PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Occupational sitting time, leisure physical activity, and all-cause and cardiovascular disease mortality

JAMA Network Open

2024-01-19
(Press-News.org)

About The Study: In this study involving 481,000 individuals over a mean follow-up period of nearly 13 years, individuals who predominantly engaged in sitting at work exhibited a higher risk of mortality from all causes and cardiovascular disease compared with those who predominantly did not sit. Individuals who predominantly sit at work would need to engage in an additional 15 to 30 minutes of physical activity per day to mitigate this increased risk and reach the same level of risk as individuals who predominantly do not sit at work.

Authors: Chi-Pang Wen, M.D., Ph.D., of the National Health Research Institutes in Miaoli County, Taiwan, and Min-Kuang Tsai, Ph.D., of Taipei Medical University in New Taipei City, Taiwan, are the corresponding authors. 

 To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2023.50680)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.50680?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=011924

END



ELSE PRESS RELEASES FROM THIS DATE:

Timing of maternal COVID-19 vaccine and antibody concentrations in infants born preterm

2024-01-19
About The Study: In this prospective cohort study of 220 pregnant individuals with preterm and full-term deliveries, receipt of three or more compared with two doses of COVID-19 vaccine before delivery resulted in 10-fold higher cord anti-Spike antibody levels. Maternal antibody concentration appeared more important than delivery gestational age in determining cord anti-Spike antibody levels. The number of doses and timing considerations for COVID-19 vaccine in pregnancy should include individuals at risk for preterm delivery. Authors: Alisa Kachikis, M.D., M.S., of the University ...

When are opioid prescription limits effective in reducing prescription length?

2024-01-19
Study analyzed a West Virginia policy that tailored duration limits to a patient’s clinical setting  Researchers found a 27-57% reduction in prescription length with the tailored policy Additional research is needed on potential consequences of limits, such as use of illicit opioids for pain relief  CHICAGO --- Many states have passed new laws that place restrictions on the duration of first-time opioid prescriptions to help address the opioid epidemic. While most laws are one-size-fits-all, policies more tailored to the patient, such as their age or clinical setting (outpatient clinic, emergency room, etc.), were more effective ...

Bacterial meningitis damages one in three children for life

Bacterial meningitis damages one in three children for life
2024-01-19
One in three children who suffer from bacterial meningitis live with permanent neurological disabilities due to the infection. This is according to a new epidemiological study led by Karolinska Institutet and published in leading medical journal JAMA Network Open.  For the first time, researchers have identified the long-term health burden of bacterial meningitis. The bacterial infection can currently be cured with antibiotics, but it often leads to permanent neurological impairment. And since children are often affected, ...

McMaster researchers create instruction manual to detect rare cells that could unlock secrets to allergies

2024-01-19
Researchers with McMaster University have created the instruction manual that will help scientists across the globe find hard to detect B cells. Led by PhD student Alyssa Phelps and Department of Medicine Assistant Professor Josh Koenig, researchers wanted to chart a path to finding these cells as part of their work in understanding food allergies. Their work was published in the journal Nature Protocols on Jan. 19, 2024. B cells are a type of immune cell that makes antibodies. These cells help fight conditions like cancer and infections but can also cause autoimmune diseases and allergies. "One of the big problems with trying to study these B ...

Rice’s Amanda Marciel wins NSF CAREER Award

Rice’s Amanda Marciel wins NSF CAREER Award
2024-01-19
HOUSTON – (Jan. 19, 2024) – Amanda Marciel describes her current research, supported by a CAREER Award from the National Science Foundation, as an effort to understand and make “really soft, stretchable stuff.” Expressed more formally, she works at the molecular level to design branch elastomers that return to their original shape after being stretched. “What I’m doing is creating synthetic networks that have a gel-like softness and are highly elastic for such applications as stretchable ...

JMC|Insilico Medicine nominates novel AI-driven PHD inhibitor targeting anemia

JMC|Insilico Medicine nominates novel AI-driven PHD inhibitor targeting anemia
2024-01-19
Clinical stage generative artificial intelligence (AI)-driven biotechnology company InSilico Medicine (“InSilico”), today announced that the Journal of Medicinal Chemistry, an ACS Publications journal focusing on critical studies about molecular structure and biological activity, has published the company’s discovery of a novel PHD inhibitor for the treatment of anemia. The academic breakthrough is powered by Chemistry42, its proprietary generative chemistry platform consisting of more than 40 selected generative models.   As suggested in previous studies, the inhibition ...

