(Press-News.org) SEATTLE – A landmark breast health care publication reveals a multitude of barriers that keep women of developing nations from being screened and treated for breast cancer – but offers tools to help countries improve their breast care programs.
"Global Breast Health Care: Optimizing Delivery in Low- and Middle-Resource Countries," published as a supplement to the April 1 edition of The Breast, compiles three consensus statements and 11 research papers that were based on projects and proposals presented last June at the Breast Health Global Initiative Global Summit on International Breast Health in Chicago. The summit brought together more than 150 experts from 43 countries. An executive summary of the consensus statements was published simultaneously in the April 1 edition of The Lancet Oncology.
Benjamin O. Anderson, M.D., BHGI chair and director, said the publication of breast cancer studies from low- and middle-resource countries that are easily accessible has been a longtime goal of the organization.
"These papers collectively provide insight into the societal norms, economic challenges and public policy issues of the low- and middle-resource countries," Anderson said. "They also provide models for how to improve and optimize breast health care and cancer treatment programs," he said. Anderson is a member of the Public Health Sciences Division at Fred Hutchinson Cancer Research Center and a professor of surgery at the University of Washington School of Medicine.
The supplement includes studies conducted in regions rarely researched in this context – Kashmir and Gaza Strip – and new studies from Nigeria, Malaysia and Mexico.
In the study involving war-torn Gaza, researchers found significant differences between expatriates and Gaza residents regarding breast cancer beliefs and health care- seeking behaviors, despite religious, cultural and personal similarities between the two groups. Misconceptions about – and access to – mammography services turned out to be major factors in determining who sought care.
In Kasmir, researchers worked to collect public health information and provide breast cancer awareness information and breast cancer screening to 520 women from five villages. This study provided a much needed model for combining public health outreach with breast cancer awareness and cancer screening.
In Nigeria, a study of 275 women found about 30 percent refused a diagnostic biopsy, and more than half said no to a recommended breast surgery. Researchers found that patients were thwarted by multiple barriers, including having to deliver their own biopsies to labs for processing, procure their own cancer drugs and pay in advance for procedures, including surgery.
Infrastructure barriers to treatment can exist alongside free health care. A report from Mexico found that women who suspected they had breast cancer when they visited a public clinic had to return an average of nearly seven times and wait more than six months before receiving a definitive diagnosis and treatment.
The supplement contains the first global consensus report on breast cancer in low- resource countries, which was written by 17 breast cancer experts from 12 countries. The report identifies problems common to low-resource countries by addressing key questions about breast cancer awareness, diagnosis and treatment in this economically constrained global community. While low-income countries have diverse geographical, political and socio-cultural profiles, they have similar economic and development constraints.
Key problems identified in low-resource countries include lack of public awareness and misconceptions about breast cancer, lack of pathology services to establish hormone status of tumors; treatment options limited by available equipment and drugs, a need for health professional training; and a need for supportive care services (such as side-effect treatment, palliative care and end-of-life care).
Researchers identified common strategies that can be used for improving breast cancer care in these settings. The Breast supplement provides detailed models of new programs that have improved breast cancer care in low-resource countries and middle income countries, including mammography patient interventions in Chile and an integrated information system in Brazil that ties reimbursement of providers for mammography services to data collection.
###
About the Breast Health Global Initiative
Established in 2002, Seattle-based BHGI is a global alliance co-sponsored by Fred Hutchinson Cancer Research Center and Susan G. Komen for the Cure® and internationally recognized for its pioneering work to develop "best practices with limited resources" guidelines for breast cancer. For more information, visit www.bhgi.info .
MEDIA CONTACTS:
Dean Forbes
dforbes@fhcrc.org
206-667-2896
Sandra Distelhorst
sdistelh@fhcrc.org
206-290-9938
Breast health global initiative offers unprecedented tools for developing nations
New research identifies diverse -- but not insurmountable -- barriers to breast cancer screening and treatment
2011-04-02
ELSE PRESS RELEASES FROM THIS DATE:
Many US women have children by more than one man
2011-04-02
ANN ARBOR, Mich.---The first national study of the prevalence of multiple partner fertility shows that 28 percent of all U.S. women with two or more children have children by more than one man.
