(Press-News.org) About The Study: Among adults in the intensive care unit who had sepsis or septic shock, the use of prolonged β-lactam antibiotic infusions was associated with a reduced risk of 90-day mortality compared with intermittent infusions. The current evidence presents a high degree of certainty for clinicians to consider prolonged infusions as a standard of care in the management of sepsis and septic shock.
Corresponding Author: To contact the corresponding author, Jason A. Roberts, B.Pharm., Ph.D., email j.roberts@uq.edu.au.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2024.9803)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Media advisory: This study is being presented at the Critical Care Reviews Meeting 2024.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.9803?guestAccessKey=7c5a991a-86dc-4e65-b3a9-ab66a69ab70c&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=061224
END
Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock
JAMA
2024-06-12
ELSE PRESS RELEASES FROM THIS DATE:
Does inflammation in mid-life affect late-life mobility?
2024-06-12
In a recent study published in the Journal of the American Geriatric Society, having high inflammation in mid-life was associated with a clinically meaningful slower gait speed—an indicator of mobility—20 years later.
In the study, which included 4,758 community-dwelling adults, the link between high inflammation and slower late-life gait speed was especially strong for people with sustained high inflammation over the 20-plus years of follow-up. The association was evident even among the healthiest adults who never experienced other common conditions such as obesity, hypertension, ...
Does children’s sensitivity to their parents’ praise affect their future mental health?
2024-06-12
A new study published in Developmental Science found that children who were more positively sensitive to their parents’ praise when they were 3 years old had fewer behavioral and emotional problems when they were 5–7 years old. Children whose behavior did not depend on their mood also had fewer behavioral and emotional problems later.
For the study, which involved 60 children, parents sent in videos of their 3-year-olds brushing their teeth each night across 16 days. Toothbrushing time served as a measure of child behavior. Investigators also noted the amount of ...
How can artificial intelligence be applied to the business needs of the electric power industry?
2024-06-12
A recent study published in IET Generation, Transmission & Distribution explores how artificial intelligence—in particular machine learning techniques—can be leveraged as powerful tools for the electric power and energy industry, and for managing its assets.
By showcasing practical applications and success stories, the study demonstrates the growing acceptance of machine learning as a valuable technology for current and future business needs in the power sector. It also assesses the barriers and difficulties of implementing large-scale ...
Could a novel liver patch help treat and prevent liver disease?
2024-06-12
As described in research published in the Biotechnology Journal, investigators have developed a novel patch that can help liver tissue regenerate.
The patch is a combination of decellularized liver matrix, a liver growth factor, and an anticoagulant. In lab tests with liver cells, the patch helped liver cells regain function after exposure to a toxin.
In rats, patches attached to the liver and gut promoted recovery from liver fibrosis, with notable decreases in scarring and inflammation.
“The decellularized liver matrix–based hepatic patch has demonstrated the ability to ...
Do psychiatric conditions increase the risk of early death in individuals with anorexia nervosa?
2024-06-12
A new study published in the International Journal of Eating Disorders found that mortality rates are high in patients with anorexia nervosa and nearly double in the presence of psychiatric conditions.
For the study, investigators analyzed data on all individuals diagnosed with anorexia nervosa in Denmark in 1977-2018. This included 14,774 patients who were followed for a median time of 9.1 years (and up to 40 years) and were matched 1:10 with age- and sex-matched individuals in the general population.
Individuals with ...
Study demonstrates sustained reduction in child mortality following educational interventions in low-resourced countries
2024-06-12
Pediatric intensive care units (PICUs) in low and middle-income countries see elevated mortality rates, often 10 times higher than those in high-income countries. One leading risk factor is the high incidence of unplanned intubation — a procedure that inserts a tube into the child’s airway — which can lead to complications like hypoxia and ventilator-associated pneumonia. Interventions that improve clinical practices can help reduce child mortality in countries with limited resources.
In a new study published June 12th in Frontiers of Public Health, investigators from Mass ...
