PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

BU researcher receives K01 grant to study how nutrition impacts TB incidence, mortality

2023-11-30
(Press-News.org) (Boston)—Pranay Sinha, MD, assistant professor of medicine at Boston University Chobanian & Avedisian School of Medicine, has received a National Institutes of Health Mentored Research Scientist Development Award (K01). These awards provide support and protected time (three to five years) for an intensive, supervised, career development experience in the biomedical, behavioral or clinical sciences, leading to research independence.

As part of this honor, Sinha has received a five-year, $640,508 National Institute of Allergy and Infectious Diseases grant for his project, “Nutritional Interventions to End Tuberculosis (TB) among persons with HIV in India-- NUTRIENT-India.” The award will be used to help quantify the long-term impact of nutritional interventions on TB incidence and mortality among persons with and without TB in India. In addition, Sinha will also be supported by a career investment award from the school’s department of medicine.

India has the third-highest number of persons with HIV. One-quarter of deaths among persons with HIV are due to TB. Transmission from HIV-negative persons likely fuels this epidemic, and undernutrition is the leading risk factor for TB among them.

Sinha believes that population-scale nutritional interventions would reduce TB incidence and mortality among persons with and without HIV. “The NUTRIENT-India study will define the most cost-effective nutritional interventions. Additionally, it will inform policymakers on why they must address this critical TB risk factor that keeps TB entrenched in India and how they can intervene while making maximal use of available resources,” explains Sinha who also is an infectious disease physician at Boston Medical Center.

Sinha attended the University of Virginia School of Medicine, completed his residency training at Yale-New Haven Hospital, and is currently completing a master’s degree in health policy and management at Harvard TH Chan School of Public Health. He has been involved in TB research since 2014 and has conducted epidemiological studies in South Africa, Benin, Togo, and India.

END


ELSE PRESS RELEASES FROM THIS DATE:

Researchers show an old law still holds for quirky quantum materials

Researchers show an old law still holds for quirky quantum materials
2023-11-30
Long before researchers discovered the electron and its role in generating electrical current, they knew about electricity and were exploring its potential. One thing they learned early on was that metals were great conductors of both electricity and heat. And in 1853, two scientists showed that those two admirable properties of metals were somehow related: At any given temperature, the ratio of electronic conductivity to thermal conductivity was roughly the same in any metal they tested. This so-called Wiedemann-Franz law has held ever since – except in quantum materials, where electrons stop behaving as individual particles and glom together into a sort of electron soup. ...

Pickier dogs have pickier brains

Pickier dogs have pickier brains
2023-11-30
Dogs’ food preferences are mirrored in their brain activity, particularly within their caudate nuclei -a brain region associated with reward processing, a new study combining behavioural and neuroimaging data by researchers from the Department of Ethology, Eötvös Loránd University (Hungary) and Symrise Pet Food (France) finds. The study, which seamlessly blends behavioral observations with advanced neuroimaging techniques, offers novel insights into the influence of food quality on dogs' motivation. This work has been published in Scientific Reports. Similar to people, ...

Despite pressures facing young families, parents take precious moments to play with their babies

2023-11-30
Four in five primary caregivers of nine-month-old babies reported cuddling, talking and playing with their little one several times a day, in England's first national long-term study of babies in over two decades, led by UCL (University College London).  More than half engaged in physical or turn-taking play, singing, pretend games and noisy play with their babies several times a day – activities which were linked to improved early language development. Around three quarters showed their babies picture ...

Combined use of alcohol and THC can affect rat brains, study finds

Combined use of alcohol and THC can affect rat brains, study finds
2023-11-30
The increased legalization of cannabis over the past several years can potentially increase its co-use with alcohol. Concerningly, very few studies have looked at the effects of these two drugs when used in combination. In a series of new studies, researchers at the University of Illinois Urbana-Champaign used rats to understand how brain structure and behavior can change when cannabis and alcohol are taken together. Most researchers have studied the effects of either alcohol or THC (delta-9-tetrahydrocannabinol), the primary psychoactive drug in cannabis, alone. However, when people, especially adolescents, use these drugs, ...

Tis the season to recognize chocolate: researchers highlight high quality cacao in Colombia

2023-11-30
Scientists are working to protect the unique qualities of cacao beans grown in the Buenaventura region on the Pacific coast of Colombia. In a study published in the Journal of the Science of Food and Agriculture, researchers from the Colombian Corporation for Agricultural Research (AGROSAVIA) have examined a wealth of metrics to uncover the complex interactions between environmental factors and cacao quality. In a pioneering move, they have proposed that Buenaventura should be designated as a new Denomination of Origin (DO) for cacao trees. This is a legal recognition given to products that originate ...

