A versatile AI system for analyzing series of medical images
2025-02-27
A new AI-based system for analyzing images taken over time can accurately detect changes and predict outcomes, according to a study led by investigators at Weill Cornell Medicine, Cornell’s Ithaca campus and Cornell Tech. The system’s sensitivity and flexibility could make it useful across a wide range of medical and scientific applications.
The new system, termed LILAC (Learning-based Inference of Longitudinal imAge Changes), is based on an AI approach called machine learning. In the study, which appears Feb. 20 in the Proceedings of the National Academy of Sciences, the researchers developed the system and demonstrated it on diverse time-series of images—also ...
Breakthrough study discovers genetic mutation could be basis for novel treatment of rheumatoid arthritis
2025-02-27
TORONTO, Feb. 27, 2025 – Research led by York University’s Faculty of Health reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice. Lead researcher Ali Abdul-Sater says this discovery could pave the way for a new class of drugs to treat rheumatoid arthritis.
“Rheumatoid arthritis is a common health condition which can interfere with many aspects of daily life and based on the limited efficacy ...
Texas-France space hub aims to innovate space commerce and research
2025-02-27
A new trans-Atlantic space initiative has launched, linking Texas and France in an ambitious effort to fuel startup growth, drive research and forge international partnerships. Announced at the 2025 ASCENDxTexas event Feb. 27, the Texas-France Space Hub aims to unite academic institutions and private enterprises, expanding commercial space presence in both countries.
The three-year initiative fosters global partnerships in aerospace, bringing together Rice University, Stellar Access and Houston Spaceport in Texas with France’s space agency CNES and ...
Young star clusters give birth to rogue planetary-mass objects
2025-02-27
Planetary-mass objects (PMOs) are cosmic nomads: they drift freely through space, unbound to any star, and weigh less than 13 times the mass of Jupiter. While they have been spotted in abundance in young star clusters such as the Trapezium Cluster in Orion (Fig. 1), their origin has puzzled scientists. Traditional theories have suggested that they might be failed stars or planets ejected from their solar systems.
An international team of astronomers, in collaboration with the University of Zurich (UZH), has used advanced simulations to demonstrate that these enigmatic objects can form directly from the violent interactions of disks around young stars. “PMOs don’t ...
Scientists track pneumonia-causing bacteria as they infect the blood stream
2025-02-27
Bacteremia, or blood poisoning, occurs when bacteria overcome the body’s immune defenses.
Bacteremia can worsen into sepsis, a condition that accounts for more than 1 in 3 hospital deaths per year.
Yet people are routinely exposed to and fight off bacteria from the environment without this deadly series of events occurring.
Scientists are trying to figure out exactly how bacteria spread throughout the body to cause systemic infection in the hopes of eventually stopping this process in its tracks.
Michael Bachman, M.D., Ph.D., clinical associate professor of pathology and microbiology and immunology at U-M Medical School and former postdoc Caitlyn Holmes, Ph.D., ...
Nominations sought for 2026 Watanabe Prize in Translational Research
2025-02-27
The Indiana University School of Medicine is accepting nominations until May 15, 2025, for the 2026 August M. Watanabe Prize in Translational Research.
The Watanabe Prize is one of the nation’s largest and most prestigious research awards recognizing senior investigators focused on shepherding scientific discoveries into new therapies for patients. Nominees should be members of the scientific or medical communities who have demonstrated outstanding accomplishments in translational research.
The winner of the 2026 Watanabe Prize in Translational Research will receive a $100,000 award and spend time in Indianapolis from September 16-18, ...
Study finds support for solar energy has become politically polarized
2025-02-27
A new analysis of social media posts finds public support for solar energy remains high, though that support declined significantly from 2016 to 2022. The study also found solar power has become an increasingly polarized issue, with the shift in support being driven largely by opposition to solar power among people in regions that lean Republican.
“The U.S. saw significant growth in the solar energy sector between 2013 and 2022, but that growth has not been spread evenly across the country – some areas have seen more deployment of solar energy technologies than other areas,” says Serena Kim, corresponding author of ...
Advancements in artificial ligaments for ACL reconstruction: A leap towards improved outcomes
2025-02-27
Anterior cruciate ligament (ACL) injuries are common, especially among athletes. Each year, over 400 000 ACL reconstruction (ACLR) surgeries are carried out globally. While the success rate of ACLR is reported to be over 90%, a significant number of patients still face issues like revision surgery and long-term osteoarthritis. This has spurred research into better graft materials, and artificial ligaments have emerged as a potential solution. A recent review article published in Engineering delves into the current state and future prospects of artificial ligaments for ACLR.
