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Science30 Oct 2025

UAlbany researcher partners on $1.2 million NSF grant to explore tropical monsoon rainfall patterns

ALBANY, N.Y. (Oct. 30, 2025) — A University at Albany researcher is teaming up with scientists from five institutions on a $1.2 million National Science Foundation project to better understand monsoon rainfall patterns across Asia, Indonesia and Australia over the last millennium — and how they might look in the future under a changing climate. For decades, scientists have studied natural records around the Eastern Hemisphere tropics to reconstruct past changes in monsoon rainfall. These records, which include stalagmites, corals, ...

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Science30 Oct 2025

Checkup time for Fido? Wait might be longer in the country

COLUMBUS, Ohio – Most people can get their pets in for veterinary visits relatively quickly, but access to care could use improvement in rural areas, suggests a recent study. “Access to veterinary care appears to be generally pretty good and the wait times aren’t too long, particularly if you compare it to how long people often have to wait to establish primary care, but there’s clearly room for improvement in less populated areas,” said Simon Haeder, the study’s lead author and an associate professor in Ohio State’s College of Public Health. The research appears in ...

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Medicine30 Oct 2025

Genetic variation impact scores: A new tool for earlier heart disease detection

An international research consortium co-led by scientists from Vanderbilt University Medical Center, the University of Toronto and University of Pittsburgh has mapped the functional impact of more than 17,000 variants in a major gene associated with the development of premature atherosclerotic heart disease. The study, reported Oct. 30 in the journal Science, will go a long way to improving the early diagnosis and treatment of familial hypercholesterolemia (FH), a common genetic driver of cardiovascular ...

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Medicine30 Oct 2025

The Lundquist Institute awarded $9 million to launch Community Center of Excellence for Regenerative Medicine

Christina Wang, MD, and Lynda Polgreen, MD, MS, investigators at The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, have been awarded $9 million from the California Institute for Regenerative Medicine (CIRM) to establish the South Los Angeles Community Center of Excellence for Regenerative Medicine (SoLA-CCERM) at The Lundquist Institute. SoLA-CCERM is a pioneering initiative designed to expand access to cutting-edge regenerative therapies and create a robust pipeline of skilled healthcare ...

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Technology30 Oct 2025

'Really bizarre and exciting': The quantum oscillations are coming from inside

As someone who studies materials, Lu Li knows people want to hear about the exciting new applications and technologies his discoveries could enable. Sometimes, though, what he finds is just too weird or extreme to have any immediate use. Working with an international team of researchers, Li has made one of those latter types of discoveries, which the group detailed in the journal Physical Review Letters. "I would love to claim that there's a great application, but my work keeps pushing that dream further away," ...

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Technology30 Oct 2025

Is AI becoming selfish?

New research from Carnegie Mellon University's School of Computer Science shows that the smarter the artificial intelligence system, the more selfish it will act. Researchers in the Human-Computer Interaction Institute (HCII) found that large language models (LLMs) that can reason possess selfish tendencies, do not cooperate well with others and can be a negative influence on a group. In other words, the stronger an LLM's reasoning skills, the less it cooperates. As humans use AI to resolve disputes between friends, provide marital guidance and answer other social questions, models that can reason might ...

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Energy30 Oct 2025

New molten salt method gives old lithium batteries a second life

As electric vehicles become more common, the number of used lithium-ion batteries is soaring. These batteries contain valuable metals such as nickel, cobalt, and lithium, but current recycling methods often destroy the complex crystal structure that makes them work efficiently. Now, researchers from Huazhong University of Science and Technology have developed a new molten salt technique that restores the structure and performance of used high-nickel cathode materials, offering a greener and more efficient route to battery recycling. The study, published in Energy & Environment Nexus, introduces a direct regeneration strategy ...

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Medicine30 Oct 2025

Leg, foot amputations increased 65% in Illinois hospitals between 2016-2023

Men, Black Americans, those living in areas with low socioeconomic status more affected The Illinois data from a diverse population (ethnic/racial, rural/metropolitan) likely reflects national amputation trends ‘Unless we make changes in how we care for marginalized communities, I don’t anticipate this getting better’ CHICAGO --- Rates of leg and foot amputations in Illinois hospitals increased 65% between 2016 and 2023, reports a new Northwestern Medicine study. Men, Black patients, and those living in areas with low socioeconomic status were disproportionally affected, the study found. The dramatic spike is ...

