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Researchers find thousands of pediatric firearm deaths linked to more permissive state gun laws

2025-06-09
Guns are now the leading cause of death for youth in the United States. Researcher from Mass General Brigham investigated whether firearm mortality rates among U.S. children ages 0-17 changed in the 13 years following a 2010 Supreme Court ruling that applied the Second Amendment to state and local governments. In states with the most permissive firearm laws, they found evidence of 6,029 more pediatric deaths due to firearms than would have been expected based on the existing demographic trends—and more than 1,400 excess ...

Landmark test for coeliac disease promises to take away the pain of diagnosis

2025-06-09
Imagine having to eat something that makes you sick – just to see what’s making you ill in the first place.  That’s the harsh reality of current diagnostic tests for coeliac disease, which require people to eat large amounts of gluten for weeks in order to get an accurate diagnosis. But this painful process could soon be a thing of the past, with WEHI researchers and industry partner Novoviah Pharmaceuticals developing a world-first blood test that can identify the condition in patients – even when they’re on gluten-free diets.   At a glance New clinical research published in the high-impact ...

A recipe for success: beefing up the taste of cultured meat with amino acids

2025-06-09
Tokyo, Japan – Across the world the demand for meat is growing, despite associated environmental and animal welfare costs. Although lab-grown – or cultured – meat could be part of the answer, scientists have yet to perfect one crucial detail: the taste. In an article to be published in Food Chemistry, researchers from the Institute of Industrial Science, The University of Tokyo, have measured and found a way to control the key amino acids responsible for flavor in a step toward making cultured meat taste just like the real thing. The push toward cultured meat has been adopted because conventional production is not a sustainable solution for ...

Protecting peppers from devastating viral diseases through gene pyramiding

2025-06-09
Even with today’s advanced agricultural technologies, plant diseases can still be extremely devastating to crops, causing billions of dollars in losses worldwide every year. Begomoviruses represent a prominent example of this threat—these whitefly-transmitted pathogens cause yellow leaf curl disease in peppers and can destroy up to 100% of fruit yield in affected fields across Asia, Africa, and the Americas. Breeding crops that are resistant to begomoviruses has long been the most effective and widely used strategy for preventing such massive losses. Though usually effective, this approach has serious limitations, especially when dealing with mixed infections. Scientists ...

Lizards of Madagascar

2025-06-09
Kyoto, Japan -- After the island of Madagascar drifted away from India 88 million years ago, isolating it from all other landmasses, its flora and fauna evolved in seclusion. As these transformed into plants and animals completely unique to their island, Madagascar became a biodiversity hotspot unlike anywhere else on Earth. An important facet of this biodiversity is an ecological process called endozoochory, which is when animals eat plant seeds and then poop them out somewhere else, aiding in the spread of the plants. Most research on endozoochory has focused on the roles of ...

Beyond the brain: how BCIs are rewiring medicine and redefining humanity

2025-06-09
Brain-computer interface (BCI) technology is opening an unprecedented chapter in human-machine integration by establishing direct communication between the brain and external devices. Once a science fiction concept, BCI is now reshaping the landscape of neurosurgery and neurorehabilitation. By decoding brain signals to restore lost motor, sensory, and language functions, BCIs offer new hope for individuals affected by paralysis, aphasia, and neurodegenerative diseases. But their impact extends well beyond the clinic—BCIs are poised to influence cognition, ethical governance, and national security. As this disruptive technology matures, ...

Fossilized dinosaur gut shows that sauropods barely chewed

2025-06-09
Plant fossils found in the abdomen of a sauropod support the long-standing hypothesis that these dinosaurs were herbivores, finds a study publishing June 9 in the Cell Press journal Current Biology. The dinosaur, which was alive an estimated 94 to 101 million years ago, ate a variety of plants and relied almost entirely on its gut microbes for digestion.   “No genuine sauropod gut contents had ever been found anywhere before, despite sauropods being known from fossils found on every continent and despite the group ...

School dental treatments stop kids’ tooth decay in its tracks

2025-06-09
Two topical treatments applied to kids’ cavities can stop the majority of them from progressing for years, according to a study led by NYU College of Dentistry and published in JAMA Network Open. Treating more than 10,000 cavities in New York City elementary school students, the researchers found that both atraumatic restorations (ART) and silver diamine fluoride (SDF) kept most dental decay from worsening, supporting the use of non-surgical approaches for managing cavities. Children miss an estimated 34 million hours of school each year due to emergency dental care. Bringing cavity prevention programs to schools can improve kids’ oral health and stave ...

