PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Antibiotics initiated for suspected community-acquired pneumonia even when chest radiography results are negative

Relationship between chest radiography results and antibiotic initiation in community-acquired pneumonia management by general practitioners

Antibiotics initiated for suspected community-acquired pneumonia even when chest radiography results are negative
2024-11-25
(Press-News.org) Original Research

Background and Goal: This study explored how chest X-ray results influence antibiotic initiation by general practitioners in France when managing patients with suspected pneumonia.

Study Approach: A prospective cross-sectional study was conducted with adult patients with suspected pneumonia who received chest X-rays as part of their evaluation. To analyze factors associated with antibiotic initiation, patients’ characteristics were compared at inclusion and at 28 days between patients with positive chest X-rays (indicating pneumonia) and patients with negative chest X-ray results.

Main Results: The sample included 259 adult patients. The median age was 58 years, 120 (46.3%) were male, 249 (96.1%) had not received antibiotics prior to inclusion, and 69 (26.7%) had at least one risk factor for pneumococcal disease.

Most of the general practitioners who included patients were women (55.2 %; n = 153), with a median age of 39 years. 76.1% (n = 210) were general practitioner trainers. 55.6% of patients (144 out of 259) had positive chest X-ray results. Patients with positive chest X-ray results had higher body temperature, faster heart rate, faster breathing rate, more difficulty breathing, and more frequent unilateral chest pain than patients with negative X-ray results, and their symptoms lasted for a longer time. 99.3% of patients with positive chest X-ray results received antibiotics. Despite fewer symptoms and negative chest X-ray results, a significant portion (68.75%) of patients with negative chest X-ray results were prescribed antibiotics (79/115 patients). Why It Matters: The findings of this study show that many general practitioners prescribe antibiotics for suspected community-acquired pneumonia even when chest X-ray results are negative, highlighting a gap between guidelines and actual practice. 

Relationship Between Chest Radiography Results and Antibiotic Initiation in Community-Acquired Pneumonia Management by General Practitioners

Juliette Pinot, MD, et al

Université Paris Cité and Université Sorbonne Paris Nord, INSERM, IAME, Paris, France

Université Paris Cité, Department of General Practice, Paris, France

PERMANENT LINK

Visual Abstract: 

 

END

[Attachments] See images for this press release:
Antibiotics initiated for suspected community-acquired pneumonia even when chest radiography results are negative

ELSE PRESS RELEASES FROM THIS DATE:

COVID-19 stay-at-home order increased reporting of food, housing, and other health-related social needs in Oregon

COVID-19 stay-at-home order increased reporting of food, housing, and other health-related social needs in Oregon
2024-11-25
Background and Goal: Efforts to address the health-related social needs (HRSN) of Medicare and Medicaid beneficiaries, such as housing and food, during the COVID-19 pandemic were insufficient. This research examined HRSN data from the Accountable Health Communities (AHC) study collected in Oregon to understand changes in HRSN for Medicare and Medicaid beneficiaries at the onset and during the first two years of the pandemic. Study Approach: The study sample included 21,522 Medicare and Medicaid beneficiaries screened for overall health-related social needs between ...

UW-led research links wildfire smoke exposure with increased dementia risk

2024-11-25
As Baby Boomers hit retirement, about 1 in 6 Americans is now over the age of 65. The number of Americans living with dementia is projected to skyrocket — but the proportion of older Americans who develop dementia has actually decreased. The exact reason why is uncertain, but various lifestyle and environmental factors can influence a person’s risk of cognitive decline.   One recently discovered risk is air pollution. Studies have linked exposure to a type of air pollution called fine particulate matter, or PM2.5, with an increased risk of developing dementia, and researchers suspect ...

Most U.S. adults surveyed trust store-bought turkey is free of contaminants, despite research finding fecal bacteria in ground turkey

2024-11-25
WASHINGTON, D.C. ؚ— More than six out of 10 U.S. adults who took part in a Physicians Committee for Responsible Medicine/Morning Consult survey last week say they wouldn’t eat turkey contaminated with feces, yet consumer research has shown more than half of store-bought packages of ground turkey tested positive for it. The poll included 2,183 adults interviewed Nov. 18 to Nov. 20, 82% of whom said they plan to eat turkey for Thanksgiving this year. Of those, 87% said they trust it’ll be free from contaminants, but 65% said if they knew it was contaminated with fecal bacteria, they’d be unlikely to eat it. In research conducted by Consumer Reports in ...

New therapy from UI Health offers FDA-approved treatment option for brittle type 1 diabetes

New therapy from UI Health offers FDA-approved treatment option for brittle type 1 diabetes
2024-11-25
A new therapy for brittle type 1 diabetes, the only treatment currently approved by the U.S. Food and Drug Administration, is available exclusively at UI Health in Chicago. Pancreatic islet cell therapy is a treatment approved by the FDA only for adults with type 1 diabetes who struggle to control their blood sugar levels due to frequent episodes of severe low blood sugar and hypoglycemia unawareness, a condition that occurs when patients can’t detect that their blood sugar is dropping. This new therapy, called Lantidra, is derived from a deceased donor pancreas. To regulate blood glucose, the drug is infused into the patient’s liver where insulin is produced. ...

Alzheimer's: A new strategy to prevent neurodegeneration

2024-11-25
A future treatment for Alzheimer disease may involve a nasal spray. Researchers at Università Cattolica and Fondazione Policlinico Universitario A. Gemelli IRCCS have discovered that by inhibiting the brain enzyme S-acyltransferase (zDHHC) through a nasal-spray drug, they can counteract the cognitive decline and brain damage typical of the disease. The study has been led by Professor Claudio Grassi, Director of the Neuroscience Department, and Professor Salvatore Fusco, with the collaboration of the University of Catania.   The researchers observed that the post-mortem brains of Alzheimer patients contained an excess of S-acyltransferase, ...

