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Disease severity staging system for NOTCH3-associated small vessel disease, including CADASIL

JAMA Neurology

2024-11-29
(Press-News.org)

About The Study: The findings of this study suggest the NOTCH3-associated small vessel disease (NOTCH3-SVD) staging system will help to better harmonize NOTCH3-SVD and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) cohort studies and registries; may improve individualized disease counseling, monitoring, and clinical management; and may facilitate patient stratification in clinical trials.

Corresponding Authors: To contact the corresponding authors, email Gido Gravesteijn, MD, PhD (g.gravesteijn@lumc.nl) and Saskia A. J. Lesnik Oberstein, MD, PhD (lesnik@lumc.nl).

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaneurol.2024.4487)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2024.4487?guestAccessKey=1159cb3b-9fd9-47ed-89c3-ffc0051dcb01&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=112924

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[Press-News.org] Disease severity staging system for NOTCH3-associated small vessel disease, including CADASIL
JAMA Neurology