(Press-News.org) About The Study: This cohort study of Japanese older adults identified that upward and downward socioeconomic status transitions were associated with risk of dementia and the length of dementia-free periods over the lifespan. The results may be useful to understand the association between social mobility and healthy longevity.
Corresponding Author: To contact the corresponding author, Hiroyasu Iso, Ph.D., email iso@pbhel.med.osaka-u.ac.jp.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.12303)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.12303?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052124
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
END
Socioeconomic status transition throughout life and risk of dementia
JAMA Network Open
2024-05-21
ELSE PRESS RELEASES FROM THIS DATE:
Climbing the social ladder slows dementia, Japanese study reveals
2024-05-21
Osaka, Japan – Upward social mobility may ward off dementia, according to a new study. Dementia, a collective term for conditions marked by memory loss and diminished cognitive functioning, strains healthcare systems and devastates quality of life for patients and their families. Research thus far has found correlations between socioeconomic status (SES) – Parent’s asset, education level, income, and work status – and susceptibility to dementia, and SES changes throughout a person’s life, known as social mobility, seem to influence this risk; however, scientific ...
Researchers discover hidden step in dinosaur feather evolution
2024-05-21
Scientists discover ‘zoned development’ in dinosaur skin, with zones of reptile-style scales and zones of bird-like skin with feathers
New dinosaur skin fossil found to be composed of silica – the same as glass
Discovery sheds light on evolution from scales to feathers
Palaeontologists at University College Cork (UCC) in Ireland have discovered that some feathered dinosaurs had scaly skin like reptiles today, thus shedding new light on the evolutionary transition from scales to feathers.
The researchers studied a new specimen of the feathered dinosaur Psittacosaurus from the early Cretaceous ...
Studies reveal cell-by-cell changes caused when pig hearts and kidneys are transplanted into humans
2024-05-21
Surgical teams at NYU Langone Health performed the world’s first genetically modified pig kidney transplants into a human body in September and November 2021, and then transplanted two pig hearts in the summer of 2022. These procedures were done in patients declared dead based on neurologic criteria (decedents) and maintained on ventilators with the consent of their families. Demonstrating the field’s progress, NYU Langone in April 2024 transplanted a pig kidney into a living patient.
Now two new analyses, one published online on May 17 in Nature Medicine and the other May ...
SRI earns FDA Orphan Drug Designation for pancreatic cancer
2024-05-21
SRI’s Targeted Antigen Loaded Liposomes (TALL) — a treatment that expands the benefits of immunotherapy such as check-point inhibitors — has been granted Orphan Drug Designation (ODD) for pancreatic ductal adenocarcinoma (PDAC) by the U.S. Federal Drug Administration (FDA).
As a result, SRI’s future strategic partners can gain tax credits for qualified clinical trials and potentially receive market exclusivity for a period of seven years after the drug’s approval, among other benefits.
“FDA's orphan drug designation brings worthy attention to the demonstrated impact of SRI's TALL biotherapeutic for pancreatic cancer,” said Kathlynn Brown, ...
A new gene-editing system tackles complex diseases
2024-05-21
The human genome consists of around 3 billion base pairs and humans are all 99.6% identical in their genetic makeup. That small 0.4% accounts for any difference between one person and another. Specific combinations of mutations in those base pairs hold important clues about the causes of complex health issues, including heart disease and neurodegenerative diseases like schizophrenia.
Current methods to model or correct mutations in live cells are inefficient, especially when multiplexing — installing multiple point mutations simultaneously across the genome. Researchers from the University of California San Diego ...
Tracking down toxic metals from tobacco smoke
2024-05-21
Cigarette smoke has been studied for years, revealing a multitude of contaminants, including toxic metals. But exactly which of those metals can be traced to secondhand or thirdhand smoke? Solving this problem has been a challenge for the research community because many of the metals found in tobacco smoke could also come from industrial or naturally occurring pollutants contaminating indoor and outdoor air.
Now, a recent study by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) has identified 28 trace metals in tobacco smoke. The findings reported in the journal ...
Clarifying the cellular mechanisms underlying periodontitis with an improved animal model
2024-05-21
TMDU researchers have developed a technique that allows a detailed analysis of periodontitis development over time
Tokyo, Japan – Periodontal disease, represented by periodontitis, is the leading cause of tooth loss and affects close to one in five adults worldwide. In most cases, this condition occurs as a result of an inflammatory response to bacterial infection of the tissue around teeth. As the condition worsens, the gums begin to pull away, exposing teeth roots and bone. Notably, the incidence of periodontitis becomes more prevalent with age and with populations worldwide living ...
