Shared synaptic mechanism for Alzheimer's and Parkinson’s disease unlocks new treatment possibilities
Parkinson’s and Alzheimer’s diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the Okinawa Institute of Science and Technology (OIST) suggests a shared molecular cascade between the two diseases which causes synaptic dysfunctions, advancing our understanding of how their symptoms are produced.
The researchers investigated how brain cell communication across synapses is disrupted by disease-related protein buildup. They found a pathway that interferes with synaptic ...