Occupational sitting time, leisure physical activity, and all-cause and cardiovascular disease mortality
JAMA Network Open
2024-01-19
(Press-News.org)
About The Study: In this study involving 481,000 individuals over a mean follow-up period of nearly 13 years, individuals who predominantly engaged in sitting at work exhibited a higher risk of mortality from all causes and cardiovascular disease compared with those who predominantly did not sit. Individuals who predominantly sit at work would need to engage in an additional 15 to 30 minutes of physical activity per day to mitigate this increased risk and reach the same level of risk as individuals who predominantly do not sit at work.
Authors: Chi-Pang Wen, M.D., Ph.D., of the National Health Research Institutes in Miaoli County, Taiwan, and Min-Kuang Tsai, Ph.D., of Taipei Medical University in New Taipei City, Taiwan, are the corresponding authors.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2023.50680)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.50680?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=011924
END
ELSE PRESS RELEASES FROM THIS DATE:
2024-01-19
About The Study: In this prospective cohort study of 220 pregnant individuals with preterm and full-term deliveries, receipt of three or more compared with two doses of COVID-19 vaccine before delivery resulted in 10-fold higher cord anti-Spike antibody levels. Maternal antibody concentration appeared more important than delivery gestational age in determining cord anti-Spike antibody levels. The number of doses and timing considerations for COVID-19 vaccine in pregnancy should include individuals at risk for preterm delivery.
Authors: Alisa Kachikis, M.D., M.S., of the University ...
2024-01-19
Study analyzed a West Virginia policy that tailored duration limits to a patient’s clinical setting
Researchers found a 27-57% reduction in prescription length with the tailored policy
Additional research is needed on potential consequences of limits, such as use of illicit opioids for pain relief
CHICAGO --- Many states have passed new laws that place restrictions on the duration of first-time opioid prescriptions to help address the opioid epidemic.
While most laws are one-size-fits-all, policies more tailored to the patient, such as their age or clinical setting (outpatient clinic, emergency room, etc.), were more effective ...
2024-01-19
One in three children who suffer from bacterial meningitis live with permanent neurological disabilities due to the infection. This is according to a new epidemiological study led by Karolinska Institutet and published in leading medical journal JAMA Network Open.
For the first time, researchers have identified the long-term health burden of bacterial meningitis. The bacterial infection can currently be cured with antibiotics, but it often leads to permanent neurological impairment. And since children are often affected, ...
2024-01-19
Researchers with McMaster University have created the instruction manual that will help scientists across the globe find hard to detect B cells.
Led by PhD student Alyssa Phelps and Department of Medicine Assistant Professor Josh Koenig, researchers wanted to chart a path to finding these cells as part of their work in understanding food allergies. Their work was published in the journal Nature Protocols on Jan. 19, 2024.
B cells are a type of immune cell that makes antibodies. These cells help fight conditions like cancer and infections but can also cause autoimmune diseases and allergies.
"One of the big problems with trying to study these B ...
2024-01-19
HOUSTON – (Jan. 19, 2024) – Amanda Marciel describes her current research, supported by a CAREER Award from the National Science Foundation, as an effort to understand and make “really soft, stretchable stuff.”
Expressed more formally, she works at the molecular level to design branch elastomers that return to their original shape after being stretched.
“What I’m doing is creating synthetic networks that have a gel-like softness and are highly elastic for such applications as stretchable ...
2024-01-19
Clinical stage generative artificial intelligence (AI)-driven biotechnology company InSilico Medicine (“InSilico”), today announced that the Journal of Medicinal Chemistry, an ACS Publications journal focusing on critical studies about molecular structure and biological activity, has published the company’s discovery of a novel PHD inhibitor for the treatment of anemia. The academic breakthrough is powered by Chemistry42, its proprietary generative chemistry platform consisting of more than 40 selected generative models.
As suggested in previous studies, the inhibition ...
2024-01-19
Insilico Medicine(“Insilico”), a clinical stage generative artificial intelligence (AI)-driven drug discovery company, recently published an early research that it has identified MYT1 as a promising new therapeutic target for breast and gynecological cancer, and discovered a series of novel, potent, and highly selective inhibitors specifically targeting MYT1. These findings were supported by Insilico’s AI-driven generative biology and chemistry engine and published in the Journal of Medicinal Chemistry in Dec 2023.
Across ...
2024-01-19
Professor Yoon-Kyoung Cho from the Department of Biomedical Engineering at UNIST has been elected as a member of the National Academy of Engineering of Korea (NAEK), the most prestigious organization in the field of engineering in Korea.
On January 4, the National Academy of Engineering of Korea (NAEK) announced the election of 50 new members, comprising 25 academic and 25 industrial figures, in recognition of their distinguished and ongoing achievements in original research. Membership in NAEK is considered one of the highest professional distinctions for engineers. Professor Cho’s name appeared ...
2024-01-19
A groundbreaking study conducted by Professor Jiyoung Park and her research team in the Department of Biological Sciences at UNIST has identified FAM3C, a metabolism-regulating signaling molecule produced by cancer-associated adipocytes (CAAs), as a key regulator of breast cancer progression within the tumor microenvironment (TME). The findings, published in the prestigious academic journal Cancer Research, shed light on the potential for targeted therapies in the treatment of breast cancer.
The study demonstrates that overexpression of FAM3C in cultured adipocytes significantly reduces cell death in both adipocytes and co-cultured breast cancer ...
2024-01-19
There are approximately 425 million people worldwide with diabetes. Approximately 75 million of these inject themselves with insulin daily. Now they may soon have a new alternative to syringes or insulin pumps. Scientists have found a new way to supply the body with smart insulin.
The new insulin can be eaten by taking a capsule or even better, within a piece chocolate.
Inside these we find tiny nano-carriers to which the insulin is encapsulated. The particles are 1/10,000th the width of a human hair and so small that you cannot even see them under a normal microscope.
“This ...
LAST 30 PRESS RELEASES:
[Press-News.org] Occupational sitting time, leisure physical activity, and all-cause and cardiovascular disease mortality
JAMA Network Open