(Press-News.org) The Brain & Behavior Research Foundation (BBRF) is hosting a free webinar, “Neurocognitively-Defined Subtypes in Bipolar Disorder: A Path to More Personalized Treatments” on Tuesday, June 11, 2024, at 2:00 pm ET. The presenter, Katherine E. Burdick, PhD, is the Jonathan F. Borus, MD Distinguished Chair in Psychiatry and the Vice Chair for Research in Psychiatry at Brigham and Women’s Hospital. She is the Director of the Mood and Psychosis Research Program at BWH and a Professor at Harvard Medical School. Dr. Burdick received the Colvin Prize for Outstanding Achievement in Mood Disorders Research from BBRF in 2021. The host, Jeffrey Borenstein, M.D., is the President & CEO of the Brain & Behavior Research Foundation, and host of the public television series Healthy Minds. Register today to hear their enlightening discussion on bipolar disorder.
Bipolar disorder (BD) is a mental illness that causes unusual shifts in a person’s mood, energy, activity levels, and concentration. These shifts can make it difficult to carry out day-to-day tasks. BD is a complex disease that varies notably in different patients, clinically, cognitively, and in terms of brain function. The reliance on traditional disease classifications (e.g., DSM categorical diagnoses) has yielded an incomplete understanding of the illness. To overcome this, we have applied empirical approaches to classify individuals along neurobiologically relevant dimensions into more homogenous subgroups. These novel subtypes can then be further characterized on the basis of behavioral and biological markers to identify modifiable risk factors that contribute to poor outcomes in people with BD. It is our hope that this approach will make possible a more personalized approach to treatment.
About Brain & Behavior Research Foundation
The Brain & Behavior Research Foundation awards research grants to develop improved treatments, cures, and methods of prevention for mental illness. These illnesses include addiction, ADHD, anxiety, autism, bipolar disorder, borderline personality disorder, depression, eating disorders, OCD, PTSD, and schizophrenia, as well as research on suicide prevention. Since 1987, the Foundation has awarded more than $450 million to fund more than 5,400 leading scientists around the world. 100% of every dollar donated for research is invested in research. BBRF operating expenses are covered by separate foundation grants. BBRF is the producer of the Emmy® nominated public television series Healthy Minds with Dr. Jeffrey Borenstein, which aims to remove the stigma of mental illness and demonstrate that with help, there is hope.
END
Neurocognitively-defined subtypes in bipolar disorder: a path to more personalized treatments
A free webinar from the Brain & Behavior Research Foundation
2024-06-04
ELSE PRESS RELEASES FROM THIS DATE:
Shining a light on molecules: L-shaped metamaterials can control light direction
2024-06-04
UNIVERSITY PARK, Pa. — Polarized light waves spin clockwise or counterclockwise as they travel, with one direction behaving differently than the other as it interacts with molecules. This directionality, called chirality or handedness, could provide a way to identify and sort specific molecules for use in biomedicine applications, but researchers have had limited control over the direction of the waves — until now.
Using metamaterials, a team of electrical engineering researchers from Penn State and the University of Nebraska-Lincoln ...
Wistar scientists develop novel antibody treatment for kidney cancer
2024-06-04
PHILADELPHIA — (June 04, 2024) — Advanced clear cell renal cell carcinoma (ccRCC) is a deadly form of kidney cancer with few treatment options; even with new immunotherapies, only around one in 10 patients ultimately survive.
Antibody therapies called bispecific T cell engagers (BTEs) have emerged as effective treatments for some blood cancers but have been more difficult to develop for solid tumors. While clinically successful, first-generation BTEs suffer a short half-life. Now, Wistar scientists have built upon BTE technology to develop new and improved recombinant and synthetic ...
Virus that causes COVID-19 can remain in sperm for 110 days after infection
2024-06-04
Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that SARS-CoV-2, the virus that causes COVID-19, can remain in the sperm of patients for up to 90 days after hospital discharge and up to 110 days after the initial infection, reducing semen quality. The study is reported in an article published in the journal Andrology. The authors suggest that people who plan to have children should observe a period of “quarantine” after recovering ...
Researchers use machine learning to detect defects in additive manufacturing
2024-06-04
Researchers at the University of Illinois Urbana-Champaign have developed a new method for detecting defects in additively manufactured components.
One of the most important tasks in any factory is to determine whether a manufactured component is free of defects. In additive manufacturing (3D printing), it can be particularly challenging to find defects, because additive manufacturing can make components that have complex three-dimensional shapes and important internal features that are not easily observed.
The novel technology uses deep machine ...
Rare disease’s DNA-damaging mutation could have consequences for more common conditions
2024-06-04
TREX1 is a gene that is supposed to direct the maintenance of the entire body’s DNA, but new research shows that when people are born with mutated TREX1, it causes catastrophic damage to the DNA over time, resulting in a deadly rare disease called retinal vasculopathy with cerebral leukoencephalopathy (RVCL). Published in Nature Communications, the research was led by teams at the Perelman School of Medicine at the University of Pennsylvania and the Brain Research Institute at Niigata University in Japan.
While it was already known that a mutation in TREX1 was behind RVCL, the mechanism by which ...