How high is your dementia risk? It might depend on where you live

2025-06-09
In one of the largest and most comprehensive studies of its kind, a research team led at UC San Francisco has identified the regions where dementia occurs most often.  What They Discovered Using the Mid-Atlantic* as the basis for comparison, researchers found that dementia rates were 25% higher in the Southeast.** The Northwest*** and Rocky Mountains**** were both 23% higher, and the South***** was 18% higher. The Southwest, which includes California, was 13% higher; while the Northeast, which includes New York, was 7% higher.  These differences remained when researchers accounted for factors like age, ...

Firearm laws and pediatric mortality in the US

2025-06-09
About The Study: The results of this study demonstrate that permissive firearm laws contributed to thousands of excess firearm deaths among children living in states with permissive policies. Future work should focus on determining which types of laws conferred the most harm and which offered the most protection.  Corresponding Author: To contact the corresponding author, Jeremy Samuel Faust, MD, MS, email jsfaust@bwh.harvard.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2025.1363) Editor’s ...

Use of the 988 Suicide and Crisis Lifeline at national, regional, and state levels

2025-06-09
About The Study: The findings of this cross-sectional study suggest that although 988 has been contacted more than 16 million times since its launch in July 2022, there remains opportunity to increase 988 use. Corresponding Author: To contact the corresponding author, Jonathan Purtle, DrPH, MSc, email jonathan.purtle@nyu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.14323) Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, ...

Location of firearm suicides in the United States

2025-06-09
About The Study: This study found that nearly 1 in 5 firearm suicides in the U.S. occurred outside the home, highlighting the potential to enhance intervention strategies by extending them to broader community settings. Corresponding Author: To contact the corresponding author, Camerin A. Rencken, PhD, ScM, email crencken@uw.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.14423) Editor’s Note: Please see the article for additional information, including other authors, author contributions ...

Discovery suggests method to offset antibiotic-caused harm to infant immune systems

2025-06-09
In 2017, scientists at Cincinnati Children’s revealed that using antibiotics to protect newborns from dangerous infections often comes with a long-term consequence—a permanently underdeveloped immune system that can make children prone to poor outcomes from future lung infections. Now a study published June 9, 2025, in Cell, details the mechanisms behind antibiotic-related immune disruptions, which in turn suggests a way to reverse or minimize the risk. "These remarkable findings indicate that we might be able to protect at-risk infants through targeted supplementation," says senior author Hitesh Deshmukh, MD, PhD, a neonatologist with the Perinatal ...

SNU researchers develop world's first 3D microphone capable of position estimation with a single sensor

2025-06-09
Seoul National University College of Engineering announced that Professor Sung-Hoon Ahn's team from the Department of Mechanical Engineering has developed a novel auditory technology that allows the recognition of human positions using only a single microphone. This technology facilitates sound-based interaction between humans and robots, even in noisy factory environments.   The research team has successfully implemented the world's first 3D auditory sensor that "sees space with ears" through sound source localization and acoustic communication technologies.   The research findings were published on January 27 in the international ...

Cryo-EM structures of isovaleryl-CoA dehydrogenase offers new therapeutic strategies for inherited isovaleric acidemia

2025-06-09
Background IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects in IVD function lead to toxic accumulation of metabolites such as isovaleric acid, resulting in isovaleric acidemia (IVA)—a life-threatening autosomal recessive disorder characterized by vomiting, metabolic acidosis, and neurological damage. Although IVD gene mutations are known to cause IVA, the enzyme's structural dynamics and complex substrate-binding mechanisms have long hindered ...

JMIR Human Factors invites submission on human factors in health care

2025-06-09
(Toronto, June 9, 2025) JMIR Publications invites submissions to a new theme issue titled “Human Factors in Health Care: Education, Management, and Knowledge Translation” in its open access journal JMIR Human Factors. The premier, peer-reviewed journal is indexed in PubMed, PubMed Central (PMC), DOAJ, Sherpa/Romeo, Web of Science Core Collection: Emerging Sources Citation Index and Scopus. Education, awareness, and knowledge translation in the area of human factors are essential for optimizing the interaction between humans and ...

New book: Machine Learning in Quantum Sciences

2025-06-09
New book: Machine Learning in Quantum Sciences Cambridge University Press has published a new book Machine Learning in Quantum Science Machine Learning in Quantum Sciences co-authored by researchers from the University of Warsaw, offering both an introduction to machine learning and deep neural networks, and an overview of their applications in quantum physics and chemistry — from reinforcement learning for controlling quantum experiments to neural networks used as representations of many-body quantum states. The book appears at a time when artificial intelligence is becoming an increasingly recognized tool for scientific discovery — a development recently recognized ...

