The bacteria Acinetobacter baumannii (A. baumannii) is a haunting presence in many hospitals in the United States, where more than one in 100 patients are treated for A. baumannii infections. This species of bacteria is known for its dynamic genome and ability to gain antibiotic resistance. “This is a deadly pathogen that is notorious for its resistance to traditional drugs,” said Andrei Osterman, PhD, a professor in the Center for Data Science and Artificial Intelligence at Sanford Burnham Prebys Medical Discovery Institute and vice dean and associate dean of Curriculum in the Graduate School of Biomedical Sciences. Prior ...

Spatial maps of lung precancer and cancer cells at different points in development advance understanding of the earliest stages of lung cancer Findings highlight inflammation as a driver of lung tumor initiation Targeting inflammation could be a potential therapeutic strategy to intercept lung cancer and improve patient outcomes By creating high-resolution cellular and molecular visual maps of lung cancer before and during development, researchers at The University of Texas MD Anderson Cancer Center have discovered that the earliest stages of lung cancer may be driven by inflammation, suggesting that ...

A widely prescribed diabetes drug may be sabotaging one of the most trusted strategies for preventing the disease: exercise. That is the conclusion of a Rutgers-led study published in The Journal of Clinical Endocrinology & Metabolism, which found that metformin blunts critical improvements in blood vessel function, fitness and blood sugar control that normally come from working out. Since 2006, doctors have been advised to tell patients with high blood sugar to take metformin while engaging in exercise. Two proven therapies should deliver better results together, they reasoned. But Rutgers researchers ...

Tambet Teesalu, University of Tartu Professor of Nanomedicine, has been awarded an ERC Synergy Grant to study the blood-nerve barrier – the interface between blood vessels and nerve cells – in search of solutions to shortcomings in pain treatment.  Teesalu’s research group, in collaboration with colleagues from the United Kingdom, Italy and France, will focus closely on the peripheral nervous system to create a detailed molecular and spatial map of the blood-nerve barrier and therapeutic approaches that could influence ...

A new dataset released via the Human Climate Horizons (HCH) data platform by the United Nations Development Programme (UNDP) Human Development Report Office, in collaboration with the Climate Impact Lab, warns that climate change is set to dramatically undermine agricultural productivity, with some of the greatest risks concentrated in countries least able to adapt. The dataset, sourced from a Nature study released in June by the Climate Impact Lab and collaborating institutions [press release], finds every additional degree Celsius of global warming ...

Quantum computers are powerful, lightning-fast and notoriously difficult to connect to one another over long distances.  Previously, the maximum distance two quantum computers could connect through a fiber cable was a few kilometers. This means that, even if fiber cable were run between them, quantum computers in the University of Chicago’s South Side campus and downtown Chicago’s Willis Tower would be too far apart to communicate with each other.  Research published today in Nature ...

NEW ORLEANS (Nov. 6, 2025) —Fewer than half of young adults with severely high low-density lipoprotein (LDL-C), or “bad” cholesterol, levels start taking a statin within five years of first high LDL-C measurement, according to a study published in JACC, the flagship journal of the American College of Cardiology, and presented at the American Heart Association’s 2025 Scientific Sessions. The 2018 ACC/AHA Cholesterol Guideline recommends a statin in patients with LDL-C over 190 mg/dL and these ...

HERSHEY, Pa. — In June 2022, the U.S. Supreme Court’s decision in Dobbs v. Jackson Women’s Health Organization ended the federal constitutional right to abortion and returned authority to individual states to regulate abortion. A new study from researchers at Penn State, Albany Medical Center, University of South Florida and University of Tennessee Medical Center revealed that the change in abortion policies appears to have a trickle-down effect, influencing reproductive health and family planning decisions. The research team found that the number of women undergoing tubal ligations — ...

Current U.S. immigration enforcement and deportation policies are producing widespread harm to physical and mental health, with family separation and the specters of fear and intimidation affecting the well-being of immigrant and non-immigrant communities. That’s the warning from several longtime public health researchers, who also outline proven community and policy actions that could reduce harm and strengthen health in communities across the nation. Professors from five prestigious U.S. research universities called for health care professionals and researchers to advocate for the end of deportations and restrictive immigration policies. Their insights appear in the ...

Toronto, ON, November 6, 2025 – Adults diagnosed with a concussion may be at about 50 per cent higher risk of a subsequent traffic crash, finds a new study from researchers at ICES and Sunnybrook Research Institute. Concussions can temporarily affect brain function, with symptoms including insomnia, dizziness, depression, brain fog, and slowed reaction times that can linger for weeks. These symptoms could alter driving skills and increase the risk of a motor vehicle accident. “I worry ...

When Linda Moslow, A16P, A18P, entered perimenopause in her early 40s, she was blindsided. “I’d always been healthy and grounded in wellness,” she says. “Suddenly, I couldn’t recognize myself.” The months of anxiety, sleeplessness, and confusion that followed left her feeling unmoored until she found a team of doctors who helped her understand what was happening. The experience was both personal and galvanizing. Realizing that millions of women lacked the support she’d been lucky to find, Moslow started ...

Plant biologists have developed a method for growing transgenic and gene-edited plants that cuts the slow and expensive process down from months to weeks. Publishing November 6 in the Cell Press journal Molecular Plant, the method takes advantage of plants’ natural ability to regenerate after being wounded or pruned. By injecting bacteria carrying genetic instructions for wound healing and regeneration into a pruned plant’s wound site, the researchers triggered the plant to grow new shoots, some of which were transgenic and gene edited. The method shows potential even in species that ...

