PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Red blood cell transfusion in the ICU

JAMA

2023-10-12
(Press-News.org) About The Study: Red blood cell (RBC) transfusion was common in patients admitted to 233 intensive care units in 30 countries between 2019 and 2022, with high variability across centers in transfusion practices. Although many different clinical reasons and triggers were stated for RBC transfusion, the three most common reasons (low hemoglobin level, active bleeding, hemodynamic instability) and triggers (hypotension, tachycardia, no physiological trigger affected the decision to transfuse) were largely overlapping in all regions. 

Authors: Alexander P. J. Vlaar, M.D., Ph.D., M.B.A., of Amsterdam University Medical Centers in Amsterdam, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2023.20737)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2023.20737?guestAccessKey=84f29d05-795c-4b6a-b31a-f4cbcdf4238f&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=101223

END


ELSE PRESS RELEASES FROM THIS DATE:

Small-volume blood collection tubes to reduce transfusions in intensive care

2023-10-12
About The Study: This randomized trial in 25 adult medical-surgical intensive care units (ICUs) in Canada found that the transition from standard-volume to small-volume tubes for blood collection in the ICU may reduce red blood cell transfusion without impacting biospecimen sufficiency for laboratory analysis.  Authors: Deborah M. Siegal, M.D., M.Sc., of McMaster University in Hamilton, Ontario, Canada, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2023.20820) Editor’s Note: Please see the article for ...

The burden of lung cancer in women compared with men in the US

2023-10-12
About The Study: Based on high-quality population-based data, this study found that the higher lung cancer incidence in women than in men has not only continued in individuals younger than 50 years but also now extends to middle-aged adults as younger women with a high risk of the disease enter older age. Reasons for this shift are unclear because the prevalence and intensity of smoking are not higher in younger women compared with men except for a slightly elevated prevalence among those born in the 1960s.  Authors: Ahmedin Jemal, D.V.M., Ph.D., of the American Cancer Society in Atlanta, is the corresponding author.  To access the embargoed study: ...

Race and ethnicity and primary language in emergency department triage

2023-10-12
About The Study: In this study of 249,000 visits to seven academic and community hospital emergency departments, patients who identified as Black, Hispanic, and Other race and ethnicity were assigned less acute Emergency Severity Index scores than their white peers despite having received more involved physician workups, suggesting some degree of mistriage. Clinical decision support systems might reduce these disparities but would require careful calibration to avoid replicating bias.  Authors: Joshua W. Joseph, M.D., M.S., ...

Big blood savings: large trial in JAMA shows taking less blood for lab testing reduces transfusions in intensive care

Big blood savings: large trial in JAMA shows taking less blood for lab testing reduces transfusions in intensive care
2023-10-12
A world-first clinical trial published in JAMA could provide an easy way to save tens of thousands of units of blood every year in Canada and much more worldwide. The trial, which involved more than 27,000 patients in 25 adult intensive care units (ICUs) across Canada, showed that taking less blood for lab tests using “small-volume” tubes reduced the need for almost one blood transfusion for every 10 patients. Most hospitals use standard tubes that automatically draw four to six milliliters (ml) of blood, but a typical laboratory test requires less than 0.5 ml of blood, meaning the rest (more ...

We can respond to verbal stimuli while sleeping

We can respond to verbal stimuli while sleeping
2023-10-12
Sleep is generally defined as a period during which the body and mind are at rest—as if disconnected from the world. However, a new study led by Delphine Oudiette, Isabelle Arnulf, and Lionel Naccache at Paris Brain Institute shows that the frontier between wakefulness and sleep is much more porous than it seems. The researchers have shown that ordinary sleepers can pick up verbal information transmitted by a human voice and respond to it by contracting their facial muscles. This astonishing ability occurs intermittently during almost all stages of sleep—like windows of connection with the outside world were temporarily opened on this occasion. These new findings ...

Flagship individuals can boost conservation

Flagship individuals can boost conservation
2023-10-12
“Flagship” individual animals like Cecil the lion or Freya the walrus can boost conservation, new research suggests. Much-loved species like pandas and polar bears are widely used in conservation campaigns. However, a new study argues that individual animals or plants can also be used as flagships, with enormous potential to raise awareness and mobilise public support. The recent outcry over the felling of the “Sycamore Gap” tree in the UK demonstrates the power of individual plants or animals in public opinion. “Flagship individuals typically share some common characteristics,” ...

