A team led by Satoya Nakano and Kengo Tachihara at Nagoya University in Japan has revealed new insights into the motion of massive stars in the Small Magellanic Cloud (SMC), a small galaxy neighboring the Milky Way. Their findings suggest that the gravitational pull of the Large Magellanic Cloud (LMC), the SMC’s larger companion, may be tearing the smaller one apart. This discovery reveals a new pattern in the motion of these stars that could transform our understanding of galaxy evolution and interactions. The results were published ...

Researchers at McMaster University have identified six key factors in the first three years of life that influence the trajectory of obesity in South Asian children. The findings offer parents, primary care practitioners and policymakers new insights into addressing childhood obesity for a group of children who have a higher prevalence of abdominal fat and cardiometabolic risk factors, as well as a predisposition to diabetes. “We know that current measures of childhood obesity such as the body mass index (BMI) don’t work well for South Asians because of the so called ‘thin-fat’ phenotype: South Asian newborns are characterized as low birth weight, but proportionally ...

Only 9.5% of plastic materials produced globally in 2022 were manufactured from recycled materials. The findings, reported in Communications Earth & Environment, are part of a comprehensive analysis of the global plastics sector, which also reveals a large increase in the amount of plastic being disposed of by incineration and substantial regional differences in plastic consumption. Plastic production has increased from two million tonnes per year in 1950 to 400 million tonnes per year in 2022 and ...

About The Study: In this cross-sectional survey study, although overall influenza vaccination rates changed little from 2019 to 2022, they increased substantially for Black and Hispanic older adults, particularly those in rural areas, and decreased for some groups of white older adults. Determining the reasons for these divergent changes in influenza vaccination rates is a high priority for future research. Corresponding Author: To contact the corresponding author, Marc N. Elliott, PhD, email elliott@rand.org. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.4462) Editor’s ...

About The Study: In this cohort study of children and adolescents, associations between neighborhood characteristics and mental health evolved from childhood through adolescence. These findings suggest that targeted interventions in disadvantaged neighborhoods and strategies to protect young children from air pollution are essential. A comprehensive approach is recommended to incorporate air pollution, green space, and socioeconomic status not only in residential neighborhoods but also in other settings, such as schools. Corresponding Author: To contact the ...

Background and objectives Patients with acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) are at high risk of bleeding with traditional artificial liver support systems. To address the bleeding risk in liver failure patients, the safety of regional mesylate anticoagulation (RMA) in centrifugation artificial liver support systems (cALSS) is proposed for study. Methods In this prospective single-arm study, ALF and ACLF patients were treated with cALSS using RMA. Coagulation function was monitored, and the predictors of mesylate dose were analyzed ...

April 10, 2025, ONTARIO — A yearlong campaign from the Ontario Institute for Cancer Research (OICR) is celebrating the profound difference cancer research is making in the lives of Ontarians. Cancer Research Changed My Life showcases the people behind research discoveries, bringing their personal stories to life through videos and first-person testimonials. As the province’s cancer research institute, OICR brings together a community of scientists, cancer patients, clinicians and everyday Ontarians to solve cancer ...

Washington, April 10, 2025—The American Educational Research Association (AERA) has announced the winners of its 2025 awards for excellence in education research. “We are pleased to present the 2025 awards to this commendable and exemplary group of education scholars and champions,” said AERA Executive Director Felice J. Levine. “They have contributed tremendously to education research, across all career stages and fields, and continue to make a difference in the lives of students and educators.” AERA will honor the recipients at the Awards Ceremony Luncheon at the 2025 Annual Meeting in Denver on ...

A recent study published in Engineering presents a novel approach to predict Salmonella antimicrobial resistance, a growing concern for public health. The research, led by Le Zhang from Sichuan University, combines large language models (LLMs) and quantum computing to develop a predictive platform. Salmonella is a common foodborne pathogen. The overuse of antimicrobials and genetic mutations have led to the rise of antimicrobial-resistant Salmonella strains, making it crucial to predict resistance accurately for effective treatment. However, traditional methods like bacterial antimicrobial susceptibility tests (ASTs) are inefficient, ...

