(Press-News.org) About The Study: In this population of adults with overweight or obesity, use of tirzepatide was associated with significantly greater weight loss than semaglutide. Future study is needed to understand differences in other important outcomes.
Corresponding Author: To contact the corresponding author, Nicholas L. Stucky, M.D., email nicholass@truveta.com.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamainternmed.2024.2525)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.2525?guestAccessKey=1d98a3bc-0a11-444c-a21a-2b875588f3f0&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=070824
END
Semaglutide vs tirzepatide for weight loss in adults with overweight or obesity
JAMA Internal Medicine
2024-07-08
ELSE PRESS RELEASES FROM THIS DATE:
AJPH study shows that permit to purchase laws are a promising avenue to reduce suicides in young adults
2024-07-08
In 2020, suicide ranked as the third leading cause of death for adults aged 18 to 20 years in the United States. Firearms were implicated in approximately half of these cases, and by 2017, they had surpassed motor vehicles as the leading cause of death in this age group. While ongoing debates on gun violence and mental health have increased public support for restricted firearm access, not much is known about the impact of gun control policies on young adults.
To fill this knowledge gap, a recent study published in the August issue of the American Journal of Public Health on July 03, ...
Companies that mitigate climate change reduce their cost of capital
2024-07-08
Fukuoka, Japan —The climate crisis is hitting home with more frequent extreme weather events. Companies, particularly those in high-emission industries, are major contributors to global carbon emissions, therefore making them key players in the fight against climate change. Recognizing this responsibility, many businesses are now taking proactive measures to reduce their carbon footprint, by reducing carbon emissions and transparently sharing their environmental strategies and data.
The Task Force on Climate-Related Financial Disclosures ...
Case Western Reserve University receives $1.5M grant from Foundation Fighting Blindness to test possible new treatment for inherited retinal disease
2024-07-08
CLEVELAND—There’s only one U.S. Food and Drug Administration-approved therapy for an inherited retinal disease, and dozens of retinitis pigmentosa (RP) genes for which no therapy is available.
With a new three-year, $1.5 million grant from the Foundation Fighting Blindness, Shigemi Matsuyama, an associate professor of ophthalmology and visual sciences at the Case Western Reserve University School of Medicine, will test a possible breakthrough drug that can be taken by mouth—one that may address many RP disease manifestations, regardless of the underlying genetic mutation.
“We believe it can serve as the basis of an oral medicine to prevent blindness in RP ...
How to stop cancer cachexia? Start at the top
2024-07-08
Cancer is insidious. Throughout tumor progression, the disease hijacks otherwise healthy biological processes—like the body’s immune response—to grow and spread. When tumors elevate levels of an immune system molecule called Interleukin-6 (IL-6), it can cause severe brain dysfunction. In about 50%-80% of cancer patients, this leads to a lethal wasting disease called cachexia. “It’s a very severe syndrome,” says Cold Spring Harbor Laboratory (CSHL) Professor Bo Li.
“Most people with cancer die of cachexia instead of cancer. And once the patient enters this stage, there’s ...
Pulsed field ablation procedures found safe and effective for atrial fibrillation patients
2024-07-08
Pulsed field ablation (PFA) is safe for treating patients with common types of atrial fibrillation (AF), according to the largest study of its kind on this new technology, led by the Icahn School of Medicine at Mount Sinai.
The “MANIFEST-17K” international study is the first to show important safety outcomes in a large patient population, including no significant risk of esophageal damage, with PFA. PFA is the latest ablation modality approved by the Food and Drug Administration that can be used to restore a regular heartbeat. The findings, published July 8 in Nature Medicine, could lead to more frequent use of PFA instead of conventional therapies to manage AF patients.
“MANIEFST-17K ...
Why some abusive bosses get a pass from their employees
2024-07-08
COLUMBUS, Ohio – Why do employees sometimes accept working for an abusive boss?
A new study suggests that when a leader is seen as a high performer, employees are more likely to label abuse as just “tough love.”
Results showed that workers were less likely to show hostility to abusive bosses when the leader’s performance was high, and employees were even likely to think their career could be boosted by a successful – if abusive – boss.
The findings suggest that employees may be reluctant to call a successful boss abusive – ...
UNC researchers identify potential treatment for Angelman syndrome
2024-07-08
CHAPEL HILL, N.C. – Angelman syndrome is a rare genetic disorder caused by mutations in the maternally-inherited UBE3A gene and characterized by poor muscle control, limited speech, epilepsy, and intellectual disabilities. Though there isn't a cure for the condition, new research at the UNC School of Medicine is setting the stage for one.