The study will be presented April 1 in Washington, D.C., at the annual meeting of the Population Association of America.
"I was surprised at the prevalence," said demographer Cassandra Dorius, a postdoctoral fellow at the University of Michigan Institute for Social Research. "Multiple partner fertility is an important part of contemporary American family life, and a key component ...
The Population Bomb: How we survived it
2011-04-02
ANN ARBOR, Mich.---World population will reach 7 billion this year, prompting new concerns about whether the world will soon face a major population crisis.
"In spite of 50 years of the fastest population growth on record, the world did remarkably well in producing enough food and reducing poverty," said University of Michigan economist David Lam, in his presidential address at the annual meeting of the Population Association of America.
Lam is a professor of economics and a research professor at the U-M Institute for Social Research. The talk is titled "How the World ...
Manage biological invasions like natural disasters, biologists say
2011-04-02
Biological invasions get less prime-time coverage than natural disasters, but may be more economically damaging and warrant corresponding investments in preparedness and response planning, according to three biologists writing in the April issue of BioScience.
Anthony Ricciardi of McGill University and his coauthors point out that species invasions are becoming more frequent worldwide, largely because of international trade. Although many alien species establish themselves in a new location without causing harm, the worst biological invasions may cause multiple extinctions ...
Cat's out of the bag: PUMA contributes to ulcerative colitis
2011-04-02
Ulcerative colitis (UC) is an inflammatory bowel disease thought to be related to aberrant activation of the immune system in the intestine. Recent research has also suggested that regulated cell death (apoptosis) of the intestinal epithelial cells is a contributing factor to the pathogenesis. However, the molecular mechanisms that control the cellular response to inflammation are incompletely understood.
In this paper, Lin Zhang, at the University of Pittsburgh, in Pennsylvania, found that in mice, a protein called PUMA (p53 upregulated modulator of apoptosis) was responsible ...
Gag order: how DNA silencing can promote cancer
2011-04-02
Cells control which genes they express by multiple mechanisms, one of which is the direct modification of DNA with small molecules. Methylation of genes effectively silences them, and excess DNA methylation, particularly of genes that control the cell cycle, is known to promote cancer formation. However, it is unclear whether the enzymes that modify DNA in this way target specific genes or whether random modifications select cells for enhanced tumorigenic capactiy.
In new research, Rudolf Jaenisch and colleagues, at the Whitehead Institute in Cambridge, Massachusetts, ...
JCI online early table of contents: April 1, 2011
2011-04-02
EDITOR'S PICK
Cat's out of the bag: PUMA contributes to ulcerative colitis
Ulcerative colitis (UC) is an inflammatory bowel disease thought to be related to aberrant activation of the immune system in the intestine. Recent research has also suggested that regulated cell death (apoptosis) of the intestinal epithelial cells is a contributing factor to the pathogenesis. However, the molecular mechanisms that control the cellular response to inflammation are incompletely understood.
In this paper, Lin Zhang, at the University of Pittsburgh, in Pennsylvania, found that in ...
Sugar-grain sized meteorites rocked the climates of early Earth and Mars, according to new study
2011-04-02
Bombardments of 'micro-meteorites' on Earth and Mars four billion years ago may have caused the planets' climates to cool dramatically, hampering their ability to support life, according to research published today in the journal Geochimica et Cosmochimica Acta.
Scientists from Imperial College London studied the effects of the Late Heavy Bombardment (LHB), a period of time in the early Solar System when meteorite showers lasting around 100 million years barraged Earth and Mars. This bombardment discharged sulphur dioxide into the upper atmospheres of both planets and ...