JMC | Insilico Medicine presents the discovery of the potent and selective MYT1 inhibitors for the treatment of cancer through generative AI

JMC | Insilico Medicine presents the discovery of the potent and selective MYT1 inhibitors for the treatment of cancer through generative AI
2024-01-19
Insilico Medicine(“Insilico”), a clinical stage generative artificial intelligence (AI)-driven drug discovery company, recently published an early research that it has identified MYT1 as a promising new therapeutic target for breast and gynecological cancer, and discovered a series of novel, potent, and highly selective inhibitors specifically targeting MYT1. These findings were supported by Insilico’s AI-driven generative biology and chemistry engine and published in the Journal of Medicinal Chemistry in Dec 2023.   Across ...

Professors Yoon-Kyoung Cho elected as Member of National Academy of Engineering of Korea!​

Professors Yoon-Kyoung Cho elected as Member of National Academy of Engineering of Korea!​
2024-01-19
Professor Yoon-Kyoung Cho from the Department of Biomedical Engineering at UNIST has been elected as a member of the National Academy of Engineering of Korea (NAEK), the most prestigious organization in the field of engineering in Korea. On January 4, the National Academy of Engineering of Korea (NAEK) announced the election of 50 new members, comprising 25 academic and 25 industrial figures, in recognition of their distinguished and ongoing achievements in original research. Membership in NAEK is considered one of the highest professional distinctions for engineers. Professor Cho’s name appeared ...

New study reveals critical role of FAM3c in breast cancer progression

New study reveals critical role of FAM3c in breast cancer progression
2024-01-19
A groundbreaking study conducted by Professor Jiyoung Park and her research team in the Department of Biological Sciences at UNIST has identified FAM3C, a metabolism-regulating signaling molecule produced by cancer-associated adipocytes (CAAs), as a key regulator of breast cancer progression within the tumor microenvironment (TME). The findings, published in the prestigious academic journal Cancer Research, shed light on the potential for targeted therapies in the treatment of breast cancer. The study demonstrates that overexpression of FAM3C in cultured adipocytes significantly reduces cell death in both adipocytes and co-cultured breast cancer ...

New medicine can create a new life for diabetes patients – without needles!

New medicine can create a new life for diabetes patients – without needles!
2024-01-19
There are approximately 425 million people worldwide with diabetes. Approximately 75 million of these inject themselves with insulin daily. Now they may soon have a new alternative to syringes or insulin pumps. Scientists have found a new way to supply the body with smart insulin. The new insulin can be eaten by taking a capsule or even better, within a piece chocolate. Inside these we find tiny nano-carriers to which the insulin is encapsulated. The particles are 1/10,000th the width of a human hair and so small that you cannot even see them under a normal microscope. “This ...

LAST 30 PRESS RELEASES:

Oldest modern shark mega-predator swam off Australia during the age of dinosaurs

Scientists unveil mechanism behind greener ammonia production

Sharper, straighter, stiffer, stronger: Male green hermit hummingbirds have bills evolved for fighting

Nationwide awards honor local students and school leaders championing heart, brain health

Epigenetic changes regulate gene expression, but what regulates epigenetics?

Nasal drops fight brain tumors noninvasively

Okayama University of Science Ranked in the “THE World University Rankings 2026” for the Second Consecutive Year

New study looks at (rainforest) tea leaves to predict fate of tropical forests

When trade routes shift, so do clouds: Florida State University researchers uncover ripple effects of new global shipping regulations

Kennesaw State assistant professor receives grant to improve shelf life of peptide- and protein-based drugs

Current heart attack screening tools are not optimal and fail to identify half the people who are at risk

LJI scientists discover how T cells transform to defend our organs

Brain circuit controlling compulsive behavior mapped

Atoms passing through walls: Quantum tunneling of hydrogen within palladium crystal

Observing quantum footballs blown up by laser kicks

Immune cells ‘caught in the act’ could spur earlier detection and prevention of Type 1 Diabetes

New membrane sets record for separating hydrogen from CO2

Recharging the powerhouse of the cell

University of Minnesota research finds reducing inflammation may protect against early AMD-like vision loss

A mulching film that protects plants without pesticides or plastics

New study highlights key findings on lung cancer surveillance rates

Uniform reference system for lightweight construction methods

Improve diet and increase physical activity at the same time to limit weight gain, study suggests

A surprising insight may put a charge into faster muscle injury repair

Scientists uncover how COVID-19 variants outsmart the immune system

Some children’s tantrums can be seen in the brain, new study finds

Development of 1-Wh-class stacked lithium-air cells

UVA, military researchers seek better ways to identify, treat blast-related brain injuries

AMS Science Preview: Railways and cyclones; pinned clouds; weather warnings in wartime

Scientists identify a molecular switch to a painful side effect of chemotherapy

[Press-News.org] Occupational sitting time, leisure physical activity, and all-cause and cardiovascular disease mortality
JAMA Network Open