(Press-News.org) About The Study: This systematic review and network meta-analysis of 601 eligible trials found that sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1 receptor agonists were associated with lower risk of major adverse cardiovascular events. Analysis of age × treatment interactions suggested that SGLT2 inhibitors were more cardioprotective in older than in younger people despite smaller reductions in hemoglobin A1c; GLP-1 receptor agonists were more cardioprotective in younger people.
Corresponding Author: To contact the corresponding author, Peter Hanlon, PhD, email peter.hanlon@glasgow.ac.uk.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2024.27402)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.27402?guestAccessKey=d9fad6f3-fe27-466e-be4c-ee5936e89378&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=020325
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Age and sex differences in efficacy of treatments for type 2 diabetes
JAMA
2025-02-03
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[Press-News.org] Age and sex differences in efficacy of treatments for type 2 diabetesJAMA