(Press-News.org) Original Research
Background and Goal: This study explored how chest X-ray results influence antibiotic initiation by general practitioners in France when managing patients with suspected pneumonia.
Study Approach: A prospective cross-sectional study was conducted with adult patients with suspected pneumonia who received chest X-rays as part of their evaluation. To analyze factors associated with antibiotic initiation, patients’ characteristics were compared at inclusion and at 28 days between patients with positive chest X-rays (indicating pneumonia) and patients with negative chest X-ray results.
Main Results: The sample included 259 adult patients. The median age was 58 years, 120 (46.3%) were male, 249 (96.1%) had not received antibiotics prior to inclusion, and 69 (26.7%) had at least one risk factor for pneumococcal disease.
Most of the general practitioners who included patients were women (55.2 %; n = 153), with a median age of 39 years. 76.1% (n = 210) were general practitioner trainers.
55.6% of patients (144 out of 259) had positive chest X-ray results.
Patients with positive chest X-ray results had higher body temperature, faster heart rate, faster breathing rate, more difficulty breathing, and more frequent unilateral chest pain than patients with negative X-ray results, and their symptoms lasted for a longer time.
99.3% of patients with positive chest X-ray results received antibiotics. Despite fewer symptoms and negative chest X-ray results, a significant portion (68.75%) of patients with negative chest X-ray results were prescribed antibiotics (79/115 patients).
Why It Matters: The findings of this study show that many general practitioners prescribe antibiotics for suspected community-acquired pneumonia even when chest X-ray results are negative, highlighting a gap between guidelines and actual practice.
Relationship Between Chest Radiography Results and Antibiotic Initiation in Community-Acquired Pneumonia Management by General Practitioners
Juliette Pinot, MD, et al
Université Paris Cité and Université Sorbonne Paris Nord, INSERM, IAME, Paris, France
Université Paris Cité, Department of General Practice, Paris, France
PERMANENT LINK
Visual Abstract:
END
Antibiotics initiated for suspected community-acquired pneumonia even when chest radiography results are negative
Relationship between chest radiography results and antibiotic initiation in community-acquired pneumonia management by general practitioners
2024-11-25
[Attachments] See images for this press release:
ELSE PRESS RELEASES FROM THIS DATE:
COVID-19 stay-at-home order increased reporting of food, housing, and other health-related social needs in Oregon
2024-11-25
Background and Goal: Efforts to address the health-related social needs (HRSN) of Medicare and Medicaid beneficiaries, such as housing and food, during the COVID-19 pandemic were insufficient. This research examined HRSN data from the Accountable Health Communities (AHC) study collected in Oregon to understand changes in HRSN for Medicare and Medicaid beneficiaries at the onset and during the first two years of the pandemic.
Study Approach: The study sample included 21,522 Medicare and Medicaid beneficiaries screened for overall health-related social needs between ...
UW-led research links wildfire smoke exposure with increased dementia risk
2024-11-25
As Baby Boomers hit retirement, about 1 in 6 Americans is now over the age of 65. The number of Americans living with dementia is projected to skyrocket — but the proportion of older Americans who develop dementia has actually decreased. The exact reason why is uncertain, but various lifestyle and environmental factors can influence a person’s risk of cognitive decline.
One recently discovered risk is air pollution. Studies have linked exposure to a type of air pollution called fine particulate matter, or PM2.5, with an increased risk of developing dementia, and researchers suspect ...
Most U.S. adults surveyed trust store-bought turkey is free of contaminants, despite research finding fecal bacteria in ground turkey
2024-11-25
WASHINGTON, D.C. ؚ— More than six out of 10 U.S. adults who took part in a Physicians Committee for Responsible Medicine/Morning Consult survey last week say they wouldn’t eat turkey contaminated with feces, yet consumer research has shown more than half of store-bought packages of ground turkey tested positive for it.
The poll included 2,183 adults interviewed Nov. 18 to Nov. 20, 82% of whom said they plan to eat turkey for Thanksgiving this year. Of those, 87% said they trust it’ll be free from contaminants, but 65% said if they knew it was contaminated with fecal bacteria, they’d be unlikely to eat it.
In research conducted by Consumer Reports in ...
New therapy from UI Health offers FDA-approved treatment option for brittle type 1 diabetes
2024-11-25
A new therapy for brittle type 1 diabetes, the only treatment currently approved by the U.S. Food and Drug Administration, is available exclusively at UI Health in Chicago.
Pancreatic islet cell therapy is a treatment approved by the FDA only for adults with type 1 diabetes who struggle to control their blood sugar levels due to frequent episodes of severe low blood sugar and hypoglycemia unawareness, a condition that occurs when patients can’t detect that their blood sugar is dropping. This new therapy, called Lantidra, is derived from a deceased donor pancreas. To regulate blood glucose, the drug is infused into the patient’s liver where insulin is produced. ...
Alzheimer's: A new strategy to prevent neurodegeneration
2024-11-25
A future treatment for Alzheimer disease may involve a nasal spray. Researchers at Università Cattolica and Fondazione Policlinico Universitario A. Gemelli IRCCS have discovered that by inhibiting the brain enzyme S-acyltransferase (zDHHC) through a nasal-spray drug, they can counteract the cognitive decline and brain damage typical of the disease. The study has been led by Professor Claudio Grassi, Director of the Neuroscience Department, and Professor Salvatore Fusco, with the collaboration of the University of Catania.
