A long-term follow-up study from a consortium of six European countries, coordinated by the department of Surgery of the University Medical Center Groningen (UMCG) shows that, even 10 years after transplantation, deceased-donor kidneys performed better when they were preserved on a machine between organ retrieval and transplantation than those that underwent static cold storage before implantation. These remarkable results were published in the New England Journal of Medicine on November 6, 2025.  Machine Preservation Trial Corresponding author Cyril Moers, scientist and transplant surgeon at the UMCG, explains: “These ...

EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, NOVEMBER 5, 2025 Highlights: Three or more drinks a day? Your brain may pay. A new study links heavy drinking to having a bleeding stroke at a younger age when compared to non-heavy drinking. Heavy drinkers had bleeding strokes 11 years earlier than non-heavy drinkers. They also had 70% larger bleeds and nearly twice the risk of deep brain bleeds. Heavy drinkers were three times more likely to show brain aging and white matter damage. MINNEAPOLIS — People who drink heavily may have bleeding strokes a decade earlier than people who are not heavy drinkers, ...

A new study by investigators from Mass General Brigham suggests that heavy alcohol use may lead to more severe brain bleeds and cause long-term brain vessel damage at a younger age. The team’s results, based on patients treated for brain bleeds at Massachusetts General Hospital, are published online in Neurology, the medical journal of the American Academy of Neurology. “The brain bleed is one of the most lethal and disabling conditions known to human beings,” said corresponding author Edip Gurol, MD, a clinician investigator in the Mass General Brigham Department of Neurology. “They come on suddenly, ...

EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, NOVEMBER 5, 2025 MINNEAPOLIS — Older adults who have a heart attack may be more likely to develop epilepsy later in life, according to a study published November 5, 2025 in Neurology®, the medical journal of the American Academy of Neurology. While the study shows a link between these conditions, it does not prove cause and effect. “In middle-aged and older adults, vascular disease can block, weaken or narrow blood vessels, and it often affects multiple parts of the body at once,” ...

A new study from researchers at the Johns Hopkins Bloomberg School of Public Health finds that common fungal species may be adapting to higher temperatures in warmer sites within cities compared to cooler sites in the same city. The findings could signify that urban fungi could one day evolve into disease-causing pathogens. The researchers note that this is a proof-of-principle study, designed to investigate whether fungal species may adapt differently across sites within the same city. While the new findings suggest that they might, the researchers emphasize that more studies, with more samples in different cities, are needed. Fungi ...

FOR IMMEDIATE RELEASE Wednesday, November 5, 2025 Contact: Jillian McKoy, jpmckoy@bu.edu  Michael Saunders, msaunder@bu.edu ##  The rise in virtual research since the COVID-19 pandemic has created opportunities for researchers to expand and diversify clinical trials, but it has also opened up avenues for fraudulent participation in these studies. A new study led by Boston University School of Public Health (BUSPH) researchers directed by Michael Stein, chair and professor of the Department of Health Law, Policy & Management ...

Parents' attachment style may be linked with risk of parental burnout, especially when associated with difficulty in understanding and identifying their emotions Article URL: http://plos.io/3Lv62sL Article title: Alexithymia and attachment dimensions in relation to parental burnout: A structural equation modelling approach Author countries: Poland Funding: The author(s) received no specific funding for this work. END ...

Abnormal repetitive behaviors in mice are strongly linked to multiple biomarkers of oxidative stress, which occurs when antioxidants cannot counteract the effects of harmful molecules in the body, according to a study published November 5, 2025, in the open-access journal PLOS One by Kendall Coden and Dr. Joseph Garner of Stanford University, U.S. However, more research is needed to test whether antioxidants can prevent or treat these behaviors. Stereotypies are abnormal, repetitive, and seemingly goal-less behaviors that are prevalent within the animal kingdom. They have been documented in nearly every captive mammal and bird species, including laboratory ...

