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UC Davis clinical trial shows biomarkers hold clue in treating aggressive prostate cancer

2025-05-30
Many men with aggressive prostate cancer can experience a high rate of recurrence despite treatment. A new Phase 2 clinical trial at UC Davis Comprehensive Cancer Center unveiled clues as to why these patients are doing poorly and may offer hope in the form of targeted therapy. The findings will be presented at the annual American Society of Clinical Oncology (ASCO) conference on June 3 in Chicago. . Pilot trial sheds new clues                                                                                                                                        ...

UT Health San Antonio researchers discover new links between heart disease and dementia

2025-05-30
SAN ANTONIO, May 30, 2025 – People who are at higher risk for heart disease also seem more likely to develop dementia. And research led by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has discovered new associations between various lipid, or fat, levels in the blood and the risk of developing Alzheimer’s disease, the most common cause of dementia worldwide. The findings mean that using blood lipid profiles could help better understand, predict and possibly even prevent the disease in the future. In more than 800 older adults who were part of the long-running Framingham Heart Study, the researchers ...

AADOCR announces new SCADA/Dentsply Sirona Research Award

2025-05-30
Alexandria, VA – AADOCR and the Student Competition for Advancing Dental Research and its Application (SCADA) Alumni Association are pleased to announce the AADOCR SCADA/Dentsply Sirona Research Award. The new award was created to support dentist-scientists, including SCADA program alumni, in their research careers. The award’s immediate goal is to support early-stage dentist-scientists such as post-doctoral scholars and pre-tenure faculty members, with a long-term objective of increasing the number of successfully funded dentist-scientists ...

Mass General Brigham researchers present key findings at ASCO

2025-05-30
Researchers from Mass General Brigham will present research discoveries and outcomes from clinical trials in cancer at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, held May 30-June 3, in Chicago. ASCO brings together leading experts in clinical oncology to share the latest breakthroughs in cancer research, science and medicine. Presentations from Mass General Brigham investigators include an update on the INCIPIENT trial (using CAR-T in patients with glioblastoma), advances in skin cancer and gynecologic cancer treatment, a new way to radiate multiple brain metastases at the same time, and an app created to help caregivers ...

Student researchers put UTA on national stage

2025-05-30
University of Texas at Arlington biochemistry major Debby Sunday showcased her research at a recent American Chemistry Society conference at East Texas A&M in Commerce. Her findings on photosynthesizers and bacteria earned second place in the undergraduate competition. “This was the first research conference I ever attended, and my experience was very educational,” said Sunday, a graduate of Lake Ridge High School in Mansfield. “Other chemists from across the metroplex presented their various research, from inorganic chemistry to physical chemistry to biochemistry. Not ...

Hertz Foundation and Breakthrough Energy partner to advance climate and energy solutions

2025-05-30
The Hertz Foundation, a nonprofit dedicated to empowering the nation’s most promising innovators in science and technology, and Breakthrough Energy Discovery, a Breakthrough Energy platform focused on pre-venture, early-stage clean technology, have announced a new partnership to advance transformative climate and energy solutions. This collaboration brings together two organizations with a shared commitment to advancing scientific innovation and supporting exceptional talent. By connecting Breakthrough Energy’s innovation platform with the Hertz Foundation’s renowned community of scientific leaders, the partnership will create new opportunities ...

New study reveals how tiny insects detect force

2025-05-30
HUNTINGTON, W.Va. — A newly published study in the Journal of Neurophysiology reveals how blow flies (Calliphora vicina)—despite their minimal body weight—reliably detect forces through specialized sensory organs in their legs. The research offers new insights into insect biomechanics and presents promising applications for the design of next-generation walking robots.  Researchers at Marshall University and West Virginia University examined the behavior of campaniform sensilla—strain-detecting ...

New 3D genome mapping technology sheds light on how plants regulate photosynthesis

2025-05-30
Chinese researchers have developed a groundbreaking technology that sheds light on how the three-dimensional (3D) organization of plant genomes influences gene expression—especially in photosynthesis. The research, which was led by Prof. XIAO Jun at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, in collaboration with BGI Research, was published in Science Advances on May 30.   The innovative method not only provides a more precise tool for understanding the intricate 3D interactions between genes, but also highlights the critical role of long-range chromatin interactions ...