Partnership to support Indigenous researchers, ensure that cancer research reflects the needs of Indigenous groups and that it results in better care

2025-06-09
June 9, 2025, TORONTO – The Canadian Indigenous Nurses Association (CINA) and the Ontario Institute for Cancer Research (OICR) today announced a new partnership to include Indigenous priorities in cancer research, build capacity for research with and within First Nations, Inuit, and Métis (FNIM) communities, and increase research participation to ultimately reduce the burden of cancers within these populations. The organizations agree on the need to identify the unique cancer-related priorities of FNIM populations by supporting the training and advancement of Indigenous individuals working in cancer research and addressing ...

Mount Sinai Health System earns several prestigious national honors for environmental excellence

2025-06-09
New York, NY — (June 9, 2025) — Mount Sinai Health System has been recognized with three top honors by Practice Greenhealth, the nation’s leading organization dedicated to environmental sustainability in health care. The awards celebrate the significant progress that Mount Sinai has made in integrating environmentally responsible practices across its hospitals and facilities—a program known as Mount Sinai Green that reflects a systemwide commitment to a healthier planet and patients. “Mount Sinai Health System is committed to helping create a cleaner tomorrow by elevating our environmental stewardship and strengthening our organizational ...

Screen time and emotional problems in kids: A vicious circle?

2025-06-09
Spending too much time on screens may cause emotional and behavioral problems in children – and those problems can lead to even more screen use, according to research published by the American Psychological Association. Conducted by an international team of researchers, the study systematically reviewed and meta-analyzed 117 studies, encompassing data from over 292,000 children worldwide. The findings were published in the journal Psychological Bulletin. “Children are spending more and ...

UC San Diego researchers find evidence of accelerated aging in children with multiple sclerosis

2025-06-09
Researchers from University of California San Diego School of Medicine have discovered that children living with multiple sclerosis (MS) show signs of accelerated biological aging, even in their teenage years. The research published online recently in Neurology®, the medical journal of the American Academy of Neurology, is the first to examine whether MS causes early aging in a pediatric population — offering new insight into the disease and its long-term progression. “We found evidence that children living with MS experience accelerated biological aging,” said ...

Out of the string theory swampland

2025-06-09
String theory has long been touted as physicists’ best candidate for describing the fundamental nature of the universe, with elementary particles and forces described as vibrations of tiny threads of energy. But in the early 21st century, it was realized that most of the versions of reality described by string theory’s equations cannot match up with observations of our own universe. In particular, conventional string theory’s predictions are incompatible with the observation of dark energy, which appears to be causing ...

Cancer screenings continue years after guidelines change to limit unnecessary tests, study finds

2025-06-09
Stopping the widespread use of unnecessary, potentially even harmful, cancer screenings can take up to 13 years and potentially even longer after new guidelines are put in place, according to a new study. Those unnecessary screenings open up patients to potential overdiagnosis, pain and excessive treatment, while costing more money and leading to anxiety and fear. “Excessive screening opens the door for a lot of negative consequences,” said Jennifer LeLaurin, Ph.D., an assistant professor of health outcomes and biomedical informatics at the University of Florida and lead author of the new study. “These ...

Mood disorders in late-life may be early warning signs for dementia

2025-06-09
Depression and bipolar disorder of late onset may represent more than just mental health conditions. Growing evidence suggests these late-life mood disorders (LLMDs) could be not merely risk factors, but rather early warning signs of neurodegenerative diseases like dementia, even when they appear years before memory loss or other cognitive symptoms become apparent. Unfortunately, scientists have struggled to understand the connection between LLMDs and developing dementia at the biological level. While previous research suggested connections between specific disorders like late-life depression and Alzheimer’s disease, the specific neurological mechanisms involved remain mostly unclear. ...

Could electric fields supercharge immune attack on the deadliest form of brain cancer?

2025-06-09
LOS ANGELES — A new study led by Keck Medicine of USC researchers may have uncovered an effective combination therapy for glioblastoma, a brain tumor diagnosis with few available effective treatments. According to the National Brain Tumor Society, the average survival for patients diagnosed with glioblastoma is eight months. The study finds that using Tumor Treating Fields therapy (TTFields), which delivers targeted waves of electric fields directly into tumors to stop their growth and signal the body’s immune system to attack cancerous tumor cells, may extend survival among patients with glioblastoma, when combined with immunotherapy (pembrolizumab) ...
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