(Press-News.org) Doctors were nearly 15 times more likely to follow allergy-prevention guidelines with new tools
Tools included a training video and health record prompts for doctors and handouts for families
Randomized trial included 30 pediatric practices and 18,480 infant visits
CHICAGO --- A few easy-to-implement tools — a training video, electronic health record prompts and handouts for families — greatly increased how often pediatricians recommended early peanut introduction to infants, reports a new clinical study led by Northwestern University and Ann & Robert H. Lurie Children's Hospital of Chicago.
Since 2017, national guidelines have encouraged pediatricians to recommend introducing peanut-containing foods around 4 to 6 months of age to reduce peanut allergies. Yet, surveys show that few pediatricians strictly follow these guidelines. Peanut allergy, the most common pediatric food allergy, is on the rise and affects more than 2% of children in the U.S.
In the study, guideline adherence was 84% for low-risk infants (no eczema and no egg allergy) in practices that used the tools, compared with 35% in clinics that did not. Infants in the intervention group were nearly 15 times more likely to receive guidelines-based care.
“We found that supporting pediatricians with training, electronic health record prompts and educational materials for parents significantly improved their ability to counsel families on early peanut introduction,” said lead author Dr. Ruchi Gupta, professor of pediatrics and medicine at Northwestern University Feinberg School of Medicine and pediatrician at Lurie Children’s.
“Because pediatric visits at 4 and 6 months are so busy, this support is critical to ensure families receive clear guidance,” Gupta added. “Our hope is that these conversations will help parents feel confident introducing peanut products early. We want to reverse the trend of increasing food allergies in the U.S. through prevention.”
The study will publish on Monday (Oct. 6) in the journal Pediatrics.
How the study was conducted
The randomized trial included 30 pediatric practices in the Chicago and Peoria, Illinois, regions, spanning federally qualified health centers, private clinics and academic practices. Intervention practices received a clinician training video, electronic health record prompts, visual aids for parents and a scorecard to identify severe eczema; control practices did not.
The primary outcome was clinician adherence to guidelines, documented in the electronic health record (EHR) data at the 4- or 6-month well-child visit. In total, 18,480 infants were seen by 290 clinicians. In total, 18,480 infants were seen by 290 clinicians.
Lucy Bilaver, lead statistician for the study and associate professor of pediatrics at Feinberg noted the importance of leveraging EHR data for this pragmatic trial. “We were able to measure the primary outcome by making use of the clinical notes and structured data that pediatric clinicians generate during these well-child visits,” she said.
The findings
Among low-risk infants, guideline adherence was 84% in the intervention group versus 35% in controls. For high-risk infants, adherence was 27% in the intervention group versus 10% in controls. In addition, 36% of high-risk infants in the intervention group were referred to an allergist or given an allergy test, compared with 10% in the control group.
“While more work is needed, the success of this intervention supports wider dissemination to prevent peanut allergy in children,” Gupta said.
Outcomes in the trial will be tracked until children are 2.5 years old to see if the intervention reduces actual peanut allergy prevalence.
What parents need to know
Since 2017, national guidelines have recommended introducing peanut-containing foods around 4 to 6 months of age — a major shift prompted by a landmark clinical trial that showed early introduction cuts peanut allergy risk by more than 80%. Before that, parents were often told to delay peanut feeding out of concern it might trigger allergies.
When your baby is developmentally ready to start solids, peanut products can be introduced, according to the study authors. (Instructions for how to do this are linked here.) Early introduction of egg and other common allergenic foods is also encouraged, based on family preference.
The study, titled “Pediatric Clinician Adherence to Peanut Allergy Prevention Guidelines: A Randomized Trial,” was funded by the National Institute of Allergy and Infectious Diseases (NIAID U01AI138907).
END
New tools boost pediatricians’ adherence to peanut allergy guidelines 15-fold
Introducing peanut-containing foods to infants can cut peanut allergy risk by more than 80%
2025-10-06
ELSE PRESS RELEASES FROM THIS DATE:
Research unearths origins of Ancient Egypt’s Karnak Temple
2025-10-05
UNDER EMBARGO UNTIL 00:01AM UK TIME ON MONDAY 6 OCTOBER 2025
Research unearths origins of Ancient Egypt’s Karnak Temple
Most complete study of the temple complex and its landscape establishes earliest occupation and hints at link to creation myth
Researchers have carried out the most comprehensive geoarchaeological survey of Egypt’s Karnak Temple near Luxor – one of the ancient world’s largest temple complexes and a UNESCO World Heritage site welcoming millions of tourists every year.