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Medicine30 Oct 2025

Moffitt studies uncover complementary strategies to overcome resistance to KRAS G12Cinhibitors in lung cancer

TAMPA, Fla. (Oct. 30, 2025) — Two companion studies published in Cancer Research from scientists at Moffitt Cancer Center identify distinct but complementary approaches to overcoming drug resistance in KRAS G12C–mutant non-small cell lung cancer. RAS genes produce proteins that act like on/off switches for cell growth. In healthy cells, this helps regulate normal tissue function. But when RAS is mutated, especially in cancers like non-small cell lung cancer, it can become stuck in the ...

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Science30 Oct 2025

National summit of experts charts unprecedented roadmap to reduce harms from firearms in new ways

A safer America will require bold investment in discovering, implementing, and scaling solutions that reduce firearm harms—especially those that center the people and communities most affected. That was the clear message from the JAMA Summit on Firearm Violence, which convened 60 leaders from across the nation to chart a roadmap toward reducing firearm violence, injuries, and deaths in the United States to record lows by 2040. The full report findings of the 2025 Summit are published in JAMA this month. Over two days, experts from public health, medicine, law, economics, and industry participated in sessions focused on: Achieving the safest ...

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Medicine30 Oct 2025

Global environmental DNA (eDNA) surveys significantly expand known geographic and ecological niche ranges of marine fish, highlighting current biases in conservation and ecological modeling

Global environmental DNA (eDNA) surveys significantly expand known geographic and ecological niche ranges of marine fish, highlighting current biases in conservation and ecological modeling In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology: https://plos.io/42mNz7A Article title: eDNA surveys substantially expand known geographic and ecological niche boundaries of marine fishes Author countries: France, Switzerland, Tanzania, Indonesia Funding: see manuscript END ...

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Medicine30 Oct 2025

Hundreds of animal studies on brain damage after stroke flagged for problematic images

A new study has identified over 240 scientific publications on animal models of hemorrhagic stroke that contain potentially problematic images, thereby raising concerns about the trustworthiness of the body of literature this field. The findings come from a team led by René Aquarius and Kim Wever at Radboud university medical center in the Netherlands, and are published October 30th in the open-access journal PLOS Biology. Researchers often use images in their publications to provide evidence of whether a treatment works, for example, by showing the ...

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Medicine30 Oct 2025

Prize winner’s research reveals how complex neural circuits are correctly wired during brain development

Cheng Lyu is the winner of the 2025 Eppendorf & Science Prize for Neurobiology for her work in understanding how neural circuits assemble with such remarkable precision during development. Neural circuit assembly is a daunting challenge: young neurons must form specific connections with their correct synaptic partner among billions of others. How does the developing brain achieve such exquisite precision? What happens when it fails? To explore this unknown, Cheng Lyu and her research team turned to the fruit fly Drosophila, ...

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Earth Science30 Oct 2025

Supershear rupture sustained in thick fault zone during 2025 Mandalay earthquake, study in research package shows

A massive March 2025 earthquake in Myanmar tore through nearly 500 kilometers of the Sagaing Fault at extremely high speeds. In a new study – part of a package of four research articles on seismic activity in Myanmar – researchers show that an unusually thick, low-velocity fault zone acted like a high-speed corridor, driving one of the fastest and longest continental ruptures ever recorded. The largest earthquakes that occur within continental crusts can rupture faults extending for hundreds of kilometers and pose significant seismic threats. Many of these powerful events evolve into supershear ruptures – earthquakes in which the rupture front ...

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Medicine30 Oct 2025

Study reveals how brain cell networks stabilize memory formation

Newly decoded brain circuits make memories more stable as part of learning, according to a new study led by NYU Langone Health researchers. Published online in Science on Oct. 30, the study shows that activity in signaling pathways connecting two brain regions, the entorhinal cortex and the CA3 region of the hippocampus, help mice encode in brain circuitry maps of places. The entorhinal/hippocampal circuit is known from past studies to be crucial for both memory formation, and the recalling of memories by completing patterns from partial cues. Reliable recall requires that hippocampal place maps remain stable, withstanding to some degree changes in the environment. Problems ...

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Science30 Oct 2025

CTE: More than just head trauma, suggests new study

Chronic traumatic encephalopathy (CTE) – most often found in athletes playing contact sports – is known to share similarities with Alzheimer’s disease (AD), namely the buildup of a protein called tau in the brain. New research published today in Science finds even more commonalities between the two at the genetic level, showing CTE (like AD) is linked to damage to the genome and not just caused by repeated head impact (RHI). The research team, a collaboration between Boston Children’s Hospital, Mass General Brigham, and Boston University, used single-cell genomic sequencing to identify somatic genetic mutations (changes in DNA that ...

