7T brain scans reveal potential early indicator of Alzheimer's

Novel research approach holds promise for early detection and treatment

2021-05-04

(Press-News.org) DALLAS (May 3, 2021) - Researchers from the Center for BrainHealth® at The University of Texas at Dallas are investigating a potential new early indicator of the decline toward Alzheimer's disease: measuring the energy metabolism of the living human brain using cutting-edge imaging techniques.

The scientists devised a unique way to illustrate energy consumption and reserves in the brain with phosphorus magnetic resonance spectroscopy using an ultra-high-field 7 Tesla MRI scanner. Their results suggest that neurological energy metabolism might be compromised in mild cognitive impairment (MCI), the stage of decline between healthy aging and more serious disease states like dementia and Alzheimer's.

Dr. Namrata Das, PhD'20, a program specialist and research neuroscientist in the END

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A study published today in Nature Communications shows that the drug rucaparib has been effective in treating certain types of ovarian cancers if used early in treatment, after a diagnosis, and before the cancer cells build up a resistance to chemotherapy. Rucaparib is in a relatively new class of drugs - Poly(ADP-ribose) polymerase or PARP inhibitors - which have been approved for therapy in ovarian cancers. This study provides insights into both how the cancers resist treatments, and which patients may respond favorably to the drug, said lead author Dr. Elizabeth Swisher, a UW Medicine ...

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Powering Discovery: A new expert panel report from the CCA

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