Scientists engineer human antibodies that could neutralize black widow toxin
2024-06-12
There are various types of widow spiders, including black, red, and brown varieties in North and South America, the Australian redback spider, and several button spider species that inhabit South Africa. In Europe, Latrodectus tredecimguttatus – the European black widow – inhabits the Mediterranean region, but recently and due to the changing climate, the widows have been expanding their habitat.
Widow spiders’ bites can cause latrodectism, a disease where the spider’s venom, a neurotoxin known as alpha-latrotoxin, attacks the nervous system and causes symptoms like severe ...
How feeling younger impacts dementia caregivers and their loved ones
2024-06-12
The felt age of spousal caregivers is connected to the felt age of their loved ones living with dementia, according to a study from the University of Surrey. This perceived age in people with dementia and their caregivers is related to their own wellbeing, satisfaction with life, and self-confidence.
Felt age is defined as how old someone feels compared to their real age. It's measured by asking people to report whether they feel younger, the same, or older than their actual age. This concept helps understand how people see their own ageing, which can affect their mental and physical health and predict important ...
Towards a new era in flexible piezoelectric sensors for both humans and robots
2024-06-12
Flexible piezoelectric sensors are essential to monitor the motions of both humans and humanoid robots. However, existing designs are either are costly or have limited sensitivity. In a recent study, researchers from Japan tackled these issues by developing a novel piezoelectric composite material made from electrospun polyvinylidene fluoride nanofibers combined with dopamine. Sensors made from this material showed significant performance and stability improvements at a low cost, promising advancements ...
New study suggests kidney function is associated with tooth loss in postmenopausal women
2024-06-12
CLEVELAND, Ohio (June 12, 2024)—Kidneys play a critical role in overall health by removing waste products from the blood. When they fail to sufficiently filter out foreign elements, several serious, lifethreatening, medical conditions can result. A new study suggests that chronic kidney disease may also be linked with tooth loss. Results of the survey are published online today in Menopause, the journal of The Menopause Society.
A woman’s glomerular filtration rate shows how well her kidneys are functioning. ...
LAST 30 PRESS RELEASES:
Less intensive works best for agricultural soil
Arctic rivers project receives “national champion” designation from frontiers foundation
Computational biology paves the way for new ALS tests
Study offers new hope for babies born with opioid withdrawal syndrome
UT, Volkswagen Group of America celebrate research partnership
New Medicare program could dramatically improve affordability for cancer drugs – if patients enroll
Are ‘zombie’ skin cells harmful or helpful? The answer may be in their shapes
University of Cincinnati Cancer Center presents research at AACR 2025
Head and neck, breast, lung and survivorship studies headline Dana-Farber research at AACR Annual Meeting 2025
AACR: Researchers share promising results from MD Anderson clinical trials
New research explains why our waistlines expand in middle age
Advancements in muon detection: Taishan Antineutrino Observatory's innovative top veto tracker
Chips off the old block
Microvascular decompression combined with nerve combing for atypical trigeminal neuralgia
Cutting the complexity from digital carpentry
Lung immune cell type “quietly” controls inflammation in COVID-19
Fiscal impact of expanded Medicare coverage for GLP-1 receptor agonists to treat obesity
State and sociodemographic trends in US cigarette smoking with future projections
Young adults drive historic decline in smoking
NFCR congratulates Dr. Robert C. Bast, Jr. on receiving the AACR-Daniel D. Von Hoff Award for Outstanding Contributions to Education and Training in Cancer Research
Chimpanzee stem cells offer new insights into early embryonic development
This injected protein-like polymer helps tissues heal after a heart attack
FlexTech inaugural issue launches, pioneering interdisciplinary innovation in flexible technology
In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity
Methyl eugenol: potential to inhibit oxidative stress, address related diseases, and its toxicological effects
A vascularized multilayer chip reveals shear stress-induced angiogenesis in diverse fluid conditions
AI helps unravel a cause of Alzheimer's disease and identify a therapeutic candidate
Coalition of Autism Scientists critiques US Department of Health and Human Services Autism Research Initiative
Structure dictates effectiveness, safety in nanomedicine
Mission accomplished for the “T2T” Hong Kong Bauhinia Genome Project
[Press-News.org] Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shockJAMA