Exploring three frontiers in marine biomass and blue carbon capture
2024-06-04
A new study offers first-time insights into three emerging climate innovations to safeguard or increase the carbon naturally captured by ocean and coastal ecosystems: rapid interventions to save the Great Barrier Reef, satellite-tracked kelp beds in the deep ocean, and seagrass nurseries in the United Kingdom. The research, published in Environmental Science & Policy and co-authored by leading climate scholars at Boston University, Aarhus University, and the University of Sussex Business School, advances knowledge of understudied interventions in marine ...
Microscope system sharpens scientists’ view of neural circuit connections
2024-06-04
The brain’s ability to learn comes from “plasticity,” in which neurons constantly edit and remodel the tiny connections called synapses that they make with other neurons to form circuits. To study plasticity, neuroscientists seek to track it at high resolution across whole cells, but plasticity doesn’t wait for slow microscopes to keep pace and brain tissue is notorious for scattering light and making images fuzzy. In a paper in Scientific Reports, a collaboration of MIT engineers and neuroscientists describes a new microscopy system designed for fast, clear, and frequent imaging of the living brain.
The system, ...
VHIO researchers demonstrate the utility of high-sensitivity liquid biopsy to predict and monitor response to immunotherapy
2024-06-04
The liquid biopsy technique applied in this work is based on the sequencing of the entire tumor genome from 138 patients and the monitoring of mutations in the blood. This approach achieves high sensitivity in detecting the tumor signal in the blood (1/1,000,000 DNA molecules), and the patterns found reflect how patients respond to immunotherapy.
This study is part of the Comprehensive Program of Cancer Immunotherapy and Immunology (CAIMI) at VHIO, funded by the BBVA Foundation, and is co-led by Dr Rodrigo Toledo, head of the Biomarkers and Clonal Dynamics Group at the Vall d’Hebron Institute of Oncology (VHIO), ...
Muscle disorder caused by key protein mutations uncovered in new study
2024-06-04
A recent study has found that the SMCHD1 protein plays a key role in controlling how genes are processed, which affects the progression of Facioscapulohumeral Muscular Dystrophy (FSHD). This discovery about SMCHD1's function in gene regulation is important because it opens new possibilities for developing targeted therapeutic strategies to combat the disease. By understanding more about how SMCHD1 works, scientists can explore new ways to fight the disease.
A recent study by MD-PhD student Eden Engal under the guidance of Dr. Yotam Drier and ...
Observing ultrafast photoinduced dynamics in a halogen-bonded supramolecular system
2024-06-04
Researchers uncover how the halogen bond can be exploited to direct sequential dynamics in the multi-functional crystals, offering crucial insights for developing ultrafast-response times for multilevel optical storage.
Halogen bonds are intermolecular interactions that arise from the attraction between a halogen atom (group 17 elements in the periodic table) and another atom with lone pairs, more generally a molecular entity with high electron density. Understanding the distinctive and highly directional nature of halogen bonds is crucial for crystal engineering and studying ...
LAST 30 PRESS RELEASES:
The Lancet: Without immediate action nearly 260 million people in the USA predicted to have overweight or obesity by 2050
Diabetes medication may be effective in helping people drink less alcohol
US over 40s could live extra 5 years if they were all as active as top 25% of population
Limit hospital emissions by using short AI prompts - study
UT Health San Antonio ranks at the top 5% globally among universities for clinical medicine research
Fayetteville police positive about partnership with social workers
Optical biosensor rapidly detects monkeypox virus
New drug targets for Alzheimer’s identified from cerebrospinal fluid
Neuro-oncology experts reveal how to use AI to improve brain cancer diagnosis, monitoring, treatment
Argonne to explore novel ways to fight cancer and transform vaccine discovery with over $21 million from ARPA-H
Firefighters exposed to chemicals linked with breast cancer
Addressing the rural mental health crisis via telehealth
Standardized autism screening during pediatric well visits identified more, younger children with high likelihood for autism diagnosis
Researchers shed light on skin tone bias in breast cancer imaging
Study finds humidity diminishes daytime cooling gains in urban green spaces
Tennessee RiverLine secures $500,000 Appalachian Regional Commission Grant for river experience planning and design standards
AI tool ‘sees’ cancer gene signatures in biopsy images
Answer ALS releases world's largest ALS patient-based iPSC and bio data repository
2024 Joseph A. Johnson Award Goes to Johns Hopkins University Assistant Professor Danielle Speller
Slow editing of protein blueprints leads to cell death
Industrial air pollution triggers ice formation in clouds, reducing cloud cover and boosting snowfall
Emerging alternatives to reduce animal testing show promise
Presenting Evo – a model for decoding and designing genetic sequences
Global plastic waste set to double by 2050, but new study offers blueprint for significant reductions
Industrial snow: Factories trigger local snowfall by freezing clouds
Backyard birds learn from their new neighbors when moving house
New study in Science finds that just four global policies could eliminate more than 90% of plastic waste and 30% of linked carbon emissions by 2050
Breakthrough in capturing 'hot' CO2 from industrial exhaust
New discovery enables gene therapy for muscular dystrophies, other disorders
Anti-anxiety and hallucination-like effects of psychedelics mediated by distinct neural circuits
[Press-News.org] Neurocognitively-defined subtypes in bipolar disorder: a path to more personalized treatmentsA free webinar from the Brain & Behavior Research Foundation