A study has resulted in the transplantation of 384 m² of Posidonia oceanica seagrass on the scale of an industrial project as part of maritime works in Monaco. This success challenges the idea that these ecosystems are "non-transplantable". This unprecedented experiment, conducted over a period of eight years, opens up new prospects for the preservation of seagrass meadows threatened by coastal urbanisation. As part of the construction project for the "Mareterra" district in Monaco, the marine works involved the destruction of several hectares of Posidonia oceanica meadows, an underwater plant essential to the Mediterranean ...

Everyone wants good quality healthcare, but what exactly is quality and how do you measure it? Is it to do with the waiting time for home care services? Or how many nursing home residents have had medical supervision in the past year? Or whether the medication lists have been checked recently? “These are important aspects that are all worth monitoring. The problem is that quality cannot be easily reduced to a quantifiable value,”said Randi Olsson Haave, an assistant professor and PhD research fellow at the Norwegian University of Science ...

Beijing (China) and Berlin (Germany) April 10, 2025 - Tsinghua University Press (TUP), the leading university press in China, and ResearchGate, the professional network for researchers, has announced an expansion of its Journal Home partnership, which was the first of its kind with a Chinese publisher last year. This expansion more than doubles TUP’s coverage, now including 11 open access titles. Since 1980, TUP has maintained a strong presence in China’s higher education, science, and technology sectors. The expanded partnership will increase the visibility of 10,000+ research articles, spanning nano research, AI, computing, ...

Background Therapy-related B-lymphoblastic leukemia (B-ALL) following treatment for multiple myeloma is a rare occurrence. Despite its rarity and the lack of recognition by the World Health Organization as a distinct disease entity, previous publications indicate its possible emergence following myeloma treatment. Case presentation The patient is a 65-year-old gentleman with a history of IgG kappa multiple myeloma, status post multiple lines of therapy. The patient presented with a fever, and a complete blood count showed cytopenia. Bone marrow morphologic evaluation revealed numerous blasts. ...

Helicobacter pylori (H. pylori) is a widespread bacterial infection associated with gastritis, peptic ulcers, and gastric cancer. While conventional antibiotic-based treatments have been the gold standard for eradication, their efficacy has been steadily declining due to the alarming rise in antibiotic resistance. This has spurred interest in alternative therapies, one of which is fecal microbiota transplantation (FMT). FMT is a novel therapeutic approach that involves transferring microbiota from a healthy donor to a patient’s ...

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent. Due to overlapping morphological, clinical, and immunophenotypic characteristics, distinguishing these disorders from related entities such as T-prolymphocytic leukemia (T-PLL), adult T-cell leukemia/lymphoma (ATLL), Sézary syndrome (SS), and aggressive NK-cell leukemia (ANKL) presents a significant diagnostic challenge. This review integrates recent molecular insights and updates from the WHO 5th edition ...

Chemicals used as food preservatives, flavoring agents, dyes, pesticides, cosmetics, cleaners, and other industrial materials are being increasingly recognized as a health hazard. Their rampant use has led to an increase in the prevalence of various chemical toxicity-induced diseases, including hormonal disruption, cancer, neurological disorders, skin conditions, and occupational poisoning. Numerous chemicals are known to trigger “carcinogenesis” or cancer development by exerting genotoxic effects (direct or indirect interference with DNA replication and damage repair processes ...

Scientists writing a policy forum article in the CABI One Health journal say the “plant world” needs to come out and claim its place at the One Health table as part of a desire to break down barriers that currently limit true cross-domain integration. The researchers say that while plant health is increasingly recognized as a vital part of One Health, it lacks recognition and – historically focussed on health service provision, zoonotic diseases and antimicrobial resistance – One Health overlooks plant health in strategic plans. They add that cross-sectoral approaches, core to One Health, are already used ...

