Alzheimer disease as a clinical-biological construct— an international working group recommendation

JAMA Neurology

2024-11-01

(Press-News.org) About The Study: This article discusses a recent revision of the Alzheimer Association criteria to define Alzheimer disease (AD) as a purely biological entity, which raises concerns that if diagnosis of AD can be reduced to the sole presence of AD core 1 biomarkers, major uncertainty and variability in the clinical prognosis of patients diagnosed with AD may be introduced.

Corresponding Author: To contact the corresponding author, Bruno Dubois, MD, MSc, email bruno.dubois@aphp.fr.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaneurol.2024.3770)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory: This study is being presented at the 17th Clinical Trials on Alzheimer’s Disease conference.

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Alzheimer disease as a clinical-biological construct— an international working group recommendation

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