Smyrna, GA Dentist Reaches Out to Patients Through New Website
2011-04-02
Leading dentists in Smyrna, Dr. James C. Pitts and Dr. Joseph M. Pitts, are pleased to introduce patients to a new avenue for communication and education through the launch of the practice's innovative website. The new informative website was created in order to enhance patient awareness of dental health care.
The new website for this dentist in Smyrna offers a wide array of valuable tools and information that patients can use to better inform themselves of various dental health care topics. Patients can visit this Smyrna dentist's website via the Internet at any moment ...
From science fiction to research breakthrough
2011-04-02
Focusing on interdisciplinary research is now leading to breakthroughs in bio nanotechnology research. A new method for drug development has become a reality.
Four years ago, the biologist Karen Martinez almost didn't believe in the research project herself when she started with her team working on it, but now it has been proven. Together with colleagues at the Nano-Science Center, her team has been able to combine nanoscale materials and technologies that are traditionally used for electronic devices with individual living cells. The researchers have shown that cells ...
Progress toward the clinical application of autologous induced pluripotent stem cells and gene repair therapy for treatment of familial hypercholesterolemia
2011-04-02
Study shows, for the first time, the successful reprogramming of diseased human hepatocytes into induced pluripotent stem cells (iPSC).1
Results also found differentiation into mature hepatocytes was more efficient than that with fibroblast-derived iPSCs.
The generation of diseased hepatocyte-derived human iPSC lines provides a good basis for the study of liver disease pathogenesis.
Such technology could give a potentially unlimited reservoir of cells for the treatment of human liver diseases: generating genetically corrected liver cells via auto-transplantation of ...
LAST 30 PRESS RELEASES:
Twelve questions to ask your doctor for better brain health in the new year
Microelectronics Science Research Centers to lead charge on next-generation designs and prototypes
Study identifies genetic cause for yellow nail syndrome
New drug to prevent migraine may start working right away
Good news for people with MS: COVID-19 infection not tied to worsening symptoms
Department of Energy announces $179 million for Microelectronics Science Research Centers
Human-related activities continue to threaten global climate and productivity
Public shows greater acceptance of RSV vaccine as vaccine hesitancy appears to have plateaued
Unraveling the power and influence of language
Gene editing tool reduces Alzheimer’s plaque precursor in mice
TNF inhibitors prevent complications in kids with Crohn's disease, recommended as first-line therapies
Twisted Edison: Bright, elliptically polarized incandescent light
Structural cell protein also directly regulates gene transcription
Breaking boundaries: Researchers isolate quantum coherence in classical light systems
Brain map clarifies neuronal connectivity behind motor function
Researchers find compromised indoor air in homes following Marshall Fire
Months after Colorado's Marshall Fire, residents of surviving homes reported health symptoms, poor air quality
Identification of chemical constituents and blood-absorbed components of Shenqi Fuzheng extract based on UPLC-triple-TOF/MS technology
'Glass fences' hinder Japanese female faculty in international research, study finds
Vector winds forecast by numerical weather prediction models still in need of optimization
New research identifies key cellular mechanism driving Alzheimer’s disease
Trends in buprenorphine dispensing among adolescents and young adults in the US
Emergency department physicians vary widely in their likelihood of hospitalizing a patient, even within the same facility
Firearm and motor vehicle pediatric deaths— intersections of age, sex, race, and ethnicity
Association of state cannabis legalization with cannabis use disorder and cannabis poisoning
Gestational hypertension, preeclampsia, and eclampsia and future neurological disorders
Adoption of “hospital-at-home” programs remains concentrated among larger, urban, not-for-profit and academic hospitals
Unlocking the mysteries of the human gut
High-quality nanodiamonds for bioimaging and quantum sensing applications
New clinical practice guideline on the process for diagnosing Alzheimer’s disease or a related form of cognitive impairment or dementia
[Press-News.org] Breast health global initiative offers unprecedented tools for developing nationsNew research identifies diverse -- but not insurmountable -- barriers to breast cancer screening and treatment