The study, published in Antiquity today [6 October] reveals new evidence on the ...
Reevaluating nonoperative management for pediatric uncomplicated acute appendicitis
2025-10-05
About The Study: In contrast to earlier studies, this meta-analysis found significantly higher treatment failure and major complication rates within a year with nonoperative management among children and adolescents. The meta-analysis provides pediatricians and pediatric surgeons with up-to-date data to inform shared decision-making with families and encourage individualized, patient-centered treatment.
Corresponding Author: To contact the corresponding author, Isabella Faria, MD, email imdefrei@utmb.edu.
To access the embargoed ...
Metabolically active visceral fat linked to aggressive endometrial cancer, new study reveals
2025-10-04
(Barcelona, Spain, Sunday 5 October 2025) High metabolic activity of visceral fat may be associated with more aggressive endometrial cancer, new research presented today at the 38th Annual Congress of the European Association of Nuclear Medicine (EANM'25) has shown.1
While obesity is a recognised risk factor for endometrial cancer,2-3 the findings indicate that disease aggressiveness may be driven not only by the amount of visceral fat but also by its metabolic activity. Visceral fat is the fat that surrounds the internal organs, and to a larger degree than subcutaneous ...
Scientists glimpse how enzymes “dance” while they work, and why that’s important
2025-10-04
Tokyo, Japan – Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex molecular machinery like enzymes move while they help catalyze reactions. Focusing on an enzyme in yeast, they demonstrated how contrasts in atomic scale motions impact their function. The method promises unprecedented access to the mechanisms by which biomolecules work, and how they relate to illnesses.
Enzymes are indispensable to the function of all biological organisms, ...
California partnership aided COVID-19 response and health equity, report finds
2025-10-03
RIVERSIDE, Calif. -- The COVID-19 pandemic did not affect everyone equally. Communities of color, especially Latino (including undocumented persons), Black, and Native American groups, as well as people with low incomes, experienced much higher rates of infection, hospitalization, and death.
Research has shown that several key factors worsened health inequalities during the COVID-19 pandemic. Crowded housing, dense neighborhoods, and location played a major role in how the virus spread. Systemic racism, discrimination, and unstable jobs made some communities even more at risk.
A new report, published in Health Expectations, highlights how ...
University of Oklahoma secures $19.9 million for revolutionary radar technology
2025-10-03
NORMAN, Okla. – Researchers at the University of Oklahoma’s Advanced Radar Research Center (ARRC) continue to lead the way in radar innovation. A $19.9 million award from the U.S. National Science Foundation’s Mid-scale Research Infrastructure-1 program will fund the development of two groundbreaking KaRVIR systems (Dual-Doppler 3D Mobile Ka-band Rapid-Scanning Volume Imaging Radars for Earth System Science). These state-of-the-art radars will provide unique capabilities to close critical observational gaps in the atmospheric ...
Study finds restoring order to dividing cancer cells may prevent metastasis
2025-10-03
Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from spreading. Researchers have discovered that an enzyme called EZH2 drives TNBC cells to divide abnormally, which enables them to relocate to distant organs. The preclinical study also found drugs that block EZH2 could restore order to dividing cells and thwart the spread of TNBC cells.
“Metastasis is the main reason patients with triple negative breast cancer face poor survival odds,” said senior author Dr. Vivek Mittal, Ford-Isom Research Professor of Cardiothoracic Surgery and ...
High-accuracy tumor detection with label-free microscopy and neural networks
2025-10-03
Pancreatic neuroendocrine neoplasms (PNENs) are a rare form of cancer that affects hormone-producing cells in the pancreas. Although uncommon, their incidence has been rising steadily over the past few decades. Treatment options include chemotherapy and targeted therapies, but surgery remains the only chance for a cure. However, surgical decisions often depend on pathology results that can take hours or even days, delaying treatment and increasing the risk of incomplete tumor removal.
