(Press-News.org) BOSTON—Older women with low bone density are more likely to experience their first hip fracture in their 60s compared to older ages, according to research being presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
“Older women experience an increased risk of fragility hip fractures. These are hip fractures with minimal trauma or due to a fall from a standing height, and they are often deadly and disabling,” said Avica Atri, M.D., an Internal Medicine resident physician at Jefferson Einstein Hospital in Philadelphia, Pa. “As the population over 60 swells in the United States, a large proportion of women will be at an increased risk of such fractures.”
Atri and her colleagues sought to understand how osteoporosis in the hip might increase the risk for fractures over time in specific age groups.
They used National Health and Nutrition Examination Survey (NHANES) data to identify women in the U.S. aged 60 or older with low bone mineral density (T-score ≤ -1) at the femur neck, based on DEXA scans from 2009-2018.
“Among these women, we found that the average bone mineral density in the hip declined along with a rise in the burden of osteoporosis, which increased from 18% to 21%,” Atri said. “However, this did not translate to an increase in the number of fragility hip fractures during this period and interestingly, there were 50% fewer self-reported fragility hip fractures in the 10-year span of the study.” The researchers found no significant increase in osteoporosis treatment during this time.
They also found that the number of women aged older than 70 years who experienced their first fragility hip fracture decreased during the study, compared with women aged 60-69 years. The women aged 60-70 years self-reported a first hip fracture 50% more. The researchers believe this might be due to prevention efforts already in place for the population aged above 70 years.
These findings, Atri said, highlight the need for earlier bone health awareness through routine primary care office visits. She also suggests additional measures to improve patient education on the benefits of nutrition, exercise, fall prevention, screening and treatment to curb these disparities.
“As the prevalence of osteoporosis nationally shows a worsening trend based on the analysis of the NHANES data, women are more likely to experience their first fragility hip fracture in their 60s rather than at older ages,” Atri said. “It’s never too early to think about bone health.”
# # #
Endocrinologists are at the core of solving the most pressing health problems of our time, from diabetes and obesity to infertility, bone health, and hormone-related cancers. The Endocrine Society is the world’s oldest and largest organization of scientists devoted to hormone research and physicians who care for people with hormone-related conditions.
The Society has more than 18,000 members, including scientists, physicians, educators, nurses and students in 122 countries. To learn more about the Society and the field of endocrinology, visit our site at www.endocrine.org. Follow us on Twitter at @TheEndoSociety and @EndoMedia.
END
More women report hip fractures earlier in life
2024-06-02
ELSE PRESS RELEASES FROM THIS DATE:
Cutting-edge robotics: Introducing the hybrid-driven origami gripper
2024-06-02
In an impressive leap forward for robotics technology, researchers from Shanghai Jiao Tong University have unveiled a novel hybrid-driven origami gripper, designed to tackle the challenge of grasping and manipulating objects with unprecedented versatility and precision. This innovative device, highlighted in a recent study published in Cyborg Bionic Systems, promises to reshape the capabilities of robotic systems in industries ranging from manufacturing to healthcare.
The newly developed gripper utilizes a combination of pneumatic and cable-driven mechanisms to control an origami-inspired structure, allowing for adjustable finger stiffness and variable finger lengths. This sophisticated ...
The future of drug testing: Vascularized organ-on-a-chip technologies
2024-06-02
In an era marked by rapid technological advancement in biomedical engineering, a groundbreaking development is set to revolutionize our approach to drug testing and disease modeling. Researchers from Shanghai University and the University of California Los Angeles have made significant strides in the field of in vitro vascularized organ-on-a-chip systems, offering a promising alternative to traditional methods that rely heavily on animal testing and simplistic two-dimensional cell cultures.
The organ-on-a-chip technology mimics human organs on a microscale by cultivating cells in a controlled microenvironment that simulates the 3D structure and physiological ...
New male birth control gel takes effect sooner than similar contraceptive methods
2024-06-02
BOSTON—A novel male contraceptive gel combining two hormones, segesterone acetate (named Nestorone) and testosterone, suppresses sperm production faster than similar experimental hormone-based methods for male birth control, according to a new study.