Dinosaur eggshell study confirms biogenic origin of secondary eggshell units

2025-05-30
The calcitic layers of the eggshells of archosaurs (including crocodilians and birds) and turtles are composed of distinctive crystalline structures known as eggshell units. Those growing from the shell membrane are called primary eggshell units (PEUs), while those forming within the calcitic layer are called secondary eggshell units (SEUs). Although rare in modern bird eggs, SEUs are common in dinosaur eggs. Due to the lack of in-depth research on this structure, however, scientists are uncertain whether they are biogenic or abiogenic in origin. To tackle this issue, an international ...

Transforming immunotherapy design

2025-05-30
The University of Pittsburgh’s Natasa Miskov-Zivanov, assistant professor of electrical and computer engineering, has received a prestigious Faculty Early Career Development (CAREER) Award of $581,503 from the National Science Foundation (NSF) for her project titled “Artificial Intelligence-Driven Framework for Efficient and Explainable Immunotherapy Design.” Through her novel approach and the development of an automated system that leverages AI and knowledge graphs to design more effective lymphocytes, she hopes to transform the ...

New book with a global view of men’s experiences with partner violence

2025-05-30
More than two decades ago, Denise Hines began investigating a topic most researchers wouldn’t touch: men as victims of intimate partner violence (IPV). She and collaborator Emily Douglas were the first in the U.S. to earn federal funding for this line of research, publishing studies that challenged entrenched gender assumptions and provoked debate in the field.  Their new book, The Routledge Handbook of Men’s Victimization in Intimate Relationships, offers the most thorough international synthesis ...

New research recovers evidence for lost mountains from Antarctica’s past

2025-05-30
UNIVERSITY OF WISCONSIN-OSHKOSH – A new study led by University of Wisconsin-Oshkosh geologist Timothy Paulsen and University of Colorado Boulder thermochronologist Jeff Benowitz advances the understanding of the geologic history of Transantarctic Mountains bedrock, with implications for understanding the evolution of landscapes lying beneath the ice sheets covering Antarctica.  The team of researchers analyzed the chemistry of mineral grains commonly found in igneous rocks, like granite, from the Transantarctic Mountains. The research team includes other scientists from the University of Arizona, St. Louis University, The Ohio State University, and the University of Alaska ...

Scientists discover new evidence of intermediate-mass black holes

2025-05-30
In the world of black holes, there are generally three size categories: stellar-mass black holes (about five to 50 times the mass of the sun), supermassive black holes (millions to billions of times the mass of the sun), and intermediate-mass black holes with masses somewhere in between. While we know that intermediate-mass black holes should exist, little is known about their origins or characteristics—they are considered the rare “missing links” in black hole evolution. However, four new studies have ...

Predicting underwater landslides before they strike

2025-05-30
Below ocean wind farms, oil rigs and other offshore installations are mammoth networks of underwater structures, including pipelines, anchors, risers and cables, that are essential to harness the energy source. But much like terrestrial structures, these subsea constructions are also vulnerable to natural events, like submarine landslides, that can hamper the productivity of installations below the sea. Researchers at Texas A&M may now be able to accurately predict the occurrence of marine landslides using underwater site characterization data.  “One ...

What will it take to reduce primary care doctor burnout?

2025-05-30
America’s primary care doctors are burning out, cutting back their hours, and leaving their practices early, driven in part by the demands of handling the flood of digital messages from their patients. But a trio of new University of Michigan studies offer hope for easing this crisis, and improving both the care that patients get and the work lives of those who provide it. The studies could help primary care clinics nationwide take steps to keep the bedrock of American health care from crumbling further. All three papers, published in the Journal of ...

Small currents, big impact: Satellite breakthrough reveals hidden ocean forces

2025-05-30
What if some of the smallest ocean currents turned out to be some of the most powerful forces shaping our planet’s climate? This question is at the center of new research co-led by Texas A&M University Department of Oceanography Associate Professor Jinbo Wang, whose work is featured on the cover of the April 17 issue of Nature. It’s a big moment for Wang and his colleagues and the global science community — marking a milestone in a billion-dollar, international water mission two decades in the making, and reflecting Texas A&M University’s long-term strategy ...

Single-atom catalysts change spin state when boosted by a magnetic field

2025-05-30
The job of a catalyst is to ultimately speed up reactions, which could reduce an hour-long process into several minutes. It has recently been shown that using external magnetic fields to modulate spin states of single-atom catalysts (SACs) is highly effective - enhancing oxygen evolution reaction magnetocurrent by a staggering 2,880%. With this in mind, researchers at Tohoku University proposed a completely novel strategy to apply an external magnetic field to modulate spin states, and thereby improve electrocatalytic performance. This study provides valuable insights regarding the development of efficient and sustainable electrochemical technologies ...

