PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Anti-Muellerian hormone predicts IVF success

High hormone levels signal increased likelihood of pregnancy, birth

2013-02-12
(Press-News.org) Chevy Chase, MD ––Women with a high concentration of anti-Müllerian hormone stand a better chance of giving birth after in vitro fertilization, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

Anti-Müllerian hormone (AMH) is produced by the ovaries. The study found women with high AMH levels were 2.5 times more likely to have a successful IVF cycle than women of a similar age with low levels of the hormone. AMH levels were a predictor of pregnancy and live birth, even when the mother's age and egg production were taken into account.

Although a growing body of research has pinpointed AMH levels as an indicator of the number of eggs remaining in a woman's ovaries, this study is the first to demonstrate AMH levels are directly connected to birth and pregnancy rates, regardless of the number of eggs retrieved.

"For women who are struggling to get pregnant, a high AMH level should be very reassuring," said Thomas Brodin, MD, of Uppsala University in Sweden and lead author of the study. "High levels of this hormone mean there is a greater chance they have plenty of healthy eggs remaining to support a pregnancy."

Researchers concluded high AMH levels are associated with successful IVF treatment because the hormone levels reveal important information about the quality as well as the quantity of eggs left in a woman's ovaries. Women who have high AMH levels are likely to have a high proportion of eggs capable of developing into healthy embryos, Brodin said.

The prospective cohort study tracked 892 women who underwent IVF treatment at the Carl von Linné Clinic in Uppsala between 2008 and 2011. The participants underwent a total of 1,230 IVF cycles. AMH levels in the participants' blood were measured prior to treatment.

The study found that women were more likely to have a successful treatment outcome as their AMH levels increased. Women who had AMH levels above 2.94 ng/ml had the highest birth rates. The effect leveled out when AMH levels surpassed 5 ng/ml.

Although researchers did not find a cut-off point below which women could not get pregnant, IVF success rates dropped substantially as AMH levels declined. Among the study participants who had AMH levels below 0.2 ng/ml, 53 IVF cycles resulted in only 18 embryo transfers and the birth of three children.

The study found reason for optimism among women who have polycystic ovary syndrome, a condition normally associated with ovulation problems. Women who have this condition tend to have high AMH levels.

"Our data suggests women who have polycystic ovaries are likely to be good candidates for IVF," Brodin said. "Along with high AMH levels, this group tends to have a significant supply of eggs remaining in the ovaries."

INFORMATION:

Other researchers working on the study include: N. Hadziosmanovic and L. Berglund of Uppsala Clinical Research Center, and M. Olovsson and J. Holte of Uppsala University.

The article, "Anti-Müllerian Hormone Levels Are Strongly Associated with Live-birth Rates after Assisted Reproduction," appears in the March 2013 issue of JCEM.

END



ELSE PRESS RELEASES FROM THIS DATE:

Cardiovascular risk may remain for treated Cushing's disease patients

2013-02-12
Chevy Chase, MD ––Even after successful treatment, patients with Cushing's disease who were older when diagnosed or had prolonged exposure to excess cortisol face a greater risk of dying or developing cardiovascular disease, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). Cushing's disease is a rare condition where the body is exposed to excess cortisol – a stress hormone produced in the adrenal gland – for long periods of time. Researchers have long known that patients who have ...

Birth order linked to increased risk of diabetes, metabolic disorders

2013-02-12
Chevy Chase, MD ––Long a source of sibling rivalry, birth order may raise the risk of first-born children developing diabetes or high blood pressure, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). First-born children have greater difficulty absorbing sugars into the body and have higher daytime blood pressure than children who have older siblings, according to the study conducted at the University of Auckland's Liggins Institute in New Zealand. The study was the first to document a ...

African-American, Caucasian women should take identical vitamin D doses

2013-02-12
Chevy Chase, MD ––African-American women battling vitamin D deficiencies need the same dose as Caucasian women to treat the condition, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). Although women with darker skin tones tend to have lower levels of the biomarker used to measure Vitamin D levels, called 25-hydroxyvitamin D or 25OHD, the study found that older African-American and Caucasian women responded in the same way when they received vitamin D supplements. Unlike many vitamins ...

New study examines victims and cyberstalking

2013-02-12
HUNTSVILLE, TEXAS (2/12/13) -- Victims of cyberstalking take more self-protective measures, pay higher out-of-pocket costs to combat the problem and experience greater fear over time than traditional stalking victims, said Matt Nobles of Sam Houston State University. Nobles, along with Bradford Reyns of Weber State University, Kathleen Fox of Arizona State University and Bonnie Fisher of the University of Cincinnati, recently published "Protection Against Pursuit: A Conceptual and Empirical Comparison of Cyberstalking and Stalking Victimization Among a National Sample" ...

Artist Steve Wilda Receives Grand Prize Award in International Juried Art Competition

2013-02-12
The Anniversary II Art Contest & Exhibit was an open theme, and artists from around the world were invited to enter. This exhibit is comprised of many deserving works in a range of mediums and styles. Best in show was awarded to Steve Wilda for his masterful acrylic painting, which puts a contemporary twist on still life paintings that evoke the Dutch master's and adds the theme of decay. 2nd place went to Tai Taealii, whose fascinating piece is made of a variety of materials (ballpoint pen, spraypaint, stencils and marker inks) and references an equally wide ...