Type 1 diabetes is caused by an insufficient production of the hormone insulin by cells in the pancreas called beta cells and estimated to affect 9.5 million people worldwide. Low insulin levels allow glucose levels to remain elevated, which in the long term can damage organs such as the kidneys, the eyes, and the cardiovascular system. People with diabetes require lifelong monitoring of blood sugar levels coupled with insulin injections to keep blood sugar levels at a stable, healthy level. A potential new treatment option ...

A new high resolution digital dataset and map — named Itiner-e — of roads throughout the Roman Empire around the year 150 CE is presented in research published in Scientific Data. The findings increase the known length of the Empire’s road system by over 100,000 kilometres. At its height in the second century CE, the Roman Empire included over 55 million people and stretched from modern day Britain to Egypt and Syria. Although a network of roads throughout the Empire facilitated ...

About The Study: In this large, diverse sample of first-time mothers in the U.S., 1 in 27 participants reported feeding their infants shared human milk. Prior work indicates that families engage in many, but not all, recommended milk sharing risk mitigation measures and fear disclosing their milk sharing to practitioners. Given the prevalence in this study, pediatric practitioners should be aware that milk sharing occurs across demographics; they can counsel families considering or using shared milk on risks and risk-reduction strategies ...

Over-the-counter pain medications work as well or better than opioids after wisdom tooth extraction for both men and women, according to a Rutgers Health-led follow-up to a landmark paper on comparative pain relief. That first paper on the collective experience of more than 1,800 trial patients found that the combination of ibuprofen and acetaminophen provided better pain relief than hydrocodone with acetaminophen for the first two days after surgery and greater satisfaction over the post-operative period. The new subgroup analysis, published in JAMA Network Open, demonstrated that the results held for both ...

About The Study: The results of this study of pharmacies in British Columbia, Canada, suggest that when medication abortion is available as a routine health service and mifepristone is regulated as a routine prescription, pharmacists play a key role in providing geographically distributed access to medication abortion. These findings may inform policy and initiatives to enhance pharmacist referral networks and improve mifepristone access, as well as service planning for international jurisdictions considering a similar medication abortion ...

Most pharmacies in British Columbia can provide the abortion pill mifepristone within days, but uneven access still leaves some women facing barriers to this time-sensitive medication, according to new research.  The study, published Nov. 6 in JAMA Network Open, offers the first province-wide look at pharmacy-level access to mifepristone in B.C.  Mifepristone is used for medical abortions and can be prescribed across Canada by any physician or nurse practitioner and filled at community pharmacies. Initially available only from pharmacists who had completed a training module and pharmacies registered with the manufacturer, Health Canada removed these requirements ...

Researchers from University of Jyväskylä have found that personalized interactive music systems – smart technologies that adapt rhythm and tempo to users’ movements – can make exercise more enjoyable and help people stay active longer. These systems, known as PIMSs, use real-time data from wearables and smartphones to adjust musical features such as beat, tempo, and style to match the user’s pace – whether walking, cycling or lifting weights. For example, when the systems detects you speeding up, it raises the music’s tempo to match your ...

Researchers at the University of California San Diego have found that an intensive retreat combining multiple mind-body techniques, including meditation and healing practices, produced rapid and wide-ranging changes in brain function and blood biology. The researchers found that the retreat engaged natural physiological pathways promoting neuroplasticity, metabolism, immunity and pain relief. The findings, published in Communications Biology, provide insights into how consciousness and psychological practices can enhance physical health. Meditation and other mind-body practices ...

Mark Zuckerberg and Priscilla Chan today announced the launch of a first-of-its-kind initiative combining frontier artificial intelligence and frontier biology to dramatically accelerate scientific progress toward understanding and addressing human disease. Since its founding in 2016, Biohub’s multidisciplinary teams of scientists and engineers have developed groundbreaking technologies to observe, measure, and program biology at the cellular level. The organization has built the largest single-cell datasets and established large-scale compute ...

The nonsteroidal mineralocorticoid receptor antagonist finerenone has been shown to reduce the risks of major clinical kidney and cardiovascular outcomes in individuals with chronic kidney disease (CKD) and type 2 diabetes. In the phase 3 FINE-ONE trial, investigators assessed the efficacy and safety of finerenone in people with CKD and type 1 diabetes, a patient population that has not had new therapies in the last 30 years. FINE-ONE randomized 242 patients to finerenone or placebo. “The study used albuminuria change over 6 months of treatment as endpoint and bridging biomarker to translate evidence of long-term kidney protective effects from type 2 diabetes and CKD ...

The drug finerenone has a positive effect on patients with type 1 diabetes and chronic kidney disease. The drug reduces the amount of proteins excreted in the urine of these patients. This reduction indicates that the degree of kidney damage is reduced and that the drug has a protective effect on kidney function. Clinical pharmacologist Hiddo Lambers Heerspink of the UMCG led a large international study into the effect of this drug. He will present the initial results of this study at the American Society of Nephrology conference in Houston, where he will present the results during the plenary ...

Election researchers from across Europe have looked at how populist parties profile themselves on Facebook. Their findings are quite clear. "Populist parties much more often use controversial, divisive issues when they want to show themselves to potential voters," says Melanie Magin, a professor of media sociology at the Norwegian University of Science and Technology (NTNU's) Department of Sociology and Political Science. Magin and her fellow researchers believe this is probably quite deliberate in order to get the debate into a track that these parties believe they benefit from. The elections to the European Parliament ...

The American Association for Cancer Research (AACR) has endorsed a federal policy that would make cigarettes far less addictive. The proposed policy by the Food and Drug Administration (FDA) sets a maximum nicotine product standard, limiting nicotine levels in combustible cigarettes and related tobacco products to 0.7 milligrams per gram (mg/g) – about 95% less than what is currently allowed. That reduction would make cigarettes minimally or nonaddictive, striking at the chemical that keeps people hooked. The AACR policy statement is published in Clinical Cancer Research. Leading the policy statement ...