(Press-News.org) OAK BROOK, Ill. – Analysis of CT scans in people who undergo imaging for health screening can identify individuals at risk of type 2 diabetes, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA). Researchers said the findings underscore CT’s value in opportunistic imaging—the use of information from routine imaging examinations to learn more about a patient’s overall health.
For the new study, researchers evaluated the ability of automated CT-derived markers to predict diabetes and associated conditions.
“Given the significant burden of diabetes and its complications, we aimed to explore whether automated and precise imaging analyses could enhance early detection and risk stratification beyond conventional methods,” said study senior author Seungho Ryu, M.D., Ph.D., from the Kangbuk Samsung Hospital at Sungkyunkwan University School of Medicine in Seoul, South Korea.
The study group included 32,166 adults ages 25 years or older who underwent health screening with 18F-fluorodeoxyglucose (18F-FDG) PET/CT.
Dr. Ryu and colleagues used clinically validated deep learning algorithms to analyze the CT images. The algorithms enabled 3D segmentation and quantification of various body components such as visceral fat, subcutaneous fat, muscle mass, liver density and aortic calcium.
Diabetes prevalence was 6% at baseline and incidence was 9% during the 7.3-year median follow-up.
Automated multiorgan CT analysis identified individuals at high risk of diabetes and associated conditions. The index of visceral fat—the belly fat under the muscles and around the organs of the abdomen—showed the highest predictive performance for diabetes. Combining visceral fat, muscle area, liver fat fraction and aortic calcification improved predictive performance. CT-derived markers also identified ultrasound-diagnosed fatty liver, coronary artery calcium scores of more than 100, osteoporosis and age-related muscle loss called sarcopenia.
These markers outperformed traditional risk factors in predicting type 2 diabetes.
“The results are encouraging as they demonstrate the potential of expanding the role of CT imaging from conventional disease diagnosis to opportunistic proactive screening,” Dr. Ryu said. “This automated CT analysis improves risk prediction and early intervention strategies for diabetes and related health issues.”
In the clinical setting, these CT-derived markers have the potential to improve the conventional approach to diabetes screening and risk assessment, Dr. Ryu noted.
“By integrating these advanced imaging techniques into opportunistic health screenings, clinicians can identify individuals at high risk for diabetes and its complications more accurately and earlier than the current approach,” he said. “This could lead to more personalized and timely interventions, ultimately improving patient outcomes.”
###
“Automated Comprehensive CT Assessment of the Risk of Diabetes and Associated Cardiometabolic Conditions.” Collaborating with Dr. Ryu were Yoosoo Chang, M.D., Ph.D., Soon Ho Yoon, M.D., Ph.D., Ria Kwon, Ph.D., Jeonggyu Kang, M.D., Young Hwan Kim, M.D., Ph.D., Jong-Min Kim, Ph.D., Han-Jae Chung, Ph.Dc., JunHyeok Choi, Ph.Dc., Hyun-Suk Jung, MD, Ph.D., Ga-Young Lim, Ph.D., Jiin Ahn, M.S.P.H., Sarah H. Wild, M.B., B.Chir., Ph.D., and Christopher D. Byrne, M.B.B.Ch., Ph.D.
Radiology is edited by Linda Moy, M.D., New York University, New York, N.Y., and owned and published by the Radiological Society of North America, Inc. (https://pubs.rsna.org/journal/radiology)
RSNA is an association of radiologists, radiation oncologists, medical physicists and related scientists promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Illinois. (RSNA.org)
For patient-friendly information on CT, visit RadiologyInfo.org.
END
OAK BROOK, Ill. – A deep learning model performs at the level of an abdominal radiologist in the detection of clinically significant prostate cancer on MRI, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA). The researchers hope the model can be used as an adjunct to radiologists to improve prostate cancer detection.
Prostate cancer is the second most common cancer in men worldwide. Radiologists typically use a technique that combines different MRI sequences (called multiparametric MRI) to diagnose clinically significant prostate cancer. ...
CHICAGO – Nearly 100 wildfires are currently raging throughout the country, burning more than 2 million acres. The rising frequency of these fires poses a special concern for anesthesiologists – the potential for increased rates of adverse outcomes from anesthesia and surgery among patients exposed to wildfire smoke, according to a special article in the Online First edition of Anesthesiology, the peer-reviewed journal of the American Society of Anesthesiologists (ASA).
