Trauma admissions during COVID-19 pandemic in LA county

Scientists at the University of Groningen (The Netherlands), in collaboration with colleagues from the University of Torino (Italy), have developed a method to visualize and quantify alternative structures of RNA molecules. These alternative RNA 'shapes' can have important functional relevance in viruses and bacteria. The researchers used an algorithm to rapidly analyse large quantities of chemically modified RNA molecules and calculate how many differently folded conformations were present. This technique was used to identify a conserved structural switch in the ...

What The Article Says: How parents can identify whether their teens are vaping, how to help prevent it, and what to do if their teen is addicted are discussed in this JAMA Pediatrics Patient Page. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2020.6689) Editor's Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. INFORMATION: Media advisory: The full article is linked to this news release. Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2020.6689?guestAccessKey=8fe3a04c-4e0a-40f3-a883-916eaadb05bb&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=022221 ...

What The Study Did: This survey study looked at changes in abortion policies among states by examining legislation enacted between January 2017 and November 2020. Authors: Phillip M. Singer, Ph.D., of the University of Utah in Salt Lake City, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamainternmed.2020.8781) Editor's Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding ...

Diverse East Asians derive ancestry from a coastal expansion tens of thousands of years ago Researchers have long debated whether the peopling of East Asia by modern humans occurred mainly via a coastal or interior route. The answer is probably both. "Indigenous Andaman islanders of the Bay of Bengal, Indigenous Tibetans, ancient Taiwanese, and ancient and modern Japanese all derive ancestry from a deep shared lineage that split from other East Asian lineages more than 40,000 years ago," says David Reich, co-senior author of the study, who is a Professor of Genetics ...

Philadelphia, February 22, 2021 - Runt-related transcription factor 1 (RUNX1) has been linked to retinal neovascularization and the development of abnormal blood vessels, which result in vision loss in diabetic retinopathy. Now, scientists have found that RUNX1 inhibition presents a new therapeutic approach in the treatment of age-related macular degeneration (AMD), which is the leading cause of blindness in the elderly worldwide. Their END ...

Polished glass has been at the center of imaging systems for centuries. Their precise curvature enables lenses to focus light and produce sharp images, whether the object in view is a single cell, the page of a book, or a far-off galaxy. Changing focus to see clearly at all these scales typically requires physically moving a lens, by tilting, sliding, or otherwise shifting the lens, usually with the help of mechanical parts that add to the bulk of microscopes and telescopes. Now MIT engineers have fabricated a tunable "metalens" that can focus on objects at multiple depths, without changes to its physical position or shape. The lens is made not of solid glass but of a ...

Children exposed to air pollution, such as wildfire smoke and car exhaust, for as little as one day may be doomed to higher rates of heart disease and other ailments in adulthood, according to a new Stanford-led study. The analysis, published in Nature Scientific Reports, is the first of its kind to investigate air pollution's effects at the single cell level and to simultaneously focus on both the cardiovascular and immune systems in children. It confirms previous research that bad air can alter gene regulation in a way that may impact long-term health - a finding that could change the way medical experts and parents think about the air children ...

Abu Dhabi, UAE, February 22: By engineering common filter papers, similar to coffee filters, a team of NYU Abu Dhabi researchers have created high throughput arrays of miniaturized 3D tumor models to replicate key aspects of tumor physiology, which are absent in traditional drug testing platforms. With the new paper-based technology, the formed tumor models can be safely cryopreserved and stored for prolonged periods for on-demand drug testing use. These cryopreservable tumor models could provide the pharmaceutical industry with an easy and low cost method for investigating the outcomes of drug efficacy, potentially bolstering personalized ...

DURHAM, N.C. - The COVID-19 pandemic has heaped additional financial strains, childcare complications and other problems on already-burdened caregivers of children diagnosed with cancer, according to a study from researchers at Duke Health and other institutions. Surveying 360 parents and caregivers of children currently in treatment or still being monitored for cancer, the researchers found that half had to cancel or delay appointments, 77% reported increased feelings of anxiety and of those who had lost jobs or wages, 11% struggled to pay for basic needs. The survey findings appear online this month in the journal Pediatric Blood & Cancer. "Parents and caregivers ...

HOUSTON - (Feb. 22, 2021) -Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey Medical School (NJMS). Published online in the open-access journal mSystems, the research identifies a genetic mechanism that allows the TB-causing bacterium, Mycobacterium tuberculosis, to respond to stress rapidly and in manner that is "history-dependent," said corresponding author Oleg Igoshin, a professor of bioengineering at Rice. Researchers have long suspected that the ability of TB bacteria to remain dormant, sometimes for decades, ...