Age, race impact AI performance on digital mammograms
2024-05-21
OAK BROOK, Ill. – In a study of nearly 5,000 screening mammograms interpreted by an FDA-approved AI algorithm, patient characteristics such as race and age influenced false positive results. The study’s results were published today in Radiology, a journal of the Radiological Society of North America (RSNA).
“AI has become a resource for radiologists to improve their efficiency and accuracy in reading screening mammograms while mitigating reader burnout,” said Derek L. Nguyen, M.D., assistant professor at Duke University in Durham, North Carolina. ...
SwRI leads courses at 2024 Society of Tribologists & Lubrication Engineers Annual Meeting
2024-05-21
SAN ANTONIO — May 21, 2024 —As a leader in fuels and lubricants research, Southwest Research Institute is home to a world-class tribology laboratory and expert staff that are developing advanced techniques and technology to study wear, friction and lubrication. SwRI tribologists will share their expertise at the 2024 Society of Tribologists and Lubrication Engineers (STLE) Annual Meeting May 19-23 in Minneapolis.
The STLE Annual Meeting and Exhibition invites members of the lubricant industry ...
Hope for a cure for visceral leishmaniasis, an often fatal infectious disease
2024-05-21
Hope for a cure for visceral leishmaniasis, an often fatal infectious disease
A discovery by Simona Stäger’s team could help come up with a treatment to the most serious form of leishmaniasis.
Leishmaniasis is a tropical disease affecting a growing number of people worldwide. Each year, between 700,000 and 1 million new cases are reported. Caused by a protozoan parasite of the genus Leishmania, which is transmitted to humans by the simple bite of a sand fly, leishmaniasis comprises three clinical forms, of which the visceral ...
LAST 30 PRESS RELEASES:
New discovery sheds light on evolutionary crossroads of vertebrates
Aortic hemiarch reconstruction safely matches complex aortic arch reconstruction for acute dissection in older adults
Destination Earth digital twin to improve AI climate and weather predictions
Late-breaking study finds comparable long-term survival between two leading multi-arterial CABG strategies
Lymph node examination should be expanded to accurately assess cancer spread in patients with lung cancer
Study examines prediction of surgical risk in growing population of adults with congenital heart disease
Novel radiation therapy QA method: Monte Carlo simulation meets deep learning for fast, accurate epid transmission dose generation
A 100-fold leap into the unknown: a new search for muonium conversion into antimuonium
A new approach to chiral α-amino acid synthesis - photo-driven nitrogen heterocyclic carbene catalyzed highly enantioselective radical α-amino esterification
Physics-defying discovery sheds new light on how cells move
Institute for Data Science in Oncology announces new focus-area lead for advancing data science to reduce public cancer burden
Mapping the urban breath
Waste neem seeds become high-performance heat batteries for clean energy storage
Scientists map the “physical genome” of biochar to guide next generation carbon materials
Mobile ‘endoscopy on wheels’ brings lifesaving GI care to rural South Africa
Taming tumor chaos: Brown University Health researchers uncover key to improving glioblastoma treatment
Researchers enable microorganisms to build molecules with light
Laws to keep guns away from distressed individuals reduce suicides
Study shows how local business benefits from city services
RNA therapy may be a solution for infant hydrocephalus
Global Virus Network statement on Nipah virus outbreak
A new molecular atlas of tau enables precision diagnostics and drug targeting across neurodegenerative diseases
Trends in US live births by race and ethnicity, 2016-2024
Sex and all-cause mortality in the US, 1999 to 2019
Nasal vaccine combats bird flu infection in rodents
Sepsis study IDs simple ways to save lives in Africa
“Go Red. Shop with Heart.” to save women’s lives and support heart health this February
Korea University College of Medicine successfully concludes the 2025 Lee Jong-Wook Fellowship on Infectious Disease Specialists Program
Girls are happiest at school – for good reasons
Researchers from the University of Maryland School of Medicine discover genetic ancestry is a critical component of assessing head and neck cancerous tumors
[Press-News.org] Socioeconomic status transition throughout life and risk of dementiaJAMA Network Open