Belonging to more than one marginalized group can make building and maintaining social connections significantly harder, often in ways that go far beyond a simple sum of disadvantages. A new study shows how inequalities in social ties don’t just add up – they can amplify one another. Why do some people have more friendships, more support, and more opportunities – while others seem to have far fewer? Is it simply a matter of personal choices, or do structural patterns play a deeper role? For individuals who belong to a disadvantaged social group, forming connections tends to be more ...

From stirring milk in your coffee to fearsome typhoon gales, rotating turbulent flows are everywhere. Yet, these spinning currents are as scientifically complex as they are banal. Describing, modelling, and predicting turbulent flows have important implications across many fields, from weather forecasting to studying the formation of planets in the accretion disk of nascent stars. Two formulations are at the heart of the study of turbulence: Kolmogorov’s universal framework for small-scale turbulence, which describes how energy propagates and dissipates through ...

Aggression and self-harm often co-occur in individuals with a history of early-life trauma—a connection that has largely been documented by self-reporting in research and clinical settings. Adding to this connection, individuals treated for self-inflicted injuries are five times more likely to engage in excessive aggression. What’s happening in the brain to tie these two behaviors together?  A new study by Sora Shin, an assistant professor in the Fralin Biomedical Research Institute at VTC’s Center for Neurobiology Research, has identified a brain circuit that changes after trauma. The study was published Nov. 5 in Science ...

Article Summary Certain immune cells help breast cancer resist hormone therapy. Sylvester researchers studied how blocking those cells with a new drug combo may help. The approach could lead to better treatment options for tough-to-treat hormone therapy resistant breast cancer cases. MIAMI, FLORIDA (EMBARGOED UNTIL NOV 5, 2025, AT 2:00 P.M. ET) – In preclinical studies, researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine,  have tested a new combination ...

A collaborative research team has discovered that the Southern Ocean releases substantially more carbon dioxide (CO2) during the dark austral winter than previously thought. Their new study reveals that this winter outgassing has been underestimated by up to 40%. The team comprises researchers from the Second Institute of Oceanography, Ministry of Natural Resources (SIO-MNR), and the Nanjing Institute of Geography and Limnology (NIGLAS) of the Chinese Academy of Sciences. Their findings were published in Science Advances on ...

In the summer of 2020, an international team led by a University of Arizona archaeologist reported the discovery of the largest monumental construction known today in the Maya area in the state of Tabasco, near Mexico's southeastern border.  The monument, found at a site called Aguada Fénix, measures nearly a mile long and a quarter-mile wide, ranges from 30 to 50 feet high and dates to 1,000 B.C. In the five years since that discovery, the team, led by Regents Professor of anthropology Takeshi Inomata and Fred A. Reicker Distinguished Professor of anthropology Daniela Triadan, has pieced together evidence about Aguada ...

CAMBRIDGE, MA -- A large-scale screen of tuberculosis proteins has revealed several possible antigens that could be developed as a new vaccine for TB, the world’s deadliest infectious disease. In the new study, a team of MIT biological engineers was able to identify a handful of immunogenic peptides, out of more than 4,000 bacterial proteins, that appear to stimulate a strong response from a type of T cells responsible for orchestrating immune cells’ response to infection. There is currently only ...

HOUSTON – (Nov. 5, 2025) – Rice University applied physicist Junichiro Kono has been awarded the American Physical Society’s 2026 Frank Isakson Prize for Optical Effects in Solids. The biennial prize recognizes outstanding optical research that leads to breakthroughs in the condensed matter sciences. Kono is being honored “for pioneering contributions to optical physics, light-condensed matter interactions and photonic applications of nanosystems, including artificial quantum structures and carbon-based nanomaterials.” Kono’s ...

