PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Study uncovers clues to COVID-19 using imaging

A global, multicenter study, led by UC, finds correlation between the severity of COVID-19 in the lungs and brain using CT/MRI scans

Study uncovers clues to COVID-19 using imaging
2021-03-12
(Press-News.org) Since the pandemic hit, researchers have been uncovering ways COVID-19 impacts other parts of the body, besides the lungs.

Now, for the first time, a visual correlation has been found between the severity of the disease in the lungs using CT scans and the severity of effects on patient's brains, using MRI scans. This research is published in the American Journal of Neuroradiology. It will be presented at the 59th annual meeting of the American Society of Neuroradiology (ASNR) and has also been selected as a semifinalist for that organization's Cornelius Dyke Award.

The results show that by looking at lung CT scans of patients diagnosed with COVID-19, physicians may be able to predict just how badly they'll experience other neurological problems that could show up on brain MRIs, helping improve patient outcomes and identify symptoms for earlier treatment.

CT imaging can detect illness in the lungs better than an MRI, another medical imaging technique. However, MRI can detect many problems in the brain, particularly in COVID-19 patients, that cannot be detected on CT images.

"We've seen patients with COVID-19 experience stroke, brain bleeds and other disorders affecting the brain," says lead author Abdelkader Mahammedi, MD, assistant professor of radiology at the University of Cincinnati and a UC Health neuroradiologist. "So, we're finding, through patient experiences, that neurological symptoms are correlating to those with more severe respiratory disease; however, little information has been available on identifying potential associations between imaging abnormalities in the brain and lungs in COVID-19 patients.

"Imaging serves as proof for physicians, confirming how an illness is forming and with what severity and helps in making final decisions about a patient's care."

In this study, which was conducted not only at UC, but also at large institutions in Spain, Italy and Brazil, researchers reviewed electronic medical records and images of hospitalized COVID-19 patients from March 3 to June 25, 2020. Patients who were diagnosed with COVID-19, experienced neurological issues and who had both lung and brain images available were included.

Of 135 COVID-19 patients with abnormal CT lung scans and neurological symptoms, 49, or 36%, were also found to develop abnormal brain scans and were more likely to experience stroke symptoms.

Mahammedi says this study will help physicians classify patients, based on the severity of disease found on their CT scans, into groups more likely to develop brain imaging abnormalities. He adds that this correlation could be important for implementing therapies, particularly in stroke prevention, to improve outcomes in patients with COVID-19.

"These results are important because they further show that severe lung disease from COVID-19 could mean serious brain complications, and we have the imaging to help prove it," says Mahammedi, who is also a member of the UC Gardner Neuroscience Institute. "Future larger studies are needed to help us understand the tie better, but for now, we hope these results can be used to help predict care and ensure that patients have the best outcomes."

INFORMATION:

This research was supported by the National Institutes of Health (the National Institute of Neurological Disorders and Stroke and National Institute on Aging) (NS103824, NS117643, NS100417, 1U01NS100699, U01NS110772). Researchers cite no conflict of interest.


[Attachments] See images for this press release:
Study uncovers clues to COVID-19 using imaging

ELSE PRESS RELEASES FROM THIS DATE:

Yeast epigenome map reveals details of gene regulation

2021-03-12
ITHACA, N.Y. - A new Penn State and Cornell study describes an effort to produce the most comprehensive and high-resolution map yet of chromosome architecture and gene regulation in yeast, a major step toward improving understanding of development, evolution and environmental responses in higher organisms. Specifically, the study mapped precise binding sites of more than 400 different chromosomal proteins in the yeast genome, most of which regulate the expression of genes. Yeast cells provide a simple model system with 6,000 genes, most of which are found in other organisms, including humans, making them excellent candidates for studying fundamental genetics and complex biological pathways. The paper, "A High-Resolution Protein Architecture of the Budding Yeast ...

Are there differences in the brains of autistic men and women?

2021-03-12
Around three times as many males are diagnosed with autism than females. This suggests that biological sex factors may play a role in the development and presentation of autism. Studies on the neurobiology (brain biology) of males and females with autism have begun to examine brain networks but results have been mixed. This is largely due to the limited availability of data from autistic females. In response, researchers from END ...

Extinction cascading through ecosystems could spell trouble for humans

2021-03-12
Humans rely on nature extensively for everything from food production to coastal protection, but those contributions might be more threatened than previously thought, according to new findings from the University of Colorado Boulder. This research, out today in Nature Communications, looked at three different coastal food webs that include those services provided to humans, or ecosystem services, and found that even if the services themselves aren't directly threatened, they can become threatened when other species around them go extinct--often called secondary ...

Using AI to assess surgical performance

2021-03-12
More than one million operations are performed in Switzerland every year. A surgeon's skill has a direct impact on the outcome of the operation. Training and experience, as well as momentary fatigue and other influencing factors all play a role. At present, skill is tested by experts, either directly during an operation or by evaluating video footage. This approach is very costly and only a limited number of experts are available. Moreover, the assessment may vary and is not always fully reproducible. For some time, attempts have been made to automate and objectify the assessment of surgeons' skills. Proof of feasibility The key result of the study is the proof of the fundamental feasibility of an ...

Confined magnetic colloidal system for controllable fluid transport

Confined magnetic colloidal system for controllable fluid transport
2021-03-12
Colloidal suspensions of microscopic particles show complex and interesting collective behaviors. In particular, the collective dynamics of colloids is fundamental and ubiquitous for materials assembly, robotic motion, microfluidic control, and in several biological scenarios. The collective dynamics of confined colloids can be completely different from that of free colloids: for instance, confined colloids can self-organize into vortex structures, coherent motion, or different phase behaviors. On one hand, due to the complexity of colloidal suspensions, how to finely tune the ...

