PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Fierce names Insilico Medicine as one of its Fierce 50 Honorees of 2024

2024-10-01
(Press-News.org) Cambridge, MA, Sept. 26, 2024 –Insilico Medicine, a clinical-stage generative AI-driven drug discovery company, announced today that Fierce Life Sciences and Fierce Healthcare have named Insilico Medicine as one of 2024’s Fierce 50 honorees. The Fierce 50 showcases 50 individuals and companies driving advancements in medicine, fostering innovation and shaping the future of biopharma and healthcare.

“The annual Fierce 50 special report highlights individuals and companies that are driving progress in the pharmaceutical, healthcare and biotechnology industries,” said Ayla Ellison, Editor-in-Chief of Fierce Life Sciences and Healthcare. “These 50 outstanding organizations and people demonstrate excellence in their fields, and their commitment to innovation, equity and improving lives is truly commendable. Congratulations to this year’s honorees.”

Founded in 2014, Insilico first described the concept of using generative AI for the design of novel molecules in a peer-reviewed journal, which laid the foundation for the commercially available Pharma.AI platform. Since then, Insilico keeps integrating technical breakthroughs into the Pharma.AI platform, which is currently a generative AI-powered solution spanning across biology, chemistry and clinical development. Powered by Pharma.AI, Insilico has nominated 20 preclinical candidates in its comprehensive portfolio of over 30 assets of which 9 molecules have received IND approval.

In early 2024, Insilico published a Nature Biotechnology paper presenting the entire R&D journey from AI algorithms to Phase II clinical trials of ISM001_055, the company’s lead asset,  with an AI-discovered target and AI-designed structure. Following that, Insilico has recently announced positive preliminary results from a Phase IIa trial (NCT05938920), where ISM001_055 showed favorable safety and tolerability across all dose levels, as well as dose-dependent response in forced vital capacity (FVC), after only 12 weeks of dosage.

“We are incredibly honored to be named one of the 2024 Fierce 50, following our previous recognition as a Fierce 15 honoree by Fierce Medtech in 2019,” Said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. “This prestigious recognition is a testament to Insilico's relentless innovation in AI-driven drug research and development. It further inspires our team to leverage advanced generative AI technology and robotics to accelerate the creation of innovative therapies for patients with unmet medical needs worldwide.”

The Fierce 50 is a constellation of the most brilliant visionaries and trailblazers, handpicked by the discerning editors of Fierce Biotech, Fierce Pharma and Fierce Healthcare. These individuals and companies are a driving force in healthcare delivery, drug development, research, and more. The Fierce 50 honorees will be honored live at an evening gala at the Lighthouse at Pier Sixty One in New York on December 5th.  For more information visit https://fierce50.fiercelifesciences.com/.

About Insilico Medicine

Insilico Medicine, a global clinical-stage biotechnology company powered by generative AI, connects biology, chemistry, and clinical trial analysis using next-generation AI systems. The company has developed AI platforms that utilize deep generative models, reinforcement learning, transformers, and other modern machine learning techniques to assist novel target discovery and the generation of novel molecular structures. Insilico Medicine is developing breakthrough solutions to discover and develop innovative drugs for cancer, fibrosis, immunity, central nervous system diseases, infectious diseases, autoimmune diseases, and aging-related diseases. www.insilico.com

 

END


ELSE PRESS RELEASES FROM THIS DATE:

Cleveland Clinic researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

Cleveland Clinic researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy
2024-10-01
A Cleveland Clinic-led research collaboration between Timothy Chan, MD, PhD, Chair of Cleveland Clinic’s Global Center for Immunotherapy, and Bristol Myers Squibb has published the most comprehensive overview to date of how the immune system reshapes tumor architecture in response to immune checkpoint therapy.  The eight-year study, published in Nature Medicine, outlines how cancer immunotherapy induces tumor recognition through neoantigens to reshape the tumor ecosystem. Neoantigens are small peptides produced when cancer cells mutate and are a primary marker for the immune system to recognize cancer cells as different ...

Pioneering quantum computer research continues in Baden-Württemberg

2024-10-01
Utilizing the potential of quantum computers and achieving a real advantage for practical applications — this goal is being pursued worldwide. In Baden-Württemberg, the Competence Center Quantum Computing Baden-Württemberg (KQCBW) has dedicated itself to this goal over the past four years. Great progress has been made in various areas of quantum computing in successful joint projects. The success of the KQCBW is now to be continued and the unique quantum computing ecosystem in the state further expanded. The KQCBW will be continued in a ten-month transfer project ...

Discovery of orbital angular momentum monopoles enables orbital electronics with chiral materials

Discovery of orbital angular momentum monopoles enables orbital electronics with chiral materials
2024-10-01
In traditional electronics, information is transferred using the charge of electrons. However, future technologies may rely on a different property of electrons—their intrinsic angular momentum. Historically, the focus has been on electron spin, a form of build-in angular momentum that creates a magnetic moment, as the leading candidate for next-generation devices. Now, researchers are exploring the potential of orbitronics, a field that utilizes the angular momentum of electrons generated as they orbit the atomic nucleus. Orbitronics holds great promise ...

New mouse models offer valuable window into COVID-19 infection

New mouse models offer valuable window into COVID-19 infection
2024-10-01
LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19.  According to their new study in eBioMedicine, these mouse models are important for COVID-19 research because their cells were engineered to include two important human molecules that are involved in SARS-CoV-2 infection of human cells—and these humanized mice were generated on two different immunologic backgrounds. ...