LA JOLLA, CA—During the first weeks of pregnancy, the developing placenta in a mother’s womb undergoes a dramatic change. Individual cells  merge, forming a continuous barrier that will spend the next nine months ferrying oxygen and nutrients to the growing fetus while keeping the mother's immune system at bay. When this structure fails to form properly, pregnancies are at higher risk of complications, including preeclampsia and restricted fetal growth. Now, scientists at Scripps Research have identified a key player in the placenta’s transformation—a molecule called galectin-3 that binds to sugar molecules on specific ...

Geneva, 5 November 2025 – ​​​​The International Telecommunication Union (ITU) will join the global community at COP30 in Belém, Brazil, to advance the Green Digital Action initiative – a platform driving collective progress toward a sustainable digital future.​ The ITU delegation, led by Deputy Secretary-General Tomas Lamanauskas, will work with governments, private-sector leaders, and civil society to leverage digital transformation as a catalyst for climate solutions and work toward a sustainable digital sector. Why digital technologies at COP30 matter As global demand for technology ...

Words matter — but your hands might matter more, according to a new UBC study which found that purposeful hand gestures can make speakers appear more competent and persuasive. The Sauder School of Business research, analyzed 2,184 TED Talks using AI and automated video analysis. Researchers isolated more than 200,000 hand gestures into 10-second clips and compared them against audience engagement metrics, such as ‘likes’ on social media while controlling for factors like gender, occupation, language, ...

The Mount Sinai Health System today announced that it will implement Microsoft Dragon Copilot, a new AI clinical assistant designed to streamline clinical documentation, surface critical information, and automate administrative tasks across care settings. The rollout marks a major milestone in Mount Sinai’s ongoing digital transformation and its commitment to using responsible artificial intelligence to support clinicians and deliver better outcomes for patients.  Built on a modern, secure, and scalable architecture purpose-built for healthcare, Dragon Copilot integrates advanced natural language, ambient listening, and generative AI capabilities to help clinicians ...

Researchers at Karolinska Institutet and Yale University have created a multidimensional, molecular map of how the mouse brain develops after birth and how it reacts to inflammation. The study, which is published in Nature, shows that some of the molecular programmes that govern brain development can be reactivated in the brain during inflammation. Brain development is a complex process involving, for example, the precise diversification and distribution of cells into distinct areas. The researchers behind the present study ...

Key points: Metastatic melanoma cells that have spread to lymph nodes survive by relying on a protein called ferroptosis suppressor protein 1 (FSP1)—a finding that points to FSP1 inhibitors as a potentially effective treatment for cancer progression. The study illuminates how metastasizing cancer cells can adapt to survive in lymph nodes, suggesting that treatments can be tailored to exploit cancer’s unique weaknesses according to where it is located in the body. The study also highlights new ways to understand cancerous cell death using in vivo models of cancer metastasis. Boston, ...

Key findings: Scientists captured six high-resolution “snapshots” showing how opioids activate — and how antidotes like Narcan block — a key brain receptor that controls pain and addiction. The study provides the first view of Narcan’s lifesaving action at the molecular level. The discovery offers new avenues for developing painkillers that relieve pain without triggering addiction or dangerous side effects. Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced “mew-opioid”) ...

Osaka, Japan – One monoclonal antibody, rituximab, can work wonders for the treatment of children with frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome. However, what about patients who developed nephrotic syndrome in adulthood? As this drug is not yet approved for use in adult-onset patients, researchers from Japan wanted to highlight the profound benefits that rituximab has in adult-onset patients with these challenging conditions. Nephrotic syndrome is a kidney disorder that causes the body to excrete too much protein in the urine. This condition can lead to edema, weight gain, and an increased risk of infections. ...

About The Study: The expanding use of unregulated psilocybin mushrooms, combined with high variability in composition and common co-use with other substances, raises urgent public health concerns. Existing clinical data are insufficient to guide harm reduction or policy. There is a pressing need to pivot from controlled efficacy trials to real-world research on psilocybin use, including public education, potency testing, and age-specific risk assessment.  Corresponding Author: To contact the corresponding author, Kent E. Hutchison, PhD, email kent.hutchison@cuanschutz.edu. To access the ...