Integrated metasurface for quantum analog computation: A new scheme to phase reconstruction

2025-05-30
Researchers have proposed an metasurface-integrated quantum analog computing system. This system ingeniously combines multi-channel metasurfaces with quantum entanglement sources, enabling quantitative phase reconstruction with high signal-to-noise ratio at low signal photon levels. Traditional phase reconstruction often involves complex operation steps, while this technology effectively simplifies the complexity of traditional phase reconstruction. It shows application potential in multiple important fields. For example, in the field of optical chips, it helps improve the performance ...

PolyU research reveals rising soil nitrous acid emissions driven by climate change and fertilisation accelerate global ozone pollution

2025-05-30
Ozone pollution is a global environmental concern that not only threatens human health and crop production, but also worsens global warming. While the formation of ozone is often attributed to anthropogenic pollutants, soil emissions are revealed to be another important source. The Hong Kong Polytechnic University (PolyU) researchers have examined global soil nitrous acid (HONO) emissions data from 1980 to 2016 and incorporated them in a chemistry-climate model to unveil the pivotal role soil HONO emissions play in the increase of the ozone mixing ratio in air and its negative impact on vegetation. Soil ...

The EU should allow gene editing to make organic farming more sustainable, researchers say

2025-05-30
To achieve the European Green Deal’s goal of 25% organic agriculture by 2030, researchers argue that new genomic techniques (NGTs) should be allowed without pre-market authorization in organic as well as conventional food production. NGTs—also known as gene editing-—are classified under the umbrella of GMOs, but they involve more subtle genetic tweaks. In an opinion paper publishing May 30 in the Cell Press journal Cell Reports Sustainability, the researchers describe how NGTs could enable rapid development of crops that are climate resilient, produce higher yields, and require less fertilizers and pesticides.  “This ...

At-home heart attacks and cardiac deaths on the rise since COVID-19 pandemic

2025-05-30
Heart attacks are the leading cause of death globally, yet some statistics from many different countries suggest these events declined in frequency since the COVID-19 pandemic. Mass General Brigham researchers evaluated whether these cardiac trends reflect a true change in event rates, or if they reflect that more people are dying at home rather than in hospitals. Their findings highlight potential shortcomings of cardiac care during and in the years following the height of the pandemic, suggesting ...

Projected outcomes of removing fluoride from U.S. public water systems

2025-05-30
About The Study: This cost-effectiveness analysis found that cessation of public water fluoridation would increase tooth decay and health system costs in the U.S. Despite concerns regarding toxic effects associated with high levels of fluoride, this model demonstrates the substantial ongoing benefits of water fluoridation at safe levels currently recommended by the U.S. Environmental Protection Agency, the National Toxicity Program, and the Centers for Disease Control and Prevention. Corresponding Author: To contact the corresponding author, Lisa Simon, MD, DMD, email lsimon@bwh.harvard.edu. To ...

Parental education, own education, and cognitive function in middle-aged and older adults

2025-05-30
About The Study: In this cohort study of middle-aged and older adults across 4 countries, both higher maternal and paternal education were generally associated with slower cognitive decline, and these associations were mediated by participants’ own education. These findings highlight the long-term relevance of parental education for offspring cognitive health across diverse cultural or socioeconomic contexts, and support the potential benefits of improving educational attainment to reduce intergenerational disparities in late-life cognitive health. Corresponding Author: To contact the corresponding author, ...

Sacred moment experiences among internal medicine physicians

2025-05-30
About The Study: In this national survey of internal medicine physicians, experiencing sacred moments —meaningful, memorable, and sometimes spiritual moments of connection— is common; discussing them with colleagues is not. These findings suggest that frequently experiencing sacred moments and discussing them with colleagues could bolster physician well-being. Corresponding Author: To contact the corresponding author, Jessica Ameling, MPH, email jameling@med.umich.edu. To access the embargoed study: Visit our For The Media website at this ...

Ragon Institute study uncovers how certain antibodies help fight tuberculosis

2025-05-30
Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body’s ability to fight Mycobacterium tuberculosis (Mtb), the bacteria responsible for tuberculosis (TB). Despite decades of research, TB remains one of the deadliest infectious diseases worldwide, with about 10 million new cases and 1.6 million deaths annually. Currently, there is no highly effective vaccine, highlighting the urgent need for new insights and treatments. In a study published today in Immunity, Ragon faculty member Galit ...
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