Antibodies in breast milk provide protection against common GI virus

2024-10-01
A study led by researchers at the University of Rochester Medical Center found that breast milk provides protection against rotavirus, a common gastrointestinal disease that causes diarrhea, vomiting and fever in infants. Babies whose mothers had high levels of specific antibodies in their breast milk were able to fend off the infection for a longer period than infants whose mothers had lower levels. The findings are expected to drive future research to improve infant health through optimized breastfeeding practices. Published in the Journal of Clinical Investigation and funded by the Bill and Melinda Gates Foundation, the study also ...

University of Cincinnati professor named MacArthur fellow

2024-10-01
When the phone rang on a September afternoon, University of Cincinnati's Shailaja Paik, PhD, tired from a full day of meetings and teaching, did not expect to hear news that would leave her “ears numb.” “I had been named a (MacArthur) fellow, and I wasn’t sure I was hearing correctly, but I tried to keep my cool,” she remembers, chuckling. “I thought, ‘Is this right? I’m going to ask her to repeat herself.’ “I was ecstatic.” The MacArthur Fellows Program, also ...

Research provides new insights into role of mechanical forces in gene expression

Research provides new insights into role of mechanical forces in gene expression
2024-10-01
The genome inside each of our cells is modelled by tension and torsion — due in part to the activity of proteins that compact, loop, wrap and untwist DNA — but scientists know little about how those forces affect the transcription of genes. “There are a lot of mechanical forces at play all the time that we never consider, we have very little knowledge of, and they’re not talked about in textbooks,” said Laura Finzi, the Dr. Waenard L. Miller, Jr. ’69 and Sheila M. Miller Endowed Chair in Medical Biophysics at Clemson University. Transcription is the process by which a cell makes an RNA copy of a segment of DNA. One ...

HSE scientists have developed a new model of electric double layer

2024-10-01
This new model accounts for a wide range of ion-electrode interactions and predicts a device's ability to store electric charge. The model's theoretical predictions align with the experimental results. Data on the behaviour of the electric double layer (EDL) can aid in the development of more efficient supercapacitors for portable electronics and electric vehicles. The study has been published in ChemPhysChem. Many devices store energy for future use, with batteries being among the most well-known examples. They can consistently release energy, maintaining steady power output regardless of existing conditions or load, until fully ...

UK ParkRun participants report improved life satisfaction six months later

UK ParkRun participants report improved life satisfaction six months later
2024-10-01
UK ParkRun participants report improved life satisfaction six months later, with most benefit for the least active people, and an estimated value between £16.70 and £98.50 for every £1 of running costs.  #### Article URL: https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0003580 Article Title: The impact of parkrun on life satisfaction and its cost-effectiveness: A six-month study of parkrunners in the United Kingdom Author Countries: United Kingdom Funding: This study was funded by Sheffield Hallam University (SJH and AB) and by The University of Sheffield (HQ). The funders had no role in study design, data collection and analysis, ...

‘Who’s a good boy?’ Humans use dog-specific voices for better canine comprehension

‘Who’s a good boy?’ Humans use dog-specific voices for better canine comprehension
2024-10-01
The voice people use to address their dogs isn’t just because of their big puppy eyes. Humans slow their own speech when talking to their dogs, and this slower tempo matches their pets’ receptive abilities, allowing the dogs to better understand their commands, according to a study published October 1st in the open-access journal PLOS Biology by Eloïse Déaux of the University of Geneva in Switzerland and colleagues. Dogs respond to human speech, even though they themselves cannot produce human sounds. To better understand how people ...

LAST 30 PRESS RELEASES:

Singles differ in personality traits and life satisfaction compared to partnered people

President Biden signs bipartisan HEARTS Act into law

Advanced DNA storage: Cheng Zhang and Long Qian’s team introduce epi-bit method in Nature

New hope for male infertility: PKU researchers discover key mechanism in Klinefelter syndrome

Room-temperature non-volatile optical manipulation of polar order in a charge density wave

Coupled decline in ocean pH and carbonate saturation during the Palaeocene–Eocene Thermal Maximum

Unlocking the Future of Superconductors in non-van-der Waals 2D Polymers

Starlight to sight: Breakthrough in short-wave infrared detection

Land use changes and China’s carbon sequestration potential

PKU scientists reveals phenological divergence between plants and animals under climate change

Aerobic exercise and weight loss in adults

Persistent short sleep duration from pregnancy to 2 to 7 years after delivery and metabolic health

Kidney function decline after COVID-19 infection

Investigation uncovers poor quality of dental coverage under Medicare Advantage

Cooking sulfur-containing vegetables can promote the formation of trans-fatty acids

How do monkeys recognize snakes so fast?

Revolutionizing stent surgery for cardiovascular diseases with laser patterning technology

Fish-friendly dentistry: New method makes oral research non-lethal

Call for papers: 14th Asia-Pacific Conference on Transportation and the Environment (APTE 2025)

A novel disturbance rejection optimal guidance method for enhancing precision landing performance of reusable rockets

New scan method unveils lung function secrets

Searching for hidden medieval stories from the island of the Sagas

Breakthrough study reveals bumetanide treatment restores early social communication in fragile X syndrome mouse model

Neuroscience leader reveals oxytocin's crucial role beyond the 'love hormone' label

Twelve questions to ask your doctor for better brain health in the new year

Microelectronics Science Research Centers to lead charge on next-generation designs and prototypes

Study identifies genetic cause for yellow nail syndrome

New drug to prevent migraine may start working right away

Good news for people with MS: COVID-19 infection not tied to worsening symptoms

Department of Energy announces $179 million for Microelectronics Science Research Centers

[Press-News.org] Fierce names Insilico Medicine as one of its Fierce 50 Honorees of 2024