PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Risk of Parkinson disease among service members at Marine Corps Base Camp Lejeune

JAMA Neurology

2023-05-15
(Press-News.org) About The Study: This study of 340,000 service members found that the risk of Parkinson disease was 70% higher in veterans who were stationed at Marine Corps Base Camp Lejeune, North Carolina, during 1975-1985 when the water supply was contaminated with the solvent trichloroethylene and other volatile organic compounds. The findings suggest that exposure to trichloroethylene in water may increase the risk of Parkinson disease; millions worldwide have been and continue to be exposed to this ubiquitous environmental contaminant.

Authors: Samuel M. Goldman, M.D., M.P.H., of the University of California, San Francisco, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaneurol.2023.1168)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2023.1168?guestAccessKey=49157dd3-61b6-407f-b910-797c1a489b84&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051523

END


ELSE PRESS RELEASES FROM THIS DATE:

New study using novel approach for glioblastoma treatment shows promising results, extending survival

New study using novel approach for glioblastoma treatment shows promising results, extending survival
2023-05-15
TORONTO - A new international study published in Nature Medicine and presented as a late-breaking abstract at the American Association of Neurological Surgeons (AANS) annual conference, shows great promise for patients with glioblastoma. Drs. Farshad Nassiri and Gelareh Zadeh, neurosurgeons at the University Health Network (UHN) in Toronto, published the results of a Phase 1/2 clinical trial investigating the safety and effectiveness of a novel therapy which combines the injection of an oncolytic virus – a virus that targets and kills ...

Finding ‘vault’: Unravelling the mysteries of p62-bodies and the cellular recycling pathway

Finding ‘vault’: Unravelling the mysteries of p62-bodies and the cellular recycling pathway
2023-05-15
Our body functioning is delicately balanced between the synthesis and breakdown of various cellular components. When these cellular components grow old or get damaged, they are digested by a process called “autophagy”—literally, “self-eating.” This process not only helps in the elimination of toxic wastes, but also helps to deliver building blocks for the synthesis of new cellular macromolecules. Thus, autophagy serves as the body's cellular cleaning and recycling system.   Researchers have long been studying the ...

Comprehensive analysis of single plant cells provides new insights into natural product biosynthesis

Comprehensive analysis of single plant cells provides new insights into natural product biosynthesis
2023-05-15
Plants are impressive in their diversity, but especially in the variety of metabolites they produce. Many plant natural products are highly complex molecules, such as the alkaloids vincristine and vinblastine, which are produced by the Madagascar periwinkle Catharanthus roseus. These two substances are already indispensable in cancer therapy. Researchers are very interested in finding out which individual biosynthetic steps are required to form the complex molecules. "Currently, these compounds are still obtained in very small quantities from the plant's leaf extract. We can learn from the plant how this compound is produced and use this knowledge ...

Dementia study reveals how toxic proteins spread through brain

2023-05-15
Fresh insights into the spread of damaging proteins that build up in the brains of people with Alzheimer’s disease could hold the key to stopping the condition progressing, a study says. Researchers have discovered that synapses, which send essential signals through the brain, are also transporting toxic proteins known as tau around the brain. Large clumps of the protein tau – called tangles – form in brain cells and are one of the defining features of Alzheimer’s disease. As these tangles spread through the brain during the disease there is a decline in ...

Combined delivery of engineered virus with immunotherapy is safe and improves outcomes in subset of patients with glioblastoma

Combined delivery of engineered virus with immunotherapy is safe and improves outcomes in subset of patients with glioblastoma
2023-05-15
HOUSTON ― Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto. The study, published today in Nature Medicine, met its primary safety endpoint and demonstrated the combination was well tolerated overall with no dose-limiting toxicities. The study did not meet its primary efficacy endpoint of objective response rate, but ...

Mass General Brigham investigators identify new genetic variant protective against Alzheimer's disease

2023-05-15
A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment. In a publication today in Nature Medicine, an international team led by investigators from two Mass General Brigham hospitals — Massachusetts General Hospital (MGH) and Mass Eye and Ear — reports on a new case of a patient with a genetic predisposition for developing early-onset Alzheimer’s disease who remained cognitively intact until his late 60s. Through clinical assessments ...

Out of this world control on Ice Age cycles

Out of this world control on Ice Age cycles
2023-05-15
A research team, composed of climatologists and an astronomer, have used an improved computer model to reproduce the cycle of ice ages (glacial periods) 1.6 to 1.2 million years ago. The results show that the glacial cycle was driven primarily by astronomical forces in quite a different way than it works in the modern age. These results will help us to better understand the past, present, and future of ice sheets and the Earth’s climate.   Earth’s orbit around the Sun and its spin axis orientation change slowly over time, due to the pull of gravity from the Sun, the Moon, and other planets. These astronomical forces affect the environment on Earth due to changes in ...