Ben Philpot, PhD, the Kenan Distinguished Professor of Cell Biology and Physiology at the UNC School of Medicine and associate director of the UNC Neuroscience Center, and his lab have identified a small molecule that could be safe, non-invasively delivered, and capable of ...
Study: Weaker ocean circulation could enhance CO2 buildup in the atmosphere
2024-07-08
As climate change advances, the ocean’s overturning circulation is predicted to weaken substantially. With such a slowdown, scientists estimate the ocean will pull down less carbon dioxide from the atmosphere. However, a slower circulation should also dredge up less carbon from the deep ocean that would otherwise be released back into the atmosphere. On balance, the ocean should maintain its role in reducing carbon emissions from the atmosphere, if at a slower pace.
However, a new study by an MIT researcher finds that scientists may have to rethink the relationship between the ocean’s circulation and its ...
Brain size riddle solved as humans exceed evolution trend
2024-07-08
The largest animals do not have proportionally bigger brains - with humans bucking this trend - a new study published in Nature Ecology and Evolution has revealed.
Researchers at the University of Reading and Durham University collected an enormous dataset of brain and body sizes from around 1,500 species to clarify centuries of controversy surrounding brain size evolution.
Bigger brains relative to body size are linked to intelligence, sociality, and behavioural complexity – with humans having evolved exceptionally large brains. The new research, published today (Monday, 8 July), reveals the largest animals do not have proportionally bigger brains, ...
GeneMAP discovery platform will help define functions for ‘orphan’ metabolic proteins
2024-07-08
A multidisciplinary research team has developed a discovery platform to probe the function of genes involved in metabolism — the sum of all life-sustaining chemical reactions.
The investigators used the new platform, called GeneMAP (Gene-Metabolite Association Prediction), to identify a gene necessary for mitochondrial choline transport. The resource and derived findings were published July 8 in the journal Nature Genetics.
“We sought to gain insight into a fundamental question: ‘How does genetic variation determine our “chemical individuality” — the inherited differences that make us biochemically unique?” said Eric Gamazon, ...
LAST 30 PRESS RELEASES:
Fathers’ microplastic exposure tied to their children’s metabolic problems
Research validates laboratory model for studying high-grade serous ovarian cancer
SIR 2026 delivers transformative breakthroughs in minimally invasive medicine to improve patient care
Stem Cell Reports most downloaded papers of 2025 highlight the breadth and impact of stem cell research
Oxford-led study estimates NHS spends around 3% of its primary and secondary care budget on the health impacts of heat and cold in England
A researcher’s long quest leads to a smart composite breakthrough
Urban wild bees act as “microbial sensors” of city health.
New study finds where you live affects recovery after a hip fracture
Forecasting the impact of fully automated vehicle adoption on US road traffic injuries
Alcohol-related hospitalizations from 2016 to 2022
Semaglutide and hospitalizations in patients with obesity and established cardiovascular disease
Researchers ‘listen in’ to embryo-mother interactions during implantation using a culture system replicating the womb lining
How changing your diet could help save the world
How to make AI truly scalable and reliable for real-time traffic assignment?
Beyond fragmented markets: A new framework for efficient and stable ride-pooling
Can shape priors make road perception more reliable for autonomous driving?
AI tracks nearly 100 years of aging research, revealing key trends and gaps
Innovative techniques enable Italy’s first imaging of individual trapped atoms
KIER successfully develops Korea-made “calibration thermoelectric module” for measuring thermoelectric device performance
Diversifying US Midwest farming for stability and resilience
Emphasizing immigrants’ deservingness shifts attitudes
Japanese eels, climate change, and river temperature
Pusan National University researchers discover faster, smarter heat treatment for lightweight magnesium metals
China’s 2024 Gastroenterology Report: marked progress in endoscopy quality and disease management
Pusan National University researchers uncover scalable method for ultrahigh-resolution quantum dot displays
Researchers use robotics to find potential new antibiotic among hundreds of metal complexes
Gut bacteria changes at the earliest stages of inflammatory bowel disease
Scientists develop new way to “listen in” on the brain’s hidden language
Brain research: “Pulse generators” grow and shrink as memories are formed
For teens, any cannabis use may have impact on emotional health, academic performance
[Press-News.org] Semaglutide vs tirzepatide for weight loss in adults with overweight or obesityJAMA Internal Medicine