Letting go of an extra weight to control sleeping sickness

Letting go of an extra weight to control sleeping sickness
2023-10-12
Letting go of an extra weight to control sleeping sickness   A new study led by Luísa Figueiredo, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), and published today in the scientific journal Nature Microbiology* found a new strategy by the host to cope with Trypanosoma brucei infection. Trypanosoma brucei is the parasite that causes sleeping sickness in humans, and nagana in cattle, which remain a public health ...

Simulations of ‘backwards time travel’ can improve scientific experiments

2023-10-12
Physicists have shown that simulating models of hypothetical time travel can solve experimental problems that appear impossible to solve using standard physics. If gamblers, investors and quantum experimentalists could bend the arrow of time, their advantage would be significantly higher, leading to significantly better outcomes.  Researchers at the University of Cambridge have shown that by manipulating entanglement – a feature of quantum theory that causes particles to be intrinsically linked – they can simulate what could happen if one could travel backwards in time. So that gamblers, investors and ...

Extraordinary fossil find reveals details about the weight and diet of extinct saber-toothed marsupial

Extraordinary fossil find reveals details about the weight and diet of extinct saber-toothed marsupial
2023-10-12
Recent paleontological explorations in the Tatacoa Desert in Colombia led to the recovery of the most complete skeleton of a "saber-toothed marsupial” discovered in northern South America. The specimen belongs to the species Anachlysictis gracilis, which is part of a group of extinct predatory mammals known as sparassodonts, that lived in South America during the Cenozoic, after the extinction of the dinosaurs. This species lived approximately 13 million years ago in the area known among paleontologists as ‘La Venta’, in the current La Tatacoa desert, a tropical dry forest that “at that time was a tropical rainforest, similar to the current Amazon,” said ...

Traumatic memories can rewire the brain

Traumatic memories can rewire the brain
2023-10-12
Okazaki, Japan – Scientists have long speculated about the physical changes that occur in the brain when a new memory is formed. Now, research from the National Institute for Physiological Sciences (NIPS) has shed light on this intriguing neurological mystery. In a study recently published in Nature Communications, The research team has succeeded in detecting the brain neuronal networks involved in trauma memory by using a novel method that combines optical and machine-learning-based approaches, capturing the complex changes that occur during memory formation and uncovering the mechanisms by which trauma memories ...

LAST 30 PRESS RELEASES:

Impact of pollutants on pollinators, and how neural circuits adapt to temperature changes

Researchers seek to improve advanced pain management using AI for drug discovery

‘Neutron Nexus’ brings universities, ORNL together to advance science

Early release from NEJM Evidence

UMass Amherst astronomer leads science team helping to develop billion-dollar NASA satellite mission concept

Cultivating global engagement in bioengineering education to train students skills in biomedical device design and innovation

Life on Earth was more diverse than classical theory suggests 800 million years ago, a Brazilian study shows

International clean energy initiative launches global biomass resource assessment

How much do avoidable deaths impact the economy?

Federal government may be paying twice for care of veterans enrolled in Medicare Advantage plans

New therapeutic target for cardiac arrhythmias emerges

UC Irvine researchers are first to reveal role of ophthalmic acid in motor function control

Moffitt study unveils the role of gamma-delta T cells in cancer immunology

Drier winter habitat impacts songbirds’ ability to survive migration

Donors enable 445 TPDA awards to Neuroscience 2024

Gut bacteria engineered to act as tumor GPS for immunotherapies

Are auditory magic tricks possible for a blind audience?

Research points to potential new treatment for aggressive prostate cancer subtype

Studies examine growing US mental health safety net

Social risk factor domains and preventive care services in US adults

Online medication abortion direct-to-patient fulfillment before and after the Dobbs v Jackson decision

Black, Hispanic, and American Indian adolescents likelier than white adolescents to be tested for drugs, alcohol at pediatric trauma centers

Pterosaurs needed feet on the ground to become giants

Scientists uncover auditory “sixth sense” in geckos

Almost half of persons who inject drugs (PWID) with endocarditis will die within five years; women are disproportionately affected

Experimental blood test improves early detection of pancreatic cancer

Groundbreaking wastewater treatment research led by Oxford Brookes targets global challenge of toxic ‘forever chemicals’

Jefferson Health awarded $2.4 million in PCORI funding

Cilta-cel found highly effective in first real-world study

Unleashing the power of generative AI on smart collaborative innovation network platform to empower research and technology innovation

[Press-News.org] Red blood cell transfusion in the ICU
JAMA