EYES IN Releases Issue 16 of Their Award Winning Digital Magazine

2013-02-12
During her travels to the world's greatest fashion shows in Paris, Milan, and London, to the film festivals in Park City, Berlin and Cannes, to the art & design shows in Miami, Basel, Milan, and Hong Kong and to a range of global health, beauty and science seminars, Editor-in-Chief and President of EYES IN Vivian Van Dijk finds the most compelling individuals to profile since launching EYES IN Magazine in late 2010. Specifically magnifying stories from New York to Russia, Denmark and all the way to Argentina, Issue 16 of EYES IN Magazine features stories from Music ...

Capital Sign Solutions Helps PDQ Retain Corporate Branding with Creative Exterior Signage Solution

2013-02-12
Capital Sign Solutions has completed what is probably its most creative and ambitious project to date. The Raleigh signage company worked closely with PDQ, a restaurant that recently opened in Sutton Square on Falls of Neuse Road in Raleigh, to redesign elements of the restaurant's building design in order to house the company's logo indoors in order to retain its corporate branding. Current property covenants would have required PDQ to change the colors of its outdoor signage. Capital Sign Solutions founder and President, Patrick Mills, said his company was brought ...

New School Finalizing Curriculum Adoption

2013-02-12
What differentiates Trinity Preparatory Academy from other private schools? The Board of Directors and founding families are dedicated to ensuring that the Christian worldview reaches across all subject areas and is incorporated into every aspect of the educational experience at Trinity Prep. One way that Trinity Preparatory Academy is incorporating the Christian worldview is by adopting curricula not separated from God. Kristine Poland, Head of Family Ministries states, "We believe that faith and learning are inseparable. This belief is the basis for every curriculum ...

Legendary Monsters Toys Invade!

2013-02-12
Nevermore Toys is headed by R. Todd Broadwater, Owner and Design Director of the studio. Broadwater has more than 13 years' experience in the toy and game industry, recently lending his talents to such titles as XCOM: Enemy Unknown, Fallout 3 and Oblivion. "Our experiences with the unknown live on and are still a part of the curiosity and wonder that exist within us today," says Broadwater. "It is my pleasure to share these stories with children and adults in the form of these collectible toys." Broadwater has spent a number of years researching ...

WeezLabs, Inc. Launches iDesk App

2013-02-12
WeezLabs, Inc., a leading developer of websites, databases and mobile applications for iOS and Android smart devices, has launched iDesk (https://itunes.apple.com/app/id571274830), a mobile app that makes it easy for employers and workers, including contractors, consultants and freelancers, to monitor and maximize time spent on the job. iDesk provides all registered users of oDesk.com with the functionality of the oDesk website, the world's largest online workplace, via an elegant and smart iPad and iPad Mini application. The app is ideal for any type of professional ...

LAST 30 PRESS RELEASES:

Are lifetimes of big appliances really shrinking?

Pink skies

Monkeys are world’s best yodellers - new research

Key differences between visual- and memory-led Alzheimer’s discovered

% weight loss targets in obesity management – is this the wrong objective?

An app can change how you see yourself at work

NYC speed cameras take six months to change driver behavior, effects vary by neighborhood, new study reveals

New research shows that propaganda is on the rise in China

Even the richest Americans face shorter lifespans than their European counterparts, study finds

Novel genes linked to rare childhood diarrhea

New computer model reveals how Bronze Age Scandinavians could have crossed the sea

Novel point-of-care technology delivers accurate HIV results in minutes

Researchers reveal key brain differences to explain why Ritalin helps improve focus in some more than others

Study finds nearly five-fold increase in hospitalizations for common cause of stroke

Study reveals how alcohol abuse damages cognition

Medicinal cannabis is linked to long-term benefits in health-related quality of life

Microplastics detected in cat placentas and fetuses during early pregnancy

Ancient amphibians as big as alligators died in mass mortality event in Triassic Wyoming

Scientists uncover the first clear evidence of air sacs in the fossilized bones of alvarezsaurian dinosaurs: the "hollow bones" which help modern day birds to fly

Alcohol makes male flies sexy

TB patients globally often incur "catastrophic costs" of up to $11,329 USD, despite many countries offering free treatment, with predominant drivers of cost being hospitalization and loss of income

Study links teen girls’ screen time to sleep disruptions and depression

Scientists unveil starfish-inspired wearable tech for heart monitoring

Footprints reveal prehistoric Scottish lagoons were stomping grounds for giant Jurassic dinosaurs

AI effectively predicts dementia risk in American Indian/Alaska Native elders

First guideline on newborn screening for cystic fibrosis calls for changes in practice to improve outcomes

Existing international law can help secure peace and security in outer space, study shows

Pinning down the process of West Nile virus transmission

UTA-backed research tackles health challenges across ages

In pancreatic cancer, a race against time

[Press-News.org] Anti-Muellerian hormone predicts IVF success
High hormone levels signal increased likelihood of pregnancy, birth