"Wildfire smoke causes inflammation and is known to worsen heart and lung disease and pregnancy outcomes," said senior author Vijay Krishnamoorthy, M.D., M.P.H., Ph. D., chief of the Critical Care ...
A new study by an international team of collaborators led by researchers at the University of Vienna, and in collaboration with the Dom Museum Wien, aimed to address the questions of whether art exhibitions can make us more empathic or even change our attitudes and behaviors? The researchers were able to show that, indeed, looking through the exhibition reduced xenophobia and increased acceptance of immigration. Even more, by employing a new cellphone-based experience sampling method, they could track how long ...
Some believe the future of fusion in the U.S. lies in compact, spherical fusion vessels. A smaller tokamak, it is thought, could offer a more economical fusion option. The trick is squeezing everything into a small space. New research suggests eliminating one major component used to heat the plasma, freeing up much-needed space.
Scientists at the U.S. Department of Energy’s (DOE) Princeton Plasma Physics Laboratory (PPPL), the private company Tokamak Energy and Kyushu University in Japan have proposed a design for a compact, spherical fusion pilot plant ...
One popular strategy to motivate people to get vaccinated is the nudge—a message designed to take advantage of human tendencies to conform to social norms, seek to protect loved ones or community, and to prefer treatments with high efficacy rates. Jiseon Chang and colleagues sought to assess the efficacy of such nudges in real world contexts during the COVID-19 pandemic. The authors paid for ads to appear on Facebook between October 2021 and January 2022, reaching almost 15 million users in Brazil, Russia, South Africa, Taiwan, ...
More than 1 in 4 people age 50 and older helps take care of at least one family member or friend who has a health problem or disability, a new poll finds.
And among those caregivers, the new results from the University of Michigan National Poll on Healthy Aging reveal a lot about who they are and who they’re caring for.
In all, 30% of all people in their 50s and early 60s provide care to at least one person with a health issue or disability, compared with 23% of people over 65. And 1 in 10 caregivers in their 50s and early 60s are juggling taking care of three or more people.
In ...
To Predict Tax Revenue, Look at Corporate Earnings
States can make more accurate budget forecasts and avoid midyear cuts if they include growth in corporate earnings
AUSTIN, Texas -- In the complex task of building a state budget, much rides on the accuracy of its fiscal crystal ball: its forecast of how much tax revenue will come in to fund services during the year ahead. Forecasting errors have increased since 2001 due to revenue volatility, such as wider swings in personal income and consumer spending.
New research from Texas ...
MINNEAPOLIS / ST. PAUL (08/06/2024) — Researchers at the University of Minnesota, have developed a new visual diagnostic technique that can be used to advance early detection for neurodegenerative diseases like Parkinson's disease and similar diseases that affect animals, including Chronic Wasting Disease in deer.
The research is published in npj Biosensing, a peer-reviewed scientific journal published by Nature.
Named Cap-QuIC (Capillary-enhanced Quaking-Induced Conversion), researchers will now be able to distinguish infected samples with the naked eye, which makes testing ...
People with higher levels of metals found in their blood and urine may be more likely to be diagnosed with — and die from — amyotrophic lateral sclerosis, or ALS, a University of Michigan-led study suggests.
Researchers have known that ALS, a rare but fatal neurodegenerative condition, is influenced by genetic and environmental factors, including exposure to pesticides and metals.
This latest study examined the levels of metals in the blood and urine of people with and without ALS, finding that exposure to individual and mixtures of metals is associated with a greater risk for ALS and shorter survival.
The ...
PULLMAN, Wash. – It may be possible to turn anxiety into a superpower in some scenarios, recent research with entrepreneurs indicates.
A Washington State University-led study found that if entrepreneurs preparing to make a funding pitch connected their pitch anxiety to their passion for their venture, judges ranked their performance higher. Perhaps even more importantly, the judges were also more likely to recommend them for funding.
This emotion reframing involved the entrepreneurs recognizing that they were feeling anxious partly because the project means so much to them. Entrepreneurs who tried other strategies ...