Straining memory leads to new computing possibilities

Straining memory leads to new computing possibilities
2023-11-30
By strategically straining materials that are as thin as a single layer of atoms, University of Rochester scientists have developed a new form of computing memory that is at once fast, dense, and low-power. The researchers outline their new hybrid resistive switches in a study published in Nature Electronics. Developed in the lab of Stephen M. Wu, an assistant professor of electrical and computer engineering and of physics, the approach marries the best qualities of two existing forms of resistive switches used for memory: memristors and phase-change materials. Both forms have been explored for their advantages over ...

Antarctica's ancient ice sheets foreshadow dynamic changes in Earth’s future

2023-11-30
MADISON – Nineteen million years ago, during a time known as the early Miocene, massive ice sheets in Antarctica rapidly and repeatedly grew and receded. The Miocene is widely considered a potential analog for Earth's climate in the coming century, should humanity remain on its current carbon emissions trajectory. Identifying how and why Antarctica's major ice sheets behaved the way they did in the early Miocene could help inform understanding of the sheets' behavior under a warming climate. Together, the ice sheets lock a volume of water equivalent to more than 50 meters of sea level rise and influence ocean currents that affect marine food webs and regional climates. ...

Modular chimeric cytokine receptors improve CAR T–cell therapy for solid tumors

Modular chimeric cytokine receptors improve CAR T–cell therapy for solid tumors
2023-11-30
(MEMPHIS, Tenn. – November 30, 2023) Immunotherapy using modified chimeric antigen receptor (CAR) T cells has greatly improved survival rates for pediatric patients with relapsed and recurrent leukemia. However, these therapies are not as effective in treating solid tumors and can have significant toxicity. Findings from St. Jude Children’s Research Hospital showed that adding a modular chimeric cytokine receptor to CAR T cells increased their efficacy in multiple solid tumor models. The study was published today in Nature Biomedical Engineering.   “We designed modular chimeric cytokine receptors and showed that ...

Climate: why disinformation is so persistent

2023-11-30
Melting of glaciers, rising sea levels, extreme heat waves: the consequences of climate change are more visible than ever, and the scientific community has confirmed that humans are responsible. Yet studies show that a third of the population still doubts or disputes these facts. The cause is disinformation spread by certain vested interests. To try and prevent this phenomenon, a team from the University of Geneva (UNIGE) has developed and tested six psychological interventions on nearly 7,000 participants from twelve countries. The research, published in ...

Early body contact develops premature babies' social skills

Early body contact develops premature babies social skills
2023-11-30
Skin-to-skin contact between parent and infant during the first hours after a very premature birth helps develop the child's social skills. This is according to a new study published in JAMA Network Open by researchers from Karolinska Institutet and others. The study also shows that fathers may play a more important role than previous research has shown. In current practice, very premature babies are usually placed in an incubator to keep them warm and to stabilize them during the first hours after birth. In the “Immediate parent-infant skin-to-skin study” (IPISTOSS), 91 premature babies born at 28 to 33 weeks were randomized to either ...

LAST 30 PRESS RELEASES:

Here's why seafarers have little confidence in autonomous ships

MYC amplification in metastatic prostate cancer associated with reduced tumor immunogenicity

The gut can drive age-associated memory loss

Enhancing gut-brain communication reversed cognitive decline, improved memory formation in aging mice

Mothers exposure to microbes protect their newborn babies against infection

How one flu virus can hamper the immune response to another

Researchers uncover distinct tumor “neighborhoods”, with each cell subtype playing a specific role, in aggressive childhood brain cancer

Researchers develop new way to safely insert gene-sized DNA into the genome

Astronomers capture birth of a magnetar, confirming link to some of universe’s brightest exploding stars

New photonic device, developed by MIT researchers, efficiently beams light into free space

UCSB researcher bridges the worlds of general relativity and supernova astrophysics

Global exchange of knowledge and technology to significantly advance reef restoration efforts

Vision sensing for intelligent driving: technical challenges and innovative solutions

To attempt world record, researchers will use their finding that prep phase is most vital to accurate three-point shooting

AI is homogenizing human expression and thought, computer scientists and psychologists say

Severe COVID-19, flu facilitate lung cancer months or years later, new research shows

Housing displacement, employment disruption, and mental health after the 2023 Maui wildfires

GLP-1 receptor agonist use and survival among patients with type 2 diabetes and brain metastases

Solid but fluid: New materials reconfigure their entire crystal structure in response to humidity

New research reveals how development and sex shape the brain

New discovery may improve kidney disease diagnosis in black patients

What changes happen in the aging brain?

Pew awards fellowships to seven scientists advancing marine conservation

Turning cancer’s protein machinery against itself to boost immunity

Current Pharmaceutical Analysis releases Volume 22, Issue 2 with open access research

Researchers capture thermal fluctuations in polymer segments for the first time

16-year study finds major health burden in single‑ventricle heart

Disposable vapes ban could lead young adults to switch to cigarettes, study finds

Adults with concurrent hearing and vision loss report barriers and challenges in navigating complex, everyday environments

Breast cancer stage at diagnosis differs sharply across rural US regions

[Press-News.org] BU researcher receives K01 grant to study how nutrition impacts TB incidence, mortality