Researchers at the University of Arizona have developed a new imaging method that could help surgeons identify cancerous tissue more quickly and accurately. The technique, called multiphoton microscopy ...
Wayne State research reveals fetuses exposed to Zika virus have long-term immune challenges
2025-10-03
DETROIT — A Wayne State University study published in the Oct. 3, 2025, issue of Nature Communications revealed that Zika virus exposure during pregnancy causes long-term, sex-specific changes to a baby’s immune system, particularly affecting the frontline immune cells that fight infection.
The study, “Prenatal exposure to Zika virus shapes offspring neutrophil function in a sex-specific manner,” was led by Dr. Jiahui Ding, assistant professor of obstetrics and gynecology in Wayne State’s School of Medicine.
“We discovered that when a pregnant mother is infected with Zika virus, the resulting inflammatory ...
Researchers deconstruct chikungunya outbreaks to improve prediction and vaccine development
2025-10-03
The symptoms come on quickly — acute fever, followed by debilitating joint pain that can last for months. Though rarely fatal, the chikungunya virus, a mosquito-borne illness, can be particularly severe for high-risk individuals, including newborns and older adults.
While the virus is common in tropical and subtropical regions, including Asia, Africa and South America, public health officials have been tracking reported infections in Europe and, in September, a confirmed case in Long Island, New York.
Outbreaks ...
LAST 30 PRESS RELEASES:
Ultrathin gallium nitride quantum‑disk‑in‑nanowire‑enabled reconfigurable bioinspired sensor for high‑accuracy human action recognition
First high-precision measurement of potential dynamics inside reactor-grade fusion plasma
Study: A cellular protein, FGD3, boosts breast cancer chemotherapy, immunotherapy
Common gout drug may reduce risk of heart attack and stroke
Headache disorders affect 3 billion people worldwide—nearly one in every three people, ranking sixth for health loss in 2023
Mayo Clinic scientists create tool to predict Alzheimer's risk years before symptoms begin
Extending anti-clotting treatment linked to lower rates of new clots
E-cigarettes compromise children’s human rights
The Lancet Child & Adolescent Health: High blood pressure in children and adolescents nearly doubled between 2000 and 2020, suggests largest global study to date
EuTYPH-C Inj.® Multi-dose demonstrates strong safety and immunogenicity: Results now available from a Phase 3 study
Fossil fuel CO2 emissions hit record high in 2025
Bold action needed to fix NHS clinical placement crisis
Six strategies to reinvigorate the doctor-patient bedside encounter
Mount Sinai study reveals why some myeloma patients stay cancer-free for years after CAR T therapy
How climate change brings wildlife to the yard
Plants balance adaptability in skin cells with stability in sex cells
UH Wolff Center for Entrepreneurship ranked No. 1 for seventh consecutive year
New study reveals long-term impacts on Stevens-Johnson syndrome survivors
New study reveals how your income may shape your risk of dementia
Texas A&M researchers use AI to identify genetic ‘time capsule’ that distinguishes species
Rainfall and temperature shape mosquito fauna in Atlantic Forest bromeliads, including malaria vectors
Scientists move closer to better pancreatic cancer treatments
Three Tufts professors are named top researchers in the world
New angio-CT technology integrates cutting-edge imaging to enhance patient care
Mechanical power by linking Earth’s warmth to space
The vast North American Phosphoria Rock Complex might be rich in silica because it was home to millions of sea sponges almost 300 million years ago, whose fossils were misdiagnosed until now
The link between air pollution and breast cancer is weakened in greener environments, suggests study using UK Biobank data
Dutch Afghanistan veterans with battle-related injuries report a similar physical and psychological quality of life as they did five years prior in a ten-year follow-up study
Loneliness in young adults - especially educated females - often coexists alongside friendship and social connectedness, and might instead be linked with experiencing major life changes, per large US
Bacteriophage characterization provides platform for rational design
[Press-News.org] New tools boost pediatricians’ adherence to peanut allergy guidelines 15-foldIntroducing peanut-containing foods to infants can cut peanut allergy risk by more than 80%