New review explores effective sampling techniques for collecting airborne viruses and ultrafine part

2021-03-12
As the world continues to grapple with the COVID-19 pandemic, an international team of researchers have published a review of the best techniques to collect airborne aerosols containing viruses. In the review, which was published by the Science of the Total Environment journal, a team led by the University of Surrey concluded that the most effective way to collect and detect airborne pathogens, particularly viruses, was to use cyclone sampling techniques. For example, the sampler draws the air through the cyclone separator. It then uses centrifugal forces to collect the particles on a sterile cone containing the liquid collection vessel, such as DMEM (Dulbecco's minimal essential ...

Shedding light on perovskite films

Shedding light on perovskite films
2021-03-12
Photovoltaics decisively contributes to sustainable energy supply. The efficiency of solar cells in directly converting light energy into electrical energy depends on the material used. Metal-halide perovskites are considered very promising materials for solar cells of the next generation. With these semiconductors named after their special crystal structure, a considerable increase in efficiency was achieved in the past years. Meanwhile, perovskite solar cells have reached an efficiency of up to 25.5 percent, which is quite close to that of silicon ...

New proteins 'out of nothing'

New proteins out of nothing
2021-03-12
Proteins are the key component in all modern forms of life. Haemoglobin, for example, transports the oxygen in our blood; photosynthesis proteins in the leaves of plants convert sunlight into energy; and fungal enzymes help us to brew beer and bake bread. Researchers have long been examining the question of how proteins mutate or come into existence in the course of millennia. That completely new proteins - and, with them, new properties - can emerge practically out of nothing, was inconceivable for decades, in line with what the Greek philosopher Parmenides said: "Nothing can emerge from nothing" (ex nihilo nihil fit). Working with colleagues from the USA and ...

Evaluating the rehabilitation of an old mine waste rock pile

Evaluating the rehabilitation of an old mine waste rock pile
2021-03-12
The Cabeza de los Gatos waste rock pile, left from mining activities in the town of Tharsis (Huelva), underwent a rehabilitation process consisting of remodelling the slope of the pile, applying liming materials and then a layer of soil. Finally, trees and shrubs typical of the area were planted and a hydroseeding with a mixture of shrub and herbaceous seeds was applied. Twelve years later, a study led by researchers from IRNAS-CSIC, in collaboration with Sabina Rossini Oliva, a researcher from the University of Seville and the Environment and Water Agency of Andalusia (AMAYA), has proven the effectiveness of this sort of rehabilitation. "The results obtained show that the steps taken were successful. Now, ...

High emotional intelligence 'can help to identify fake news'

2021-03-12
People with high levels of emotional intelligence are less likely to be susceptible to 'fake news', according to research at the University of Strathclyde. The study invited participants to read a series of news items on social media and to ascertain whether they were real or fictitious, briefly describing the reasons for their answers. They were also asked to complete a test to determine their levels of emotional intelligence (EQ or emotional quotient) and were asked a number of questions when considering the veracity of each news item. Researchers found that those who identified the types of news correctly were most likely to score highly in the EQ tests. There was a similar correlation between correct identification and educational attainment. The ...

LAST 30 PRESS RELEASES:

Echidnapus identified from an ‘Age of Monotremes’

Semaglutide may protect kidney function in individuals with overweight or obesity and cardiovascular disease

New technique detects novel biomarkers for kidney diseases with nephrotic syndrome

Political elites take advantage of anti-partisan protests to disrupt politics

Tiny target discovered on RNA to short-circuit inflammation, UC Santa Cruz researchers find

Charge your laptop in a minute? Supercapacitors can help; new research offers clues

Scientists discover CO2 and CO ices in outskirts of solar system

Theory and experiment combine to shine a new light on proton spin

PKMYT1, a potential ‘Achilles heel’ of treatment resistant ER+ breast cancers with the poorest prognosis

PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors (PARs)

Virginia Tech researcher creates new tool to move tiny bioparticles

On repeat: Biologists observe recurring evolutionary changes, over time, in stick insects

Understanding a broken heart

Genetic cause of rare childhood immune disorders discovered

With wobbling stars, astronomers gauge mass of 126 exoplanets and find 15 new ones

High H5N1 influenza levels found in mice given raw milk from infected dairy cows

Study finds discreet shipping used to sell e-cigarettes to minors

African scientists call for equitable research partnerships to advance microbiome research

How COVID-19 'breakthrough' infections alter your immune cells

Virginia Tech entomologist sheds light on 250-year-old mystery of the German cockroach

Advancing skin science: explore Skin Ageing & Challenges 2024 Strategic Topics in Malta this November

Controlling water, transforming greenhouse gases

MSK Research Highlights, May 24, 2024

ASCO: Large precision oncology study identifies differences in prostate cancer genomics among a racially and ethnically diverse cohort of U.S. veterans

ASCO: Combination therapy significantly improves outcomes for patients with metastatic colorectal cancer

Euclid space mission releases first scientific results and new images of the cosmos

Sociodemographic heterogeneity in the associations of social isolation with mortality

COVID-19 admission rates and changes in care quality in us hospitals

Preterm and early-term delivery after heat waves in 50 US metropolitan areas

Research spotlight: Virtual scribes reduced physicians’ time spent on electronic health records

[Press-News.org] Study uncovers clues to COVID-19 using imaging
A global, multicenter study, led by UC, finds correlation between the severity of COVID-19 in the lungs and brain using CT/MRI scans