Methylated cyclodextrin effectively prevents the crystallization of supersaturated drugs

Methylated cyclodextrin effectively prevents the crystallization of supersaturated drugs
2023-05-15
In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency. Solubilizing agents such as cyclodextrins (CDs) are commonly employed to enhance their solubility. CDs have a cyclic structure featuring a hydrophilic exterior and a hydrophobic cavity inside that can enclose drug molecules to form inclusion complexes. However, solubilization does not necessarily enhance drug adsorption in the body, since the solubilized drugs cannot ...

Translating science into impact: Cane-Bridge Foundation donates $1M to Boyce Thompson Institute for Innovative Translational Research Program

2023-05-15
Ithaca, NY (May 15, 2023) - Today, the Boyce Thompson Institute (BTI) is taking a significant step forward in its mission to bridge the gap between scientific discovery and real-world application. Thanks to a generous $1M gift from the Cane-Bridge Foundation, BTI has launched an innovative translational program called "Project Vault!" to propel plant science discoveries into applications that tackle global life science challenges.  "The Cane-Bridge Foundation's support is vital to accelerate ...

Latest research provides SwRI scientists close-up views of energetic particle jets ejected from the Sun

Latest research provides SwRI scientists close-up views of energetic particle jets ejected from the Sun
2023-05-15
SAN ANTONIO — May 15, 2023 —Southwest Research Institute (SwRI) scientists observed the first close-ups of a source of energetic particles expelled from the Sun, viewing them from just half an astronomical unit (AU), or about 46.5 million miles. The high-resolution images of the solar event were provided by ESA’s Solar Orbiter, a Sun-observing satellite launched in 2020. “In 2022, the Solar Orbiter detected six recurrent energetic ion injections. Particles emanated along the jets, a signature of magnetic reconnection involving ...

LAST 30 PRESS RELEASES:

Korea University study reveals hidden complexity in recurrent brain tumors

How an immune cell receptor dampens the fight against fungal infection

SeoulTech researchers uncover high PAHs in common foods

Precision in the pancreas: New test transforms hereditary pancreatitis diagnosis and care

Peer-reviewed study validates Mentavi’s online ADHD diagnostic evaluation in the Journal of Clinical Psychiatry

Machine embroidery encodes skin-like tension lines in textiles, enabling mass-customizable wearables

Customized gene-editing technology shows potential to treat lethal pediatric disease

Johns Hopkins researchers discover new methods for making smaller microchips

Durham University scientists play key role in testing superconducting materials for world’s largest fusion energy project

Drug-resistant fungus Candidozyma auris confirmed to spread rapidly in European hospitals: ECDC calls for urgent action

New evidence of long-distance travelers in Seddin during the Bronze Age

Newly dated 85-million-year-old dino eggs could improve understanding of Cretaceous climate

From noise to power: A symmetric ratchet motor discovery

Family-based intervention programs are insufficient to prevent childhood obesity, major study finds

Emotions expressed in real-time barrage comments relate to purchasing intentions and imitative behavior

Your genes could prune your gut bugs and protect you from disease

EMBARGOED MEDIA RELEASE: Breathlessness increases long-term mortality risk, Malawi study finds

Permeable inspection of pharmaceuticals goes in-line

Warming rivers in Alaska threaten Chinook salmon populations and Indigenous food security

New multi-disciplinary approach sheds light on the role of mitochondrial DNA mutations in cancer

Worms reveal just how cramped cells really are

Alzheimer’s disease digital resources lacking for Latinos, Hispanics in Los Angeles years after COVID-19, study finds

Chronic disease deaths decline globally, but progress is slowing

The Lancet: Chronic disease deaths decline globally, but progress is slowing

The Lancet: Parent-focused programs insufficient to prevent obesity in toddlers, finds meta-analysis; authors call for a re-think of childhood obesity prevention approaches

Study sheds light on hurdles faced in transforming NHS healthcare with AI

Astrocytic “brake” that blocks spinal cord repair identified

As farm jobs decline, food industry work holds steady

Kennesaw State researcher aiming to move AI beyond the cloud

Revolutionizing impedance flow cytometry with adjustable microchannel height

[Press-News.org] Risk of Parkinson disease among service members at Marine Corps Base Camp Lejeune
JAMA Neurology