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Medicine30 Oct 2025

New psychology study suggests chimpanzees might be rational thinkers

Chimpanzees may have more in common with human thinkers than previously thought. A new study published in Science by researchers provides evidence that chimpanzees can rationally revise their beliefs when presented with new information. The study, titled “Chimpanzees rationally revise their beliefs,” was conducted by a large research team that included UC Berkeley Psychology Postdoctoral Researcher Emily Sanford, UC Berkeley Psychology Professor Jan Engelmann and Utrecht University Psychology Professor Hanna Schleihauf. Their findings showed that chimpanzees — like humans ...

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Medicine30 Oct 2025

Study links genetic variants to higher 'bad' cholesterol and heart attack risk

PITTSBURGH, Oct. 30, 2025 – An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource to identify those with a genetic risk for elevated ‘bad’ cholesterol -- a major contributor to heart disease. Published today in Science, this resource can assist clinicians in predicting patient risk for heart attacks and strokes, allowing time for prevention and early treatment. Heart disease remains the leading cause of death in the United States, claiming nearly 700,000 ...

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Earth Science30 Oct 2025

Myanmar fault had ideal geometry to produce 2025 supershear earthquake

A UCLA-led team of scientists has uncovered how the devastating magnitude 7.7 earthquake that struck Myanmar in March 2025 produced one of the longest and fastest-moving ruptures ever recorded on land. The study, published in Science, shows that the earthquake ruptured about 530 kilometers of the Sagaing Fault, with a 450-kilometer segment racing faster than the speed of seismic shear waves—a rare phenomenon known as a supershear rupture. These “Mach-like” ruptures generate shock waves that can greatly amplify ground shaking and damage. “Supershear earthquakes are like breaking the sound barrier, but in rock,” said Lingsen Meng, a professor of ...

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Science30 Oct 2025

Breakthrough in BRCA2 research: a novel mechanism behind chemoresistance discovered

One of the biggest challenges in cancer treatment is chemoresistance: tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often limited. The research team led by Arnab Ray Chaudhuri has now uncovered a mechanism by which BRCA2-deficient tumors develop this resistance. The proteins BRCA2 and FIGNL1 appear to have a different function than previously assumed. “These findings change the paradigm of thought,” says Ray Chaudhuri. The team also ...

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Medicine30 Oct 2025

New funding for health economics research on substance use disorder treatments

A team led by Weill Cornell Medicine and University of Miami’s Miller School of Medicine investigators has been awarded a five-year, $4 million grant from the National Institute on Drug Abuse (NIDA) for health economics research. The team will study the economics of substance use disorder treatments and overdose prevention strategies for individuals who are incarcerated or otherwise involved in the United States’ criminal legal system. Interventions for people with substance use disorders are often inadequate in the criminal-legal ...

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Medicine30 Oct 2025

Tying protein to fraying DNA solves mystery of illness for patients around the world

MADISON — New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining stability in our chromosomes may be responsible for serious — and sometimes deadly — diseases. Their findings, published today in Science, could provide patients and their doctors with new protein mutations to test for certain cancers and bone marrow diseases. Our chromosomes (bundles of proteins and DNA that store all our genetic information), are protected from degradation by telomeres — the protective caps at the ends of chromosomes made from repetitive DNA ...

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Science30 Oct 2025

MD Anderson shares latest research breakthroughs

Researchers characterize distinct immune environments in lymphoma, providing a new framework to engage the immune system in treating the disease Study finds U.S. adults have widespread misperceptions of the cancer risks of alcohol Scientists discover new target for pain hypersensitivity Early clinical studies show encouraging results in kidney and prostate cancer HOUSTON, OCTOBER 30, 2025 ― At The University of Texas MD Anderson Cancer Center, research breakthroughs are made possible through seamless collaboration between ...

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Medicine30 Oct 2025

19 women’s college basketball coaches join forces to improve women’s cardiovascular health

DALLAS, Oct. 30, 2025 — Both on the court and off, cardiovascular disease is the leading killer of women in the United States, taking the lives of more than 440,000 women each year, according to the American Heart Association, a relentless force changing the future of health for everyone everywhere. The Association’s Go Red for Women® movement is working to raise awareness, improve education and inspire action to help women better understand and learn how to prevent their number one health threat. For the first time, 19 National Collegiate Athletic Association (NCAA) women’s ...

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Science30 Oct 2025

Palaeontology: How ammolite gemstones get their vivid colours

The origins of vivid colours within the gemstone ammolite — a rare type of brightly coloured fossilised ammonite shell — are reported in research published in Scientific Reports. The colours of ammolite occur within a preserved layer of nacre — also known as mother-of-pearl — which consists of layered plates of the mineral aragonite and a small amount of organic material such as proteins. Although it is thought that the colours of ammolite arise from the interaction of light with these layers, the origins of these colours have not been evaluated experimentally. Hiroaki ...

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