Traumatic brain injury (TBI) is a serious issue affecting thousands of people in the U.S. every year. For military service members, the impact is even more profound. Since 2000, over 492,000 cases of TBI have been reported, making it one of the defining injuries of modern warfare, according to the U.S. Department of Defense. Many veterans have experienced multiple TBIs, raising concerns about long-term effects on brain health. Given the subjective and nonspecific nature of symptom presentation, treatment and prognosis can be difficult. Researchers ...

The first few days of a human embryo’s development, known as pre-implantation, are important. It’s when the first cells are formed, and these decide if the embryo can survive, how it will implant in the womb and how the tissues of the fetus will develop. Today there are still logistical, ethical and legal limitations to using human embryos for research purposes, so scientists use alternative models including stem cell-based and animal models. In a new study published in Nature Cell Biology, Sophie Petropoulos, a researcher ...

Discussion of "alternative facts" has gained sad notoriety in US politics. Yet the question has been around much longer: How do people conduct political debates – is the focus more on facts or personal opinions? A team of international researchers led by the Cluster of Excellence "The Politics of Inequality" looked into the matter. The researchers examined political rhetoric in eight million speeches by members of the US Congress between 1879 and 2022 to see if the focus of their language was more on data and facts or personal convictions and subjective interpretations. The team noticed a significant decline in the use of evidence-based political ...

Nursing poses major metabolic demands on mothers, to which they respond by eating more and saving energy to sustain milk production. There are significant hormonal changes during lactation, but how they lead to metabolic adaptations in nursing mothers remained unclear. In this study, which appeared in Nature Metabolism, leading researchers at Baylor College of Medicine and Pennington Biomedical Research Center uncovered a mechanism that connects prolactin, estrogen, the brain and metabolic adaptations during lactation. “We worked with animal models to investigate ...

UNDER EMBARGO UNTIL THURSDAY 10 APRIL, 10AM LONDON TIME, 5AM EASTERN TIME. Urgent action is needed to protect endangered species, human health and industry from the impacts of the Caspian Sea shrinking, research led by the University of Leeds has found. Water levels in the Caspian Sea – the world’s largest landlocked water body – are getting lower, as hotter temperatures cause more water to evaporate than is flowing in. Even if global warming is limited to below 2°C, ...

New York, NY [April 10, 2025]—A seminal study from researchers at the Icahn School of Medicine at Mount Sinai and their collaborators in the United Kingdom, Belgium, Spain, the Netherlands, and Iceland has uncovered a new genetic cause of neurodevelopmental disorders (NDDs). The discovery offers both closure and hope to potentially thousands of families worldwide who have long been searching for answers. The study, published in the April 10 online issue of Nature Genetics [DOI: 10.1038/s41588-025-02159-5], reveals that mutations in a small, previously overlooked non-coding gene called RNU2-2 are responsible for relatively common NDD. Non-coding genes ...

Researchers have created a “metal detector” algorithm called PRRDetect to hunt down vulnerable tumours, in a development that could one day revolutionise the treatment of cancer. In a paper published today (Thursday 10th April) in Nature Genetics, scientists funded by Cancer Research UK and the National Institute for Health and Care Research (NIHR) analysed the full DNA sequence of 4,775 tumours from seven types of cancer. Based at the University of Cambridge and NIHR Cambridge Biomedical Research Centre, they used that data from Genomics England’s 100,000 Genomes ...

A new USC-led study using functional magnetic resonance imaging (fMRI) reveals the neural mechanisms that contribute to urinary incontinence, a common condition affecting stroke survivors that has a significant impact on their quality of life. The research, just published in Stroke, was conducted by a multidisciplinary team of urologists, neurosurgeons, and imaging experts from the Keck School of Medicine of USC, Keck Medicine of USC, the Rancho Los Amigos National Rehabilitation Center, and the Shirley Ryan Ability Lab. The team discovered significant differences in brain activity during voluntary versus involuntary bladder contractions, presenting potential pathways for targeted therapies. Urinary ...