A clue to what lies beneath the bland surfaces of Uranus and Neptune

A clue to what lies beneath the bland surfaces of Uranus and Neptune
2024-11-25
Diamond rain? Super-ionic water? These are just two proposals that planetary scientists have come up with for what lies beneath the thick, bluish, hydrogen-and-helium atmospheres of Uranus and Neptune, our solar system's unique, but superficially bland, ice giants. A planetary scientist at the University of California, Berkeley, now proposes an alternative theory — that the interiors of both these planets are layered, and that the two layers, like oil and water, don't mix. That configuration neatly explains the planets' unusual magnetic fields and implies ...

Researchers uncover what makes large numbers of “squishy” grains start flowing

Researchers uncover what makes large numbers of “squishy” grains start flowing
2024-11-25
Researchers Samuel Poincloux (currently at Aoyama Gakuin University) and Kazumasa A. Takeuchi of the University of Tokyo have clarified the conditions under which large numbers of “squishy” grains, which can change their shape in response to external forces, transition from acting like a solid to acting like a liquid. Similar transitions occur in many biological processes, including the development of an embryo: cells are “squishy” biological “grains” that form solid tissues and sometimes flow to form different organs. Thus, the experimental and theoretical framework elaborated here will help separate the ...

Scientists uncover new mechanism in bacterial DNA enzyme opening pathways for antibiotic development

2024-11-25
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent in humans, plays a crucial role in supercoiling DNA, a necessary process for bacterial survival. Using high-resolution cryo-electron microscopy the researchers reveal unprecedented detail of gyrase’s action on DNA, potentially opening doors for new antibiotic therapies against resistant bacteria. The research is published in Proceedings of the ...

New study reveals the explosive secret of the squirting cucumber

New study reveals the explosive secret of the squirting cucumber
2024-11-25
UNDER EMBARGO UNTIL 20:00 GMT / 15:00 ET MONDAY 25 NOVEMBER 2024 New study reveals the explosive secret of the squirting cucumber IMAGES AND VIDEO AVAILABLE – SEE NOTES SECTION BELOW A team led by the University of Oxford has solved a mystery that has intrigued scientists for centuries: how does the squirting cucumber squirt? The findings, achieved through a combination of experiments, high-speed videography, image analysis, and advanced mathematical modelling, have been published today (25 November) in The Proceedings of the National Academy of Sciences (PNAS). The squirting cucumber (Ecballium elaterium, from the Greek ‘ekballein,’ meaning to throw out) is named for ...

Vanderbilt authors find evidence that the hunger hormone leptin can direct neural development in a leptin receptor–independent manner

Vanderbilt authors find evidence that the hunger hormone leptin can direct neural development in a leptin receptor–independent manner
2024-11-25
Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. Although previous research has shown that the hormone leptin acts directly on hunger neurons through leptin receptors to promote the development of neural circuitry, results that will be published in PNAS on Nov. 25 indicate that certain neurons that do not express leptin receptors are nonetheless sensitive to its activity. The research, led by the lab of Richard Simerly, Louise B. McGavock Professor and professor of molecular physiology ...

LAST 30 PRESS RELEASES:

‘Internal alarm system’ harnesses immune system against cancer

Stem cell transplant for stroke leads to brain cell growth and functional recovery in mice

Cleveland Clinic study shows greater long-term benefits of bariatric surgery compared to GLP-1 medicines

Revised diagnostic criteria for vascular cognitive impairment and dementia—The VasCog-2-WSO criteria

The ATREIDES program in search of lost exo-Neptunes

Ancient crop discovered in the Canary Islands thanks to archaeological DNA

Placental research may transform our understanding of autism and human brain evolution

Mapping the Universe, faster and with the same accuracy

Study isolates population aging as primary driver of musculoskeletal disorders

Designing a sulfur vacancy redox disruptor for photothermoelectric and cascade‑catalytic‑driven cuproptosis–ferroptosis–apoptosis therapy

Recent advances in dynamic biomacromolecular modifications and chemical interventions: Perspective from a Chinese chemical biology consortium

CRF and the Jon DeHaan Foundation to launch TCT AI Lab at TCT 2025

Canada’s fastest academic supercomputer is now online at SFU after $80m upgrades

Architecture’s past holds the key to sustainable future

Laser correction for short-sightedness is safe and effective for older teenagers

About one in five people taking Ozempic, Wegovy or Mounjaro say food tastes saltier or sweeter than before

Taking semaglutide turns down food noise, research suggests

Type 2 diabetes may double risk of sepsis, large community-based study suggests

New quantum sensors can withstand extreme pressure

Tirzepatide more cost-effective than semaglutide in patients with knee osteoarthritis and obesity

GLP-1 drugs shown cost-effective for knee osteoarthritis and obesity

Interactive apps, AI chatbots promote playfulness, reduce privacy concerns

How NIL boosts college football’s competitive balance

Moffitt researchers develop machine learning model to predict urgent care visits for lung cancer patients

Construction secrets of honeybees: Study reveals how bees build hives in tricky spots

Wheat disease losses total $2.9 billion across the United States and Canada between 2018 and 2021

New funding fuels development of first potentially regenerative treatment for multiple sclerosis

NJIT student–faculty team wins best presentation award for ant swarm simulation

Ants defend plants from herbivores but can hinder pollination

When the wireless data runs dry

[Press-News.org] Antibiotics initiated for suspected community-acquired pneumonia even when chest radiography results are negative
Relationship between chest radiography results and antibiotic initiation in community-acquired pneumonia management by general practitioners