PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Editorial: Turning the tide on obesity?

2023-08-03
(Press-News.org) In an Editorial, Cynthia Bulik and Andrew Hardaway highlight the recent advances in medical treatments for obesity and weight loss. “With the emergence of new, highly effective weight-loss drugs, might the ‘fat decades’ become a closed chapter in the history of public health?” ask the authors. The “obesity epidemic” is a global health concern, with more than a billion people affected by obesity and many more overweight. Although various environmental, biological, and behavioral factors have been implicated in obesity, few consistently effective treatments exist for the disease. Recently, however, new weight-loss drugs, like glucagon-like peptide-1 (GLP-1) receptor agonists, originally developed for diabetes, have shown promise in promoting weight loss by reducing appetite and increasing satiety signals from the gut to the brain. However, these drugs are expensive and can potentially create and widen health disparities as obesity disproportionally affects marginalized racial, ethnic, and socioeconomic communities. Moreover, weight regain is common once the medication is discontinued, functionally rendering them “forever” drugs with currently unknown potential long-term side effects. “Tackling these issues is essential to prevent unintended consequences brought on by the meteoric success of these drugs,” write Bulik and Hardaway. “We are entering an era in which effective obesity treatments exist for the first time.”

END


ELSE PRESS RELEASES FROM THIS DATE:

Compensation for damages can and should address social and cultural impacts

2023-08-03
In this Policy Forum, Robin Gregory and colleagues highlight how a suite of methodological approaches can be used to bring less tangible social and cultural losses that marginalized groups incur into the formal compensation assessment framework. “Though the issues and approaches we describe are applicable in many contexts,” the authors write, “we illustrate them … with a focus on Indigenous communities, for whom the neglect of social and cultural losses in assessments of compensation ...

Adult tropical trees of the same species grow farther apart than factors like seed dispersal limits can explain

2023-08-03
Tropical trees distance themselves from members of their own species more than they do other species, a new study shows. What’s more, trees of the same species exist at distances farther apart than would be expected by chance or the limits of seed dispersal. The results reveal pervasive within-species spatial repulsion in adult trees, providing new insights into the ecological dynamics that stabilize species diversity and enable the exceptionally high diversity of tropical forests. Tropical forests host an unusually high diversity of tree species. For example, some tropical forests contain more than 250 tree species per hectare. However, how hundreds of species coexist on relatively small ...

A gut hormone for controlling appetite doubles as an immune regulator for the fungal microbiome

2023-08-03
Peptide YY (PYY), a hormone produced by gut endocrine cells that was already known to control appetite, also plays an important role in maintaining the balance of fungi in the digestive system of mammals, according to new research from the University of Chicago. In a study published this week in Science, researchers found that specialized immune cells in the small intestine called Paneth cells express a form of PYY that prevents the fungus Candida albicans from turning into its more virulent form. PYY was already known to be produced by endocrine cells in the gut as a hormone that signals satiety, or when an animal has had enough to eat. The new research shows that it also ...

New, simple and accessible method creates potency-increasing structure in drugs

New, simple and accessible method creates potency-increasing structure in drugs
2023-08-03
UNIVERSITY PARK, Pa. — Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and require highly reactive—potentially explosive—ingredients. Now, a team of researchers from Penn State has identified and demonstrated a safe, efficient and practical way to create cyclopropanes on a wide variety of molecules using a previously undescribed chemical process. With additional development, the new method—described ...

Study finds a surprising new role for a major immune regulator

2023-08-03
CAMBRIDGE, MA -- A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms. STING is primarily on the lookout for DNA, which can indicate either a foreign invader such as a virus or damage to the host tissue or cell. When STING detects that danger signal, it can turn on at least three different pathways — one leading to interferon production, one to non-canonical autophagy (involved in recycling cell components and clearing pathogens), and a third to formation of the inflammasome, a complex of proteins that activates ...

Winter storms over Labrador Sea influence Gulf Stream system

2023-08-03
The Gulf Stream, which brings warm water from the Gulf of Mexico to Europe and keeps the climate mild, is only part of a larger system of oceanic currents called the Atlantic Meridional Overturning Circulation, or AMOC for short. It runs through the Atlantic like a giant climate machine: as warm water from the tropics is transported northwards at the surface, the current reverses in the North Atlantic – the water cools, becomes heavier and flows south at depth. Where exactly these sinking processes take place is the subject of current research, and recent measurement programmes have located them to the east of Greenland. ...