Results from an ongoing multicenter phase 2b clinical trial will be presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston.
“The development of a safe, highly effective and reliably reversible contraceptive method for ...
Study finds potentially treatable factors to improve symptoms in men stopping illicit steroids
2024-06-02
BOSTON—Men who illicitly used steroids to boost muscle size and physical performance and have stopped in the past year have impaired sexual function compared with men currently using steroids, according to a study being presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
Having a psychiatric diagnosis and stopping steroids was associated with greater impairment in sexual function, the researchers found.
“It is important to recognize the symptoms that men experience within the first year of stopping ...
Hot flashes in menopausal women may signal increased risk for heart and metabolic issues
2024-06-02
BOSTON—Women experiencing moderate-to-severe vasomotor symptoms face a three times greater risk for metabolic-dysfunction-associated steatotic liver disease (MASLD) compared to those with mild symptom severity, according to research being presented Monday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
Vasomotor symptoms include hot flashes or night sweats—symptoms that have become synonymous with menopause.
“This research is significant as it contributes ...
Revolutionizing robotics: Integrating actuation and sensing for smarter soft robots
2024-06-02
The world of robotics is witnessing a transformative shift with the rise of soft robotics, which offers unparalleled flexibility and adaptability in various applications, from medical interventions to intricate rescue operations. A groundbreaking review article by Zhou et al. published in Cyborg Bionic Systems in 2024, sheds light on this evolution, highlighting the crucial integration of actuation and sensing technologies that pave the way for truly intelligent soft robots.
Soft robots, unlike their rigid counterparts, are made from materials that mimic the mechanical properties of living tissues, allowing them to move and adapt with a life-like grace. This capability makes ...
Almost 20% of breast cancer survivors may experience excess weight gain
2024-06-02
BOSTON—Almost one out of five breast cancer survivors may experience weight gain of more than 10%, suggests a study presented Monday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. A number of factors are associated with excessive weight gain, the researchers found.
Factors associated with more than 10% weight gain included a lower weight, younger age, and more advanced cancer stage at cancer diagnosis; hormone-positive breast cancer; mutations of the BRCA2 gene; undergoing more aggressive breast surgery; and the use of chemotherapy and endocrine therapy, the study found.
“Weight ...
Immunotherapy significantly increases the number of patients free from bowel cancer
2024-06-02
An immunotherapy drug given before surgery instead of chemotherapy meant that over ten times more patients with a certain genetic profile were cancer free after surgery, according to clinical trial results presented by researchers at UCL and UCLH.
The findings, presented at the American Society of Clinical Oncology (ASCO) Annual Meeting 2024, are interim results from the NEOPRISM-CRC phase II clinical trial assessing whether the immunotherapy drug pembrolizumab can improve outcomes for patients with stage two or stage three MMR deficient/MSI-High bowel cancer. The ...
Stepped palliative care for patients with advanced lung cancer
2024-06-02
About The Study: A stepped-care model, with palliative care visits occurring only at key points in patients’ cancer trajectories and using a decrement in quality of life to trigger more intensive palliative care exposure, resulted in fewer palliative care visits without diminishing the benefits for patients’ quality of life. While stepped palliative care was associated with fewer days in hospice, it is a more scalable way to deliver early palliative care to enhance patient-reported outcomes.
Quote from corresponding author Jennifer S. Temel, M.D.:
“This study demonstrates that early palliative ...
Trial reveals benefits of ‘stepped’ palliative care for patients with advanced lung cancer
2024-06-02
BOSTON – A new study led by investigators from Mass General Cancer Center, a founding member of the Mass General Brigham healthcare system, reveals the effectiveness of more scalable ways of delivering palliative care to patients with advanced lung cancer. The findings were highlighted at the American Society of Clinical Oncology’s annual meeting and are published in JAMA.
The study, led by Jennifer S. Temel, MD of the Mass General Cancer Center, assessed the effectiveness of stepped palliative care, in which all patients receive palliative care for their condition, but with a minimum of required contact with a specialty-trained clinician. ...