(Press-News.org) Many young and midcareer scientists in the U.S. are understandably anxious about potential cuts to government funding and the rise of junk science. Although your future in biomedicine may not be what you originally planned, it might actually become more interesting and filled with new possibilities and opportunities for innovation. Don’t think of this time to hunker down and disappear. Do the opposite with the understanding that you are more powerful and brilliant than you may realize.
In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology: https://plos.io/4bF93zK
Article title: Navigating your US bioscience career into the 2030s
Author countries: United States
Funding: The author received no specific funding for this work.
END
Navigating a US bioscience career despite anticipated cuts in funding for biomedicine
2025-03-28
ELSE PRESS RELEASES FROM THIS DATE:
How the failure of two dams amplified the Derna Flood tragedy
2025-03-28
A new study reveals that the devastating 2023 flood in Derna, Libya, was not merely the result of extreme rainfall but was drastically intensified by a major design shortcoming and its resulting collapse of two embankment dams. Through advanced hydrological modeling and satellite data analysis, researchers found that while Storm Daniel brought heavy rainfall, the catastrophe stemmed from dam failures and flawed risk assessment and communication—amplifying the destruction nearly twentyfold. The findings highlight the urgent need for improved flood mitigation strategies, especially in dryland regions where high uncertainty ...
Oral contraceptives and smoking impact steroid hormone levels in healthy adults
2025-03-28
Steroid hormone levels in healthy adults are influenced by oral contraceptives and smoking, as well as other lifestyle choices and factors such as biological sex and age, according to new research that has just been published in leading international journal Science Advances.
The objective of the research was to expand knowledge and understanding of steroid hormone levels, including corticoids and sex hormones, in healthy women and men over a broad age range. This is the first study to analyse such a large number of hormones in nearly 1,000 healthy people, filling a ...
C-Path’s predictive safety testing consortium advances a transformative test to detect drug induced liver injury
2025-03-28
TUCSON, Ariz., March 27, 2025 – Researchers from Critical Path Institute’s® (C-Path) Predictive Safety Testing Consortium have proposed glutamate dehydrogenase (GLDH) as a more liver-specific biomarker for detecting liver injury, supporting clearer decision-making. Currently, alanine aminotransferase and aspartate aminotransferase (ALT and AST) are considered the “gold standard” biomarkers in clinical practice and drug development. However, these biomarkers are not specific to the liver and can reflect changes in other tissues, which may lead to unclear diagnoses, particularly in individuals with muscle conditions ...
Green solvent innovation: high-speed doctor-blading boosts organic solar cell efficiency
2025-03-28
In a recent advancement, researchers have developed a high-speed doctor-blading technique that enhances the efficiency of organic solar cells (OSCs) while using eco-friendly, non-halogenated solvents. This innovative method not only addresses the environmental and scalability challenges of traditional solvents, such as chloroform, but also achieves impressive power conversion efficiencies (PCEs) of 18.20% and 17.36% with green solvents like o-xylene and toluene, respectively. With a module efficiency of 16.07%, this breakthrough sets the stage for more sustainable, ...
C-Path announces successful conclusion of the ECOA: getting better together initiative
2025-03-28
TUCSON, Ariz., March 26, 2025 – Critical Path Institute® (C-Path)Patient-Reported Outcome (PRO) Consortium and Electronic Clinical Outcome Assessment (eCOA) Consortium are pleased to announce the successful conclusion of the eCOA: Getting Better Together Initiative. This initiative, driven by a shared commitment to advancing patient-focused drug development, has culminated in meaningful, lasting changes that will benefit all stakeholders across the eCOA ecosystem.
Beginning in 2019, this C-Path-led collaborative, pre-competitive initiative brought ...
Brain channels ‘stopped in time’ reveal chemical flow that enables learning and thinking
2025-03-28
FOR IMMEDIATE RELEASE
In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most common signaling molecules, glutamate, opens a channel and allows a flood of charged particles to enter. The finding, which resulted from a study led by Johns Hopkins Medicine researchers, could advance the development of new drugs that block or open such signaling channels to treat conditions as varied as epilepsy and some intellectual disorders.
A report on the experiments, funded by the National ...
PET imaging confirms direct involvement of dopamine in cognitive flexibility
2025-03-28
Reston, VA (March 16, 2025)—For the first time, scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility, according to new research published in the March issue of The Journal of Nuclear Medicine. PET imaging shows that the brain increases dopamine production when completing cognitively demanding tasks, and that the more dopamine released, the more efficiently the tasks are completed. Armed with this information, physicians may soon be able to develop more precise treatment strategies for neurological and psychiatric disorders.
Cognitive flexibility is the ability to adapt one’s thinking and behavior appropriately to ...
Understanding the immune response to a persistent pathogen
2025-03-28
Most humans have long-lived infections in various tissues—including in the nervous system—that typically do not result in disease. The microbes associated with these infections enter a latent stage during which they quietly hide in cells, playing the long game to evade capture and ensure their own survival. But a lack of natural models to study these quiescent stages has led to gaps in scientists’ understanding of how latency contributes to pathogen persistence and whether these stages can be targeted by the immune system.
Now, a team led by University of Pennsylvania School of Veterinary Medicine researchers ...
GSA conducting April 1 congressional briefing on impact of obesity as we age
2025-03-28
The Gerontological Society of America (GSA) invites you to a congressional briefing:
Title: The Impact of Obesity and Opportunity for CMS to Address
When: Tuesday, April 1, from 12 to 1 p.m. ET
Where: Virtual
Click to RSVP
GSA is a professional membership organization committed to promoting the best available interdisciplinary aging research to advance innovations in practice and policy. This is especially key to managing the chronic condition of obesity in health care.
Older people with obesity and overweight require access to proven treatment options and care to improve overall health and reduce other related health care costs. ...
Professor receives pilot funding to conduct study to increase forest farming in Appalachia
2025-03-28
Appalachia is globally recognized as a key supplier of non-timber forest products (NTFPs) with growing demand for its resources. Nearly half of the woodland medicinal species in the global nutraceutical market come from the region, contributing to a multibillion-dollar industry.
Species such as ginseng, slippery elm, and black cohosh are prominent understory sources of medicinal material. Appalachian edible products are also gaining popularity beyond the region. Ramps, a wild Appalachian plant, can sell for more than $20 per pound in places such as New York City.
Spanning 205,000 square miles, Appalachia is home to over ...