Doctors, medical professionals, and artificial intelligence: Innocent bystanders or vicious culprits? – a hot topic of the AI & Medicine 2024 World Congress in Paris, France

Doctors, medical professionals, and artificial intelligence: Innocent bystanders or vicious culprits? – a  hot topic of the AI & Medicine 2024 World Congress in Paris, France
2023-08-03
Paris, France – August 3, 2023 – The First International Congress on Artificial Intelligence and Medicine, AI & Medicine 2024, is set to take place on April 11-12, 2024, in Paris, France. Building on the success of IA & Néphrologie 2023, the conference aims to bridge the gap between cutting-edge technology and health care. AI & Medicine 2024 aims to inform medical professionals about the capabilities of advanced machine learning techniques, and simultaneously raise awareness within the tech industry regarding the unique challenges and requirements of the healthcare sector. The congress will offer a platform to discuss the current applications of AI in diagnostics, ...

A spinout’s biggest competitor may be the parent company, not other entrepreneurs

2023-08-03
Spinouts, or new ventures started by employees leaving a parent firm, often outperform other types of new firms. But a new study published in Strategic Management Journal finds that when parent firms identify and implement ideas internally, they outperform spinouts. For example, if employees at Microsoft leave the parent and start their own spinout in the competing industry, the spinout potentially needs to compete against a new establishment formed by Microsoft in the same industry. New ventures by former employees often have an edge over competitors because of the knowledge transfer from their ...

FSU researcher finds potential new tool for early identification of dementia risk

FSU researcher finds potential new tool for early identification of dementia risk
2023-08-03
Research at the Florida State University College of Medicine has identified a potential low-cost method for predicting if a person is at risk of developing dementia. By analyzing data from nearly 13,000 subjects who participated in a long-term aging study, researchers found that an interviewer’s rating of a cognitively healthy person’s memory successfully predicted the likelihood of developing dementia over a 15-year period. Their findings will be published in the Journal of Alzheimer’s Disease. “Our findings show that interviewers ...

Current takes a surprising path in quantum material

2023-08-03
ITHACA, N.Y. -- Cornell researchers used magnetic imaging to obtain the first direct visualization of how electrons flow in a special type of insulator, and by doing so they discovered that the transport current moves through the interior of the material, rather than at the edges, as scientists had long assumed. The finding provides new insights into the electron behavior in so-called quantum anomalous Hall insulators and should help settle a decades-long debate about how current flows in more general quantum Hall insulators. These insights will inform the development of topological materials for next-generation quantum devices. The team’s paper, “Direct ...

LAST 30 PRESS RELEASES:

Impact of pollutants on pollinators, and how neural circuits adapt to temperature changes

Researchers seek to improve advanced pain management using AI for drug discovery

‘Neutron Nexus’ brings universities, ORNL together to advance science

Early release from NEJM Evidence

UMass Amherst astronomer leads science team helping to develop billion-dollar NASA satellite mission concept

Cultivating global engagement in bioengineering education to train students skills in biomedical device design and innovation

Life on Earth was more diverse than classical theory suggests 800 million years ago, a Brazilian study shows

International clean energy initiative launches global biomass resource assessment

How much do avoidable deaths impact the economy?

Federal government may be paying twice for care of veterans enrolled in Medicare Advantage plans

New therapeutic target for cardiac arrhythmias emerges

UC Irvine researchers are first to reveal role of ophthalmic acid in motor function control

Moffitt study unveils the role of gamma-delta T cells in cancer immunology

Drier winter habitat impacts songbirds’ ability to survive migration

Donors enable 445 TPDA awards to Neuroscience 2024

Gut bacteria engineered to act as tumor GPS for immunotherapies

Are auditory magic tricks possible for a blind audience?

Research points to potential new treatment for aggressive prostate cancer subtype

Studies examine growing US mental health safety net

Social risk factor domains and preventive care services in US adults

Online medication abortion direct-to-patient fulfillment before and after the Dobbs v Jackson decision

Black, Hispanic, and American Indian adolescents likelier than white adolescents to be tested for drugs, alcohol at pediatric trauma centers

Pterosaurs needed feet on the ground to become giants

Scientists uncover auditory “sixth sense” in geckos

Almost half of persons who inject drugs (PWID) with endocarditis will die within five years; women are disproportionately affected

Experimental blood test improves early detection of pancreatic cancer

Groundbreaking wastewater treatment research led by Oxford Brookes targets global challenge of toxic ‘forever chemicals’

Jefferson Health awarded $2.4 million in PCORI funding

Cilta-cel found highly effective in first real-world study

Unleashing the power of generative AI on smart collaborative innovation network platform to empower research and technology innovation

[Press-News.org] Editorial: Turning the tide on obesity?