ...

Revisiting the Global Workspace orchestrating the hierarchical organisation of the human brain

2021-01-15
The celebrations in the 250th anniversary of the birth of Ludwig van Beethoven would not be the same without Herbert von Karajan's brilliant performances conducting Beethoven's memorable symphonies. The execution of any musical symphony is a hugely difficult task, demanding very significant skills on the part of each individual musician - but perhaps the most difficult task lies with the conductor who has to orchestrate the musicians into making the music cohesively come alive and speak to our deepest emotions. In many ways the human brain is like an orchestra, where different regions perform very different types of processing, such ...

Increased risk of Parkinson's disease in patients with schizophrenia

2021-01-15
A new study conducted at the University of Turku, Finland, shows that patients with a schizophrenia spectrum disorder have an increased risk of Parkinson's disease later in life. The increased risk may be due to alterations in the brain's dopamine system caused by dopamine receptor antagonists or neurobiological effects of schizophrenia. The record-based case-control study was carried out at the University of Turku in collaboration with the University of Eastern Finland. The study examined the occurrences of previously diagnosed psychotic disorders and schizophrenia in over 25,000 Finnish Parkinson's disease (PD) patients ...

Spreading the sound

2021-01-15
Tsukuba, Japan - A team of researchers lead by the University of Tsukuba have created a new theoretical model to understand the spread of vibrations through disordered materials, such as glass. They found that as the degree of disorder increased, sound waves traveled less and less like ballistic particles, and instead began diffusing incoherently. This work may lead to new heat- and shatter-resistant glass for smartphones and tablets. Understanding the possible vibrational modes in a material is important for controlling its optical, thermal, and mechanical properties. The propagation of vibrations in the form of sound of a single ...

Scientists synthetize new material for high-performance supercapacitors

2021-01-15
Scientists of Tomsk Polytechnic University jointly with colleagues from the University of Lille (Lille, France) synthetized a new material based on reduced graphene oxide (rGO) for supercapacitors, energy storage devices. The rGO modification method with the use of organic molecules, derivatives of hypervalent iodine, allowed obtaining a material that stores 1.7 times more electrical energy. The research findings are published in Electrochimica Acta academic journal (IF: 6,215; Q1). Photo: modified rGO supercapacitor electrodes A supercapacitor is an electrochemical device for storage and release ...

IOF and IFCC review calls for harmonization of assays for reference bone turnover markers

2021-01-15
Bone turnover markers (BTMs) in blood and urine are useful tools in monitoring osteoporosis treatment effects and may be useful for improving patient adherence. In 2011, a Joint Committee on Bone Metabolism of the International Osteoporosis Foundation (IOF) and the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) designated Procollagen type I N-propeptide (PINP) and the C-terminal telopeptide of type I collagen (β-CTX) in blood as reference bone turnover markers for bone formation and bone resorption, respectively, in osteoporosis. However, the effective clinical implementation of ...

LAST 30 PRESS RELEASES:

OET inaugural cover | 30 years of nanoimprint lithography: Leading the new era of nanomanufacturing

Metalens evolution: From individual devices to integrated arrays

Advancing disaster response with the EBD dataset

Putting solar panels in space could aid Europe’s net-zero transition

Ambient documentation technologies reduce physician burnout and restore ‘joy’ in medicine

Solar panels in space could cut Europe’s renewable energy needs by 80%

Computational approach meets biology to connect neural progenitor cells with human disorders

GLP-1 receptor agonists and cancer risk in adults with obesity

Impact of a weight loss intervention on 1-year weight change in women with stage II/III breast cancer

Novel tool helps identify key targets to strengthen CAR NK cell therapies

New RP-HPLC method for orlistat analysis validated

How AI will transform mental health support for patients with breast cancer

First observations by the Total Anthropogenic and Natural emissions mapping SpectrOmeter-3 (TANSO-3) onboard the Global Observing SATellite for Greenhouse gases and Water cycle “IBUKI GW” (GOSAT-GW)

Optimizing how cells self-organize

Impact of cancer on forensic DNA methylation age estimation

Researchers use photonic origami to fold glass into microscopic 3D optical devices

Dr. Matthew Greenblatt awarded Paul-Gallin Trailblazer Prize for bone stem cell discoveries

Natural products used as disinfectants in prosthodontics and oral implantology

A multisensor approach to accurate snow water equivalent retrieval from space

Researchers find ways to improve liquid hydrogen tank efficiency

New era in transthyretin amyloidosis: From stabilizers to gene editing

Cumulative hepatitis B surface antigen/hepatitis B virus DNA ratio in immune-tolerant hepatitis B patients

Increased patient-provider communication, education about COPD needed to improve patient care

Nation’s leading breast health advocate receives Benjamin Spock Award for Compassion in Medicine

Chung-Ang University researchers demonstrate paper electrode-based crawling soft robots

New tracer could enable surgeons to see and hear prostate cancer

One catalyst, two reactions: Toward more efficient chemical synthesis

Regenerative agriculture highlighted as a transformative approach to ecological farming and soil recovery

SLAS Technology unveils AI-powered diagnostics & future lab tech

Hospital stays among migrants in Austria much lower than among Austrians

[Press-News.org] UW researchers develop tool to equitably distribute limited vaccines