Artificial ...
1 gene variant is poised to cure a devastating inherited disease
2025-02-27
1 Gene Variant Is Poised to Cure a Devastating Inherited Disease
Scientists compared five families and multiple generations to find a gene variant that prevents COPA Syndrome and opens the door to a new gene therapy for the condition.
For more than 15 years, Anthony Shum, MD, a pulmonologist at UC San Francisco, has tried to understand the random path of devastation that a rare genetic condition carves through the families it affects.
While many of those who carry the mutation develop severe lung hemorrhaging as children others never get the disease ...
Professional artists viewed as more creative than AI programs
2025-02-27
In the rapidly developing contest between human creativity and artificial intelligence algorithms, professional artists still have an edge in producing more creative AI-assisted artwork than the AI programs themselves or novice artists, according to research published by the American Psychological Association.
The rapid advancement of AI raises some existential questions about the nature of creativity, said lead researcher Paul Seli, PhD, an assistant professor of psychology and neuroscience at Duke University.
“Creativity ...
Closing the gaps — MXene-coating filters can enhance performance and reusability
2025-02-27
Despite improvements to air filtration technology in the aftermath of the COVID-19 pandemic, some of the smallest particles — those of automobile and factory emissions — can still make their way through less efficient, but common filters. An interdisciplinary team of researchers from Drexel University’s College of Engineering have introduced a new way to improve textile-based filters by coating them with a type of two-dimensional nanomaterial called MXene.
Recently published in C Journal ...
Digital Science adds AI-powered summaries to Symplectic Elements to drive research discoverability
2025-02-27
Digital Science has today announced new enhancements to Symplectic Elements, which will now offer the ability to embed AI-generated summaries for publication abstracts within a researcher’s public profile.
Symplectic Elements, a leading research information management system (RIMS), enables the creation of comprehensive public profiles. These profiles are hosted on sleek, modern, and intuitive online portals that offer advanced search and discovery capabilities while ensuring alignment with organizational branding. Profiles can be made available not only for researchers and faculty but also for ...
Solar technology could meet UK’s electricity needs without sacrificing farmland
2025-02-27
New University of Sheffield research shows that combining solar panels with farming (agrivoltaics) can meet UK solar energy targets without sacrificing agricultural land
The coverage potential for the technology is so high that it could meet UK electricity demand more than four times over
Regions identified for the effective deployment of agrivoltaics include Cambridgeshire, Essex, Lincolnshire, and the broader East and South East of England
The approach counters criticism of traditional solar farms, which are often opposed ...
Study finds aged biomass emissions could pose greater risk to lungs than fresh wildfire smoke
2025-02-27
Biomass burning—whether from wildfires, wood stoves or agricultural fires—sends massive amounts of tiny particles and chemicals into the air. These emissions are not just an environmental issue; they pose serious health risks, especially for our lungs. An Environmental Pollution study, co-authored by Dr. Jason Surratt, a professor in the Department of Chemistry at UNC-Chapel Hill, reveals how two key components of biomass smoke—levoglucosan and 4-nitrocatechol—affect human lung cells. Their findings suggest that aged ...
Four research teams rethink particleboard construction and reuse
2025-02-27
For a few hundred dollars, a bedroom can be refreshed with the latest flat-pack offerings. Wood particleboard furniture is affordable and generally easy to assemble, but particleboard is often held together with formaldehyde-based resins that make it hard or impossible to recycle. Now, with the help of science, old pressed-wood furnishings could be repurposed, and new modular decor could incorporate more environmentally friendly materials. Four articles published in ACS journals reveal how. Reporters can request free access to these papers ...
Deep-learning framework advances tissue analysis in spatial transcriptomics
2025-02-27
Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when studying how cells interact and respond to changes in their environment, as well as the intricacies of pathologies like cancer. Spatial transcriptomics (ST) techniques, which have been rapidly evolving over the past decade, allow scientists to map gene activity within tissues while keeping their structure intact, ...
From dormant to danger: How VZV reactivation is driving CNS infections
2025-02-27
The varicella zoster virus (VZV), an infectious virus from the herpes virus family, is primarily known to cause varicella in children and shingles in adults. But lately, this virus has also been reported to trigger severe complications like central nervous system (CNS) infections. Researchers from Fujita Health University, Japan, conducted a comprehensive study spanning 10 years (2013–2022), to identify the VZV-related infections affecting the CNS. Their study reveals a marked increase in adult VZV-related CNS infections, ...