The researchers observed that the post-mortem brains of Alzheimer patients contained an excess of S-acyltransferase, ...
A clue to what lies beneath the bland surfaces of Uranus and Neptune
2024-11-25
Diamond rain? Super-ionic water?
These are just two proposals that planetary scientists have come up with for what lies beneath the thick, bluish, hydrogen-and-helium atmospheres of Uranus and Neptune, our solar system's unique, but superficially bland, ice giants.
A planetary scientist at the University of California, Berkeley, now proposes an alternative theory — that the interiors of both these planets are layered, and that the two layers, like oil and water, don't mix. That configuration neatly explains the planets' unusual magnetic fields and implies ...
Researchers uncover what makes large numbers of “squishy” grains start flowing
2024-11-25
Researchers Samuel Poincloux (currently at Aoyama Gakuin University) and Kazumasa A. Takeuchi of the University of Tokyo have clarified the conditions under which large numbers of “squishy” grains, which can change their shape in response to external forces, transition from acting like a solid to acting like a liquid. Similar transitions occur in many biological processes, including the development of an embryo: cells are “squishy” biological “grains” that form solid tissues and sometimes flow to form different organs. Thus, the experimental and theoretical framework elaborated here will help separate the ...
Scientists uncover new mechanism in bacterial DNA enzyme opening pathways for antibiotic development
2024-11-25
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target.
This enzyme, present in bacteria but absent in humans, plays a crucial role in supercoiling DNA, a necessary process for bacterial survival.
Using high-resolution cryo-electron microscopy the researchers reveal unprecedented detail of gyrase’s action on DNA, potentially opening doors for new antibiotic therapies against resistant bacteria.
The research is published in Proceedings of the ...
New study reveals the explosive secret of the squirting cucumber
2024-11-25
UNDER EMBARGO UNTIL 20:00 GMT / 15:00 ET MONDAY 25 NOVEMBER 2024
New study reveals the explosive secret of the squirting cucumber
IMAGES AND VIDEO AVAILABLE – SEE NOTES SECTION BELOW
A team led by the University of Oxford has solved a mystery that has intrigued scientists for centuries: how does the squirting cucumber squirt? The findings, achieved through a combination of experiments, high-speed videography, image analysis, and advanced mathematical modelling, have been published today (25 November) in The Proceedings of the National Academy of Sciences (PNAS).
The squirting cucumber (Ecballium elaterium, from the Greek ‘ekballein,’ meaning to throw out) is named for ...
Vanderbilt authors find evidence that the hunger hormone leptin can direct neural development in a leptin receptor–independent manner
2024-11-25
Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. Although previous research has shown that the hormone leptin acts directly on hunger neurons through leptin receptors to promote the development of neural circuitry, results that will be published in PNAS on Nov. 25 indicate that certain neurons that do not express leptin receptors are nonetheless sensitive to its activity.
The research, led by the lab of Richard Simerly, Louise B. McGavock Professor and professor of molecular physiology ...
LAST 30 PRESS RELEASES:
Breakthrough in clean energy: Palladium nanosheets pave way for affordable hydrogen
Novel stem cell therapy repairs irreversible corneal damage in clinical trial
News article or big oil ad? As native advertisements mislead readers on climate change, Boston University experts identify interventions
Advanced genetic blueprint could unlock precision medicine
Study: World’s critical food crops at imminent risk from rising temperatures
Chemistry: Triple bond formed between boron and carbon for the first time
How a broken bone from arm wrestling led to a paradigm shift in mental health: Exercise as a first-line treatment for depression
Alarming levels of microplastics discovered in human brain tissue, linked to dementia
Global neurology leader makes The Neuro world's first open science institute
Alpha particle therapy emerges as a potent weapon against neuroendocrine tumours
Neuroscience beyond boundaries: Dr. Melissa Perreault bridges Indigenous knowledge and brain science
Giant clone of seaweed in the Baltic Sea
Motion capture: In world 1st, M. mobile’s motility apparatus clarified
One-third of older Canadians at nutritional risk, study finds
Enhancing climate action: satellite insights into fossil fuel CO2 emissions
Operating a virtual teaching and research section as an open source community: Practice and experience
Lack of medical oxygen affects millions
Business School celebrates triple crown
Can Rhizobium + low P increase the yield of common bean in Ethiopia?
Research Security Symposium on March 12
Special type of fat tissue could promote healthful longevity and help maintain exercise capacity in aging
Researchers develop high-water-soluble pyrene tetraone derivative to boost energy density of aqueous organic flow batteries
Who gets the lion’s share? HKU ecologists highlight disparities in global biodiversity conservation funding
HKU researchers unveil neuromorphic exposure control system to improve machine vision in extreme lighting environments
Researchers develop highly robust, reconfigurable, and mechanochromic cellulose photonic hydrogels
Researchers develop new in-cell ultraviolet photodissociation top-down mass spectrometry method
Researchers develop innovative tool for rapid pathogen detection
New insights into how cancer evades the immune system
3 Ways to reduce child sexual abuse rates
A third of children worldwide forecast to be obese or overweight by 2050
[Press-News.org] Antibiotics initiated for suspected community-acquired pneumonia even when chest radiography results are negativeRelationship between chest radiography results and antibiotic initiation in community-acquired pneumonia management by general practitioners