DNA barcodes narrow down possible sources of introductions of an invasive banana skipper butterfly pest
2025-02-27
CABI has led a team of scientists who have used DNA barcodes to narrow down the possible sources of introductions of an invasive banana skipper butterfly, with implications as to the threat of it spreading to Africa and tropical America.
The banana skipper, Erionota torus Evans (Lepidoptera, Hesperiidae, Hesperiinae, Erionotini) is a South-east Asian pest of banana that, in the last 60 years, has spread to the southern Philippines, Taiwan, Japan, India, Sri Lanka, Mauritius and La Réunion.
The new research, published in the journal CABI Agriculture and Bioscience, analysed a partial library of DNA barcodes from the indigenous and introduced ranges and suggests that aircraft are likely ...
Transforming clinical care for children with rare genetic diseases
2025-02-27
Global partnerships that embed scientific research into clinical care are revolutionising the diagnosis and treatments for children with rare genetic diseases, according to a new report.
The white paper found despite advances in genomic technologies, which can detect rare genetic diseases within days, there remained significant challenges to ensuring this leads to improved child health outcomes. But global collaborations, such as the International Precision Child Health Partnership (IPCHiP), using evidence-based approaches to inform decisions in real-time, are overhauling patient care.
The paper was led by Murdoch Children’s Research Institute (MCRI), The Hospital for Sick ...
Polar bear cubs emerging from their dens for the first time: New study captures rare footage
2025-02-27
Svalbard, Norway – February 27, 2025 – Researchers from Polar Bears International, San Diego Zoo Wildlife Alliance, the Norwegian Polar Institute, and the University of Toronto Scarborough reveal the first detailed look at polar bear cubs emerging from their dens, captured through nearly a decade of remote camera footage in Svalbard, Norway. This research, published today on International Polar Bear Day in the Journal of Wildlife Management, marks the first combination of satellite tracking collars with remote camera traps to answer ...
Turning waste organic compound into useful pharmaceuticals and energy using a technique inspired by photosynthesis
2025-02-27
A research team led by Assistant Professor Shogo Mori and Professor Susumu Saito at Nagoya University has developed a groundbreaking method of artificial photosynthesis that uses sunlight and water to produce energy and valuable organic compounds, including pharmaceutical materials, from waste organic compounds. This achievement represents a significant step toward sustainable energy and chemical production. The findings were published in Nature Communications.
“Artificial photosynthesis involves chemical reactions ...
Violence alters human genes for generations, researchers discover
2025-02-27
In 1982, the Syrian government besieged the city of Hama, killing tens of thousands of its own citizens in sectarian violence. Four decades later, rebels used the memory of the massacre to help inspire the toppling of the Assad family that had overseen the operation.
But there is another lasting effect of the attack, hidden deep in the genes of Syrian families. The grandchildren of women who were pregnant during the siege — grandchildren who never experienced such violence themselves — nonetheless bear marks of it in their genomes. ...
Scientists discover key protein in resilience to stress
2025-02-27
When faced with chronic stress, why do some people develop anxiety and depressive symptoms while others show resilience? A protein that acts as a cannabinoid receptor and is present in the structure controlling exchanges between the bloodstream and the brain could be part of the answer, according to a study published today in Nature Neuroscience.
“The protein, called cannabinoid receptor type 1 (CB1), is part of the blood-brain barrier, the dynamic structure that protects the brain by regulating the passage of molecules between the bloodstream and ...
Nasal spray shows preclinical promise for treating traumatic brain injury
2025-02-27
A new study led by researchers at Mass General Brigham suggests a nasal spray developed to target neuroinflammation could one day be an effective treatment for traumatic brain injury (TBI). By studying the effects of the nasal anti-CD3 in a mouse model of TBI, researchers found the spray could reduce damage to the central nervous system and behavioral deficits, suggesting a potential therapeutic approach for TBI and other acute forms of brain injury. The results are published in Nature Neuroscience.
“Traumatic brain injury is a leading cause of death and disability — including cognitive decline ...
Cambridge initiative to address risks of future engineered pandemics
2025-02-27
Covid-19 showed us how vulnerable the world is to pandemics – but what if the next pandemic were somehow engineered? How would the world respond – and could we stop it happening in the first place?
These are some of the questions being addressed by a new initiative launched today at the University of Cambridge, which seeks to address the urgent challenge of managing the risks of future engineered pandemics.
The Engineered Pandemics Risk Management Programme aims to understand the social and biological factors that might drive an engineered pandemic and to make a major contribution ...
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